Special Issue "Helicobacter pylori Infection and Gastritis"
Deadline for manuscript submissions: closed (15 May 2019).
Interests: gastric cancer; gastritis; Helicobacter pylori Infection; gastrointestinal endoscopy
Helicobacter pylori (H. pylori) leads to gastritis in the human stomach, with significant changes in terms of microbial composition. Nonetheless, most infected subjects are asymptomatic in an endemic area of H. pylori infection. Therefore, it is important to discriminate H. pylori-infected subjects using serology and endoscopy findings, regardless of symptoms. Nevertheless, there are few data on various stages of H. pylori-related gastritis. Furthermore, there is no comparison study on the different microbial environment between the “chronic gastritis with a risk of intestinal-type gastric cancer in hypochlorhydric environments” and the “active gastritis with a risk of diffuse-type gastric cancer in hyperacidic conditions”. The severity of gastritis, based on endoscopy and histopathological findings, should be discussed in the near future, with gastric secretory ability reflected using serum pepsinogen assay. This will help in understanding the differences between H. pylori-induced microbial dysbiosis in active gastritis and microbial diversity in chronic gastritis.
Prof. Dr. Sun-Young Lee
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- Helicobacter pylori
- Gastric cancer