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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Diagnosis and Treatment of Endometriosis
edited by and
submission deadline 15 Sep 2026 | 6 articles | Viewed by 10778 | Submission Open
Keywords: endometriosis; adenomyosis; diagnosis; classification; therapy; progesterone
(This special issue belongs to the Section Obstetrics & Gynecology)
Thyroid Disease: Updates from Diagnosis to Treatment: 2nd Edition submission deadline 15 Sep 2026 | 7 articles | Viewed by 9108 | Submission Open
Keywords: autoimmune thyroid diseases; thyroiditis; thyroid cancers; PET/CT; hyperthyroidism
(This special issue belongs to the Section Endocrinology & Metabolism)
Current Challenges in Clinical Dentistry: 3rd Edition
edited by and
submission deadline 15 Sep 2026 | 2 articles | Viewed by 4594 | Submission Open
Keywords: artificial intelligence; clinical dentistry; cutting-edge device and technology; dental material; challenging hypothesis; preventive dentistry; sleep medicine; digital dentistry; smart dentistry; stomatognathic function
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Plastic and Reconstructive Surgery: Clinical Advances and Future Opportunities
edited by Rami S Kantar
submission deadline 15 Sep 2026 | 5 articles | Viewed by 4164 | Submission Open
Keywords: plastic surgery; reconstructive surgery; cleft lips; palates; post-traumatic reconstruction; facial transplantation; craniofacial surgery; cleft surgery
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Latest Advances in Thoracic Surgery: 2nd Edition
edited by
submission deadline 15 Sep 2026 | 2 articles | Viewed by 3987 | Submission Open
Keywords: lung cancer; surgical oncology; robotic surgery; thoracic surgery; lung diseases; minimally invasive surgery
(This special issue belongs to the Section Respiratory Medicine)
Clinical Advances in Obesity and Bariatric Surgery—2nd Edition
edited by Valentin Mocanu and Jerry Dang
submission deadline 15 Sep 2026 | 3 articles | Viewed by 3025 | Submission Open
Keywords: obesity; bariatric surgery; metabolic surgery; anti-obesity medications; obesity treatment
(This special issue belongs to the Section Endocrinology & Metabolism)
Risk Prediction in Mechanical Circulatory Support (MCS) and Cardiac Transplantation
edited by
submission deadline 15 Sep 2026 | 3 articles | Viewed by 2967 | Submission Open
Keywords: advanced heart failure; mechanical circulatory support (MCS); cardiac transplantation; heart transplantation; risk prediction
(This special issue belongs to the Section Cardiology)
Clinical Management and Challenges of Sepsis and Septic Shock submission deadline 15 Sep 2026 | 2 articles | Viewed by 1546 | Submission Open
Keywords: sepsis; septic shock; hemodynamic management; biomarkers; cardiovascular dysfunction; point-of-care ultrasound; precision medicine; emergency medicine; critical care
(This special issue belongs to the Section Intensive Care)
Advances in Pancreatic Cancer: Diagnosis and Therapy
edited by Eleonora Lai, and
submission deadline 15 Sep 2026 | 1 articles | Viewed by 1173 | Submission Open
Keywords: pancreatic cancer diagnosis; endoscopic ultrasound; neoadjuvant chemotherapy; surgical resection; targeted therapy; immunotherapy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Advances in Cardiac Resynchronization Treatment: 2nd Edition
edited by , Konstantinos A. Gatzoulis, Konstantinos Aronis and
submission deadline 15 Sep 2026 | 1 articles | Viewed by 926 | Submission Open
Keywords: conduction system; risk stratification; resynchronization; cardiac pacing; sudden cardiac death
(This special issue belongs to the Section Cardiology)
Cancers: Clinical Radiation Therapy
edited by Julianne M. Pollard-Larkin
submission deadline 15 Sep 2026 | 1 articles | Viewed by 912 | Submission Open
Keywords: reirradiation; tissue tolerance; image registration; treatment planning; dose accumulation
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Esophageal and Upper Gastrointestinal Surgery: Clinical Advances and Practical Updates
edited by and Peter Grimminger
submission deadline 15 Sep 2026 | 1 articles | Viewed by 889 | Submission Open
Keywords: esophageal cancer; gastric cancer; upper GI surgery; surgical oncology; benign upper GI surgery; surgical innovation; surgical outcomes; surgical guidelines; robotic surgery; minimally invasive surgery
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Cardiovascular Disease in MASLD: New Advances in Therapeutic Targets
edited by
submission deadline 15 Sep 2026 | 1 articles | Viewed by 848 | Submission Open
Keywords: MASLD; cardiovascular disease (CVD); metabolic dysfunction; steatotic liver disease; insulin resistance; dyslipidemia; atherosclerosis; inflammation; GLP-1 receptor agonists; SGLT2 inhibitors; lipid-lowering therapies; cardiometabolic risk; clinical trials; therapeutic targets
(This special issue belongs to the Section Cardiovascular Medicine)
Sports Injuries: Emerging Trends in Risk Mitigation, Management and Recovery
edited by and Jose Asian-Clemente
submission deadline 15 Sep 2026 | 1 articles | Viewed by 848 | Submission Open
Keywords: injury prevention; rehabilitation; muscle; return-to-sport; surgery; therapy; testing; regenerative medicine; ultrasound; MRI; sports medicine
(This special issue belongs to the Section Sports Medicine)
Cardiac Arrest: Appropriate Prognostication and Therapeutic Options
edited by and Jin-hong Min
submission deadline 15 Sep 2026 | 1 articles | Viewed by 722 | Submission Open
Keywords: cardiac arrest; prognosis; hypothermia, induced; resuscitation; magnetic resonance imaging; electroencephalog-raphy; blood pressure; hypoxia-ischemia, brain; extracorporeal membrane oxygenation
(This special issue belongs to the Section Cardiovascular Medicine)
Advances in Endoscopic Techniques for Gastrointestinal Diseases
edited by Alberto Tringali
submission deadline 15 Sep 2026 | 1 articles | Viewed by 541 | Submission Open
Keywords: hepatobiliary disease; pancreatic disease; ERCP; interventional EUS; cholangiopancreatoscopy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Advances in Pulmonary Arterial Hypertension: Emerging Therapies and Clinical Outcomes
edited by Namita Sood
submission deadline 15 Sep 2026 | Viewed by 362 | Submission Open
Keywords: pulmonary arterial hypertension (PAH); PAH therapy; emerging treatments; sotatercept; inhaled therapy; targeted pharmacotherapy; combination therapy; therapeutic efficacy; pulmonary vascular imaging
(This special issue belongs to the Section Respiratory Medicine)
Clinical Advances in Endodontics
edited by
submission deadline 15 Sep 2026 | Viewed by 334 | Submission Open
Keywords: endodontics; vital pulp therapy; minimally invasive endodontics; clinical endodontic techniques; bioactive sealers
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
State of the Art of Lung Surgery: Modern Horizons in Lung Cancer Treatment
edited by and Edouard Sage
submission deadline 15 Sep 2026 | Viewed by 306 | Submission Open
Keywords: lung-cancer-surgery; thoracic oncology; RATS; VATS; induction therapy; neoadjuvant-immunotherapy; non-intubated thoracic surgery; NITS; segmentectomy; lung-sparing surgery; 3D-reconstruction
(This special issue belongs to the Section General Surgery)
Recent Clinical Updates on Vascular and Endovascular Surgery submission deadline 15 Sep 2026 | Viewed by 304 | Submission Open
Keywords: vascular surgery; endovascular surgery; aortic disease; abdominal aortic aneurysm; peripheral arterial disease; chronic venous disease; endovascular repair; open vascular surgery
(This special issue belongs to the Section Vascular Medicine)
Innovations and Advancements in Spine Surgery
edited by Mitchell K. Ng
submission deadline 15 Sep 2026 | Viewed by 282 | Submission Open
Keywords: spine surgery; minimally invasive spine surgery; robotic-assisted spine surgery; spinal navigation; endoscopic spine surgery; spinal implant; biologics and regenerative therapies; perioperative optimization; patient-reported outcomes; value-based spine care; surgical innovation
(This special issue belongs to the Section Orthopedics)
Cardiac Imaging in the Clinical Management of Heart Failure
edited by Maria Concetta Pastore
submission deadline 15 Sep 2026 | Viewed by 270 | Submission Open
Keywords: heart failure; cardiac imaging; echocardiography; cardiac magnetic resonance; computed tomography; nuclear imaging
(This special issue belongs to the Section Cardiology)
New Insights into Acute Care and Emergency Surgery: 2nd Edition
edited by Jacob Chen and Avi Benov
submission deadline 15 Sep 2026 | Viewed by 251 | Submission Open
Keywords: trauma surgery; emergency surgery; acute care; anesthesia; ICU
(This special issue belongs to the Section General Surgery)
Innovations in Advanced Heart Failure Detection and Management
edited by Vinh Q. Chau and Nikhil Narang
submission deadline 15 Sep 2026 | Viewed by 229 | Submission Open
Keywords: advanced heart failure; systolic heart failure; mechanical circulatory support; left ventricular assist device; heart transplantation outcomes
(This special issue belongs to the Section Cardiology)
Application of Physiotherapy in Clinical Rehabilitation
edited by
submission deadline 17 Sep 2026 | 1 articles | Viewed by 848 | Submission Open
Keywords: therapeutic exercise; neurological rehabilitation; musculoskeletal physiotherapy; cardiopulmonary rehabilitation; intensive care unit (ICU) rehabilitation; gait and balance; pediatric and geriatric physical therapy; sports physical therapy; rehabilitation technology
(This special issue belongs to the Section Clinical Rehabilitation)
Clinical Advances in Kidney Transplantation submission deadline 18 Sep 2026 | 6 articles | Viewed by 8564 | Submission Open
Keywords: kidney transplantation; immunosuppression; graft survival; donor risk assessment; post-transplant management; rejection and tolerance; precision medicine in transplantation
(This special issue belongs to the Section Nephrology & Urology)
Clinical Perspectives in Pediatric Surgery: From Neonatal Procedures to Adolescent Care submission deadline 18 Sep 2026 | 1 articles | Viewed by 802 | Submission Open
Keywords: mini invasive surgery; transitional care of rare diseases; newborn surgery; long-term follow up; congenital malformations
(This special issue belongs to the Section Clinical Pediatrics)
Current Trends in Implant Dentistry
edited by Marco Toia
submission deadline 20 Sep 2026 | 9 articles | Viewed by 29350 | Submission Open
Keywords: digital implant planning; osseointegration; guided surgery (static and dynamic); bone regeneration; zygomatic and pterygoid implants; 3D previsualization; craniofacial analysis; peri-implant diseases; immediate loading
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Clinical Advancements in Spine Surgery: Best Practices and Outcomes
edited by
submission deadline 20 Sep 2026 | 12 articles | Viewed by 25903 | Submission Open
Keywords: adult spinal deformity; scoliosis; frailty; biological age; big data analysis
(This special issue belongs to the Section Orthopedics)
Acute Pancreatitis and Its Complications: Current Diagnostics and Management
edited by
submission deadline 20 Sep 2026 | 5 articles | Viewed by 19174 | Submission Open
Keywords: acute pancreatitis; pancreas; pancreatic and peripancreatic necrosis; management; less invasive percutaneous radiological and endoscopic approaches
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Applied Cardiorespiratory Physiology in Critical Care Medicine
edited by and Paraskevi Tselioti
submission deadline 20 Sep 2026 | 5 articles | Viewed by 19038 | Submission Open
Keywords: applied physiology; critical care medicine; cardiovascular physiology; respiratory physiology
(This special issue belongs to the Section Anesthesiology)
Skin Disease and Inflammation
edited by
submission deadline 20 Sep 2026 | 4 articles | Viewed by 16219 | Submission Open
Keywords: inflammatory skin diseases; inflammation mechanisms; skin microbiome; psoriasis; eczema; rosacea
(This special issue belongs to the Section Dermatology)
Coronary Artery Disease: Diagnosis, Treatment Challenges, and Emerging Therapy submission deadline 20 Sep 2026 | 5 articles | Viewed by 12211 | Submission Open
Keywords: coronary artery disease; percutaneous coronary intervention; cardiovascular disease; emerging therapies; treatment challenges; biomarkers; interventional cardiology
(This special issue belongs to the Section Cardiology)
Clinical Advances in Musculoskeletal Disorders: 2nd Edition
edited by and Sushrut Babhulkar
submission deadline 20 Sep 2026 | 7 articles | Viewed by 11581 | Submission Open
Keywords: musculoskeletal disorders; disability; pain; inflammation; arthritis
(This special issue belongs to the Section Clinical Rehabilitation)
Advances in Clinical Exercise for Health
edited by and Joana Ribeiro
submission deadline 20 Sep 2026 | 7 articles | Viewed by 11470 | Submission Open
Keywords: clinical exercise science; physical activity; chronic disease prevention; biomechanics; healthy aging; physiology
(This special issue belongs to the Section Sports Medicine)
Current Challenges and New Perspectives in Liver Transplantation
edited by and
submission deadline 20 Sep 2026 | 9 articles | Viewed by 9512 | Submission Open
Keywords: liver transplantation; graft survival; immunosuppression; organ allocation; hepatocellular carcinoma; MASLD; donor shortage; transplant outcomes; innovation
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Perspectives on the Diagnosis and Treatment of Cardiomyopathies
edited by Luca Arcari
submission deadline 20 Sep 2026 | 5 articles | Viewed by 8611 | Submission Open
Keywords: cardiomyopathies; hypertrophic cardiomyopathy; dilated cardiomyopathy; cardiac amyloidosis; arrhythmogenic right ventricular cardiomyopathy; non-dilated left ventricular cardiomyopathy; cardiac magnetic resonance imaging; computed tomography; echocardiography; nuclear imaging
(This special issue belongs to the Section Cardiology)
Thoracic Surgery: State of the Art and Future Directions
edited by and
submission deadline 20 Sep 2026 | 6 articles | Viewed by 8575 | Submission Open
Keywords: thoracic surgery; lung surgery; lung cancer; rib fractures; lung disease; pectus excavatum
(This special issue belongs to the Section Respiratory Medicine)
Cognitive Impairment, Dementia and Depression in Older Adults
edited by Seong Jae Kim and Ilhan Choo
submission deadline 20 Sep 2026 | 3 articles | Viewed by 6525 | Submission Open
Keywords: cognitive impairment; dementia; depression; Parkinson’s disease; artificial intelligence (AI); predictive modeling
(This special issue belongs to the Section Geriatric Medicine)
Advances in Minimally Invasive Gynecologic Surgery: Optimizing Outcomes and Perioperative Strategies
edited by
submission deadline 20 Sep 2026 | 3 articles | Viewed by 5260 | Submission Open
Keywords: minimally invasive gynecologic surgery; MIGS; laparoscopy; robotic surgery; endometrial cancer; endometriosis
(This special issue belongs to the Section Obstetrics & Gynecology)
Maxillomandibular Growth, Reconstruction and Rehabilitation: Orthodontic, Prosthodontic and Surgical Interventions from Childhood to Adulthood
edited by Kamila Chęcińska and
submission deadline 20 Sep 2026 | 5 articles | Viewed by 5146 | Submission Open
Keywords: maxillomandibular growth; orthodontics; prosthodontics; surgical interventions; childhood; adulthood; reconstruction; rehabilitation
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
New Advances in Systemic Lupus Erythematosus (SLE)
edited by
submission deadline 20 Sep 2026 | 2 articles | Viewed by 5102 | Submission Open
Keywords: systemic lupus erythematosus; autoantibodies and biomarkers; lupus nephritis; new and novel treatments; targeted treatment or precision medicine; quality of life
(This special issue belongs to the Section Immunology & Rheumatology)
Modern Gynecological Surgery: Clinical Updates and Perspectives
edited by , and Maya Sophie de Wilde
submission deadline 20 Sep 2026 | 4 articles | Viewed by 4773 | Submission Open
Keywords: gynecological diseases; gynecological surgery; surgical options; individual treatment; women’s health care
(This special issue belongs to the Section Obstetrics & Gynecology)
Advances in Antithrombotic Therapy in Cardiovascular Medicine
edited by Daniele Giacoppo and Antonio Greco
submission deadline 20 Sep 2026 | 6 articles | Viewed by 4032 | Submission Open
Keywords: anticoagulant; antiplatelet; antithrombotic therapy; cardiovascular pharmacotherapy; coronary artery disease; in-flammation; lipid-lowering drugs; lipid metabolism; residual cardiovascular risk; thrombosis
(This special issue belongs to the Section Cardiovascular Medicine)
New Insights into the Management of Psoriasis and Immune-Mediated Dermatoses
edited by Federico Bardazzi and Riccardo Balestri
submission deadline 20 Sep 2026 | 6 articles | Viewed by 3697 | Submission Open
Keywords: psoriasis; immune-mediated inflammatory diseases; biologic therapy; small-molecule drugs; personalized treatment; real-world evidence; comorbidities; patient-centered care
(This special issue belongs to the Section Dermatology)
Liquid Biopsies in Oral Cancer: Advances and New Perspectives submission deadline 20 Sep 2026 | 1 articles | Viewed by 3623 | Submission Open
Keywords: oral cancer; oral potentially malignant disorders; liquid biopsies; saliva and blood biomarkers; circulating tumor cells (CTCs); cell-free DNA (cfDNA)/circulating tumor DNA (ctDNA); cell-free RNA (cfRNA); extracellular vesicles (EVs); genetic and epigenetic biomarkers; early detection; prognosis and therapy response prediction; precision medicine
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Innovations and Advances in Primary Care and Family Medicine
edited by
submission deadline 20 Sep 2026 | 5 articles | Viewed by 3496 | Submission Open
Keywords: primary care; family medicine; integrated care; chronic disease management; multimorbidity; mental health; digital health; artificial intelligence; population health management; implementation research; health services research; interdisciplinary collaboration; evidence-based practice
(This special issue belongs to the Section Epidemiology & Public Health)
Residual Risk in High-Risk Patients Undergoing Percutaneous Coronary Intervention submission deadline 20 Sep 2026 | 1 articles | Viewed by 3443 | Submission Open
Keywords: cardiology; precision medicine; residual risk; acute coronary syndrome; percutaneous coronary intervention; PCI
(This special issue belongs to the Section Cardiology)
Contemporary Oral and Maxillofacial Surgery: Expert Consensus and Best Practices
edited by
submission deadline 20 Sep 2026 | 5 articles | Viewed by 3426 | Submission Open
Keywords: facial trauma; TMJ disorders; implant and sinus surgery; sleep apnea; cosmetic and reconstructive surgery
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Minimally Invasive and Endoscopic Neurosurgery
edited by , Vassilios Tsitouras and Stylianos Kapetanakis
submission deadline 20 Sep 2026 | 1 articles | Viewed by 3375 | Submission Open
Keywords: traumatic brain injury; neuro-oncology; hydrocephalus and cerebrospinal fluid disorders; neuroendoscopy; endo-scopic neurosurgery; skull base surgery; vascular neurosurgery; functional neurosurgery; pediatric neurosurgey; minimally invasive spine surgery; endoscopic spine surgery; spine endoscopy
(This special issue belongs to the Section Clinical Neurology)
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