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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Novel Developments in Dental and Oral Surgery submission deadline 15 Mar 2026 | 1 articles | Viewed by 1314 | Submission Open
Keywords: guided bone regeneration; dental implant osseointegration; laser dentistry; maxillofacial reconstruction; sinus lift techniques
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Risk Prediction in Mechanical Circulatory Support (MCS) and Cardiac Transplantation
edited by
submission deadline 15 Mar 2026 | 1 articles | Viewed by 1125 | Submission Open
Keywords: advanced heart failure; mechanical circulatory support (MCS); cardiac transplantation; heart transplantation; risk prediction
(This special issue belongs to the Section Cardiology)
Oral Hygiene: Updates and Clinical Progress: 2nd Edition
edited by
submission deadline 15 Mar 2026 | 1 articles | Viewed by 968 | Submission Open
Keywords: periodontal disease; dental caries; plaque control; oral hygiene practices; gingivitis; dental prophylaxis; oral health education
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Current Challenges and Future Directions in Lung Resections in Thoracic Surgery
edited by Vasileios K. Kouritas and Emmanuel Michael Kefaloyannis
submission deadline 15 Mar 2026 | 1 articles | Viewed by 891 | Submission Open
Keywords: robotic-assisted thoracic surgery (RATS); robotic; sublobar; 3D; emphysema; endobronchial valves; lung volume reduction surgery (LVRS); high-risk; AI; research; lung; screening; lung cancer
(This special issue belongs to the Section General Surgery)
Thyroid Disease: Updates from Diagnosis to Treatment: 2nd Edition submission deadline 15 Mar 2026 | 2 articles | Viewed by 671 | Submission Open
Keywords: autoimmune thyroid diseases; thyroiditis; thyroid cancers; PET/CT; hyperthyroidism
(This special issue belongs to the Section Endocrinology & Metabolism)
Research Progress in Kawasaki Disease: Epidemiology, Treatment and Cardiovascular Outcomes
edited by Andre Jakob
submission deadline 15 Mar 2026 | 1 articles | Viewed by 608 | Submission Open
Keywords: Kawasaki disease; immune pathogenesis; immunomodulatory treatment; coronary artery pathology; cardiovascular outcomes
(This special issue belongs to the Section Clinical Pediatrics)
Latest Advances in Thoracic Surgery: 2nd Edition
edited by
submission deadline 15 Mar 2026 | 1 articles | Viewed by 359 | Submission Open
Keywords: lung cancer; surgical oncology; robotic surgery; thoracic surgery; lung diseases; minimally invasive surgery
(This special issue belongs to the Section Respiratory Medicine)
Cardiovascular Disease in MASLD: New Advances in Therapeutic Targets
edited by
submission deadline 15 Mar 2026 | Viewed by 101 | Submission Open
Keywords: MASLD; cardiovascular disease (CVD); metabolic dysfunction; steatotic liver disease; insulin resistance; dyslipidemia; atherosclerosis; inflammation; GLP-1 receptor agonists; SGLT2 inhibitors; lipid-lowering therapies; cardiometabolic risk; clinical trials; therapeutic targets
(This special issue belongs to the Section Cardiovascular Medicine)
Clinical Diagnosis and Treatment of Uveitis
edited by
submission deadline 15 Mar 2026 | Viewed by 97 | Submission Open
Keywords: uveitis; intraocular tumors; medical retina; pediatric retina
(This special issue belongs to the Section Ophthalmology)
Advances in Antithrombotic Therapy in Cardiovascular Medicine
edited by Daniele Giacoppo and Antonio Greco
submission deadline 15 Mar 2026 | Viewed by 88 | Submission Open
Keywords: anticoagulant; antiplatelet; antithrombotic therapy; cardiovascular pharmacotherapy; coronary artery disease; in-flammation; lipid-lowering drugs; lipid metabolism; residual cardiovascular risk; thrombosis
(This special issue belongs to the Section Cardiovascular Medicine)
Early-Stage Non-Small Cell Lung Cancer: Diagnostic Challenges and Therapeutic Innovations
edited by Efimia Boutsikou, Georgia F. Hardavella and
submission deadline 15 Mar 2026 | Viewed by 74 | Submission Open
Keywords: non-small cell lung cancer (NSCLC); early-stage lung cancer; diagnostic imaging; stereotactic ablative radiotherapy (SABR); molecular profiling; adjuvant targeted therapy; immunotherapy in early-stage NSCLC
(This special issue belongs to the Section Respiratory Medicine)
Urologic Oncology: From Diagnosis to Treatment
edited by Matteo Vittori and Valerio Iacovelli
submission deadline 15 Mar 2026 | Viewed by 64 | Submission Open
Keywords: prostate cancer; kidney cancer; bladder cancer; testicular cancer
(This special issue belongs to the Section Nephrology & Urology)
Progress in Clinical Diagnosis and Therapy in Ophthalmology
edited by
submission deadline 16 Mar 2026 | 2 articles | Viewed by 941 | Submission Open
Keywords: ophthalmic imaging; artificial intelligence in ophthalmology; retinal diseases; corneal transplantation; glaucoma diagnostics; ocular therapeutics; personalized medicine; ocular genetics
(This special issue belongs to the Section Ophthalmology)
Movement Analysis in Rehabilitation
edited by Paola Contessa
submission deadline 16 Mar 2026 | Viewed by 88 | Submission Open
Keywords: clinical biomechanics; engineering methods; human movement; motor control; muscle force; musculoskeletal disorders; neuromuscular diseases; posture and balance; rehabilitation
(This special issue belongs to the Section Orthopedics)
Clinical Practices of Critical Care in Emergency Medicine
edited by
submission deadline 17 Mar 2026 | 1 articles | Viewed by 831 | Submission Open
Keywords: non-invasiveness; non-ICU critically ill patient; organ replacement versus organ support; prognostic assessment; vasopressors; inotropes; and vasoactive agents; emergency department
(This special issue belongs to the Section Intensive Care)
Neurocritical Care: Clinical Advances and Practice Updates: 2nd Edition
edited by Ali Seifi
submission deadline 18 Mar 2026 | Viewed by 131 | Submission Open
Keywords: traumatic brain injury (TBI); intracerebral hemorrhage (ICH); neurocritical care practice; neurocritical care; neurosurgical innovations; artificial intelligence; medical device and technology innovation in neurocritical care; stroke management; subarachnoid hemorrhage (SAH); status epilepticus
(This special issue belongs to the Section Clinical Neurology)
Clinical Perspectives in Stroke Rehabilitation
edited by Krystyna Jaracz, and Robert Ślusarz
submission deadline 20 Mar 2026 | 9 articles | Viewed by 19742 | Submission Open
Keywords: stroke; clinical perspectives; therapy; functional outcome predictors; rehabilitation; quality of life
(This special issue belongs to the Section Clinical Rehabilitation)
Sleep in Neurology—Sleep Disorders and Dysfunction of the Nervous System
edited by
submission deadline 20 Mar 2026 | 6 articles | Viewed by 15747 | Submission Open
Keywords: sleep; neurology; insomnia; restless leg syndrome; REM sleep behavior disorder; parasomnia; somnambulism; neurodegenerative disorders; brain injury; sleep-related movement disorders
(This special issue belongs to the Section Clinical Neurology)
Musculoskeletal Rehabilitation and Regenerative Medicine: Current Challenges and New Perspectives
edited by and Gianpaolo P. Ronconi
submission deadline 20 Mar 2026 | 5 articles | Viewed by 14768 | Submission Open
Keywords: musculoskeletal diseases; rehabilitation; enhanced recovery after surgery; chronic pain; disability; regenerative medicine; personalized medicine
(This special issue belongs to the Section Clinical Rehabilitation)
Current Trends in Implant Dentistry
edited by Marco Toia
submission deadline 20 Mar 2026 | 5 articles | Viewed by 13991 | Submission Open
Keywords: digital implant planning; osseointegration; guided surgery (static and dynamic); bone regeneration; zygomatic and pterygoid implants; 3D previsualization; craniofacial analysis; peri-implant diseases; immediate loading
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Moving Forward to New Trends in Pulmonary Diseases submission deadline 20 Mar 2026 | 6 articles | Viewed by 12900 | Submission Open
Keywords: pulmonary tuberculosis; chronic obstructive airway diseases; bronchiectasis; COVID-19; sleep apnea; ultrasound; lung cancer; pulmonary rehabilitation
(This special issue belongs to the Section Respiratory Medicine)
Risk Prediction for Gynecological Cancer
edited by
submission deadline 20 Mar 2026 | 7 articles | Viewed by 12318 | Submission Open
Keywords: cervical cancer; endometrial cancer; tubo-ovarian cancer; diagnosis; treatment; prognosis
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Management of Prosthetic Joint Infection (PJI)
edited by Daniel Pérez-Prieto
submission deadline 20 Mar 2026 | 7 articles | Viewed by 10759 | Submission Open
Keywords: prosthetic joint infection; debridement; biofilm; wound healing; multidisciplinary team; osteomyelitis
(This special issue belongs to the Section Orthopedics)
Chronic Kidney Disease: Clinical Challenges and Management submission deadline 20 Mar 2026 | 5 articles | Viewed by 9509 | Submission Open
Keywords: chronic kidney disease; clinical trial; end-stage renal disease; kidney dysfunction; management; challenge
(This special issue belongs to the Section Nephrology & Urology)
Innovation in Hand Surgery
edited by Rocco De Vitis and Marco Passiatore
submission deadline 20 Mar 2026 | 7 articles | Viewed by 9145 | Submission Open
Keywords: hand surgery; hand reconstruction; hand deformities; reconstructive surgery; peripheral nerve surgery; hand tumors; thumb arthritis; wrist arthritis; arthroscopy; prosthesis
(This special issue belongs to the Section Orthopedics)
Anterior Cruciate Ligament (ACL) Injuries: Clinical Treatment and Rehabilitation
edited by Young-Jin Seo
submission deadline 20 Mar 2026 | 6 articles | Viewed by 7844 | Submission Open
Keywords: anterior cruciate ligament (ACL); reconstruction; lateral extra-articular procedures; all-inside technique; internal bracing; slope reducing osteotomy; biologic augmentation; rehabilitation
(This special issue belongs to the Section Orthopedics)
Surgical Treatment for Lung Cancer
edited by , Cezary Piwkowski and Marek Ochman
submission deadline 20 Mar 2026 | 5 articles | Viewed by 7282 | Submission Open
Keywords: lung cancer; surgery; minimally invasive surgery; immunotherapy; enhanced recovery after surgery; segmentectomy
(This special issue belongs to the Section Respiratory Medicine)
Gastrointestinal Endoscopy: Clinical Advances in Diagnosis and Treatment, 2nd Edition
edited by Joao Santos-Antunes and
submission deadline 20 Mar 2026 | 2 articles | Viewed by 6932 | Submission Open
Keywords: diagnostic endoscopy; therapeutic endoscopy; gastrointestinal neoplasia; endoscopic mucosal resection; endoscopic submucosal dissection; early cancer; subepithelial lesions
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Applied Cardiorespiratory Physiology in Critical Care Medicine
edited by and Paraskevi Tselioti
submission deadline 20 Mar 2026 | 3 articles | Viewed by 6863 | Submission Open
Keywords: applied physiology; critical care medicine; cardiovascular physiology; respiratory physiology
(This special issue belongs to the Section Anesthesiology)
Clinical Advancements in Spine Surgery: Best Practices and Outcomes
edited by
submission deadline 20 Mar 2026 | 7 articles | Viewed by 6673 | Submission Open
Keywords: adult spinal deformity; scoliosis; frailty; biological age; big data analysis
(This special issue belongs to the Section Orthopedics)
New Advances in Musculoskeletal Physiotherapy: Exercise, Manual Therapy and Invasive Physiotherapy
edited by and Ignacio Cancela-Cilleruelo
submission deadline 20 Mar 2026 | 4 articles | Viewed by 6536 | Submission Open
Keywords: musculoskeletal disorders; exercise therapy; manual therapy; invasive physical therapy; rehabilitation
(This special issue belongs to the Section Orthopedics)
Echocardiographic Imaging in Transcatheter Structural Intervention: Current Practices and Future Directions
edited by and Fausto Pizzino
submission deadline 20 Mar 2026 | 3 articles | Viewed by 5914 | Submission Open
Keywords: echocardiographic imaging; transcatheter intervention; aortic stenosis; mitral regurgitation; tricuspid regurgitation; left atrial appendage closure; patent foramen ovale closure; atrial septal defect repair
(This special issue belongs to the Section Cardiology)
Innovations in the Treatment for Depression and Anxiety
edited by Lucie Bartova
submission deadline 20 Mar 2026 | 2 articles | Viewed by 5882 | Submission Open
Keywords: depression; anxiety; antidepressant; anxiolytic; psychopharmacotherapy; psychotherapy; brain stimulation; treatment; response; resistance
(This special issue belongs to the Section Mental Health)
Renal Cell Carcinoma: From Diagnostic to Therapy
edited by Ithaar H. Derweesh and Zachary A. Hamilton
submission deadline 20 Mar 2026 | 4 articles | Viewed by 5679 | Submission Open
Keywords: biomarkers; clinical practice patterns; diagnosis; kidney cancer; metastasis; renal cell carcinoma; renal mass; staging; systemic therapy; surveillance
(This special issue belongs to the Section Nephrology & Urology)
Improving Diagnosis and Treatment of Vestibular Disorder: Latest Advances and Challenges
edited by , and Athanasia Korda
submission deadline 20 Mar 2026 | 2 articles | Viewed by 4913 | Submission Open
Keywords: vestibular system; balance disorders; dizziness; vertigo; vestibular testing; videonystagmography; video head impulse test; vestibular evoked myogenic potentials; vestibular rehabilitation therapy
(This special issue belongs to the Section Otolaryngology)
Skin Disease and Inflammation
edited by
submission deadline 20 Mar 2026 | 1 articles | Viewed by 4845 | Submission Open
Keywords: inflammatory skin diseases; inflammation mechanisms; skin microbiome; psoriasis; eczema; rosacea
(This special issue belongs to the Section Dermatology)
Chronic Kidney Disease: Clinical Updates and Perspectives, Opportunities and Challenges, 2nd Edition
edited by Botond Csiky
submission deadline 20 Mar 2026 | 2 articles | Viewed by 4495 | Submission Open
Keywords: chronic kidney disease progression; cardiovascular risk factors; diabetes mellitus; obesity; kidney transplantation; survival; pathophysiology of CKD; hemodialysis; peritoneal dialysis; metabolic and mineral bone disease
(This special issue belongs to the Section Nephrology & Urology)
Advanced Strategy for Diagnosis and Treatment of Obstructive Sleep Apnea Syndrome (OSAS)
edited by
submission deadline 20 Mar 2026 | 3 articles | Viewed by 4405 | Submission Open
Keywords: obstructive sleep apnea syndrome; diagnosis; obesity; treatment; CPAP; comorbidities; cardiovascular risk
(This special issue belongs to the Section Respiratory Medicine)
The Role of Scleral Lenses in the Management of Eye Disease
edited by Cherie B. Nau
submission deadline 20 Mar 2026 | 1 articles | Viewed by 4206 | Submission Open
Keywords: scleral lenses; corneal irregularity; corneal disease; dry eye disease; irregular astigmatism; keratoconus; meibomian gland dysfunction; midday fogging
(This special issue belongs to the Section Ophthalmology)
Clinical and Surgical Updates on Bariatric Surgery submission deadline 20 Mar 2026 | 2 articles | Viewed by 3967 | Submission Open
Keywords: bariatric surgery; morbid obesity; sleeve gastrectomy; gastric bypass; surgical complications; diabetes remission; hypertension remission; hypercholesterolemia remission; GERD; de novo GERD
(This special issue belongs to the Section General Surgery)
Advanced Approaches in Hip and Knee Arthroplasty
edited by Filippo Randelli and
submission deadline 20 Mar 2026 | 4 articles | Viewed by 3940 | Submission Open
Keywords: hip; hip surgery; knee arthroplasty; knee surgery; hip and knee arthroplasty
(This special issue belongs to the Section Orthopedics)
Psoriasis in Focus: Current Research, Treatments, and Future Directions
edited by and Josep Riera-Monroig
submission deadline 20 Mar 2026 | 4 articles | Viewed by 3726 | Submission Open
Keywords: psoriasis; biologic therapies; immunopathogenesis; precision medicine; comorbidities in psoriasis; psoriatic arthritis; phototherapy; topical treatments; systemic therapies
(This special issue belongs to the Section Dermatology)
Clinical Advances in Kidney Transplantation submission deadline 20 Mar 2026 | 3 articles | Viewed by 3689 | Submission Open
Keywords: kidney transplantation; immunosuppression; graft survival; donor risk assessment; post-transplant management; rejection and tolerance; precision medicine in transplantation
(This special issue belongs to the Section Nephrology & Urology)
Advanced Therapy for Heart Failure and Other Combined Diseases
edited by Gori Mauro and Marco Marini
submission deadline 20 Mar 2026 | 5 articles | Viewed by 3623 | Submission Open
Keywords: heart failure with reduced and preserved ejection fraction; advanced heart failure; inotropes; acute heart failure; GDMT
(This special issue belongs to the Section Cardiology)
Coronary Artery Disease: Diagnosis, Treatment Challenges, and Emerging Therapy submission deadline 20 Mar 2026 | 2 articles | Viewed by 3167 | Submission Open
Keywords: coronary artery disease; percutaneous coronary intervention; cardiovascular disease; emerging therapies; treatment challenges; biomarkers; interventional cardiology
(This special issue belongs to the Section Cardiology)
Acute Pancreatitis and Its Complications: Current Diagnostics and Management
edited by
submission deadline 20 Mar 2026 | 3 articles | Viewed by 3068 | Submission Open
Keywords: acute pancreatitis; pancreas; pancreatic and peripancreatic necrosis; management; less invasive percutaneous radiological and endoscopic approaches
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Thoracic Surgery: State of the Art and Future Directions
edited by and
submission deadline 20 Mar 2026 | 5 articles | Viewed by 3055 | Submission Open
Keywords: thoracic surgery; lung surgery; lung cancer; rib fractures; lung disease; pectus excavatum
(This special issue belongs to the Section Respiratory Medicine)
Advances in Breast Reconstruction: New Technologies Improving Clinical Outcomes
edited by Luigi Antonio Valdatta
submission deadline 20 Mar 2026 | 3 articles | Viewed by 2746 | Submission Open
Keywords: breast reconstruction; acellular dermal matrix (ADM); artificial intelligence in surgery; advanced prostheses; breast malformation correction; 3D printing in reconstruction; robotic-assisted breast surgery; regenerative surgery
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Challenges and Opportunities in Prenatal Diagnosis
edited by Diana Massalska and
submission deadline 20 Mar 2026 | 2 articles | Viewed by 2675 | Submission Open
Keywords: prenatal diagnosis; genetic testing; fetal imaging; fetal therapy; personalized prenatal medicine
(This special issue belongs to the Section Obstetrics & Gynecology)
Recent Advances in the Prevention, Treatment, and Rehabilitation of Sports Injuries
edited by Nili Steinberg
submission deadline 20 Mar 2026 | 3 articles | Viewed by 2547 | Submission Open
Keywords: athletes; physical activity; sports; injuries; musculoskeletal; pain; rehabilitation; prevention; risk factors; functional abilities; muscle strength; joint range of motion (ROM); postural balance; ultrasonography maturation; adolescent
(This special issue belongs to the Section Sports Medicine)
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