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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Insights into Glaucoma: 2nd Edition

edited by

Su-Ho Lim

and

Daniel Laroche

submission deadline 10 Aug 2026 | Viewed by 62 | Submission Open

Keywords: glaucoma; intraocular pressure (IOP); risk calculators; glaucoma screening glaucoma surgery; cataract surgery; trabeculectomy; glaucoma drainage devices; minimally invasive glaucoma surgery (MIGS); artificial intelligence (AI)

(This special issue belongs to the Section Ophthalmology)

Advances in Musculoskeletal Rehabilitation and Functional Movement

edited by Sanghee Park

submission deadline 13 Aug 2026 | Viewed by 34 | Submission Open

Keywords: corrective exercise; functional training; biomechanics; resistance training; movement impairment; electromyography; muscle activation; musculoskeletal rehabilitation

(This special issue belongs to the Section Clinical Rehabilitation)

Spine Surgery: Novel Challenges and Opportunities

edited by

Tae-Hwan Kim

submission deadline 15 Aug 2026 | Viewed by 79 | Submission Open

Keywords: spine surgery; surgical outcomes; postoperative care; complications; epidemiology; diagnostic imaging; biomaterials; biomechanics; machine learning; artificial intelligence; predictive modeling; minimally invasive techniques; population-based studies; clinical decision-making

(This special issue belongs to the Section Orthopedics)

Neurovascular Canvas: From Basic Science to Clinical Breakthroughs

edited by

Ciro De Luca

, Nicola Giannini and

Alessandro Viganò

submission deadline 15 Aug 2026 | Viewed by 67 | Submission Open

Keywords: neurovascular unit (NVU); neurodegeneration; vascular biology; stroke; disease modeling

(This special issue belongs to the Section Clinical Neurology)

Clinical Neuroscience Insights: Exploring the Advances in Brain Health

edited by

Simona Massimino

and Francesco Tomaiuolo

submission deadline 15 Aug 2026 | Viewed by 38 | Submission Open

Keywords: neurodegenerative diseases; cognitive impairment; neuromodulation therapy; brain health; cognitive and affective processes; neurorehabilitation

(This special issue belongs to the Section Clinical Neurology)

From Gastritis to Gastric Cancer: Challenges in Diagnosis and Long-term Management

edited by

Zuzanna Pelc

and

Karol Rawicz-Pruszyński

submission deadline 15 Aug 2026 | Viewed by 31 | Submission Open

Keywords: gastric cancer; gastritis and H. pylori; early detection and endoscopy; multimodal treatment; molecular profiling (MSI/MMR; PD-L1; CLDN18.2; HER2)

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Gene Correction and Regenerative Therapies for Inherited Retinal Diseases: Clinical Perspectives

edited by Sushma Kalmodia

submission deadline 15 Aug 2026 | Viewed by 30 | Submission Open

Keywords: gene therapy; AAV; IRD; retinal organoids; RPE

(This special issue belongs to the Section Ophthalmology)

Redefining Hemodialysis: Beyond Diffusion to Precision Therapy

edited by

Stefano Stuard

and Sagar Nigwekar

submission deadline 15 Aug 2026 | Viewed by 27 | Submission Open

Keywords: digitalized medical governance; precision dialysis; convective clearance; advanced membranes; hemodynamic stability; artificial intelligence; digital biomarkers; personalized prescription; cardiovascular protection; patient-reported outcome measures; clinical trial emulation

(This special issue belongs to the Section Nephrology & Urology)

Advances in the Diagnosis, Treatment and Prognosis of Aortic Stenosis: 2nd Edition

edited by Rita Milewski

submission deadline 15 Aug 2026 | Viewed by 27 | Submission Open

Keywords: aortic valve stenosis; aortic valve replacement; surgical aortic valve replacement; transfemoral aortic valve replacement; risk stratification for aortic stenosis

(This special issue belongs to the Section Cardiology)

From Imaging to Intervention: Modern Approaches in Spine Disorders Management

edited by

Maria Chiara Maccarone

submission deadline 15 Aug 2026 | Viewed by 27 | Submission Open

Keywords: adolescent idiopathic scoliosis (AIS); spinal fusion; Cobb angle; bracing; skeletal maturity; radiographic imaging; multidisciplinary management

(This special issue belongs to the Section Orthopedics)

Hypertension and Cardiovascular Disease: Clinical Updates and Perspectives: 2nd Edition

edited by

Valeria Visco

submission deadline 15 Aug 2026 | Viewed by 26 | Submission Open

Keywords: hypertension management; cardiovascular risk assessment; novel antihypertensive therapies; hypertension in pregnancy; hypertensive emergencies; cardiovascular disease prevention; pharmacological interventions for cardiovascular disease

(This special issue belongs to the Section Cardiovascular Medicine)

Patient Safety and Clinical Outcomes in Robotic-Assisted Microsurgery and Endoscopic Surgery

edited by Tetsuji Uemura

submission deadline 15 Aug 2026 | Viewed by 13 | Submission Open

Keywords: endoscopic surgery; reconstructive surgery; robotic-assisted microsurgery; advanced surgical technologies; patient safety

(This special issue belongs to the Section General Surgery)

Advances in the Diagnosis and Management of Age-Related Macular Degeneration: 3rd Edition

edited by Tsutomu Yasukawa

submission deadline 20 Aug 2026 | Viewed by 228 | Submission Open

Keywords: age-related macular degeneration; angiography; anti-vascular endothelial growth factor therapy; geographic atrophy; macular neovascularization; multimodal imaging; ophthalmology; optical coherence tomography; photodynamic therapy; retinal pigment epithelium

(This special issue belongs to the Section Ophthalmology)

New Insights into Gastrointestinal Surgery: Advances in Techniques and Treatment Approaches

edited by Gabriella Teresa Capolupo

submission deadline 20 Aug 2026 | Viewed by 118 | Submission Open

Keywords: gastroenterology; gastrointestinal surgery; colorectal surgery; robotic surgery; technologies; minimally invasive surgery

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

From Clinical Diagnosis to Effective Treatment of Cardiomyopathy

edited by

Sanjay Sivalokanathan

and

Łukasz A. Małek

submission deadline 20 Aug 2026 | Viewed by 93 | Submission Open

Keywords: hypertrophic cardiomyopathy; dilated cardiomyopathy; non-ischemic cardiomyopathy; cardiac MRI; PET/CT; PET/MRI; cardiac imaging; sudden cardiac death

(This special issue belongs to the Section Cardiology)

Current Trends and Innovations in Coronary Artery Disease and Myocardial Ischemia: Second Edition

edited by

Edoardo Conte

submission deadline 20 Aug 2026 | Viewed by 74 | Submission Open

Keywords: coronary artery disease; fractional flow reserve; invasive coronary angiography; cardiac CT; cardiac MRI

(This special issue belongs to the Section Cardiovascular Medicine)

Sepsis and Septic Shock: Diagnosis, Treatment, and Prognosis

edited by Luigi Carbone and Daniela Pugliese

submission deadline 20 Aug 2026 | Viewed by 71 | Submission Open

Keywords: sepsis; septic shock; diagnosis and screening tools; risk stratification; machine learning; advanced therapies

(This special issue belongs to the Section Intensive Care)

Physical Therapy in Musculoskeletal Disorders: Prevention, Diagnosis, Clinical Management and Treatment—2nd Edition

edited by

Rubén Cuesta-Barriuso

submission deadline 20 Aug 2026 | Viewed by 66 | Submission Open

Keywords: physical therapy; musculoskeletal disorders; prevention; diagnosis; clinical management; treatment

(This special issue belongs to the Section Clinical Rehabilitation)

Advances in the Management of Cervical Spine Trauma

edited by

Jong-Beom Park

and

Sung-kyu Kim

submission deadline 20 Aug 2026 | Viewed by 58 | Submission Open

Keywords: cervical spine trauma; cervical fracture; high cervical injury; subaxial injury; surgical management; occipitocervical fusion; C1 fracture; C2 fracture; spinal stability; trauma imaging; spinal cord injury; neurological outcome

(This special issue belongs to the Section Orthopedics)

Retinal Diseases: Recent Advances in Diagnosis and Treatment—2nd Edition

edited by Dario Giorgio and Dario Pasquale Mucciolo

submission deadline 20 Aug 2026 | Viewed by 56 | Submission Open

Keywords: retinal diseases; retinal degeneration; macular degeneration; OCT; retinal imaging

(This special issue belongs to the Section Ophthalmology)

Anterior Segment Disorders

edited by Itay Lavy and

Nir Erdinest

submission deadline 20 Aug 2026 | Viewed by 52 | Submission Open

Keywords: anterior segment disorders; corneal disease; cataract surgery; ocular surface disease; surgical outcomes; surgical techniques; artificial intelligence in diagnosis; diagnostic imaging; pharmacological and surgical interventions; refractive errors; anterior uveitis; keratitis; corneal ectasia; quality of life

(This special issue belongs to the Section Ophthalmology)

Clinical Updates on Reproductive Endocrinology in Children and Adolescents

edited by

Charikleia Stefanaki

submission deadline 20 Aug 2026 | Viewed by 49 | Submission Open

Keywords: reproductive endocrinology; adolescents; male hypogonadism; female hypogonadism; reproductive metabolism; PCOS; POF; receptor abnormalities; menstrual cycle; transgender health; CAH; ovaries; gonads; hormones; sex development; amenorrhea; estrogen resistance; androgen resistance; teen pregnancy; oncology; preservation of fertility

(This special issue belongs to the Section Clinical Pediatrics)

Precision Neuroimaging in Mental and Behavioral Health Research

edited by Thomas Vanicek and Arkadiusz Komorowski

submission deadline 20 Aug 2026 | Viewed by 49 | Submission Open

Keywords: psychiatry; neuroimaging; addiction; substance use disorders (SUD); attention deficit hyperactivity disorder (ADHD); imaging genomics; imaging transcriptomics

(This special issue belongs to the Section Mental Health)

Non-Pharmacological Therapies and Exercise Interventions in Clinical Populations

edited by

Jorge Sánchez-Infante

submission deadline 20 Aug 2026 | Viewed by 49 | Submission Open

Keywords: non-pharmacological interventions; physiotherapy approaches; physical activity; acute and chronic diseases; acute and chronic pain

(This special issue belongs to the Section Clinical Rehabilitation)

Enhancing and Rehabilitation of Gait and Mobility in Chronic Stroke

edited by

Maria-Arantzazu Ruescas-Nicolau

Marco Iosa

and

María Luz Sánchez-Sánchez

submission deadline 20 Aug 2026 | Viewed by 47 | Submission Open

Keywords: chronic stroke; gait rehabilitation; mobility; physical therapy; technology-assisted interventions; assessment

(This special issue belongs to the Section Clinical Neurology)

Clinical Advances in Orthopedic Infections: 2nd Edition

edited by

Hyonmin Choe

submission deadline 20 Aug 2026 | Viewed by 44 | Submission Open

Keywords: orthopedic surgery; orthopedic infections; periprosthetic joint infection; surgical site infection; infection management

(This special issue belongs to the Section Orthopedics)

Spine Neurosurgery: Latest Advances and Prospects

edited by Jun Jae Shin, Bong Ju Moon and Chang Kyu Lee

submission deadline 20 Aug 2026 | Viewed by 44 | Submission Open

Keywords: cervical spine; cervical myelopathy; ossification of the posterior longitudinal ligament (OPLL); endoscopic spine surgery; minimally invasive spine surgery; spinal deformity

(This special issue belongs to the Section Clinical Neurology)

Diagnosis and Clinical Management in Hematologic Oncology

edited by Sunil Lakhwani and José María Raya-Sánchez

submission deadline 20 Aug 2026 | Viewed by 43 | Submission Open

Keywords: hematologic malignancies; lymphoma; multiple myeloma; acute leukemia; myeloproliferative neoplasms; molecular diagnostics; targeted therapy; immunotherapy; prognostic biomarkers; clinical management

(This special issue belongs to the Section Hematology)

Clinical Approaches of Intracranial Aneurysm and Subarachnoid Hemorrhage

edited by Sylvia Bele

submission deadline 20 Aug 2026 | Viewed by 42 | Submission Open

Keywords: aSAH; clipping or coiling; extracranial complications; cerebral vasospasm; ICU treatment

(This special issue belongs to the Section Clinical Neurology)

Orthopaedic Trauma and Bone Healing: Recent Advances and Future Perspectives

edited by Gheorghe Tomoaia and Daniel Oltean-Dan

submission deadline 20 Aug 2026 | Viewed by 42 | Submission Open

Keywords: orthopaedic trauma; fractures; minimally invasive fixation; bone healing; biomaterials; periprosthetic fractures; artificial intelligence; rehabilitation; complications; orthopaedic surgery

(This special issue belongs to the Section Orthopedics)

Clinical Advances in Hearing Loss: Diagnosis, Treatment, and Management

edited by

Wojciech Gawȩcki

submission deadline 20 Aug 2026 | Viewed by 40 | Submission Open

Keywords: hearing loss; deafness; bone conduction implants; middle ear implants; cochlear implants; myringoplasty; tympanoplasty; stapedotomy; ossicular chain reconstruction; imaging; audiological diagnostic

(This special issue belongs to the Section Otolaryngology)

Recent Clinical Perspectives on Chronic Kidney Disease

edited by Luca Visconti

submission deadline 20 Aug 2026 | Viewed by 39 | Submission Open

Keywords: chronic kidney disease; nephrology; hemodialysis; renal impairment; renal replacement therapy; new therapeutic approaches in CKD; clinical trials; renal complications

(This special issue belongs to the Section Nephrology & Urology)

Physiotherapy: Multidisciplinary Interventions and Digital Health

edited by

Esteban Obrero-Gaitán

and

Irene Cortés Pérez

submission deadline 20 Aug 2026 | Viewed by 39 | Submission Open

Keywords: physiotherapy; rehabilitation; physical medicine; digital health; telemedicine; virtual reality; augmented reality; artifi-cial intelligence; robotic rehabilitation; wearable sensors; VR for educative goals; musculoskeletal; neurological; cognitive; pediatric; pulmonary; cardiac and gyneco-obstetric disorders; fibromyalgia syndrome; chronic pain; older adults

(This special issue belongs to the Section Clinical Rehabilitation)

The Liver–Kidney Axis in Metabolic Diseases: Biomarkers and Clinical Implications

edited by

Anna Di Sessa

submission deadline 20 Aug 2026 | Viewed by 38 | Submission Open

Keywords: liver; kidney; cross-organ crosstalk; mechanisms; biomarkers; metabolic diseases; clinical implications

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Heart Failure and Transplant Cardiology: Latest Advances and Prospects

edited by Monika Budnik

submission deadline 20 Aug 2026 | Viewed by 38 | Submission Open

Keywords: heart failure; heart transplantation; bridge to transplant; mechanical circulatory support; cardiomyopathies

(This special issue belongs to the Section Cardiology)

Breaking the Barrier: Early Detection of Pancreatic Ductal Adenocarcinoma (PDAC)

edited by

Ewa Małecka-Wojciesko

submission deadline 20 Aug 2026 | Viewed by 37 | Submission Open

Keywords: pancreatic ductal adenocarcinoma (PDAC); pancreatic cancer; IPMN; PDAC screening; early PDAC detection; PDAC biomarkers; CT; NMR

(This special issue belongs to the Section Oncology)

Therapeutic Advances and Emerging Treatments in Inflammatory Bowel Disease

edited by

Laura Ramos

submission deadline 20 Aug 2026 | Viewed by 37 | Submission Open

Keywords: inflammatory bowel disease; therapeutic advances emerging treatments; biologics and small molecules; precision medicine in IBD; pharmacokinetic model

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Recent Advances in Hypercholesterolemia

edited by Ana Catarina Alves

submission deadline 20 Aug 2026 | Viewed by 36 | Submission Open

Keywords: hypercholesterolemia; cardiovascular risk; molecular diagnostics; variants of uncertain significance (VUS); functional characterisation; precision medicine; lipid-lowering therapy

(This special issue belongs to the Section Endocrinology & Metabolism)

Updates on Embolization and Embolotherapy for Benign Prostatic Hyperplasia and Men’s Health

edited by Sandeep L. Bagla, Ari J. Isaacson and Abin Sajan

submission deadline 20 Aug 2026 | Viewed by 36 | Submission Open

Keywords: benign prostatic hyperplasia; prostatic artery embolization; men’ s health; lower urinary tract symptoms; embolization therapy; radiation safety; prostate cancer and radiotherapy

(This special issue belongs to the Section Nephrology & Urology)

Advances in Diagnosis, Monitoring, and Treatment of Myocardial Infarction

edited by

Rita Pavasini

submission deadline 20 Aug 2026 | Viewed by 35 | Submission Open

Keywords: myocardial infarction (MI); occlusion myocardial infarction (OMI); myocardial infarction with non-obstructive coronary arteries (MINOCA); diagnosis; monitoring; treatment

(This special issue belongs to the Section Cardiovascular Medicine)

Clinics and Management of Allergic and Inflammatory Skin Disorders

edited by

Andrzej Jaworek

and

Marta Szepietowska

submission deadline 20 Aug 2026 | Viewed by 33 | Submission Open

Keywords: allergic dermatoses; chronic inflammatory dermatoses; atopic dermatosis; contact dermatitis; chronic urticria; rosacea; psoriasis; hidradenitis suppurativa; diagnosis; comorbidities; management

(This special issue belongs to the Section Dermatology)

Pharmacological Pain Management Advances

edited by Michael A. Ueberall

submission deadline 20 Aug 2026 | Viewed by 33 | Submission Open

Keywords: pain management; drug therapy; analgesics; co-analgesics; drug safety and drug interactions; real-world evidence

(This special issue belongs to the Section Anesthesiology)

Current Concepts and Technological Innovations in Hepato-Pancreato-Biliary Surgery and Transplantation

edited by Michele Finotti and Francesco D’Amico

submission deadline 20 Aug 2026 | Viewed by 33 | Submission Open

Keywords: hepato-pancreato-biliary surgery; hepato-pancreato-biliary transplantation; pancreatic cancer; hepatobiliary cancer; vascular reconstruction; minimally invasive in hepato-pancreato-biliary surgery; robotic techniques; organ-preservation strategies

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Contemporary Coronary Intervention: Innovation, Evidence, and Patient-Centred Outcomes

edited by Kevin Liou

submission deadline 20 Aug 2026 | Viewed by 32 | Submission Open

Keywords: percutaneous coronary interventions; coronary imaging; coronary physiology; precision medicine; CHIP PCI; stent-less technologies; clinical outcomes; pharmacotherapy in PCI; biomarkers; artificial intelligence in PCI; sustainability in PCI

(This special issue belongs to the Section Cardiology)

Anesthesia and Intensive Care: Clinical Practices and Prospects

edited by

Jungchan Park

submission deadline 20 Aug 2026 | Viewed by 32 | Submission Open

Keywords: artificial intelligence; clinical decision support; perioperative risk stratification; perioperative patient safety; hemodynamic optimization

(This special issue belongs to the Section Intensive Care)

Clinical Perspectives on Extracorporeal Membrane Oxygenation (ECMO)

edited by

Alexander Hermann

submission deadline 20 Aug 2026 | Viewed by 31 | Submission Open

Keywords: extracorporeal membrane oxygenation (ECMO); extracorporeal life support (ECLS); extracorporeal cardiopulmonary resuscitation (eCPR); extracorporeal gas exchange; extracorporeal circulation; acute respiratory distress syndrome (ARDS); cardiogenic shock (CS)

(This special issue belongs to the Section Intensive Care)

Advances in Trauma and Orthopedic Surgery: 3rd Edition

edited by

Christian von Rüden

submission deadline 20 Aug 2026 | Viewed by 31 | Submission Open

Keywords: trauma; fracture; fracture fixation; osteosynthesis; biomechanics; bone; approach; nonunion; joint replacement; outcome

(This special issue belongs to the Section Orthopedics)

Endometriosis: Advances in Diagnosis, Treatment, and Long-Term Outcomes

edited by

Francesco Martire

submission deadline 20 Aug 2026 | Viewed by 30 | Submission Open

Keywords: endometriosis; diagnosis and biomarkers; medical and surgical treatment; fertility and reproductive outcomes; pain management; quality of life; long-term follow-up

(This special issue belongs to the Section Obstetrics & Gynecology)

Endocrine Surgery: Current Treatment and Future Options

edited by Pietro Princi and

Julia Staubitz-Vernazza

submission deadline 20 Aug 2026 | Viewed by 30 | Submission Open

Keywords: endocrine surgery; thyroid surgery; parathyroid surgery; adrenal gland surgery; neuroendocrine neoplasms; thyroid cancer; thyroid cancer treatment; surgical endocrinology; robotic endocrine surgery; laparoscopic adrenalectomy; ret-roperitoneoscopic adrenalectomy; parathyroidectomy; benign thyroid disease; thyroid ablation

(This special issue belongs to the Section General Surgery)

Optimizing Blood Management in Perioperative Cardiac Care: A Multidisciplinary Approach

edited by

Paul Abraham

submission deadline 20 Aug 2026 | Viewed by 29 | Submission Open

Keywords: perioperative cardiac care; patient blood management; cardiac surgery; blood transfusion; transfusion thresholds; bleeding management; hemostatic therapy; anticoagulation management; point‑of‑care coagulation testing

(This special issue belongs to the Section Cardiology)

Displaying special issue 1451-1500 on page 30 of 31.

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