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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Integrated Management of Cardiorenal Metabolic Syndrome: From Obesity to Chronic Kidney Disease submission deadline 20 Nov 2026 | Viewed by 260 | Submission Open
Keywords: cardiorenal metabolic syndrome; adipose tissue dysfunction; Insulin resistance; ectopic adiposity; cardiometabolic therapies
(This special issue belongs to the Section Endocrinology & Metabolism)
Advanced Technologies in Thoracic Anesthesia
edited by and
submission deadline 20 Nov 2026 | Viewed by 253 | Submission Open
Keywords: thoracic anesthesia; thoracic analgesia; preoperative management; enhanced recovery after surgery; thoracic Block; video-assisted thoracic surgery; robotic-assisted thoracic surgery; post-thoracotomy syndrome; airway device
(This special issue belongs to the Section Anesthesiology)
Recent Advances in the Diagnosis and Treatment of Breast Cancer submission deadline 20 Nov 2026 | Viewed by 252 | Submission Open
Keywords: breast cancer screening; diagnosis; surgery; radiotherapy; targeted treatment; neoadjuvant; quality of life
(This special issue belongs to the Section Oncology)
Advances in the Management of Cancer Pain
edited by Wojciech Leppert
submission deadline 20 Nov 2026 | Viewed by 247 | Submission Open
Keywords: analgesia; analgesics; cancer patients; chronic pain; pain in cancer patients; pain assessment; non-opioids; opioid analgesics; adjuvant analgesics; non-pharmacology methods of pain management
(This special issue belongs to the Section Epidemiology & Public Health)
Advances and Challenges in the Diagnosis and Treatment of Epilepsy
edited by
submission deadline 20 Nov 2026 | Viewed by 237 | Submission Open
Keywords: epilepsy; diagnosis; treatment; epilepsy surgery; clinical management
(This special issue belongs to the Section Clinical Neurology)
Clinical Advances in Psychotic Disorders: Precision Diagnosis and Personalized Treatment
edited by
submission deadline 20 Nov 2026 | Viewed by 236 | Submission Open
Keywords: psychotic disorders; early detection; precision diagnosis; personalized interventions; functional recovery; personal recovery; cognitive remediation; psychosocial treatment; recovery-oriented care; individualized care plans; digital mental health; telepsychiatry; artificial intelligence; virtual reality; predictive modeling
(This special issue belongs to the Section Mental Health)
Hip Fracture and Surgery: Clinical Updates and Challenges: 2nd Edition
edited by
submission deadline 20 Nov 2026 | Viewed by 233 | Submission Open
Keywords: antiosteoporosis medication; fracture liaison service; osteosynthesis; total hip arthroplasty; hemiarthroplasty
(This special issue belongs to the Section Orthopedics)
Fertility and Reproductive Health in Women
edited by
submission deadline 20 Nov 2026 | Viewed by 233 | Submission Open
Keywords: female fertility; reproductive health; infertility; assisted reproductive technology; reproductive endocrinology; ovarian reserve; reproductive aging; PCOS; endometriosis; fertility preservation
(This special issue belongs to the Section Obstetrics & Gynecology)
Colorectal Surgery: New Insights and Emerging Trends
edited by Marisa D. Santos, Nuno José Gomes Rama and Manuel Limbert
submission deadline 20 Nov 2026 | Viewed by 232 | Submission Open
Keywords: colorectal surgery; minimally invasive colorectal surgery; colorectal laparoscopic surgery; robotic-assisted colorectal surgery; precision colorectal surgery; enhanced recovery after surgery (ERAS); colorectal cancer; sphincter-preserving procedures; transanal surgery; pelvic floor surgery; personalized medicine; molecular profiling; biomarkers; artificial intelligence; image-guided surgery
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Resuscitation and Shock: Evolving Concepts and Clinical Strategies in Acute Care
edited by , Barbara P. Fyntanidou and
submission deadline 20 Nov 2026 | Viewed by 221 | Submission Open
Keywords: resuscitation; shock; emergency medicine; critical care; hemodynamic monitoring; sepsis; trauma; vasopressors; fluid therapy; car-diopulmonary resuscitation (CPR); preclinical studies; cardiac arrest
(This special issue belongs to the Section Emergency Medicine)
Robotic Surgery in Urology: Current Updates and Innovations
edited by Scott Leslie
submission deadline 20 Nov 2026 | Viewed by 219 | Submission Open
Keywords: robotics; oncology; prostatectomy; nephrectomy; bladder; transplant; minimally-invasive; nephroureterectomy; reconstructive; pyeloplasty; novel; laparoscopic
(This special issue belongs to the Section Nephrology & Urology)
Hepato-Pancreato-Biliary (HPB) Surgery: Precision and Outcomes
edited by Florian W. R. Vondran, Felix Oldhafer and Celia Villodre
submission deadline 20 Nov 2026 | Viewed by 210 | Submission Open
Keywords: hepato-pancreato-biliary surgery; liver surgery; minimally invasive surgery; robotic surgery; multidisciplinary treatment
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Advances in Adult Congenital Heart Disease: From Diagnosis to Long-Term Management
edited by Michael Huntgeburth
submission deadline 20 Nov 2026 | Viewed by 208 | Submission Open
Keywords: adult congenital heart disease; ACHD; long-term management; lifetime management; complications; arrhythmia; heart failure; endocarditis; pulmonary arterial hypertension; comorbidities; interventional treatment; surgical treatment; rehabilitation
(This special issue belongs to the Section Cardiology)
Innovations in Minimally Invasive and Personalized Urogynecology
edited by Günter Karl Noé and
submission deadline 20 Nov 2026 | Viewed by 207 | Submission Open
Keywords: urogynecology; pelvic floor disorders; minimally invasive reconstructive techniques; personalized and regenerative treatment strategies
(This special issue belongs to the Section Obstetrics & Gynecology)
Artificial Intelligence Applications in Urology
edited by , Rocco Papalia and Nicolas Carl
submission deadline 20 Nov 2026 | Viewed by 204 | Submission Open
Keywords: artificial intelligence; urology; machine learning; robotic surgery; digital pathology; predictive modeling
(This special issue belongs to the Section Nephrology & Urology)
New Technological Treatments and Methods in Neurorehabilitation
edited by
submission deadline 20 Nov 2026 | Viewed by 204 | Submission Open
Keywords: neurorehabilitation; robotics; virtual reality; exoskeleton; humankinesiology physiotherapy; stroke; parkinson's disease; gait; physical rehabilitation; rehabilitation interventions
(This special issue belongs to the Section Clinical Neurology)
Application of Magnetic Resonance Imaging in Cardiovascular Disease
edited by Dhrubajyoti Bandyopadhyay, Aneesh S. Dhorepatil and
submission deadline 20 Nov 2026 | Viewed by 201 | Submission Open
Keywords: cardiac MRI; tricuspid regurgitation; parametric imaging; 4D flow; WIP; flow reserve; artificial intelligence
(This special issue belongs to the Section Cardiovascular Medicine)
Cardiomyopathy: Advances in Clinical Diagnosis and Treatment
edited by and Ali Amr
submission deadline 20 Nov 2026 | Viewed by 198 | Submission Open
Keywords: cardiomyopathy; precision medicine; heart failure; cardiac imaging; genetics; myocardial biopsy; arrhythmias; targeted therapy
(This special issue belongs to the Section Cardiology)
New Challenges in Maternal–Fetal Medicine: 2nd Edition
edited by
submission deadline 20 Nov 2026 | Viewed by 197 | Submission Open
Keywords: thrombocytopenia in pregnancy; multiple pregnancies; placental abruption; DIC; sepsis; chorioamnionitis; cholestasis; postpartum hemorrhage; emergency cervical cerclage; problems in pregnancy and labor; pregnancy complications; spina bifida; fetal well-being evaluation
(This special issue belongs to the Section Obstetrics & Gynecology)
Current Concepts of Cardio–Renal Interactions
edited by
submission deadline 20 Nov 2026 | Viewed by 197 | Submission Open
Keywords: AKI; cardiorenal syndrome; contrast; biomarkers; renal insufficiency; cardio-nephrology; organ crosstalk
(This special issue belongs to the Section Cardiovascular Medicine)
Echocardiography: Clinical Updates and Perspectives
edited by Isabella Leo and Giulia La Vecchia
submission deadline 20 Nov 2026 | Viewed by 188 | Submission Open
Keywords: echocardiography; cardiovascular imaging; three-dimensional echocardiography; speckle-tracking echocardiog-raphy; myocardial strain imaging; contrast echocardiography; transesophageal echocardiography; valvular heart disease; structural heart disease; artificial intelligence
(This special issue belongs to the Section Cardiovascular Medicine)
Clinical Advancements in Radiology of Joint and Musculoskeletal Diseases
edited by
submission deadline 20 Nov 2026 | Viewed by 187 | Submission Open
Keywords: sports injuries; ligament injuries; ankle injury; prognostic imaging; individualized imaging; imaging algorithms; lower-extremity injury; clinical insights; knee injuries; groin and hip pain
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Optimizing Catheter Ablation for Atrial Fibrillation: Emerging Technologies and Clinical Progress
edited by Naiara Calvo
submission deadline 20 Nov 2026 | Viewed by 185 | Submission Open
Keywords: atrial fibrillation; pulsed field ablation; electroanatomical mapping; catheter ablation; electroporation; pulmonary veins
(This special issue belongs to the Section Cardiology)
Clinical Insights into Hearing Disorders: Towards Precision Diagnosis to Improve Outcomes and Quality of Life
edited by
submission deadline 20 Nov 2026 | Viewed by 180 | Submission Open
Keywords: hearing loss; hearing disorders; hearing aids; cochlear implant; hearing outcomes; auditory rehabilitation; quality of life
(This special issue belongs to the Section Otolaryngology)
Interventional Pulmonology: Advances and Future Directions—2nd Edition
edited by Martina Ferioli and Piero Candoli
submission deadline 20 Nov 2026 | Viewed by 168 | Submission Open
Keywords: interventional pulmonology; lung nodule; lung cancer; diagnosis; bronchoscopy; rigid bronchoscopy; airway stent; airway stenosis; mediastinal staging
(This special issue belongs to the Section Respiratory Medicine)
Practical Use of Technologies in Neuro–Oncological Surgery Across Different Settings
edited by Davide Milani
submission deadline 20 Nov 2026 | Viewed by 166 | Submission Open
Keywords: neuro-oncology; surgical technology; neuronavigation; intraoperative ultrasound; fluorescence-guided surgery; augmented reality; artificial intelligence; surgical innovation; clinical practice
(This special issue belongs to the Section Clinical Neurology)
Paediatric Thyroid Cancer: Diagnosis and Therapeutic Strategies
edited by Paul Z. Benitez-Aguirre, , Antoinette Anazodo and Theodore W. Laetsch
submission deadline 20 Nov 2026 | Viewed by 159 | Submission Open
Keywords: paediatric thyroid cancer; differentiated thyroid carcinoma; molecular diagnostics; gene fusions (RET, NTRK, BRAF); targeted therapy; neoadjuvant therapy; adjuvant therapy; radioactive iodine (131I); dosimetry; tumour response and shrinkage; multidisciplinary models of care; survivorship and late effects
(This special issue belongs to the Section Endocrinology & Metabolism)
From the Silk Road of Endoscopy to the Roads to Rome V of Neurogastroenterology: Dual Pathways Shaping Modern Gastroenterology
edited by Stefano Kayali
submission deadline 20 Nov 2026 | Viewed by 156 | Submission Open
Keywords: endoscopy; advanced imaging; minimally invasive therapies; gastrointestinal diagnostics; gut–brain interaction; DGBI; Rome V; neurogastroenterology; clinical innovation; GI physiology
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Advances in Immune-Mediated Inflammatory Diseases
edited by
submission deadline 20 Nov 2026 | Viewed by 143 | Submission Open
Keywords: pediatric immune-mediated inflammatory diseases (IMIDs); juvenile idiopathic arthritis; systemic lupus erythematosus; pediatric vasculitis; IgA nephropathy; complement-mediated kidney diseases; inflammatory bowel diseases; organ-specific inflammation; biomarkers for disease activity and diagnosis; biologic and targeted therapies; early recognition and diagnostic strategies; multidisciplinary care and integrated management
(This special issue belongs to the Section Immunology & Rheumatology)
Advances in Fetal Medicine: AI Integration and Advancements
edited by Christos Anthoulakis
submission deadline 20 Nov 2026 | Viewed by 131 | Submission Open
Keywords: fetal medicine; artificial intelligence; obstetrical complications; fetal syndromes; genetic conditions
(This special issue belongs to the Section Obstetrics & Gynecology)
Sexually Transmitted Infections: Persistent Challenges and Innovative Solutions
edited by Thomas E. Dobbs and
submission deadline 20 Nov 2026 | Viewed by 131 | Submission Open
Keywords: sexually transmitted infections (STIs); sexual and reproductive health; STI prevention and control; public health interventions; prevention advancements in sexual health; stigma and sexual health
(This special issue belongs to the Section Infectious Diseases)
Interventional Pain Management: Current Evidence and Innovative Advances
edited by Jamal Hasoon
submission deadline 24 Nov 2026 | 3 articles | Viewed by 2550 | Submission Open
Keywords: interventional pain management; chronic pain; image-guided procedures; injection techniques; neuromodulation; peripheral nerve blocks; radiofrequency ablation; minimally invasive spine interventions; artificial intelligence in medicine; quality improvement; clinical outcomes
(This special issue belongs to the Section Anesthesiology)
The Management of Chronic Cholestatic Diseases submission deadline 24 Nov 2026 | Viewed by 233 | Submission Open
Keywords: chronic cholestatic liver diseases; cholestasis; primary biliary cholangitis; primary sclerosing cholangitis; cholangiocar-cinoma
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Ventilation in Critical Care Medicine: 2nd Edition
edited by Gianluca Zani
submission deadline 25 Nov 2026 | 5 articles | Viewed by 33071 | Submission Open
Keywords: invasive ventilation; non-invasive ventilation; acute respiratory failure; best PEEP; respiratory weaning; respiratory mechanics; ventilation and perfusion; personalized ventilation
(This special issue belongs to the Section Intensive Care)
Advances in the Diagnosis and Treatment of Glaucoma
edited by
submission deadline 25 Nov 2026 | 12 articles | Viewed by 19403 | Submission Open
Keywords: OCT; glaucoma; MIGS; neuroprotection; drug delivery systems; artificial intelligence; pharmacologic agents; per-sonalized medicine
(This special issue belongs to the Section Ophthalmology)
Current Clinical Advances in Urinary Incontinence
edited by Adolf Lukanovic, David Lukanović and Mija Blaganje
submission deadline 25 Nov 2026 | 4 articles | Viewed by 4919 | Submission Open
Keywords: female urinary incontinence; stress urinary incontinence; overactive bladder; diagnosis; prevention; conservative treatment; minimally invasive treatment; surgery; mid-urethral sling; new approach; energy-based devices
(This special issue belongs to the Section Nephrology & Urology)
Diabetic Foot: Emerging Prevention Strategies and Epidemiology submission deadline 25 Nov 2026 | 3 articles | Viewed by 4753 | Submission Open
Keywords: diabetic foot; foot clinics; epidemiology; prevention; screening; amputation; podiatry
(This special issue belongs to the Section Endocrinology & Metabolism)
Clinical Advances in Gastrointestinal Endoscopy
edited by and Željko Puljiz
submission deadline 25 Nov 2026 | 4 articles | Viewed by 4179 | Submission Open
Keywords: endoscopy; polyps; EMR; ESD; POEM; balloon dilatation; coagulation; imaging; AI imaging
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Approaches and Challenges in Oral Rehabilitation
edited by and Takayuki Kosaka
submission deadline 25 Nov 2026 | 3 articles | Viewed by 3236 | Submission Open
Keywords: oral rehabilitation; oral health; systemic health; dental innovation; neuroplasticity
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Physical Activity, Exercise and Health: Implications for Clinical Practice submission deadline 25 Nov 2026 | 1 articles | Viewed by 2747 | Submission Open
Keywords: physical activity; exercise prescription; clinical practice; chronic disease management; rehabilitation; preventive medicine; personalized medicine; sex and gender differences
(This special issue belongs to the Section Sports Medicine)
Epilepsy and Cerebrovascular Disorders
edited by
submission deadline 25 Nov 2026 | 2 articles | Viewed by 2260 | Submission Open
Keywords: epilepsy; cerebrovascular disorders; stroke; post-stroke epilepsy; neuroinflammation; neuroimaging; electroenceph-alography; biomarkers; antiepileptic treatment; translational neuroscience
(This special issue belongs to the Section Clinical Neurology)
Clinical Advances in Personalized Psychiatry
edited by
submission deadline 25 Nov 2026 | 3 articles | Viewed by 2218 | Submission Open
Keywords: personalized psychiatry; biomarkers; predictive modeling; precision diagnosis; neuroimaging biomarkers; effective treatments
(This special issue belongs to the Section Mental Health)
Recent Advances in Minimally Invasive Surgery and Endoscopy of Gynecologic Oncology
edited by Hiroaki Komatsu, and Tsukasa Baba
submission deadline 25 Nov 2026 | 3 articles | Viewed by 1839 | Submission Open
Keywords: cervical cancer; ovarian cancer; gynecologic cancer; robotic surgery; minimally invasive surgery
(This special issue belongs to the Section Obstetrics & Gynecology)
Hematological Neoplasms: Diagnosis, Treatment, and Management in the Department of Veterans Affairs
edited by Solomon A. Graf, Daphne R. Friedman and Suman Kambhampati
submission deadline 25 Nov 2026 | 3 articles | Viewed by 1836 | Submission Open
Keywords: hematologic malignancies; veterans affairs; therapeutics; biomarkers; rural medicine; integrated healthcare; demographics; exposures; trials in progress; treatment pathways
(This special issue belongs to the Section Hematology)
The Current Concept and Emerging Treatments of Coronary Artery Disease (CAD)
edited by Simone Fezzi and Roberto Scarsini
submission deadline 25 Nov 2026 | 2 articles | Viewed by 1645 | Submission Open
Keywords: coronary physiology; intracoronary imaging; imaging-derived computational physiology; drug-coated balloon and bioresorbable scaffolds; virtual PCI; artificial intelligence
(This special issue belongs to the Section Cardiovascular Medicine)
Advances in the Clinical Management of Diabetic Retinopathy
edited by
submission deadline 25 Nov 2026 | 2 articles | Viewed by 1368 | Submission Open
Keywords: retinal imaging; clinical outcomes; optical coherence tomography (OCT); vitrectomy; blood flow
(This special issue belongs to the Section Ophthalmology)
Novel Approaches and Techniques in Neurosurgery
edited by and
submission deadline 25 Nov 2026 | 3 articles | Viewed by 1330 | Submission Open
Keywords: neurosurgery; minimally invasive neurosurgery; endoscopic neurosurgery; spine surgery; surgical robotics; neu-ro-navigation; intraoperative imaging; artificial intelligence; neuro-oncology surgery; skull base surgery; im-age-guided surgery
(This special issue belongs to the Section Clinical Neurology)
Advances in Kidney Transplantation: 2nd Edition
edited by Pedro Ruiz-Esteban, Domingo Hernández-Marrero and Verónica López-Jiménez
submission deadline 25 Nov 2026 | 2 articles | Viewed by 1302 | Submission Open
Keywords: kidney transplant; acute rejection; biomarkers; artificial intelligence; post-transplant complications; graft survival
(This special issue belongs to the Section Nephrology & Urology)
Clinical Advances and Challenges in Vascular and Endovascular Medicine: 2nd Edition
edited by
submission deadline 25 Nov 2026 | 2 articles | Viewed by 1100 | Submission Open
Keywords: vascular and endovascular medicine; minimally invasive cardiovascular surgery; vascular diseases; endovascular technologies
(This special issue belongs to the Section Vascular Medicine)
Surgical Innovation and Clinical Outcomes in Plastic and Reconstructive Surgery
edited by Pari Naz Mohanna and Ayush Kapila
submission deadline 25 Nov 2026 | 1 articles | Viewed by 1087 | Submission Open
Keywords: plastic and reconstructive surgery; microsurgery; breast reconstruction; surgical innovation; novel flap techniques
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
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