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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Acute Myocardial Infarction: Diagnosis and Novel Treatment Opportunities
edited by and Flavio Giuseppe Biccirè
submission deadline 10 Mar 2027 | 1 articles | Viewed by 735 | Submission Open
Keywords: acute myocardial infarction; atherosclerosis; percutaneous coronary intervention; atherothrombosis; inflammation; dyslipidemia; lipid-lowering therapy
(This special issue belongs to the Section Cardiology)
Shoulder and Elbow Diseases: Advances in Diagnosis, Treatment and Rehabilitation
edited by , and Joseph A. Abboud
submission deadline 10 Mar 2027 | 1 articles | Viewed by 369 | Submission Open
Keywords: shoulder; elbow; rotator cuff; arthritis; shoulder instability; arthroscopy; arthroplasty; tendinopathy; orthobiologics; rehabilitation; imaging
(This special issue belongs to the Section Orthopedics)
Open, Hybrid and Endovascular Repair of Visceral Artery Aneurysms: State of the Art and Clinical Perspectives
edited by , Francesco Squizzato and Vincenzo Vento
submission deadline 10 Mar 2027 | Viewed by 311 | Submission Open
Keywords: visceral artery aneurysms; endovascular treatment; open surgical repair; hybrid approach; covered stents; end-organ ischemia; long-term durability; patient selection
(This special issue belongs to the Section Vascular Medicine)
Contemporary Clinical Treatment and Rehabilitation of Scoliosis
edited by and Zbigniew Śliwiński
submission deadline 10 Mar 2027 | Viewed by 134 | Submission Open
Keywords: scoliosis; adolescent idiopathic scoliosis; spinal deformity; conservative treatment; physiotherapy; rehabilitation; physi-otherapeutic scoliosis-specific exercises (PSSE); postural control; spinal alignment; biomechanics; neuromuscular reha-bilitation; surface topography; raster stereography; gait analysis; musculoskeletal disorders
(This special issue belongs to the Section Orthopedics)
Artificial Intelligence and Eye Disease: 2nd Edition submission deadline 10 Mar 2027 | Viewed by 129 | Submission Open
Keywords: artificial intelligence; machine learning; deep learning; ophthalmology; eye disease; eye disorders
(This special issue belongs to the Section Ophthalmology)
Clinical Diagnosis and Management of Attention-Deficit/Hyperactivity Disorder (ADHD) submission deadline 10 Mar 2027 | Viewed by 104 | Submission Open
Keywords: ADHD; randomized controlled trials; clinical research; neurodevelopmental disorders; cognitive function; prefrontal cortex; diagnostic methods; therapeutic interventions; evidence-based medicine
(This special issue belongs to the Section Mental Health)
Robotic Surgery in Urologic Diseases: Multidisciplinary Research and Clinical Practice
edited by Donato Cannoletta
submission deadline 10 Mar 2027 | Viewed by 77 | Submission Open
Keywords: robotic surgery; urological surgery; robotic platforms
(This special issue belongs to the Section Nephrology & Urology)
Recent Clinical Advances in Percutaneous Coronary Intervention
edited by and Luke Pickup
submission deadline 15 Mar 2027 | 2 articles | Viewed by 6890 | Submission Open
Keywords: complex PCI; calcium modification; left main stem; stent; coronary artery disease; atherectomy; mechanical circula-tory support device; Impella; DCB; intra-coronary imaging; IVUS; OCT
(This special issue belongs to the Section Cardiology)
Atrial Fibrillation and Heart Failure: Diagnostic and Therapeutic Challenges and Breakthroughs submission deadline 15 Mar 2027 | 3 articles | Viewed by 4717 | Submission Open
Keywords: atrial fibrillation; heart failure; cardiac electrophysiology; ventricular remodelling; rhythm control; catheter abla-tion; neurohormonal activation; biomarkers; ischemia; integrated cardiovascular care
(This special issue belongs to the Section Cardiology)
Recent Clinical Advances in Esophageal Surgery
edited by , James Tankel and Harbi Khalayleh
submission deadline 15 Mar 2027 | 4 articles | Viewed by 3792 | Submission Open
Keywords: esophageal surgery; minimally invasive surgery; esophageal cancer; robotic surgery; endoscopic resection; benign esophageal disorders; paraesophageal hernia; anti-reflux surgery; motility disorders
(This special issue belongs to the Section General Surgery)
Visualizing Cardiac Function: Advances in Modern Imaging Diagnostics
edited by Dafni Charisopoulou and
submission deadline 15 Mar 2027 | 3 articles | Viewed by 3687 | Submission Open
Keywords: cardiac imaging; echocardiography; coronary artery disease; valve disease; heart failure
(This special issue belongs to the Section Cardiology)
Understanding Dermatitis: Symptoms and Effective Treatment Options
edited by and Shinichi Imafuku
submission deadline 15 Mar 2027 | 1 articles | Viewed by 3672 | Submission Open
Keywords: dermatitis; atopic dermatitis; psoriasis; prurigo; JAK inhibitors; real world data
(This special issue belongs to the Section Dermatology)
Minimally Invasive Cardiothoracic Surgery: Current Status and Future Perspectives submission deadline 15 Mar 2027 | 3 articles | Viewed by 1675 | Submission Open
Keywords: aortic-preserving surgery; hybrid cardiovascular surgery; autologous tissue repair; enhanced recovery after surgery; minimally invasive cardiac surgery (MICS); geriatric surgery
(This special issue belongs to the Section Cardiovascular Medicine)
Multiple Sclerosis: Current Diagnosis, Treatment, and Future Options
edited by Przemysław Puz, and
submission deadline 15 Mar 2027 | 3 articles | Viewed by 1586 | Submission Open
Keywords: multiple sclerosis; magnetic resonance imaging (MRI); remyelination; biomarkers; neuroprotection
(This special issue belongs to the Section Clinical Neurology)
Clinical Updates on Epilepsy Research submission deadline 15 Mar 2027 | 2 articles | Viewed by 1403 | Submission Open
Keywords: epilepsy; autoimmune epilepsy; neural autoantibodies; seizure disorders; experimental epilepsy models; animal studies; neuronal excitability; immunotherapy; predictive scoring systems; epilepsy biomarkers
(This special issue belongs to the Section Clinical Neurology)
Glaucoma: Advances in Diagnosis, Management, and Vision Preservation submission deadline 15 Mar 2027 | 2 articles | Viewed by 1251 | Submission Open
Keywords: glaucoma diagnosis; OCT and OCT angiography; laser therapies (SLT, micropulse, cyclophotocoagulation, etc.); minimally invasive glaucoma surgery (MIGS); long-tube devices; artificial intelligence and imaging; pharmacological therapy; visual field and retinal ganglion cell function
(This special issue belongs to the Section Ophthalmology)
Measuring Recovery After Arthroplasty: Optimal Tools and Timing of Outcome Assessment submission deadline 15 Mar 2027 | 1 articles | Viewed by 772 | Submission Open
Keywords: arthroplasty; hip; knee; recovery; outcomes; assessment
(This special issue belongs to the Section Orthopedics)
Outcomes in Pediatric Neurosurgery
edited by and Konstantina Svokos
submission deadline 15 Mar 2027 | 1 articles | Viewed by 467 | Submission Open
Keywords: functional outcomes; pediatric neurosurgery; quality of life; innovative technologies; global neurosurgery
(This special issue belongs to the Section Clinical Pediatrics)
Delaying the Progression to Castration Resistance: Integrating Multidisciplinary Strategies and Tumor Survival Mechanisms in High-Risk Prostate Cancer
edited by Tag Keun Yoo
submission deadline 15 Mar 2027 | 1 articles | Viewed by 415 | Submission Open
Keywords: high-risk prostate cancer; oligometastasis; cytoreductive prostatectomy; multidisciplinary therapy; ADT; ARPI; docetaxel resistance; tumor survival mechanisms; CRPC progression
(This special issue belongs to the Section Oncology)
From Gastritis to Gastric Cancer: Challenges in Diagnosis and Long-Term Management submission deadline 15 Mar 2027 | Viewed by 318 | Submission Open
Keywords: gastric cancer; gastritis and H. pylori; early detection and endoscopy; multimodal treatment; molecular profiling (MSI/MMR, PD-L1, CLDN18.2, HER2)
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Advances and Emerging Trends in Neuropsychology submission deadline 15 Mar 2027 | 1 articles | Viewed by 310 | Submission Open
Keywords: neuropsychology; affective neuroscience; social neuroscience; brain–behavior relationship; emotional processing; emotion regulation; memory; personalized mental health; therapeutic factors
(This special issue belongs to the Section Mental Health)
Diagnostic and Rehabilitation of Vestibular Disorders
edited by
submission deadline 15 Mar 2027 | Viewed by 167 | Submission Open
Keywords: persistent postural-perceptual dizziness; vestibular migraine; vestibular disorders; motion perception; vestibular reha-bilitation; visually induced dizziness and visual dependence
(This special issue belongs to the Section Otolaryngology)
Biological Therapies in Psoriasis: Cardiovascular Aspects, Biomarkers, and the Patient Perspective submission deadline 15 Mar 2027 | Viewed by 139 | Submission Open
Keywords: psoriasis; comorbidities; quality of life; biomarkers; pathogenesis; systemic immunosuppressive treatment; biologics; patient outcomes
(This special issue belongs to the Section Dermatology)
Technology-Enhanced Clinical Rehabilitation: Innovations, Applications and Outcomes
edited by Adam Wrzeciono and Joanna Szczepańska-Gieracha
submission deadline 15 Mar 2027 | Viewed by 132 | Submission Open
Keywords: clinical rehabilitation; digital health; virtual reality; augmented reality; artificial intelligence; tele-rehabilitation; wearable technologies; rehabilitation robotics; digital therapeutics; technology-assisted rehabilitation; psychosocial aspects; remote monitoring
(This special issue belongs to the Section Clinical Rehabilitation)
Advances in Transcatheter and Surgical Aortic Valve Replacement submission deadline 15 Mar 2027 | Viewed by 81 | Submission Open
Keywords: aortic stenosis; TAVI; SAVR; minimally invasive; biomarker
(This special issue belongs to the Section Cardiology)
Personalized Medicine: Future Perspectives on Personalized Oral and Maxillofacial Surgery
edited by , Rareș Calin Roman and Mihaela Carmen Hedeşiu
submission deadline 19 Mar 2027 | 1 articles | Viewed by 2340 | Submission Open
Keywords: head and neck surgery; head and neck oncology; head and neck reconstructions; personalized medicine; artificial intelligence; head and neck trauma; integrative medicine
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Pulmonary Hypertension: From Pathophysiology to Clinical Management
edited by and
submission deadline 19 Mar 2027 | 1 articles | Viewed by 1389 | Submission Open
Keywords: pulmonary hypertension; pulmonary arterial hypertension; chronic thromboembolic pulmonary hypertension; pulmonary endarterectomy; balloon pulmonary angioplasty; pharmacological treatment; pathophysiology
(This special issue belongs to the Section Respiratory Medicine)
Insights and Innovations in Sports Cardiology submission deadline 20 Mar 2027 | 7 articles | Viewed by 14968 | Submission Open
Keywords: sports cardiology; athlete heart; cardiovascular screening; arrhythmias; sudden cardiac death; cardiac rehabilitation; exercise prescription; mobile health; preventive cardiology; personalized medicine; pediatric fitness
(This special issue belongs to the Section Sports Medicine)
Acute Myocardial Infarction: Diagnosis, Treatment, and Rehabilitation
edited by
submission deadline 20 Mar 2027 | 9 articles | Viewed by 12009 | Submission Open
Keywords: acute myocardial infarction; coronary angioplasty; acute heart failure; cardiogenic shock; rehabilitation programs
(This special issue belongs to the Section Cardiovascular Medicine)
Acute Coronary Syndrome(ACS): From Emergency Intervention to Long-Term Prevention
edited by Marco Ciardetti and Alessio Mattesini
submission deadline 20 Mar 2027 | 4 articles | Viewed by 8974 | Submission Open
Keywords: acute coronary syndrome; primary percutaneous coronary intervention; antithrombotic therapy; secondary prevention; risk stratification
(This special issue belongs to the Section Cardiology)
Sarcopenia, Musculoskeletal, and Neuromuscular Disorders: Physical Therapy and Rehabilitation Perspectives submission deadline 20 Mar 2027 | 2 articles | Viewed by 7429 | Submission Open
Keywords: sarcopenia; musculoskeletal diseases; neuromuscular disorders; muscle mass; low back pain; neck pain; gait and balance; physical therapy; rehabilitation medicine
(This special issue belongs to the Section Clinical Rehabilitation)
Artificial Intelligence in Gastrointestinal Disorders: Current Updates from Theory to Clinical Practice submission deadline 20 Mar 2027 | 5 articles | Viewed by 5717 | Submission Open
Keywords: artificial intelligence; gastroenterology; medical imaging; endoscopy; prognostic modeling; ethical considerations
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Obesity-Related Metabolic and Cardiovascular Disorders
edited by and Federica Vinciguerra
submission deadline 20 Mar 2027 | 5 articles | Viewed by 5065 | Submission Open
Keywords: obesity; type 2 diabetes mellitus; insulin resistance; metabolic syndrome; cardiovascular disease; lipid disorder; adipose tissue dysfunction; visceral adiposity; cardiometabolic risk; endothelial dysfunction; health disparities; gut microbiota; bariatric surgery; precision medicine
(This special issue belongs to the Section Cardiovascular Medicine)
State of the Art in Spinal Cord Injuries: Clinical Rehabilitation and Management
edited by
submission deadline 20 Mar 2027 | 6 articles | Viewed by 4477 | Submission Open
Keywords: neurorehabilitation; assistive technologies; neuroplasticity; neuromodulation; spinal cord injury
(This special issue belongs to the Section Clinical Rehabilitation)
Pre-Hospital and In-Hospital Emergency Care Research
edited by , and Yohei Okada
submission deadline 20 Mar 2027 | 7 articles | Viewed by 4312 | Submission Open
Keywords: pre-hospital; in-hospital; emergency care; emergency medical services; acute care
(This special issue belongs to the Section Emergency Medicine)
Diagnosis, Treatment and Prognosis of Head and Neck Cancer
edited by and Elena Russo
submission deadline 20 Mar 2027 | 5 articles | Viewed by 3801 | Submission Open
Keywords: head and neck neoplasms; surgical procedures; minimally invasive surgical procedures; radiotherapy; immunotherapy; biomarkers; treatment outcome; early diagnosis; prognosis; quality of life
(This special issue belongs to the Section Oncology)
Advances in Pacemaker Implantation: Past, Present, and Future Challenges
edited by Rahul N. Doshi and
submission deadline 20 Mar 2027 | 1 articles | Viewed by 3714 | Submission Open
Keywords: pacing; physiologic pacing; left bundle area pacing; leadless pacing; lead management
(This special issue belongs to the Section Cardiology)
Trauma Surgery: Strategies, Challenges and Vision of the Future
edited by and Yaniv S. Warschawski
submission deadline 20 Mar 2027 | 3 articles | Viewed by 3587 | Submission Open
Keywords: orthopaedic surgery; fractures; injuries; upper limb; trauma
(This special issue belongs to the Section Clinical Research Methods)
Clinical Updates in Fractures: Orthopedics, Trauma Surgery, and Rehabilitation
edited by
submission deadline 20 Mar 2027 | 3 articles | Viewed by 3123 | Submission Open
Keywords: orthopedic surgery; global orthopedic health; surgical techniques; outreach; inreach; artificial intelligence; robotics; outcome measures
(This special issue belongs to the Section Orthopedics)
Misconceptions and Myths in Dermatology: From Clinic to Clarity
edited by Simon M. Mueller and Oliver Brandt
submission deadline 20 Mar 2027 | 1 articles | Viewed by 3061 | Submission Open
Keywords: misconceptions; misunderstanding; myths; errors; mistakes; skin; dermatology
(This special issue belongs to the Section Dermatology)
Clinical Diagnosis and Treatment in Oncology: Radiotherapy and Imaging Analysis submission deadline 20 Mar 2027 | 1 articles | Viewed by 2915 | Submission Open
Keywords: radiomics; metabolic imaging; radiotherapy; predictive factors; response models; PET-CT; artificial intelligence; biomarkers; machine-learning
(This special issue belongs to the Section Oncology)
Recent Advances in Adverse Pregnancy and Neonatal Outcomes
edited by
submission deadline 20 Mar 2027 | 2 articles | Viewed by 2776 | Submission Open
Keywords: maternal and fetal; adverse pregnancy; neonatal outcomes; newborns; cesarean section
(This special issue belongs to the Section Obstetrics & Gynecology)
Spine Surgery: Clinical Advances and Practice Updates
edited by
submission deadline 20 Mar 2027 | 3 articles | Viewed by 2691 | Submission Open
Keywords: spine surgery; minimally invasive spine surgery; endoscopic spine surgery; robotics; artificial intelligence; spinal deformity; scoliosis; spinal trauma
(This special issue belongs to the Section Orthopedics)
Current Advances in Non-Trauma Emergency Critical and Resuscitation Medicine
edited by
submission deadline 20 Mar 2027 | 1 articles | Viewed by 2562 | Submission Open
Keywords: resuscitation; non-trauma critically ill; emergency department; resuscitation room management; neuro-critical emergency care; emergency department critical care
(This special issue belongs to the Section Emergency Medicine)
Clinical Challenges in Heart Failure Management: 2nd Edition
edited by Paolo Severino, Gaetano M. Ruocco and
submission deadline 20 Mar 2027 | 2 articles | Viewed by 2507 | Submission Open
Keywords: acute heart failure; chronic heart failure; inotropic support; left ventricular assist device; cardiac contractility modulation; guanylate cyclase stimulators; quality of life; telemedicine; palliative care
(This special issue belongs to the Section Cardiology)
Current Challenges in Adult Congenital Heart Diseases submission deadline 20 Mar 2027 | 3 articles | Viewed by 2277 | Submission Open
Keywords: adult congenital heart disease; quality of life; pregnancy in congenital heart disease; heart failure; arrhythmia; septal defect; congenital valve stenosis; coarctation of the Aorta; Fontan circulation; Tetralogy of Fallot
(This special issue belongs to the Section Cardiology)
Current Updates on Pediatric Neurological Disorders and Neurorehabilitation submission deadline 20 Mar 2027 | 2 articles | Viewed by 1826 | Submission Open
Keywords: child neurological disorders; neurorehabilitation; neurogenetics; treatment; quality of life; rehabilitation teams; congenital brain disorders; trauma; movement disorders; cerebral palsy
(This special issue belongs to the Section Clinical Pediatrics)
Perspectives in Bionic Reconstruction and Post-Amputation Management
edited by and Jennifer Ernst
submission deadline 20 Mar 2027 | 2 articles | Viewed by 1804 | Submission Open
Keywords: bionic reconstruction; advanced prosthetics; neurorehabilitation; sensory feedback; motor control
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Clinical Advances in Lower Limb Trauma and Orthopedic Surgery: From Bench to Bedside
edited by and
submission deadline 20 Mar 2027 | 3 articles | Viewed by 1793 | Submission Open
Keywords: lower limb trauma; fracture fixation; arthroplasty; biomechanics; orthopaedic surgery; clin-ical outcomes; minimally invasive techniques; rehabilitation
(This special issue belongs to the Section Orthopedics)
Minimally Invasive Spine Surgery: Evidence, Advances and Controversies
edited by , Constantine Constantoyannis, and Oliver Lasry
submission deadline 20 Mar 2027 | 1 articles | Viewed by 1675 | Submission Open
Keywords: spine surgery; minimally invasive; MIS; MISS; endoscopic; tubular; fusion; laminectomy; discectomy; decompression; percutaneous; robotic; robotic-assisted; navigation; augmented-reality
(This special issue belongs to the Section Clinical Neurology)
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