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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Gastroparesis: Emerging Insights and Endoscopic Therapeutic Strategies

edited by Sabrina Testoni

submission deadline 20 Jul 2026 | Viewed by 38 | Submission Open

Keywords: gastroparesis; gastric dismotility; gastric emptying; gastric per-oral miotomy; pyloromyotomy; gastric electric stim-ulation; botulinum toxin

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Advances in Clinical Practice and Personalized Approaches in Cardiovascular Disease—2nd Edition

edited by Joseph B. Selvanayagam and

Sivabaskari Pasupathy

submission deadline 20 Jul 2026 | Viewed by 38 | Submission Open

Keywords: personalized medicine; cardiovascular innovations; cardiac imaging; risk assessment; multimodal imaging; therapeutic strategies; data-driven decision making; clinical outcomes; translational research

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Research on Robot-Assisted Thoracic Surgery and Lung Surgery

edited by Marco Scarci

submission deadline 20 Jul 2026 | Viewed by 37 | Submission Open

Keywords: robot-assisted thoracic surgery; robotic lung surgery; minimally invasive surgery; lobectomy; segmentectomy; thoracic oncology; surgical outcomes; learning curve; clinical research; robotic technology

(This special issue belongs to the Section General Surgery)

Current Measures for Diagnosis, Monitoring, and Outcome Assessment in Orthopedics, Traumatology, and Hand Surgery, 2nd Edition

edited by

Paweł Reichert

and

Piotr Morasiewicz

submission deadline 20 Jul 2026 | Viewed by 35 | Submission Open

Keywords: clinical evaluation; hand surgery; orthopaedics; performance-based measures; physical examination; reliability; traumatology

(This special issue belongs to the Section Orthopedics)

Challenges and Solutions in Geriatric Fracture

edited by Detlef Van der Velde and

Henk Jan Schuijt

submission deadline 20 Jul 2026 | Viewed by 35 | Submission Open

Keywords: geriatric; fracture; frailty; hip fracture; comorbidity; perioperative optimization; orthogeriatrics; rehabilitation; shared decision-making; postoperative outcomes; mortality and morbidity; functional recovery; multidisciplinary care; quality of life; recovery; mobility; palliative care

(This special issue belongs to the Section Geriatric Medicine)

Corneal Diseases: Clinical Perspectives from Diagnosis to Treatment

edited by Davide Romano

submission deadline 20 Jul 2026 | Viewed by 35 | Submission Open

Keywords: cornea; keratoplasty; keratitis; keratoconus; clinical perspectives

(This special issue belongs to the Section Ophthalmology)

Clinical Management of Patients Before and After Kidney Transplantation

edited by

Izabela Zakrocka

submission deadline 20 Jul 2026 | Viewed by 28 | Submission Open

Keywords: chronic kidney disease; kidney function; kidney replacement therapy; kidney transplantation; kidney graft survival; post-transplant complications

(This special issue belongs to the Section Nephrology & Urology)

Head and Neck Surgery: Immunotherapy’s Role in Shaping Treatment Paradigms

edited by

Mark S. Swanson

submission deadline 20 Jul 2026 | Viewed by 25 | Submission Open

Keywords: head and neck surgery; otorhinolaryngology; ENT; transoral surgery; laryngeal surgery; laryngeal carcinoma; sinonasal surgery; oral cancer; oropharyngeal cancer; laryngectomy; immunotherapy; head and neck cancer; cutaneous cancer

(This special issue belongs to the Section Otolaryngology)

Echocardiography in Clinical Cardiac Imaging: Advances and Emerging Applications

edited by

Marina Leitman

submission deadline 20 Jul 2026 | Viewed by 22 | Submission Open

Keywords: echocardiography; cardiac Imaging; speckle-tracking echocardiography; artificial intelligence; myocardial function; valvular heart disease; precision cardiology

(This special issue belongs to the Section Cardiology)

Macular Diseases: From Diagnosis to Treatment

edited by

Gabriella De Salvo

submission deadline 22 Jul 2026 | 1 articles | Viewed by 647 | Submission Open

Keywords: age-related macular degeneration; retinal vascular diseases; intraocular tumours; retinal imaging; OCT; OCT angiography; anti-VEGF; laser therapy; macular surgery; gene therapy; biomarkers; progression; intravitreal injections; biomarkers

(This special issue belongs to the Section Ophthalmology)

Psychological Affliction in Pregnancy, Delivery and Postpartum Period: A Multidisciplinary Approach

edited by

Beata Pięta

and

Edyta Barnas̈

submission deadline 24 Jul 2026 | Viewed by 137 | Submission Open

Keywords: maternal mental health; pregnancy; postpartum depression; perinatal anxiety; midwifery; multidisciplinary care

(This special issue belongs to the Section Mental Health)

Clinical Strategies for Preventing Healthcare-Associated Infections

edited by

Monica Marilena Țânțu

Rogozea Liliana Marcela

and

Corneliu Ovidiu Vrancianu

submission deadline 24 Jul 2026 | Viewed by 81 | Submission Open

Keywords: healthcare-associated infections; multidrug resistance; prevention; screening scales; polymicrobial infections; oppor-tunistic infections; sepsis

(This special issue belongs to the Section Infectious Diseases)

Recent Clinical Advances in Pelvic Organ Prolapse

edited by José Antonio García-Mejido and José Antonio Sainz-Bueno

submission deadline 24 Jul 2026 | Viewed by 76 | Submission Open

Keywords: pelvic organ prolapse; pelvic floor dysfunction; urogynecology; pelvic reconstructive surgery; pathophysiology of POP; surgical techniques; conservative management; patient-reported outcomes; biomaterials in pelvic surgery; levator ani muscle

(This special issue belongs to the Section Obstetrics & Gynecology)

Rewriting Metastatic Colorectal Cancer Management: Innovative Frontiers in Clinical Diagnosis and Personalized Oncology

edited by

Maria Maddalena Laterza

submission deadline 24 Jul 2026 | Viewed by 61 | Submission Open

Keywords: molecular profiling; liquid biopsy; targeted therapy; immunotherapy; biomarkers treatment; sequencing; tumor heterogeneity; personalized medicine

(This special issue belongs to the Section Oncology)

Clinical Advances in Spinal Neurosurgery

edited by Jang-Won Yoon

submission deadline 25 Jul 2026 | 2 articles | Viewed by 2514 | Submission Open

Keywords: minimally invasive spine surgery; lateral lumbar interbody fusion; endoscopic spine surgery; patient-reported out-comes; functional assessment; perioperative care; surgical decision-making

(This special issue belongs to the Section Clinical Neurology)

Clinical Advances in Hysteroscopic Technology for Gynecological Diseases

edited by Aya Mohr-Sasson and Raanan Meyer

submission deadline 25 Jul 2026 | Viewed by 383 | Submission Open

Keywords: diagnostic hysteroscopy; operative hysteroscopy; uterine sampling; uterine polyp; submucosal fibroid; hysteroscopic dilatation and curettage; hysteroscopic niche repair

(This special issue belongs to the Section Obstetrics & Gynecology)

High-Risk Pregnancy Management: From Prenatal Care to Postpartum Outcomes

edited by

Angela Vinturache

submission deadline 25 Jul 2026 | Viewed by 71 | Submission Open

Keywords: high-risk pregnancy; prenatal care; postpartum outcomes; postpartum mental health; birth trauma; AI in obstetrics; medico-legal liability; equity & culturally safe care; indigenous and rural/remote care; EMR-enabled decision support; quality trend monitoring; maternal morbidity and mortality; perinatal morbidity; standardized care bundles & pathways

(This special issue belongs to the Section Obstetrics & Gynecology)

Sleep Disorders: Current Research and Future Directions—Second Edition

edited by Martina Vendrame

submission deadline 25 Jul 2026 | Viewed by 69 | Submission Open

Keywords: obstructive sleep apnea; parasomnia; idiopathic hypersomnia; periodic limb movement disorder; periodic limb move-ment of sleep

(This special issue belongs to the Section Clinical Neurology)

Clinical Updates on Transcatheter Structural Heart Disease Interventions

edited by Nazan Puluca and Hendrik Ruge

submission deadline 25 Jul 2026 | Viewed by 69 | Submission Open

Keywords: interventional valve therapy; TAVR; TEER; TMVR; mitral valve; tricuspid valve; coronary access

(This special issue belongs to the Section Cardiology)

Recent Advance in Bariatric Surgery

edited by

Lidia Castagneto Gissey

submission deadline 25 Jul 2026 | Viewed by 63 | Submission Open

Keywords: bariatric surgery; metabolic surgery; minimally invasive surgery; robotic surgery; endoscopic bariatric procedures; obesity management; type 2 diabetes remission; perioperative care; long-term outcomes; enhanced recovery

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Management Strategies for Coronary Artery Disease and Revascularization

edited by

Marco Spagnolo

submission deadline 25 Jul 2026 | Viewed by 60 | Submission Open

Keywords: coronary artery disease; coronary revascularization; coronary physiology; coronary imaging; antithrombotic therapy

(This special issue belongs to the Section Cardiovascular Medicine)

Complications Related to Coronary Artery Disease and Secondary Prevention Strategies

edited by Nazanin Rajai

submission deadline 25 Jul 2026 | Viewed by 58 | Submission Open

Keywords: coronary artery disease; complications; secondary prevention; myocardial infarction; cardiovascular risk; heart failure; arrhythmias; imaging; biomarkers; cardiovascular pharmacotherapy

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Application of Endoscopic Submucosal Dissection in Malignant Gastrointestinal Tumors and Precursors—2nd Edition

edited by

Rainer Schöfl

and

Reinhold Függer

submission deadline 25 Jul 2026 | Viewed by 57 | Submission Open

Keywords: endoscopy; endoscopic submucosal dissection; endoscopic surgery; laparoscopic surgery; minimally invasive surgery

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Diagnosis and Treatment of Pleura and Lung: Clinical Advances in Intensive Care

edited by Alen Protić and

Vlatka Sotosek

submission deadline 25 Jul 2026 | Viewed by 54 | Submission Open

Keywords: thoracic drainage; lung recruitment; lung ultrasound; pleural effusion; pneumothrax; B-line; lung atelectasis

(This special issue belongs to the Section Intensive Care)

Hearing Loss Management in Children: Guidelines and Interventions

edited by Lone Percy-Smith

submission deadline 25 Jul 2026 | Viewed by 53 | Submission Open

Keywords: early intervention for populations with HL; emerging new generations of persons with HL; quality assurance of interventions for populations with HL; self-assessments of quality of life

(This special issue belongs to the Section Clinical Pediatrics)

Obstructive Sleep Apnea: Advances in Clinical Diagnosis and Management

edited by

Gonzalo Labarca

submission deadline 25 Jul 2026 | Viewed by 46 | Submission Open

Keywords: obstructive sleep apnea; sleep disorder breathing; central apnea; apnea– hypopnea index; precision medicine

(This special issue belongs to the Section Respiratory Medicine)

Current Advances and Future Perspectives in Cardiac Arrest and Cardiogenic Shock

edited by Giulia Maj

submission deadline 25 Jul 2026 | Viewed by 44 | Submission Open

Keywords: cardiogenic shock; left ventricular unloading; biomarkers; recovery; cardiac arrest

(This special issue belongs to the Section Emergency Medicine)

Interaction Between Systemic Diseases and Oral Diseases: 2nd Edition

edited by

Henk S. Brand

submission deadline 25 Jul 2026 | Viewed by 38 | Submission Open

Keywords: medical dental interaction; saliva; xerostomia; diagnostics; inflammatory bowel disease; cancer survivors; dental erosion; Sjö gren’ s disease; liver transplantation

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Cardiac Electrophysiology: New Insights and Future Directions: 2nd Edition

edited by

Michael Spartalis

submission deadline 25 Jul 2026 | Viewed by 31 | Submission Open

Keywords: catheter ablation; pulsed-field ablation; conduction-system pacing; arrhythmias; implantable cardiac devices; leadless pacing; mapping technologies; digital health; artificial intelligence; sudden cardiac death

(This special issue belongs to the Section Cardiology)

Updates in the Diagnosis, Imaging, and Treatment of Retinal and Macular Diseases

edited by

Makoto Inoue

submission deadline 26 Jul 2026 | Viewed by 70 | Submission Open

Keywords: retinal diseases; macular degeneration; diagnostic imaging; OCT/OCTA; artificial intelligence; deep learning; clinical ophthalmology; gene therapy; treatment innovations

(This special issue belongs to the Section Ophthalmology)

Clinical Diagnosis and Treatment Strategies in Sjogren's Disease (SjD)

edited by

Nancy L. Carteron

Ava Wu

and Nancy McNamara

submission deadline 29 Jul 2026 | Viewed by 58 | Submission Open

Keywords: Sjogren; Sjogren’ s disease; lymphocytic tissue infiltration; interdisciplinary care; pathogenesis; caries; corneal erosions; autoimmunity; lymphoproliferative (or lymphoma)

(This special issue belongs to the Section Immunology & Rheumatology)

Improving Outcomes in Systemic Lupus Erythematosus: Latest Advances and Prospects in Relation to Comorbidity, Damage, and Quality of Life

edited by

Oshrat E. Tayer-Shifman

and Shaye Kivity

submission deadline 30 Jul 2026 | Viewed by 89 | Submission Open

Keywords: systemic lupus erythematosus; comorbidities; outcome measures; damage accrual; quality of life; cognitive im-pairment; infections and vaccination; treat-to-target; digital biomarkers

(This special issue belongs to the Section Immunology & Rheumatology)

Clinical Insights and Applications in Cardiac Electrophysiology

edited by

Alberto Preda

and Fabrizio Guarracini

submission deadline 30 Jul 2026 | Viewed by 68 | Submission Open

Keywords: atrial fibrillation; catheter ablation; transvenous lead extraction; left atrial appendage occlusion; heart failure; subcutaneous ICD; extravascular ICD; conduction system pacing; cardiac electrophysiology; cardiac rhythm disorders; arrhythmia mapping; supraventricular arrhythmias; ventricular arrhythmias; cardiomyopathies; implantable cardiac devices; minimally invasive devices; left atrial appendage closure; personalized arrhythmia care; clinical management; innovative electrophysiological techniques

(This special issue belongs to the Section Cardiology)

Clinical and Laboratory Applications of Artificial Intelligence in Haematology

edited by

Emmanuel Favaloro

and Bingwen Eugene Fan

submission deadline 30 Jul 2026 | Viewed by 63 | Submission Open

Keywords: hematology; artificial intelligence/AI; machine learning/ML; innovation; hemostasis; thrombosis; diagnostics; prog-nosis; laboratory automation; clinical decision support; precision medicine; big data; digital pathology

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Clinical Medicine)

Endoscopic Management of Pancreaticobiliary Diseases

edited by

Kamran Ayub

submission deadline 30 Jul 2026 | Viewed by 56 | Submission Open

Keywords: pancreaticobiliary endoscopy; endoscopic ultrasound (EUS); endoscopic retrograde cholangiopancreatography (ERCP); biliary drainage; gallbladder drainage; lumen-opposing metal stents; cholangioscopy; pancreatoscopy; confocal laser endomicroscopy; pancreatic cysts; molecular diagnostics; lithotripsy (electrohydraulic and laser); radiofrequency ablation (RFA); photodynamic therapy (PDT); pancreatic and biliary tumors; interventional endoscopy; altered anatomy access; diagnostic and therapeutic endoscopy

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Integrated Assessment and Management of Heart Failure Syndromes

edited by Damiano Magrì and Emiliano Fiori

submission deadline 30 Jul 2026 | Viewed by 53 | Submission Open

Keywords: heart failure; functional capacity; multimodality assessment; advanced imaging; coronary and structural interventions; device therapies

(This special issue belongs to the Section Cardiology)

Innovations in Elbow and Shoulder Surgery: Techniques, Outcomes, and Rehabilitation

edited by Andrea Celli

submission deadline 30 Jul 2026 | Viewed by 42 | Submission Open

Keywords: orthopedic; elbow surgery; shoulder surgery; infection; nonunion; malunion; ligaments injuries; tendon injuries; el-bow and shoulder replacement; arthroscopy

(This special issue belongs to the Section Orthopedics)

Effects of Exercise Training on Physiological and Functional Outcomes in Age and Frailty

edited by

Dihogo Gama de Matos

and

Rodrigo Villar

submission deadline 30 Jul 2026 | Viewed by 35 | Submission Open

Keywords: exercise training ; older adults ; frailty ; cardiovascular system ; autonomic system ; quality of life ; healthy aging ; functional capacity

(This special issue belongs to the Section Geriatric Medicine)

Clinical Application of Physical Therapy in Neurorehabilitation: 3rd Edition

edited by

Sofia Straudi

and

Roberto Cano de la Cuerda

submission deadline 31 Jul 2026 | 2 articles | Viewed by 628 | Submission Open

Keywords: physical therapy; technology-aided rehabilitation; exercise; neurorehabilitation; neuroplasticity; engagement; self-management

(This special issue belongs to the Section Clinical Rehabilitation)

Psychogerontology: Psychological Insights into Aging

edited by Sónia Martins and

Sara Lima

submission deadline 31 Jul 2026 | Viewed by 486 | Submission Open

Keywords: psychogerontology; aging process; adjustment; mental health; psychopatology; personality; emotions; well-being; spir-ituality; quality of life; caregiving; psychogerontology assessment and interventions

(This special issue belongs to the Section Mental Health)

Neuro-Psychiatric Disorders: Updates on Diagnosis and Treatment—2nd Edition

edited by

Georgios Floros

submission deadline 31 Jul 2026 | Viewed by 46 | Submission Open

Keywords: neuropsychiatric disorder; diagnosis; treatment; neurobiology; organic psychiatry

(This special issue belongs to the Section Mental Health)

Breakthroughs in the Treatment of Colorectal Cancer

edited by Laura Fortuna and

Andrea Bottari

submission deadline 31 Jul 2026 | Viewed by 45 | Submission Open

Keywords: colorectal cancer; targeted therapy; minimally invasive surgery; immune– oncology integration; enhanced recovery protocols; multidisciplinary care

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

The Future Direction of Medical Imaging in Hepato-Bilio-Pancreatic Oncology: Challenges and Opportunities

edited by

Nicolò Brandi

submission deadline 31 Jul 2026 | Viewed by 43 | Submission Open

Keywords: MRI; CT; molecular imaging; radiomics; imaging; radiogenomics; precision medicine; outcome prediction; cholangiocarcinoma; pancreatic cancer; imaging biomarkers; treatment response

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Pulmonary Hypertension: From Pathophysiology to Clinical Management

edited by

Dirk Bandorski

and

Lukas Ley

submission deadline 31 Jul 2026 | Viewed by 40 | Submission Open

Keywords: pulmonary hypertension; pulmonary arterial hypertension; chronic thromboembolic pulmonary hypertension; pulmonary endarterectomy; balloon pulmonary angioplasty; pharmacological treatment; pathophysiology

(This special issue belongs to the Section Respiratory Medicine)

Interventional Cardiology: Evolving Evidence and Emerging Horizons

edited by

Jacek Bil

submission deadline 31 Jul 2026 | Viewed by 39 | Submission Open

Keywords: coronary artery disease; percutaneous coronary intervention; drug-coated balloon; intravascular imaging; fractional flow reserve; transcatheter aortic valve implantation; transcatheter mitral valve repair; clinical outcomes

(This special issue belongs to the Section Cardiology)

Advances in Artificial Intelligence Applications for Invasive and Non-Invasive Cardiovascular Procedures

edited by

Oladipupo Olafiranye

and Rahul Chaudhary

submission deadline 31 Jul 2026 | Viewed by 37 | Submission Open

Keywords: artificial intelligence and machine learning; interventional cardiology; electrophysiology; cardiovascular imaging; remote patient monitoring; digital biomarkers; clinical decision support

(This special issue belongs to the Section Cardiovascular Medicine)

Blood Pressure Disorders: Risk Assessment, Surveillance and Clinical Interventions

edited by

Barbara Nikolaidou

submission deadline 7 Aug 2026 | Viewed by 24 | Submission Open

Keywords: hypertension; secondary hypertension; hypotension; target organ damage; hypertension phenotypes; hypertension emergency; hypertension urgency; microangiopathy; macroangiopathy; endothelial dysfunction; hypovolaemia; cardiogenic shock; dysautonomia

(This special issue belongs to the Section Cardiovascular Medicine)

Sports Cardiology: Current Clinical Status and Outlook into the Future

edited by Aakash Bavishi and Matthew W Martinez

submission deadline 10 Aug 2026 | Viewed by 83 | Submission Open

Keywords: sports cardiology; athletes; cardiac imaging; hypertrophic cardiomyopathy; screening; electrocardiogram; electrophysiology; echocardiography; sudden cardiac death

(This special issue belongs to the Section Cardiology)

New Insights into Glaucoma: 2nd Edition

edited by

Su-Ho Lim

and

Daniel Laroche

submission deadline 10 Aug 2026 | Viewed by 65 | Submission Open

Keywords: glaucoma; intraocular pressure (IOP); risk calculators; glaucoma screening glaucoma surgery; cataract surgery; trabeculectomy; glaucoma drainage devices; minimally invasive glaucoma surgery (MIGS); artificial intelligence (AI)

(This special issue belongs to the Section Ophthalmology)

Advances in Musculoskeletal Rehabilitation and Functional Movement

edited by Sanghee Park

submission deadline 13 Aug 2026 | Viewed by 35 | Submission Open

Keywords: corrective exercise; functional training; biomechanics; resistance training; movement impairment; electromyography; muscle activation; musculoskeletal rehabilitation

(This special issue belongs to the Section Clinical Rehabilitation)

Displaying special issue 1401-1450 on page 29 of 31.

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