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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Updates in Lung Ultrasound
edited by
submission deadline 20 Nov 2025 | 1 articles | Viewed by 1705 | Submission Open
Keywords: lung ultrasound; intensive care; imaging; ARDS; POCUS
(This special issue belongs to the Section Respiratory Medicine)
Clinical Perspectives in Reconstructive Urethral Surgery
edited by Krishnan Venkatesan
submission deadline 20 Nov 2025 | 2 articles | Viewed by 1688 | Submission Open
Keywords: urethral reconstruction; urethroplasty; urethral stricture; bladder neck stenosis; urinary fistula
(This special issue belongs to the Section Nephrology & Urology)
Future Directions in Imaging-Guided Glaucoma Diagnosis and Therapy
edited by
submission deadline 20 Nov 2025 | 1 articles | Viewed by 1237 | Submission Open
Keywords: optical coherence tomography; optical coherence tomography angiography; visual field testing; glaucoma surgery; MIGS; structure– function relationship in glaucoma
(This special issue belongs to the Section Ophthalmology)
Latest Advances in Glaucoma, Cataract and Refractive Surgery: Expert Views, 2nd Edition submission deadline 20 Nov 2025 | 1 articles | Viewed by 1014 | Submission Open
Keywords: refractive surgery; glaucoma; cataract; intraocular lenses; diagnostic imaging
(This special issue belongs to the Section Ophthalmology)
State of the Art in Neuromodulation or Spinal Cord Stimulation Therapy
edited by Marco Mercieri
submission deadline 20 Nov 2025 | 1 articles | Viewed by 1010 | Submission Open
Keywords: neuromodulation; spinal cord stimulation; chronic pain management; stimulation waveforms; long-term efficacy; loss of efficacy; outcome prediction; opioid-sparing techniques; neurostimulation mechanisms; psychological predictors; therapeutic targets
(This special issue belongs to the Section Clinical Neurology)
Prostate Cancer: Diagnosis, Clinical Management and Prognosis
edited by Giovanni Muto
submission deadline 20 Nov 2025 | 3 articles | Viewed by 968 | Submission Open
Keywords: prostate cancer; diagnosis; clinical management; prognosis; treatments
(This special issue belongs to the Section Nephrology & Urology)
Challenges and Opportunities in Geriatric Nephrology and Urology
edited by Giulio Romano
submission deadline 20 Nov 2025 | 1 articles | Viewed by 863 | Submission Open
Keywords: kidney disease; elderly patient; epidemiology; pharmacological therapy; lifestyle diet
(This special issue belongs to the Section Nephrology & Urology)
Advances in Retinal Diseases—Mechanisms, Diagnostics, and Emerging Therapies
edited by
submission deadline 20 Nov 2025 | 2 articles | Viewed by 848 | Submission Open
Keywords: inherited retinal diseases; age-related macular degeneration; diabetic retinopathy; multimodal retinal imaging; treatment
(This special issue belongs to the Section Ophthalmology)
State-of-the-Art Research on Thoracic Surgery submission deadline 20 Nov 2025 | 1 articles | Viewed by 550 | Submission Open
Keywords: 3D imaging; surgical process optimization; robotic surgery; immunotherapy and targeted therapy; novel cancer detection methods; personalized treatment
(This special issue belongs to the Section General Surgery)
Current Status and Future Directions in Cardiac Surgery
edited by Marie-Elisabeth Stelzmüller and Randolph H.L. Wong
submission deadline 20 Nov 2025 | Viewed by 454 | Submission Open
Keywords: innovations; AI; minimally invasive; endoscopic; novel technologies in electrophysiology; hybrid procedures; inno-vative approaches in cardiac surgery and patient care
(This special issue belongs to the Section Cardiology)
Aortic Valve Implantation: Recent Advances and Future Prospects
edited by Suvitesh Luthra and Richard Jabbour
submission deadline 20 Nov 2025 | Viewed by 396 | Submission Open
Keywords: aortic valve replacement; aortic stenosis; paravalvular leak; coronary and structural interventional cardiology; percutaneous coronary artery interventions
(This special issue belongs to the Section Cardiology)
New Advances in Uterus and Ovarian Transplantation: 2nd Edition submission deadline 20 Nov 2025 | 1 articles | Viewed by 394 | Submission Open
Keywords: uterus transplantation; gynaecological surgery; endometriosis; IVF; fibroids; reproductive medicine; laparoscopic surgery; assisted reproductive technology; reproductive endocrinology
(This special issue belongs to the Section Obstetrics & Gynecology)
Arthritis: From Diagnosis to Treatment
edited by Andrea Di Matteo and
submission deadline 20 Nov 2025 | 1 articles | Viewed by 367 | Submission Open
Keywords: rheumatoid arthritis; psoriatic arthritis; imaging; ultrasound; DMARDs; differential diagnosis; difficult to treat rheumatoid arthritis; prevention
(This special issue belongs to the Section Immunology)
Challenges and Future Trends in Bariatric Surgery
edited by Maurizio L. de Luca and Amanda Belluzzi
submission deadline 20 Nov 2025 | Viewed by 339 | Submission Open
Keywords: metabolic and bariatric surgery; SADI-S; LSG; RYGB; SASI; OAGB; complications after MBS; long-term outcomes; malnutrition
(This special issue belongs to the Section General Surgery)
Cardiac Imaging in the Diagnosis and Management of Heart Failure
edited by Mahi Lakshmi Ashwath and Allen S. Anderson
submission deadline 20 Nov 2025 | Viewed by 276 | Submission Open
Keywords: echocardiography; cardiac MRI; myocardial viability; tissue characterization; ischemic and non-ischemic cardiomyopathy; HFpEF; myocardial strain
(This special issue belongs to the Section Cardiology)
Clinical Therapeutic and Management Strategies of Epilepsy—Social and Neuropsychological Aspects
edited by
submission deadline 20 Nov 2025 | Viewed by 239 | Submission Open
Keywords: quality of life (QOL); cognition; behavior; stigma; seizure severity; interictal epileptiform discharge (IED); social
(This special issue belongs to the Section Clinical Neurology)
Challenges in Fertility Preservation
edited by and Guido Ambrosini
submission deadline 20 Nov 2025 | Viewed by 237 | Submission Open
Keywords: fertility preservation; oocytes cryopreservation; embryo cryopreservation; ovarian tissue transplantation; gonadotoxic therapy
(This special issue belongs to the Section Reproductive Medicine & Andrology)
Research Progress in Pediatric Endocrinology
edited by
submission deadline 20 Nov 2025 | Viewed by 145 | Submission Open
Keywords: pediatric endocrinology; rare endocrine disorders; precision medicine; congenital adrenal hyperplasia (CAH); short stature genetics; severe childhood obesity; glp-1 receptor agonists; endocrine disruptors; artificial intelligence (AI) in endocrinology; newborn screening
(This special issue belongs to the Section Clinical Pediatrics)
Minimally Invasive Techniques in Digestive Pathologies
edited by
submission deadline 20 Nov 2025 | Viewed by 128 | Submission Open
Keywords: minimally invasive surgery; laparoscopic techniques; robotic surgery; endoscopic interventions; hybrid surgical approaches; digestive oncology; AI in surgery; surgical innovation; gastrointestinal disorders
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Advances in Pulmonary Hypertension and Idiopathic Pulmonary Fibrosis
edited by
submission deadline 20 Nov 2025 | Viewed by 117 | Submission Open
Keywords: pulmonary hypertension; interstitial lung disease; idiopathic pulmonary fibrosis; heart failure; mitral valve disease
(This special issue belongs to the Section Respiratory Medicine)
Skin Wound Healing: Clinical Updates and Perspectives
edited by and Norbert Kiss
submission deadline 20 Nov 2025 | Viewed by 117 | Submission Open
Keywords: dermatology; wound care; diagnosis; biomaterials; negative pressure wound therapy
(This special issue belongs to the Section Dermatology)
Acute Ischemic Stroke Management Strategies
edited by
submission deadline 20 Nov 2025 | Viewed by 108 | Submission Open
Keywords: mechanical thrombectomy; leptomeningeal collateral circulation; neuroprotection; reperfusion injury; ischemic penumbra
(This special issue belongs to the Section Clinical Neurology)
New Therapies for Diabetic Foot Ulcer Management submission deadline 20 Nov 2025 | Viewed by 101 | Submission Open
Keywords: diabetic foot disease; diabetic foot ulcers; wound healing; biomarkers; telemedicine; artificial intelligence; preven-tive strategies; advanced therapies; amputation prevention; diabetes complications; novel treatments
(This special issue belongs to the Section Endocrinology & Metabolism)
Diagnosis and Treatment of Ocular Surface Diseases submission deadline 20 Nov 2025 | Viewed by 100 | Submission Open
Keywords: dry eye disease; ocular surface; anterior segment imaging; biomarkers; artificial intelligence; diagnostic tools; novel therapeutic agents; anterior eye care
(This special issue belongs to the Section Ophthalmology)
Low Back Pain: Clinical Treatment and Management submission deadline 20 Nov 2025 | Viewed by 96 | Submission Open
Keywords: exercise; rehabilitation; weight loss; telerehabilitation; pain; physical therapy; treatment; conservative treatment; intervertebral disk displacement; low back pain; sciatica
(This special issue belongs to the Section Clinical Neurology)
Cardiac MRI: Current Techniques and Future Directions
edited by
submission deadline 20 Nov 2025 | Viewed by 91 | Submission Open
Keywords: cardiac magnetic resonance imaging; technology; sequences; applications; acute coronary syndrome; intravascular imaging; CT-scanner
(This special issue belongs to the Section Cardiology)
Clinical Research in Management of Corneal Diseases
edited by Massimo Busin and Angeli Christy Yu
submission deadline 20 Nov 2025 | Viewed by 88 | Submission Open
Keywords: corneal surgery; corneal transplant; lamellar keratoplasty; deep anterior lamellar keratoplasty; descemet membrane endothelial keratoplasty; descemet stripping automated endothelial keratoplasty; corneal neurotization
(This special issue belongs to the Section Ophthalmology)
High-Risk Neuroblastoma and Rhabdoid Tumors: New Clinical Insights and Challenges (Second Edition)
edited by and Johannes Hubertus Schulte
submission deadline 20 Nov 2025 | Viewed by 76 | Submission Open
Keywords: neuroblastoma; rhabdoid tumor; autologous stem cell transplantation; allogeneic stem cell transplantation immunotherapy; anti-GD2 antibody; targeted therapy; CAR T-cells
(This special issue belongs to the Section Oncology)
Targeted Diagnosis and Treatment of Shoulder and Elbow Disease: 2nd Edition submission deadline 20 Nov 2025 | Viewed by 75 | Submission Open
Keywords: anterolateral deltoid split; joint pain; axillary nerve injury; rotator cuff injuries; shoulder arthroplasty; shoulder impingement syndrome; proximal humeral fracture; rehabilitation; exercise; physiotherapy; rehabilitative relapses
(This special issue belongs to the Section Orthopedics)
Diagnosis and Treatment of Scoliosis and Spinal Deformity
edited by Anna Rienmueller and Kenny Yat Hong Kwan
submission deadline 20 Nov 2025 | Viewed by 69 | Submission Open
Keywords: scoliosis; spinal deformity; adolescent idiopathic scoliosis (AIS); early onset scoliosis (EOS); neuromuscular scoliosis; adult spinal deformity (ASD); operative treatment; spinal fusion; neuromonitoring in scoliosis and deformity surgery; perioperative risk factors; conservative treatment; bracing therapy; physiotherapy scoliosis-specific exercises (PSSE) and Schroth therapy; spinal biomechanics; scoliosis imaging; low-dose radiation imaging; artificial intelligence in scoliosis; 3D modelling in spinal deformity including surgical planning; predictive modelling in scoliosis progression; biomechanics of spinal curvature; growth modulation; patient-reported outcomes in scoliosis treatment
(This special issue belongs to the Section Orthopedics)
Novel Approaches in Cataract and Refractive Surgery
edited by Stephen T. Armenti
submission deadline 20 Nov 2025 | Viewed by 68 | Submission Open
Keywords: cataract surgery; complex cataract surgery; secondary intraocular lens surgery; refractive surgery (LASIK; PRK; SMILE); astigmatism correction; multifocal intraocular lenses; femtosecond laser; dropless cataract surgery
(This special issue belongs to the Section Ophthalmology)
Clinical Insights in Maternal–Fetal Medicine
edited by Moti Gulersen
submission deadline 20 Nov 2025 | Viewed by 68 | Submission Open
Keywords: preterm birth; antenatal corticosteroids; preeclampsia; ultrasound; fetal growth; congenital anomalies; infection; maternal morbidity; diabetes; multiple gestation
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Procedures for Diagnosis and Treatment of Cardiovascular Diseases
edited by Ahmad Jabri, Mohammad Alqarqaz, Qais Radaideh and Ahmad Al-Abdouh
submission deadline 20 Nov 2025 | Viewed by 65 | Submission Open
Keywords: cardiovascular disease; diagnostic imaging; minimally invasive procedures; precision medicine; artificial intelligence; interventional cardiology; surgical innovations; patient outcomes; preventive cardiology
(This special issue belongs to the Section Cardiovascular Medicine)
Effect of Long-Term Insomnia on Mental Health—2nd Edition submission deadline 21 Nov 2025 | 1 articles | Viewed by 624 | Submission Open
Keywords: anxiety; alcohol and substance use disorders; behavioral addiction; burnout; cognitive dysfunction; depression; eating disorders; gaming addiction; problematic internet/social media use; insomnia; long-term insomnia; mood disorders; post-traumatic stress disorder; stress
(This special issue belongs to the Section Mental Health)
Research Advances in Coagulation Disorders
edited by Alberto Maino
submission deadline 21 Nov 2025 | Viewed by 89 | Submission Open
Keywords: coagulation; bleeding disorders; thrombosis; hemophilia; clotting disorders; hematology
(This special issue belongs to the Section Hematology)
Clinical Features and Management of Psychosis
edited by , and Michael Hadjulis
submission deadline 23 Nov 2025 | 1 articles | Viewed by 405 | Submission Open
Keywords: psychosis; clinical features of psychosis; diagnosis of psychosis; schizophrenia; psychotic depression; affective disorder with psychotic features; psychosis in substance use disorders; psychosis in neurological disorders; psychosis in medical conditions; management of psychosis; treatment of psychosis
(This special issue belongs to the Section Mental Health)
Clinical Management of Type 1 Diabetes
edited by Carmen Quirós
submission deadline 25 Nov 2025 | 6 articles | Viewed by 15706 | Submission Open
Keywords: type 1 diabetes; continuous glucose monitoring; hybrid closed loop; hypoglycemia; physical activity; new onset type 1 diabetes; pre-stage 3 type 1 diabetes; smart insulin pens
(This special issue belongs to the Section Endocrinology & Metabolism)
Glomerulonephritis: Current Diagnosis, Treatment and Future Options
edited by Ana I. Ávila and
submission deadline 25 Nov 2025 | 3 articles | Viewed by 8362 | Submission Open
Keywords: glomerulonephritis; diagnosis; management; drug therapies; treatment
(This special issue belongs to the Section Nephrology & Urology)
The “Orthogeriatric Fracture Syndrome”—Issues and Perspectives submission deadline 25 Nov 2025 | 6 articles | Viewed by 6766 | Submission Open
Keywords: geriatric trauma; fragility fracture; orthogeriatric; co-management; assessment; integrated care; osteoporosis; sarcopenia; frailty; gait disturbance; fall; rehabilitation; prehabilitation; prevention; ehealth; digitalization
(This special issue belongs to the Section Orthopedics)
Perinatal Mental Health Management submission deadline 25 Nov 2025 | 3 articles | Viewed by 6578 | Submission Open
Keywords: perinatal mental health; child mental health; problem behavior; cognitive development therapy; hyperactivity
(This special issue belongs to the Section Mental Health)
Neurovascular Diseases: Clinical Advances and Challenges
edited by , Silky Chotai, Alessandro Di Rienzo and Joham Choque-Velasquez
submission deadline 25 Nov 2025 | 5 articles | Viewed by 5117 | Submission Open
Keywords: neurovascular diseases; ischemic stroke; hemorrhagic stroke; aneurysms; vascular malformations; diagnostic imaging; minimally invasive approaches; surgical techniques; endovascular interventions; treatment algorithms
(This special issue belongs to the Section Clinical Neurology)
Cardiothoracic Surgery and Enhanced Recovery: Recent Advances and Perspectives
edited by Edris A.F. Mahtab
submission deadline 25 Nov 2025 | 3 articles | Viewed by 4456 | Submission Open
Keywords: coronary artery bypass surgery; valve repair/replacement; minimally invasive cardiac procedures; aortic dissection repair; thoracic aortic aneurysm surgery; lung transplantation; ventricular assist devices; esophagectomy; lung surgery; heart transplantation; use of XR and AI in Enhanced recovery
(This special issue belongs to the Section General Surgery)
Gynecological Cancers—Surgical Management, Prognosis, and Quality of Life: 2nd Edition submission deadline 25 Nov 2025 | 5 articles | Viewed by 3972 | Submission Open
Keywords: gynecological cancers; endometrial cancer; ovarian cancer; cervical cancer; vulvar cancer; vaginal cancer; breast cancer; surgery; radiotherapy; systemic treatment; quality of life
(This special issue belongs to the Section Obstetrics & Gynecology)
Challenges in Diagnosis and Treatment of Gynecological Malignancies in Young Adults
edited by , Dimitrios Haidopoulos and
submission deadline 25 Nov 2025 | 4 articles | Viewed by 3956 | Submission Open
Keywords: gynecological cancers; young adults; young women; fertility; personalized care
(This special issue belongs to the Section Obstetrics & Gynecology)
Endometriosis: Clinical Challenges and Prognosis submission deadline 25 Nov 2025 | 4 articles | Viewed by 3778 | Submission Open
Keywords: endometriosis; therapy; rehabilitation; psychology; diagnostics; ultrasound imaging; metabolomics; prognosis
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Diagnosis and Management of Vestibular Disorders
edited by Sinisa Maslovara, Mario Habek and
submission deadline 25 Nov 2025 | 5 articles | Viewed by 3337 | Submission Open
Keywords: vertigo; dizziness; epidemiology; genetics; diagnostics; management
(This special issue belongs to the Section Otolaryngology)
Recent Advances in Spine Tumor Diagnosis and Treatment
edited by Jae Hwan Cho
submission deadline 25 Nov 2025 | 5 articles | Viewed by 3274 | Submission Open
Keywords: spine tumor; spinal metastasis; pathologic fracture; cord compression; separation surgery; radiotherapy; interdisciplinary collaboration; surgeon’ s role; medical oncologist; radiologic oncologist; psychological aspects; pain management; innovative approaches; patient outcomes; diagnostic advancements
(This special issue belongs to the Section Clinical Neurology)
Chronic Lung Conditions: Integrative Approaches to Long-Term Care submission deadline 25 Nov 2025 | 3 articles | Viewed by 3264 | Submission Open
Keywords: chronic lung conditions: chronic non-infectious lung disease and post-respiratory infectious syndromes; including TB sequelae; TB MDR; post-COVID-19; and bronchiectasis; long-term care; integrative approach; multidisciplinary; multimorbidity; outcomes
(This special issue belongs to the Section Respiratory Medicine)
Cystic Fibrosis: Novel Strategies of Diagnosis and Treatments
edited by and
submission deadline 25 Nov 2025 | 5 articles | Viewed by 3129 | Submission Open
Keywords: cystic fibrosis; CFTR modulators; stop mutations; gene therapy; mRNA therapy; novel therapies; rare pathogens
(This special issue belongs to the Section Respiratory Medicine)
A Multi-Faceted Approach to Urinary Incontinence and Other Pelvic Floor Dysfunction—from Prevention to Therapy submission deadline 25 Nov 2025 | 2 articles | Viewed by 3127 | Submission Open
Keywords: urinary incontinence; pelvic floor dysfunction; urinary and fecal incontinence; pelvic organs prolapse; pelvic pain; pelvic floor disorders
(This special issue belongs to the Section Nephrology & Urology)
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