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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Early Diagnosis and Treatment of Hepatitis B and C: Bridging Innovation and Implementation
edited by and
submission deadline 20 Jul 2026 | Submission Open
Keywords: hepatitis B virus (HBV); hepatitis C virus (HCV); hepatitis delta virus (HDV); early diagnosis; viral hepatitis elimination; functional cure; direct-acting antivirals (DAAs); antiviral therapy; treatment adherence; care cascade; screening programs; health policy
(This special issue belongs to the Section Infectious Diseases)
Sarcopenia: Prevention and Treatment Options
edited by Steven Phu
submission deadline 20 Jul 2026 | Submission Open
Keywords: sarcopenia; skeletal muscle; ageing; falls; frailty; exercise; rehabilitation; nutrition
(This special issue belongs to the Section Geriatric Medicine)
Current Challenges in Adult Congenital Heart Diseases submission deadline 20 Jul 2026 | Submission Open
Keywords: adult congenital heart disease; quality of life; pregnancy in congenital heart disease; heart failure; arrhythmia; septal defect; congenital valve stenosis; coarctation of the Aorta; Fontan circulation; Tetralogy of Fallot
(This special issue belongs to the Section Cardiology)
Therapeutic Advances in Hematological Malignancies: New Breakthroughs and Future Directions
edited by Seema Naik
submission deadline 20 Jul 2026 | Submission Open
Keywords: leukemia; lymphoma; myeloma; cell therapy; targeted therapy
(This special issue belongs to the Section Hematology)
Clinical Strategies for Preventing Healthcare-Associated Infections submission deadline 24 Jul 2026 | Viewed by 23 | Submission Open
Keywords: healthcare-associated infections; multidrug resistance; prevention; screening scales; polymicrobial infections; oppor-tunistic infections; sepsis
(This special issue belongs to the Section Infectious Diseases)
Recent Clinical Advances in Pelvic Organ Prolapse
edited by José Antonio García-Mejido and José Antonio Sainz-Bueno
submission deadline 24 Jul 2026 | Viewed by 11 | Submission Open
Keywords: pelvic organ prolapse; pelvic floor dysfunction; urogynecology; pelvic reconstructive surgery; pathophysiology of POP; surgical techniques; conservative management; patient-reported outcomes; biomaterials in pelvic surgery; levator ani muscle
(This special issue belongs to the Section Obstetrics & Gynecology)
Psychological Affliction in Pregnancy, Delivery and Postpartum Period: A Multidisciplinary Approach submission deadline 24 Jul 2026 | Submission Open
Keywords: maternal mental health; pregnancy; postpartum depression; perinatal anxiety; midwifery; multidisciplinary care
(This special issue belongs to the Section Mental Health)
Clinical Advances in Spinal Neurosurgery
edited by Jang-Won Yoon
submission deadline 25 Jul 2026 | 2 articles | Viewed by 1939 | Submission Open
Keywords: minimally invasive spine surgery; lateral lumbar interbody fusion; endoscopic spine surgery; patient-reported out-comes; functional assessment; perioperative care; surgical decision-making
(This special issue belongs to the Section Clinical Neurology)
High-Risk Pregnancy Management: From Prenatal Care to Postpartum Outcomes
edited by
submission deadline 25 Jul 2026 | Viewed by 44 | Submission Open
Keywords: high-risk pregnancy; prenatal care; postpartum outcomes; postpartum mental health; birth trauma; AI in obstetrics; medico-legal liability; equity & culturally safe care; indigenous and rural/remote care; EMR-enabled decision support; quality trend monitoring; maternal morbidity and mortality; perinatal morbidity; standardized care bundles & pathways
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Updates on Transcatheter Structural Heart Disease Interventions
edited by Nazan Puluca and Hendrik Ruge
submission deadline 25 Jul 2026 | Viewed by 28 | Submission Open
Keywords: interventional valve therapy; TAVR; TEER; TMVR; mitral valve; tricuspid valve; coronary access
(This special issue belongs to the Section Cardiology)
Current Advances and Future Perspectives in Cardiac Arrest and Cardiogenic Shock
edited by Giulia Maj
submission deadline 25 Jul 2026 | Viewed by 27 | Submission Open
Keywords: cardiogenic shock; left ventricular unloading; biomarkers; recovery; cardiac arrest
(This special issue belongs to the Section Emergency Medicine)
Recent Advance in Bariatric Surgery submission deadline 25 Jul 2026 | Viewed by 20 | Submission Open
Keywords: bariatric surgery; metabolic surgery; minimally invasive surgery; robotic surgery; endoscopic bariatric procedures; obesity management; type 2 diabetes remission; perioperative care; long-term outcomes; enhanced recovery
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Sleep Disorders: Current Research and Future Directions—Second Edition
edited by Martina Vendrame
submission deadline 25 Jul 2026 | Viewed by 20 | Submission Open
Keywords: obstructive sleep apnea; parasomnia; idiopathic hypersomnia; periodic limb movement disorder; periodic limb move-ment of sleep
(This special issue belongs to the Section Clinical Neurology)
Interaction Between Systemic Diseases and Oral Diseases: 2nd Edition
edited by
submission deadline 25 Jul 2026 | Viewed by 13 | Submission Open
Keywords: medical dental interaction; saliva; xerostomia; diagnostics; inflammatory bowel disease; cancer survivors; dental erosion; Sjö gren’ s disease; liver transplantation
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Clinical Application of Endoscopic Submucosal Dissection in Malignant Gastrointestinal Tumors and Precursors—2nd Edition submission deadline 25 Jul 2026 | Viewed by 10 | Submission Open
Keywords: endoscopy; endoscopic submucosal dissection; endoscopic surgery; laparoscopic surgery; minimally invasive surgery
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Hearing Loss Management in Children: Guidelines and Interventions
edited by Lone Percy-Smith
submission deadline 25 Jul 2026 | Viewed by 1 | Submission Open
Keywords: early intervention for populations with HL; emerging new generations of persons with HL; quality assurance of interventions for populations with HL; self-assessments of quality of life
(This special issue belongs to the Section Clinical Pediatrics)
Complications Related to Coronary Artery Disease and Secondary Prevention Strategies
edited by Nazanin Rajai
submission deadline 25 Jul 2026 | Submission Open
Keywords: coronary artery disease; complications; secondary prevention; myocardial infarction; cardiovascular risk; heart failure; arrhythmias; imaging; biomarkers; cardiovascular pharmacotherapy
(This special issue belongs to the Section Cardiovascular Medicine)
Updates in the Diagnosis, Imaging, and Treatment of Retinal and Macular Diseases
edited by
submission deadline 26 Jul 2026 | Viewed by 30 | Submission Open
Keywords: retinal diseases; macular degeneration; diagnostic imaging; OCT/OCTA; artificial intelligence; deep learning; clinical ophthalmology; gene therapy; treatment innovations
(This special issue belongs to the Section Ophthalmology)
Clinical Diagnosis and Treatment Strategies in Sjogren's Disease (SjD)
edited by , and Nancy McNamara
submission deadline 29 Jul 2026 | Submission Open
Keywords: Sjogren; Sjogren’s disease; lymphocytic tissue infiltration; interdisciplinary care; pathogenesis; caries; corneal erosions; autoimmunity; lymphoproliferative (or lymphoma)
(This special issue belongs to the Section Immunology & Rheumatology)
Improving Outcomes in Systemic Lupus Erythematosus: Latest Advances and Prospects in Relation to Comorbidity, Damage, and Quality of Life
edited by and Shaye Kivity
submission deadline 30 Jul 2026 | Viewed by 60 | Submission Open
Keywords: systemic lupus erythematosus; comorbidities; outcome measures; damage accrual; quality of life; cognitive im-pairment; infections and vaccination; treat-to-target; digital biomarkers
(This special issue belongs to the Section Immunology & Rheumatology)
Clinical Insights and Applications in Cardiac Electrophysiology
edited by and Fabrizio Guarracini
submission deadline 30 Jul 2026 | Viewed by 8 | Submission Open
Keywords: atrial fibrillation; catheter ablation; transvenous lead extraction; left atrial appendage occlusion; heart failure; subcutaneous ICD; extravascular ICD; conduction system pacing; cardiac electrophysiology; cardiac rhythm disorders; arrhythmia mapping; supraventricular arrhythmias; ventricular arrhythmias; cardiomyopathies; implantable cardiac devices; minimally invasive devices; left atrial appendage closure; personalized arrhythmia care; clinical management; innovative electrophysiological techniques
(This special issue belongs to the Section Cardiology)
Endoscopic Management of Pancreaticobiliary Diseases
edited by
submission deadline 30 Jul 2026 | Viewed by 6 | Submission Open
Keywords: pancreaticobiliary endoscopy; endoscopic ultrasound (EUS); endoscopic retrograde cholangiopancreatography (ERCP); biliary drainage; gallbladder drainage; lumen-opposing metal stents; cholangioscopy; pancreatoscopy; confocal laser endomicroscopy; pancreatic cysts; molecular diagnostics; lithotripsy (electrohydraulic and laser); radiofrequency ablation (RFA); photodynamic therapy (PDT); pancreatic and biliary tumors; interventional endoscopy; altered anatomy access; diagnostic and therapeutic endoscopy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Application of Physical Therapy in Neurorehabilitation: 3rd Edition submission deadline 31 Jul 2026 | Viewed by 22 | Submission Open
Keywords: physical therapy; technology-aided rehabilitation; exercise; neurorehabilitation; neuroplasticity; engagement; self-management
(This special issue belongs to the Section Clinical Rehabilitation)
The Future Direction of Medical Imaging in Hepato-Bilio-Pancreatic Oncology: Challenges and Opportunities
edited by
submission deadline 31 Jul 2026 | Viewed by 13 | Submission Open
Keywords: MRI; CT; molecular imaging; radiomics; imaging; radiogenomics; precision medicine; outcome prediction; cholangiocarcinoma; pancreatic cancer; imaging biomarkers; treatment response
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Neuro-Psychiatric Disorders: Updates on Diagnosis and Treatment—2nd Edition
edited by
submission deadline 31 Jul 2026 | Viewed by 9 | Submission Open
Keywords: neuropsychiatric disorder; diagnosis; treatment; neurobiology; organic psychiatry
(This special issue belongs to the Section Mental Health)
Breakthroughs in the Treatment of Colorectal Cancer
edited by Laura Fortuna and
submission deadline 31 Jul 2026 | Submission Open
Keywords: colorectal cancer; targeted therapy; minimally invasive surgery; immune– oncology integration; enhanced recovery protocols; multidisciplinary care
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Sports Cardiology: Current Clinical Status and Outlook into the Future
edited by Aakash Bavishi and Matthew W Martinez
submission deadline 10 Aug 2026 | Viewed by 30 | Submission Open
Keywords: sports cardiology; athletes; cardiac imaging; hypertrophic cardiomyopathy; screening; electrocardiogram; electrophysiology; echocardiography; sudden cardiac death
(This special issue belongs to the Section Cardiology)
New Insights into Glaucoma: 2nd Edition
edited by and
submission deadline 10 Aug 2026 | Submission Open
Keywords: glaucoma; intraocular pressure (IOP); risk calculators; glaucoma screening glaucoma surgery; cataract surgery; trabeculectomy; glaucoma drainage devices; minimally invasive glaucoma surgery (MIGS); artificial intelligence (AI)
(This special issue belongs to the Section Ophthalmology)
Neurovascular Canvas: From Basic Science to Clinical Breakthroughs
edited by , Nicola Giannini and
submission deadline 15 Aug 2026 | Viewed by 43 | Submission Open
Keywords: neurovascular unit (NVU); neurodegeneration; vascular biology; stroke; disease modeling
(This special issue belongs to the Section Clinical Neurology)
Current Trends and Innovations in Coronary Artery Disease and Myocardial Ischemia: Second Edition
edited by
submission deadline 20 Aug 2026 | Viewed by 49 | Submission Open
Keywords: coronary artery disease; fractional flow reserve; invasive coronary angiography; cardiac CT; cardiac MRI
(This special issue belongs to the Section Cardiovascular Medicine)
New Insights into Gastrointestinal Surgery: Advances in Techniques and Treatment Approaches
edited by Gabriella Teresa Capolupo
submission deadline 20 Aug 2026 | Viewed by 21 | Submission Open
Keywords: gastroenterology; gastrointestinal surgery; colorectal surgery; robotic surgery; technologies; minimally invasive surgery
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Current and Emerging Strategies in Ischemic Stroke: Diagnosis, Treatment, and Prevention submission deadline 25 Aug 2026 | Submission Open
Keywords: diagnosis; digital medicine; epidemiology; ischemic stroke; machine learning; neurorehabilitation; prevention; stroke imaging; treatment
(This special issue belongs to the Section Clinical Neurology)
Optimizing the Surgical Journey: From Abdominal Operation to Recovery
edited by and Carlo Bergamini
submission deadline 1 Sep 2026 | Viewed by 12 | Submission Open
Keywords: surgical complications; comanagement; comorbidities; elective surgical procedure; emergency surgery procedure; multidisciplinary approach; hospitalist
(This special issue belongs to the Section General Surgery)
Current Challenges in Clinical Dentistry: 3rd Edition
edited by and
submission deadline 15 Sep 2026 | Viewed by 19 | Submission Open
Keywords: artificial intelligence; clinical dentistry; cutting-edge device and technology; dental material; challenging hypothesis; preventive dentistry; sleep medicine; digital dentistry; smart dentistry; stomatognathic function
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Treatment and Clinical Management of Necrotizing Pancreatitis submission deadline 20 Sep 2026 | Viewed by 8 | Submission Open
Keywords: necrotizing pancreatitis; infected necrosis; step-up approach; necrosectomy; minimally invasive surgery; artificial intelligence; lumen-apposing metal stent; pancreatic necrosis
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Management in Dry Eye Disease: Current Strategies and Emerging Protocols
edited by Sunil Shah and Raquel Gil-Cazorla
submission deadline 20 Sep 2026 | Submission Open
Keywords: dry eye disease; ocular surface; diagnostics; inflammation; biomarkers; emerging therapies
(This special issue belongs to the Section Ophthalmology)
Advances in the Diagnosis and Management of Sarcoidosis
edited by , Pilar Brito-Zerón and Miriam Akasbi Montalvo
submission deadline 25 Sep 2026 | Submission Open
Keywords: sarcoidosis; diagnosis; biomarkers; imaging; immunopathogenesis; biologic therapy; prognosis; interstitial lung disease
(This special issue belongs to the Section Immunology & Rheumatology)
Fibromyalgia: Diagnostic Progress and Therapeutic Advances submission deadline 17 Nov 2026 | Viewed by 13 | Submission Open
Keywords: fibromyalgia; chronic pain; central sensitization; diagnostic biomarkers; advanced imaging; molecular markers; autonomic nervous system; cardiovascular regulation; emotional processing; cognitive dysfunction; fatigue; pain modulation; neuromodulation; tDCS
(This special issue belongs to the Section Clinical Neurology)
Dental Care: Oral and Systemic Disease Prevention: 2nd Edition
edited by
submission deadline 31 Dec 2026 | 1 articles | Viewed by 1333 | Submission Open
Keywords: oral health; oral diseases; oral manifestations; systemic diseases; oral care; dental prevention; dental caries; periodontal disease; oral medicine; dentistry; oral microbiome; salivary diagnostics; AI-assisted tools
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Aortic Diseases: Modern Strategies in Diagnosis, Management, and Prevention of Complications
edited by , Tilo Kölbel and José Ignacio F. Torrealba
submission deadline 20 Jul 2027 | Viewed by 113 | Submission Open
Keywords: aortic aneurysm; aortic dissection; genetic aortic disease; acute aortic syndromes; endovascular repair; complica-tions; outcomes
(This special issue belongs to the Section Vascular Medicine)
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