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Medicina
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Stroke: Diagnostic Approaches and Therapies: 2nd Edition
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Stroke: Diagnostic Approaches and Therapies: 2nd Edition

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Neurology".

Deadline for manuscript submissions: 30 November 2025 | Viewed by 1508

Special Issue Editors

Dr. Anna Podlasek

E-Mail Website
Guest Editor
Image Guided Therapy and Research Facility (IGTRF), University of Dundee, Dundee DD1 4HN, UK
Interests: stroke
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Iris Quasar Grunwald

E-Mail Website
Guest Editor
Tayside Innovation MedTech Ecosystem (TIME), University of Dundee, Dundee DD1 4HN, UK
Interests: neuroscience; stroke; endarterectomy; neuroradiology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

I am writing to invite you to submit a paper to this upcoming Special Issue of the journal Medicina, titled “Stroke: Diagnostic Approaches and Therapies: 2nd Edition”. This Special Issue will focus on the latest advances in the diagnosis and treatment of stroke, including the following topics:

  • New imaging techniques for the early detection of stroke;
  • Novel biomarkers for the prediction of stroke risk;
  • Targeted therapies for the prevention and treatment of stroke;
  • Rehabilitation strategies for stroke survivors.

The aim of this Special Issue is to provide a comprehensive overview of the latest research in the field of stroke and to identify new directions for future research. We solicit papers that report original research, review articles, clinical practice guidelines, commentaries, and letters.

I hope that you will consider submitting a paper to this Special Issue. The deadline for submission is 15 February 2025.

Thank you for your time and consideration.

Dr. Anna Podlasek
Prof. Dr. Iris Quasar Grunwald
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • stroke
  • thrombolysis
  • tenecteplase
  • mechanical thrombectomy
  • neuroprotection
  • neuroimaging

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Further information on MDPI's Special Issue policies can be found here.

Related Special Issue

Published Papers (2 papers)

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14 pages, 1289 KiB  
Article
Clinical and Ultrasound Evaluation of Hemiplegic Shoulder Pain in Stroke Patients: A Longitudinal Observational Study Starting in the First Hours After Stroke
by Filippo Cotellessa, William Campanella, Luca Puce, Maria Cesarina May, Marta Ponzano, Riccardo Picasso, Matteo Mordeglia, Davide Subbrero, Ester Cecchella, Laura Mori, Davide Sassos, Massimo Del Sette, Matteo Formica and Carlo Trompetto
Medicina 2025, 61(3), 484; https://doi.org/10.3390/medicina61030484 - 11 Mar 2025
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Abstract
Background and Objectives: Hemiplegic shoulder pain (HSP) is a common and disabling complication in stroke patients, yet its pathogenesis remains unclear. This longitudinal study aimed to investigate the clinical and ultrasound characteristics of HSP emerging within the first 72 h (T0) post-stroke, [...] Read more.
Background and Objectives: Hemiplegic shoulder pain (HSP) is a common and disabling complication in stroke patients, yet its pathogenesis remains unclear. This longitudinal study aimed to investigate the clinical and ultrasound characteristics of HSP emerging within the first 72 h (T0) post-stroke, with follow-ups at one month (T1) and three months (T2). Materials and Methods: A total of 28 stroke patients with hemiparesis were assessed for HSP. Evaluations included pain severity during passive shoulder mobilization, passive and active range of motion, muscle strength, spasticity, and functional disability. Ultrasound examinations were conducted to assess tendon disorders, bursitis, effusion, glenohumeral subluxation, and adhesive capsulitis. Results: HSP prevalence increased over time, affecting 11% of patients at T0, 32% at T1, and 57% at T2. Higher baseline scores on the National Institutes of Health Stroke Scale (NIHSS), an established marker of stroke severity, were significantly associated with HSP (p < 0.05). At T2, patients with HSP exhibited greater impairment, including restricted passive and active range of movement, pronounced muscle weakness, and increased spasticity (p < 0.05). Ultrasound findings at T2 revealed that adhesive capsulitis and glenohumeral subluxation were significantly more frequent in HSP patients (p < 0.05). Adhesive capsulitis showed a significant increase from 0% at T0 to 21% at T2 (p = 0.031), while glenohumeral subluxation exhibited a non-significant rise from 4% to 21% (p = 0.063). Patients with these conditions experienced significantly greater pain progression (p < 0.001). Conclusions: These findings suggest that capsular pathology plays a key role in the development of HSP within the first three months after stroke. The results highlight the need for targeted interventions addressing glenohumeral subluxation and adhesive capsulitis to alleviate pain and improve rehabilitation outcomes. Full article
(This article belongs to the Special Issue Stroke: Diagnostic Approaches and Therapies: 2nd Edition)
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21 pages, 3850 KiB  
Systematic Review
Thermography in Stroke—A Systematic Review
by Anna Podlasek, Ivo Petrov, Zoran Stankov, Kenneth Snyder, Carlos Alejandro Alvarez, Piotr Musialek and Iris Q. Grunwald
Medicina 2025, 61(5), 854; https://doi.org/10.3390/medicina61050854 - 6 May 2025
Viewed by 98
Abstract
Background and Objectives: Thermography is a non-invasive diagnostic technique that measures skin surface temperatures to reflect normal or abnormal physiology. This review explores the clinical utility of thermography in diagnosing and monitoring stroke, with an emphasis on its clinical applications. Materials and [...] Read more.
Background and Objectives: Thermography is a non-invasive diagnostic technique that measures skin surface temperatures to reflect normal or abnormal physiology. This review explores the clinical utility of thermography in diagnosing and monitoring stroke, with an emphasis on its clinical applications. Materials and Methods: This systematic review followed PRISMA guidelines, with a protocol published prior to analysis. Three databases were screened up to end of 2024. Article selection was conducted in two stages: title and abstract screening using Rayyan®, followed by full-text eligibility assessment. Discrepancies were resolved through consensus. Risk of bias assessment was performed with ROBINS-I. Narrative synthesis was planned in addition to descriptive statistics. Results: A total of 20 studies were included after screening 277 records. Thermography emerged as a promising tool for stroke patients in both the acute and chronic phases. In the acute phase, it demonstrated potential in detecting early signs of carotid occlusive disease by identifying temperature differences in the forehead or neck regions. Additionally, thermography contributed to the differential diagnosis of Wallenberg syndrome. In the chronic phase, it exhibited clinical utility in monitoring rehabilitation progress. Conclusions: Thermography shows promise as a non-invasive tool for stroke assessment and monitoring. While preliminary studies suggest physiological relevance, its clinical utility remains investigational and requires further validation. Full article
(This article belongs to the Special Issue Stroke: Diagnostic Approaches and Therapies: 2nd Edition)
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