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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Aspects of Return to Sport After Injuries: 2nd Edition

edited by

Anna Mika

and

Łukasz Oleksy

submission deadline 20 May 2026 | Viewed by 89 | Submission Open

Keywords: musculoskeletal system; tissue overload; diagnostic methods; rehabilitation; treatment; injury prevention; return to sport; rehabilitation medicine; sports medicine

(This special issue belongs to the Section Sports Medicine)

Clinical Advances in Hemodialysis: 2nd Edition

edited by Maurizio Bossola

submission deadline 20 May 2026 | Viewed by 85 | Submission Open

Keywords: hemodialysis; interdialytic weight gain; symptom burden and quality of life; impaired cognitive function; fatigue; dietary restrictions; depression; anxiety; frailty; polypharmacy

(This special issue belongs to the Section Nephrology & Urology)

Clinical Advances in Ocular Surgeries: Innovations in Cataract, Retinal, and Beyond

edited by

Seung Pil Bang

and Yu Cheol Kim

submission deadline 20 May 2026 | Viewed by 84 | Submission Open

Keywords: cataract surgery; retinal surgery; intraocular lenses; femtosecond laser; minimally invasive vitrectomy; ocular imaging; surgical innovation; ocular trauma; corneal transplantation; glaucoma surgery

(This special issue belongs to the Section Ophthalmology)

Contemporary Advances in Joint Arthroplasty: Optimizing Outcomes and Expanding Indications

edited by

Ashim Gupta

and

Hugo C. Rodriguez

submission deadline 20 May 2026 | Viewed by 81 | Submission Open

Keywords: joint arthroplasty; total joint replacement; revision arthroplasty; robotic-assisted surgery; periprosthetic joint infection (PJI); enhanced recovery after surgery (ERAS); machine learning; artifical intelligence

(This special issue belongs to the Section Orthopedics)

Neurological Surgery: Clinical Advances and AI-Driven Innovations

edited by Ali A. Alattar

submission deadline 20 May 2026 | Viewed by 75 | Submission Open

Keywords: neurosurgery; artificial intelligence; machine learning; deep learning; radiomics; image segmentation; surgical video analytics; navigation and robotics; predictive modeling; clinical decision support

(This special issue belongs to the Section Clinical Neurology)

Acute Medical Threats: Evidence-Driven Strategies in Emergency Medicine

edited by

Alexandra Arvanitaki

submission deadline 20 May 2026 | Viewed by 74 | Submission Open

Keywords: emergency medicine protocols; acute medical care; trauma management; resuscitation; critical care; infectious disease preparedness

(This special issue belongs to the Section Emergency Medicine)

Advances in Diagnosis and Management of Scoliosis

edited by

Peter G. Passias

submission deadline 20 May 2026 | Viewed by 74 | Submission Open

Keywords: scoliosis; spinal deformities; therapeutic strategies; personalized care; quality of life

(This special issue belongs to the Section Orthopedics)

Transcatheter Aortic Valve Implantation and Replacement: Prospects and Challenges—2nd Edition

edited by Konstantinos Toutouzas and

Panayotis Vlachakis

submission deadline 20 May 2026 | Viewed by 72 | Submission Open

Keywords: TAVI; aortic stenosis; valve-in-valve; structural heart disease; TAVI-in-TAVI

(This special issue belongs to the Section Cardiology)

Bladder Cancer: Diagnosis, Treatment and Future Opportunities

edited by

Jørgen Bjerggaard Jensen

submission deadline 20 May 2026 | Viewed by 72 | Submission Open

Keywords: urology; bladder cancer; urothelial cancer; non-muscle invasive bladder cancer; muscle invasive bladder cancer

(This special issue belongs to the Section Nephrology & Urology)

Myocardial Infarction: Current Status and Future Challenges—2nd Edition

edited by Isaac Pascual and

Rebeca Lorca

submission deadline 20 May 2026 | Viewed by 68 | Submission Open

Keywords: myocardial infarction; acute coronary syndrome (ACS); ischemic heart disease; coronary artery disease (CAD); percutaneous coronary intervention; pharmacological therapy; cardiovascular risk factors

(This special issue belongs to the Section Cardiology)

Spine Surgery and Rehabilitation: Technical Nuances and Outcomes

edited by Sehan Park and Dong-Ho Lee

submission deadline 20 May 2026 | Viewed by 68 | Submission Open

Keywords: spine surgery; rehabilitation; postoperative outcomes; surgical techniques; patient centered perspective

(This special issue belongs to the Section Orthopedics)

The Application of Mechanical Circulatory Support Within Cardiology Practice

edited by

Takami Yoshiyuki

submission deadline 20 May 2026 | Viewed by 66 | Submission Open

Keywords: mechanical circulatory support (MCS); cardiogenic shock; intra-aortic balloon pumping (IABP); extracorporeal membranous oxygenation (ECMO); Impella; ventricular assist device (VAD)

(This special issue belongs to the Section Cardiology)

Audiology and Phoniatrics in Head and Neck Surgery: Functional Assessment, Rehabilitation Strategies, and Quality of Life Outcomes

edited by

Claudia Cassandro

submission deadline 20 May 2026 | Viewed by 59 | Submission Open

Keywords: audiology; phoniatrics; voice disorders; hearing preservation; speech rehabilitation; head and neck surgery; functional outcomes; quality of life; voice analysis; audiometry; cochlear implants; dysphagia; laryngeal surgery

(This special issue belongs to the Section Otolaryngology)

Valvular Heart Disease: Current Knowledge and Therapeutic Prospects

edited by Simona Mega

submission deadline 20 May 2026 | Viewed by 58 | Submission Open

Keywords: valvular heart disease; echocardiographic assessment; cardiovascular imaging; valvular regurgitation; valvular stenosis; structural heart intervention; minimally invasive cardiac surgery; catheter-based interventions

(This special issue belongs to the Section Cardiology)

Clinical Advances in Venous Thrombosis

edited by Nicola Mumoli

submission deadline 20 May 2026 | Viewed by 57 | Submission Open

Keywords: direct oral anticoagulants (DOACs); cancer-associated thrombosis (CAT); venous thromboembolism (VTE); thrombolytic therapy; post-thrombotic syndrome (PTS); artificial intelligence in VTE prediction

(This special issue belongs to the Section Vascular Medicine)

Osteoporosis: A Renascent Impact of Vertebral Fractures in the Diagnosis and Management

edited by Csaba Horvath

submission deadline 20 May 2026 | Viewed by 53 | Submission Open

Keywords: osteoporosis; vertebral fractures; imminent fracture risk; FRAX; bone densitometry; vertebral fracture assessment

(This special issue belongs to the Section Orthopedics)

Clinical Challenges in Uterus Transplant Management

edited by Giuliano Testa

submission deadline 20 May 2026 | Viewed by 49 | Submission Open

Keywords: uterus transplant; absolute uterine infertility; fertility treatment; immunosuppression in uterus transplant; pregnancy complications; uterine donor evaluation

(This special issue belongs to the Section Obstetrics & Gynecology)

Current Understanding and Management of Asthma and Chronic Obstructive Pulmonary Disease

edited by Josuel Ora

submission deadline 20 May 2026 | Viewed by 44 | Submission Open

Keywords: asthma; chronic obstructive pulmonary disease (COPD); personalized medicine; exacerbations; biomarkers; inhalation therapy; digital health; artificial intelligence; pulmonary rehabilitation; comorbidities

(This special issue belongs to the Section Respiratory Medicine)

Clinical Features and Management of Psychosis

edited by

Maria Margariti

George Konstantakopoulos

and Michael Hadjulis

submission deadline 22 May 2026 | 4 articles | Viewed by 12240 | Submission Open

Keywords: psychosis; clinical features of psychosis; diagnosis of psychosis; schizophrenia; psychotic depression; affective disorder with psychotic features; psychosis in substance use disorders; psychosis in neurological disorders; psychosis in medical conditions; management of psychosis; treatment of psychosis

(This special issue belongs to the Section Mental Health)

Thoracic Surgery: Recent Developments and Future Challenges

edited by

Marco Andolfi

and Lucio Cagini

submission deadline 22 May 2026 | 1 articles | Viewed by 2831 | Submission Open

Keywords: VATS; RATS; ERAS; sublobar resection; minimally invasive thoracic surgery; target therapy; nodule localization

(This special issue belongs to the Section Respiratory Medicine)

Multiparametric Ultrasound Techniques for Liver Disease Assessments

edited by Francesco Giangregorio

submission deadline 22 May 2026 | 2 articles | Viewed by 2754 | Submission Open

Keywords: ultrasound; multiparametric ultrasound; hepatic ultrasound; contrast-enhanced ultrasound; contrast agents; diffuse hepatic diseases; focal liver lesions; hepatic elastography; liver stiffness; hepatic endosonography; hepatic EUS

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Clinical Updates on Rheumatoid Arthritis: 2nd Edition

edited by Francesca Bandinelli

submission deadline 22 May 2026 | 2 articles | Viewed by 1829 | Submission Open

Keywords: rheumatoid arthritis; rheumatology; treatment; diagnosis; biomarkers; rheumatic disease

(This special issue belongs to the Section Immunology & Rheumatology)

Thrombotic Risk and Its Management Across Diverse Clinical Settings

edited by Samuel Bogdan Todor and Ana Maria Vlǎdǎreanu

submission deadline 22 May 2026 | 1 articles | Viewed by 1809 | Submission Open

Keywords: thrombosis; thrombotic risk; hematologic disorders; thrombophilia; myeloproliferative neoplasms; antithrombotic therapy; cardiovascular diseases; biomarkers

(This special issue belongs to the Section Hematology)

Takotsubo Syndrome: Insights into Pathophysiology, Diagnosis, and Management

edited by

Andreas Mitsis

and

Nikolaos Kadoglou

submission deadline 22 May 2026 | 1 articles | Viewed by 837 | Submission Open

Keywords: takotsubo syndrome; stress cardiomyopathy; acute heart failure; cardiac imaging; catecholamine surge; myocardial dysfunction; echocardiography; biomarker discovery; cardiovascular risk; clinical management

(This special issue belongs to the Section Cardiology)

Role of Platelet in Inflammation, Infection, and Immune Response

edited by

Amir Houshang Shemirani

submission deadline 22 May 2026 | Viewed by 232 | Submission Open

Keywords: platelets; platelet count; dual antiplatelet therapy; inflammation; thrombosis; inflammation; hemostasis; immune response

(This special issue belongs to the Section Hematology)

Clinical Pharmacology: Adverse Drug Reactions

edited by

Andrej Belančić

and Ivana Mudnić

submission deadline 25 May 2026 | 7 articles | Viewed by 32153 | Submission Open

Keywords: pharmacology; adverse drug reactions; drug interactions; pharmacovigilance; drug safety

(This special issue belongs to the Section Pharmacology)

Neurovascular Diseases: Clinical Advances and Challenges

edited by

Roberto Colasanti

, Silky Chotai, Alessandro Di Rienzo and Joham Choque-Velasquez

submission deadline 25 May 2026 | 12 articles | Viewed by 27456 | Submission Open

Keywords: neurovascular diseases; ischemic stroke; hemorrhagic stroke; aneurysms; vascular malformations; diagnostic imaging; minimally invasive approaches; surgical techniques; endovascular interventions; treatment algorithms

(This special issue belongs to the Section Clinical Neurology)

Ventilation in Critical Care Medicine: 2nd Edition

edited by Gianluca Zani

submission deadline 25 May 2026 | 3 articles | Viewed by 17783 | Submission Open

Keywords: invasive ventilation; non-invasive ventilation; acute respiratory failure; best PEEP; respiratory weaning; respiratory mechanics; ventilation and perfusion; personalized ventilation

(This special issue belongs to the Section Intensive Care)

The Association Between Sleep Disorders and Metabolic and Mental Health

edited by

Filip Franciszek Karuga

Piotr Bialasiewicz

and

Marcin Sochal

submission deadline 25 May 2026 | 8 articles | Viewed by 15571 | Submission Open

Keywords: sleep medicine; sleep apnea; hypoxia; metabolism; mental health; women’ s health

(This special issue belongs to the Section Mental Health)

Maxillo-Facial Surgery: New Insights and Technologies in Head and Neck

edited by Federica Ruggiero

submission deadline 25 May 2026 | 6 articles | Viewed by 12728 | Submission Open

Keywords: oral and maxilla-facial surgery; orthognathic surgery; cranio-facial surgery; head and neck surgery; augmented reality; navigation; finite element modeling; virtual surgical planning; patient-specific implants

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Preventive, Diagnostic and Therapeutic Strategies for Abdominal Surgery Complications (Second Edition)

edited by

Orestis Ioannidis

submission deadline 25 May 2026 | 5 articles | Viewed by 10189 | Submission Open

Keywords: complications; diagnosis; treatment; management; morbidity; abdomen; abdominal surgery; outcome; postoperative

(This special issue belongs to the Section General Surgery)

Recent Progress in Rehabilitation Medicine—3rd Edition

edited by

Masahiro Kohzuki

submission deadline 25 May 2026 | 3 articles | Viewed by 9497 | Submission Open

Keywords: neuro-rehabilitation; cognitive rehabilitation; spinal rehabilitation; orthopedic rehabilitation; pediatric rehabilitation; cancer rehabilitation; visceral rehabilitation; cardiac rehabilitation; pulmonary rehabilitation; renal rehabilitation; hepatic rehabilitation; rehabilitation for transplantation; fitness; peak VO2; multimorbidity and multiple disabilities (MMD); adding life to years and years to life

(This special issue belongs to the Section Clinical Rehabilitation)

Oral and Maxillofacial Surgery: Diagnosis, Management and Future Opportunities

edited by

Federico Gelpi

submission deadline 25 May 2026 | 5 articles | Viewed by 9099 | Submission Open

Keywords: head and neck oncology; free flaps; oral surgery; malformative surgery; traumatology; endoscopy; preprosthetic surgery; reconstructive surgery; vascular malformations; osteonecrosis

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Diagnosis and Management of Vestibular Disorders

edited by

Sinisa Maslovara

, Mario Habek and

Andro Košec

submission deadline 25 May 2026 | 7 articles | Viewed by 8522 | Submission Open

Keywords: vertigo; dizziness; epidemiology; genetics; diagnostics; management

(This special issue belongs to the Section Otolaryngology)

Clinical Utility of Optical Coherence Tomography in Ophthalmology: 2nd Edition

edited by

Jose Ignacio Fernandez-Vigo

submission deadline 25 May 2026 | 5 articles | Viewed by 7958 | Submission Open

Keywords: optical coherence tomography; ophthalmology; intraoperative OCT; en face OCT; wide-field OCT; retinal diseases; glaucoma; cornea; strabismus; cataract

(This special issue belongs to the Section Ophthalmology)

Future Opportunities in Thoracic Surgery: The Cutting Edge: 2nd Edition

edited by

Giulio Maurizi

submission deadline 25 May 2026 | 2 articles | Viewed by 6291 | Submission Open

Keywords: surgical resection; immunotherapy; target therapy; thoracic surgery; thoracic oncology; lung cancer

(This special issue belongs to the Section Respiratory Medicine)

Assisted Reproductive Technology and Infertility Treatment: Current Updates and Perspectives—2nd Edition

edited by Nikos Nikolettos and

Angeliki Tiptiri-Kourpeti

submission deadline 25 May 2026 | 3 articles | Viewed by 4923 | Submission Open

Keywords: assisted reproduction technology (ART); infertility; treatment; reproduction; IVF

(This special issue belongs to the Section Reproductive Medicine & Andrology)

Novel Insights into the Diagnosis and Management of Inflammatory Bowel Disease (IBD)

edited by

Alina Ioana Tantau

submission deadline 25 May 2026 | 4 articles | Viewed by 4412 | Submission Open

Keywords: inflammatory bowel disease; non-invasive biomarkers; abdominal ultrasonography; colonoscopy; biologic therapy; small molecules; mucosal healing; brain-gut axis; dysbiosis; colorectal dysplasia

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

The Rebirth of Ventral Skull Base Surgery through Multiportal Approaches: Endonasal, Transorbital, Transmaxillary and Transoral Routes

edited by Matteo de Notaris and Francesco Corrivetti

submission deadline 25 May 2026 | 3 articles | Viewed by 3045 | Submission Open

Keywords: skull base surgery; neuroendoscopy; neuroanatomy; multiportal approaches; technical advancements

(This special issue belongs to the Section Clinical Neurology)

Clinical Highlights in Uveal Melanoma

edited by Tomasz Chorągiewicz and

Joanna Dolar-Szczasny

submission deadline 25 May 2026 | 1 articles | Viewed by 2612 | Submission Open

Keywords: choroidal melanoma; uveal melanoma; radiotherapy; enucleation; brachytherapy

(This special issue belongs to the Section Ophthalmology)

Autoimmune-Induced Alopecia and Emerging Therapies in Hair Loss—2nd Edition

edited by David Saceda-Corralo

submission deadline 25 May 2026 | 2 articles | Viewed by 2434 | Submission Open

Keywords: autoimmune-induced alopecia; alopecia areata; cicatricial alopecia; occurs; hair loss; frontal fibrosing alopecia

(This special issue belongs to the Section Dermatology)

Clinical Advances of Breast Surgery and Reconstruction

edited by

Glenda Giorgia Caputo

and

Emanuele Cigna

submission deadline 25 May 2026 | 1 articles | Viewed by 2275 | Submission Open

Keywords: breast reconstruction; autologous breast reconstruction; implant-based breast reconstruction; DIEP; LICAP; breast implant infection

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Modern Blood Banking and Transfusion in Clinical Practice: Second Edition

edited by

Pilar Solves

submission deadline 25 May 2026 | 2 articles | Viewed by 2256 | Submission Open

Keywords: blood transfusion therapy; patient blood management; restrictive transfusion; cell therapy; platelet transfusion

(This special issue belongs to the Section Hematology)

Clinical Advances in Gastrointestinal Endoscopy

edited by

Ivan Žaja

and Željko Puljiz

submission deadline 25 May 2026 | 3 articles | Viewed by 2236 | Submission Open

Keywords: endoscopy; polyps; EMR; ESD; POEM; balloon dilatation; coagulation; imaging; AI imaging

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Advanced Hepato-Pancreato-Biliary Surgery: Clinical Innovations and Improved Outcomes

edited by Ahmad Mahamid and Riad Haddad

submission deadline 25 May 2026 | 2 articles | Viewed by 2199 | Submission Open

Keywords: liver surgery; pancreas surgery; biliary surgery; robotic HPB surgery; single incision surgery; prognostic biomarkers; perioperative clinical care; postoperative complications

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Advances in the Clinical Management of Perioperative Anesthesia: 2nd Edition

edited by Alessia Mattei, Rita Cataldo and

Alessandro Strumia

submission deadline 25 May 2026 | 3 articles | Viewed by 2197 | Submission Open

Keywords: perioperative outcomes (surgical; anesthetic; medical); evidence-based care; perioperative guidelines and consensus statements; preoperative evaluation and risk scores; preoperative testing; surgical optimization and enhanced surgical recovery programs; intensive care unit

(This special issue belongs to the Section Anesthesiology)

Interstitial Lung Disease Secondary to Autoimmune Disorders: Recent Advances and Novel Perspectives

edited by

Gaetano La Rocca

Gianluca Sambataro

and Francesco Ferro

submission deadline 25 May 2026 | 1 articles | Viewed by 2178 | Submission Open

Keywords: interstitial lung disease; lung involvement; connective tissue diseases; rheumatoid arthritis; systemic vasculitis; radiomics; lung ultrasound; biomarkers; pathogenetic immunological pathways; therapeutic targets

(This special issue belongs to the Section Respiratory Medicine)

Current Clinical Advances in Urinary Incontinence

edited by Adolf Lukanovic, David Lukanović and Mija Blaganje

submission deadline 25 May 2026 | 3 articles | Viewed by 2082 | Submission Open

Keywords: female urinary incontinence; stress urinary incontinence; overactive bladder; diagnosis; prevention; conservative treatment; minimally invasive treatment; surgery; mid-urethral sling; new approach; energy-based devices

(This special issue belongs to the Section Nephrology & Urology)

Diabetic Foot: Emerging Prevention Strategies and Epidemiology

edited by

Vilma Urbančič-Rovan

submission deadline 25 May 2026 | 2 articles | Viewed by 1821 | Submission Open

Keywords: diabetic foot; foot clinics; epidemiology; prevention; screening; amputation; podiatry

(This special issue belongs to the Section Endocrinology & Metabolism)

Clinical Updates in Reproductive Endocrinology: 2nd Edition

edited by Iwona Bojar and

Dorota Raczkiewicz

submission deadline 25 May 2026 | 2 articles | Viewed by 1817 | Submission Open

Keywords: reproductive endocrinology; endocrine diseases in pregnancy; infertility; endocrine diagnostics in infertility; long-term consequences of endocrine disorders; therapy for endocrine disorders

(This special issue belongs to the Section Obstetrics & Gynecology)

Displaying special issue 1001-1050 on page 21 of 31.

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