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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Erythrocyte Cell Death: Molecular Insights

edited by

Anton Tkachenko

submission deadline 20 Jul 2025 | 2 articles | Viewed by 2233 | Submission Open

Keywords: cell death signaling; eryptosis; erythrocyte senescence; erythrocytes; necroptosis; regulated cell death

(This special issue belongs to the Section Molecular Biology)

Prostate Cancer Research Update: Molecular Diagnostic Biomarkers

edited by Mikhail Baryshev

submission deadline 20 Jul 2025 | 2 articles | Viewed by 2230 | Submission Open

Keywords: prostate cancer; molecular biomarkers; cancer-specific DNA methylation; non-coding genes; gene fusions; lncRNA

(This special issue belongs to the Section Molecular Oncology)

Stem Cells in Health and Disease: 3rd Edition

edited by

Maja Ludvigsen

submission deadline 20 Jul 2025 | 2 articles | Viewed by 2220 | Submission Open

Keywords: stem cell regulation; differentiation; pluripotency; reprogramming; stem cell therapy; cancer stem cell/tumor-initiating cell; therapy resistance; regenerative medicine; metabolic plasticity

(This special issue belongs to the Section Molecular Biology)

New Advances in Nanomedicine Innovation in Cancer Treatment

edited by Tijani Gharbi

submission deadline 20 Jul 2025 | 2 articles | Viewed by 2216 | Submission Open

Keywords: nanotechnology; nanomedicine; radiotherapy; theragnostic; antibody– drug conjugates (ADCs); drug delivery; radiopharmaceutical; gold nanoparticles; nanoparticle– biomolecule conjugate

(This special issue belongs to the Section Molecular Nanoscience)

Molecular Mechanisms and Therapies of Hematological Tumors

edited by

Maria Teresa Bochicchio

and

Giorgia Simonetti

submission deadline 20 Jul 2025 | 2 articles | Viewed by 2207 | Submission Open

Keywords: genetic alterations; next-generation sequencing; molecular biomarkers; target therapy; drug resistance

(This special issue belongs to the Section Molecular Oncology)

Molecular Biology and Targeted Therapies in Leukemias

edited by Fabio Stagno and

Stefania Stella

submission deadline 20 Jul 2025 | 2 articles | Viewed by 2195 | Submission Open

Keywords: molecular biology; target therapy; leukemia; TKI; BCL-2; FLT3; CAR-T cells; CML

(This special issue belongs to the Section Molecular Oncology)

Insights into Mitochondrial Iron Metabolism: Connections to Cancer and Other Pathologies

edited by Michael Petronek

submission deadline 20 Jul 2025 | 1 articles | Viewed by 2165 | Submission Open

Keywords: iron metabolism; mitochondrial iron; cellular homeostasis; iron– sulfur cluster biogenesis; heme synthesis; mitochondrial ferritin; cancer biology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular and Genetic Studies on Tourette Syndrome and Comorbid Disorders

edited by Jakub P. Fichna and Natalia Szejko

submission deadline 20 Jul 2025 | 1 articles | Viewed by 2134 | Submission Open

Keywords: Tourette syndrome; genetics and genomics; molecular neurobiology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

G Protein-Coupled Receptor Drug Discovery: Recent Advances and Future Perspectives

edited by Boshi Huang and

Dongwei Kang

submission deadline 20 Jul 2025 | 2 articles | Viewed by 2131 | Submission Open

Keywords: GPCR drug discovery; GPCR therapeutics; drug design and synthesis; structural biology; preclinical evaluation

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Mechanisms of Bone Development and Differentiation in Health and Disease

edited by

Cristina Sánchez-De-Diego

submission deadline 20 Jul 2025 | 2 articles | Viewed by 2100 | Submission Open

Keywords: bone differentiation; signaling pathways; bone diseases; bone formation; osteoblast; osteocyte; osteoclast

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Inflammation in Atherosclerosis: Current Advances

edited by Tuva B. Dahl

submission deadline 20 Jul 2025 | 1 articles | Viewed by 2099 | Submission Open

Keywords: inflammation; atherosclerosis; cardiovascular disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Nucleic Acid Recognition and Pharmaceutical Ligand Design

edited by

Marijana Radić Stojković

and

Atanas Kurutos

submission deadline 20 Jul 2025 | 1 articles | Viewed by 2078 | Submission Open

Keywords: nucleic acid recognition; ligand design; analytical techniques; computational chemistry; therapeutics

(This special issue belongs to the Section Macromolecules)

The Discovery, Extraction, Synthesis, and Application of Natural Products

edited by

Hah Young Yoo

, Kang Hyun Lee and

Taek Lee

submission deadline 20 Jul 2025 | 2 articles | Viewed by 2033 | Submission Open

Keywords: antibiotics; antioxidants; biomass; bioactive molecule; biological activity; biosynthesis; biosensor; biomedicine; biotechnology

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Biology of Liver Diseases: Pathogenesis, Diagnostics and Treatment

edited by

Rosaria Maria Pipitone

and Stefania Grimaudo

submission deadline 20 Jul 2025 | 1 articles | Viewed by 1954 | Submission Open

Keywords: non-alcoholic fatty liver disease; steatosis; fibrogenesis; hepatocellular carcinoma; hepatocytes; hepatic stellate cells; inflammation; oxidative stress; efferocytosis; apoptosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Pathology and Treatment of Spinal Cord Injury

edited by James Hong

submission deadline 20 Jul 2025 | 1 articles | Viewed by 1953 | Submission Open

Keywords: spinal cord injury; neuroinflammation; gene targets; neural regeneration; synaptic plasticity; molecular pathways; biomarkers; oxidative stress; apoptosis; translational research

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Insight into Skin Infection and Inflammation

edited by

Danuta Nowicka

submission deadline 20 Jul 2025 | 1 articles | Viewed by 1948 | Submission Open

Keywords: skin infection; skin inflammation; inflammatory skin diseases; atopic dermatitis; skin microbiome

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Advances in the Treatment and Diagnosis of Neuromuscular Diseases

edited by Silvia Consalvi

submission deadline 20 Jul 2025 | 1 articles | Viewed by 1915 | Submission Open

Keywords: neuromuscular diseases; gene therapies; stem cell therapy; treatment and diagnosis

(This special issue belongs to the Section Molecular Neurobiology)

How Aging Results in Cognitive Decline: Molecular Mechanisms

edited by Holly Christian Hunsberger

submission deadline 20 Jul 2025 | 1 articles | Viewed by 1804 | Submission Open

Keywords: aging; memory; hippocampus; neurodegeneration; sex; gender; exercise; synapses; metabolism; mitochondria

(This special issue belongs to the Section Molecular Neurobiology)

Oxidative Stress in Dermatology, Aesthetics and Regenerative Medicine

edited by

Eugenio Luigi Iorio

submission deadline 20 Jul 2025 | Viewed by 1734 | Submission Open

Keywords: oxidative stress; redox system; antioxidant chemical species; dermatology; aesthetics; regenerative medicine; inflammatory; degenerative skin diseases

(This special issue belongs to the Section Molecular Biology)

Molecular Biology of Lung Cancer: From Intrinsic to Acquired Resistance Mechanisms

edited by

Federico Pio Fabrizio

submission deadline 20 Jul 2025 | 1 articles | Viewed by 1724 | Submission Open

Keywords: lung cancer; NSCLC; cancer therapy; resistance; DNA methylation

(This special issue belongs to the Section Molecular Oncology)

Molecular Advances in Neurologic and Neurodegenerative Disorders

edited by

Ioana-Miruna Balmus

and

Ioannis Mavroudis

submission deadline 20 Jul 2025 | 2 articles | Viewed by 1716 | Submission Open

Keywords: traumatic brain injury; chronic traumatic encephalopathy; Alzheimer’ s disease; motor neuron disease; amyotrophic lateral sclerosis; neurosignalling; neurodegeneration; brain– gut axis impairment; oxidative stress; chronic inflammation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms of Genetic Variants of Parkinson’s Disease

edited by Michael Schlossmacher and

Ari Zimran

submission deadline 20 Jul 2025 | 2 articles | Viewed by 1707 | Submission Open

Keywords: DNA; PD prevention; genetic variants of Parkinson's disease

(This special issue belongs to the Section Molecular Neurobiology)

Progress in the Use of Graphene and Graphene-Like Materials in Various Applications

edited by Piotr Kamedulski

submission deadline 20 Jul 2025 | 2 articles | Viewed by 1685 | Submission Open

Keywords: graphene; porous carbons; carbon-based materials; 3D graphene; graphene exfoliation; nanotubes; nanomaterials; N-rich nano-porous carbon matrixes; N-rich activated carbons; carbon molecular sieves; hybrid materials; medical applications

(This special issue belongs to the Section Materials Science)

Neurodegeneration and Neuroinflammatory Processes in Age-Related Diseases

edited by

Barbara Mroczko

submission deadline 20 Jul 2025 | 2 articles | Viewed by 1679 | Submission Open

Keywords: age-related diseases; neurodegenerative diseases; neurodegeneration; neuroinflammation; aging

(This special issue belongs to the Section Molecular Neurobiology)

Pathogenesis and Molecular Treatment of Primary Liver Cancer

edited by

Diego F. Calvisi

submission deadline 20 Jul 2025 | 1 articles | Viewed by 1671 | Submission Open

Keywords: primary liver cancer; cholangiocarcinoma; hepatocellular carcinoma; hepatoblastoma; molecular pathogenesis; targeted therapies; anticancer drug

(This special issue belongs to the Section Molecular Oncology)

Exploring New Field in Hydrocolloids Research and Applications

edited by

Mihaela Violeta Ghica

, Cristina Elena Dinu-Pirvu and

Lacramioara Popa

submission deadline 20 Jul 2025 | 1 articles | Viewed by 1637 | Submission Open

Keywords: drug delivery systems; controlled-release; targeted delivery; wound healing; tissue engineering; bioadhesive agents; transdermal patches; mucoadhesive hydrogels; ophthalmic preparations; oral disintegrating films; gastroretentive systems; rheology modifiers; textural characteristics; stabilizing agents; encapsulation for protection and stability (drugs; probiotics and bioactive compounds); 3D bioprinting; nutraceutical delivery

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Advanced Oxidation Processes for the Decontamination of Emerging Contaminants and Disinfection of Pathogenic Microorganisms

edited by

Chengdu Qi

submission deadline 20 Jul 2025 | 1 articles | Viewed by 1599 | Submission Open

Keywords: advanced oxidation processes; emerging contaminants; pathogenic microorganisms; disinfection; hydroxyl radical; sulfate radical; organic radical

(This special issue belongs to the Section Molecular Microbiology)

Pigment Cells: From Biology to Medicine

edited by

Jakub Rok

submission deadline 20 Jul 2025 | 2 articles | Viewed by 1595 | Submission Open

Keywords: melanin; melanocyte; melanogenesis; melanoma; melanosome; neuromelanin; photoprotection; oxidative stress; phototoxicity; pigmentation disorders; drug– melanin complexes; skin cancer; UV radiation; retinal pigment epithelium

(This special issue belongs to the Section Molecular Biology)

New Molecular Insights and Therapeutic Strategies for Ocular Vascular Pathologies

edited by Raquel Lima e Silva

submission deadline 20 Jul 2025 | 1 articles | Viewed by 1566 | Submission Open

Keywords: VEGF pathway; anti-VEGF therapy; retinal neovascularization; choroidal neovascularization; oxidative stress

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Melatonin Treatment in Diseases: From Clinical Application Research to Targeted Drug

edited by

Rita Rezzani

submission deadline 20 Jul 2025 | 1 articles | Viewed by 1533 | Submission Open

Keywords: health and pathology; oxidative stress and inflammation; endothelial dysfunction; aging and cancer; skin diseases; gastrointestinal disorders; neurodegenerative and cardiovascular diseases; microbiota composition and function; brain-gut axis; metabolic syndromes; sex/gender dimorphism

(This special issue belongs to the Section Molecular Biology)

Molecular Mechanisms: New Insights into the Pathogenesis of Neonatal Disorders

edited by

Rozeta Sokou

submission deadline 20 Jul 2025 | 1 articles | Viewed by 1498 | Submission Open

Keywords: neonate; neonatal infections; molecular and cellular mechanisms; necrotizing enterocolitis; immature immune system; neonatal inflammation; epigenetic modification; regulatory RNAs; bronchopulmonary dysplasia; neonatal hypoxic– ischemic injury

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Micro(nano) Plastics and Estrogens as Endocrine Disruptors Meet the Female Reproductive System, Breast and Colon: What Is Going On?

edited by

Anna Maria Giuseppina Poma

submission deadline 20 Jul 2025 | 1 articles | Viewed by 1490 | Submission Open

Keywords: micro(nano) plastics; estrogens; endocrine disruptors; female reproductive system; breast; colon

(This special issue belongs to the Section Molecular Biology)

The Role and Mechanisms of Natural Products in Inflammatory Responses and Inflammatory Diseases

edited by

Young-Su Yi

submission deadline 20 Jul 2025 | 1 articles | Viewed by 1481 | Submission Open

Keywords: natural product; bioactive component; inflammation; inflammatory disease; anti-inflammatory; mechanism

(This special issue belongs to the Section Molecular Immunology)

Molecular Targets in Gastrointestinal Diseases

edited by

Changwon Yang

submission deadline 20 Jul 2025 | 1 articles | Viewed by 1471 | Submission Open

Keywords: molecular pathways; gastrointestinal cancers; inflammatory bowel disease; targeted therapies; microbiota; gene editing

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Natural Compounds: Structural Diversity, Modifications, and Biological Activities

edited by Tomasz Pospieszny

submission deadline 20 Jul 2025 | 2 articles | Viewed by 1391 | Submission Open

Keywords: bile acids; molecular research; biological activity; natural products; steroids

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Recent Research of Nanomaterials in Molecular Science: 2nd Edition

edited by

Giovanna Iezzi

submission deadline 20 Jul 2025 | 3 articles | Viewed by 1351 | Submission Open

Keywords: nanomaterials; medical research; synthesis and characterization; molecular formula; molecular dynamics; molecular imaging; cell signaling; cellular metabolism; tissue regeneration; biocompatibility; molecular biology; nanomedicine; functional nanomaterials; drug and gene delivery; tissue engineering; cancer therapy

(This special issue belongs to the Section Molecular Nanoscience)

Interplay of Metabolism and Inflammation in Gastrointestinal Disease

edited by Marios Papadakis and

Stavros P. Papadakos

submission deadline 20 Jul 2025 | Viewed by 1302 | Submission Open

Keywords: gastrointestinal diseases; inflammation; metabolic dysregulation; metabolic processes

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms and Signaling Pathways in Alzheimer’s Disease

edited by

Alberto Ouro

submission deadline 20 Jul 2025 | 1 articles | Viewed by 1284 | Submission Open

Keywords: Alzheimer’ s disease; aging; β -amyloid; biomarkers; cell signaling; tau; mitochondrial dysfunction; neuroinflammation; vascular alterations

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Research on Pharmacogenetics

edited by

Stefania Cheli

submission deadline 20 Jul 2025 | 1 articles | Viewed by 1216 | Submission Open

Keywords: pharmacogenetics; pharmacokinetics; pharmacodynamics; genotype; haplotype; biomarker; single-nucleotide polymorphism; genomic variant; genetic testing; adverse drug reactions; clinical implementation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Neurogenetics: Applications of Precision Medicine and Gene Therapy for Rare Neurogenetic Disorders

edited by

Paschalis Theotokis

submission deadline 20 Jul 2025 | 1 articles | Viewed by 1209 | Submission Open

Keywords: precision medicine; gene therapy; neurogenetics; rare monogenic diseases; inherited nervous system disorders; mitochondrial diseases (e.g.; LHON; MELAS); lysosomal storage disorders (e.g.; Tay– Sachs; Gaucher); hereditary neuropathies (e.g.; CMT; hATTR); motor neuron diseases (e.g.; SMA; ALS); spinocerebellar ataxias (e.g.; SCA); biomarkers in neurology

(This special issue belongs to the Section Molecular Neurobiology)

Lipid Droplet Proteins Function and Metabolism

edited by

Vitor Teixeira

submission deadline 20 Jul 2025 | 1 articles | Viewed by 1185 | Submission Open

Keywords: lipid droplets; LD protein; LD metabolism

(This special issue belongs to the Section Biochemistry)

Molecular Research on Tumor Suppressor Proteins

edited by Jie Liu

submission deadline 20 Jul 2025 | 1 articles | Viewed by 1063 | Submission Open

Keywords: DNA repair; genome stability; tumor suppressor; BRCA1; BRCA2; PALB2; RAD51C

(This special issue belongs to the Section Molecular Oncology)

The 50th Anniversary of the Discovery of Reciprocal Translocation between Chromosome 9 and 22: The Impact on Molecular and Genomic Knowledge on Cancer

edited by

Ana Cristina Gonçalves

Raquel Alves

and

Ana Bela Sarmento Ribeiro

submission deadline 20 Jul 2025 | 1 articles | Viewed by 1063 | Submission Open

Keywords: cancer genomics; cancer biomarkers; cancer pathogenesis; precision oncology

(This special issue belongs to the Section Molecular Oncology)

How Melanin Affects the Therapy Response of Cutaneous Melanoma?

edited by

Elena Andreucci

submission deadline 20 Jul 2025 | Viewed by 1027 | Submission Open

Keywords: cutaneous melanoma; melanin; hyperpigmentation; tyrosinase; therapy resistance; molecular medicine; new therapeutic targets

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Fibrotic Disease: From Pathophysiology to Treatment

edited by Galina S. Bogatkevich

submission deadline 20 Jul 2025 | Viewed by 1007 | Submission Open

Keywords: lung; liver; heart; kidney; fibrosis; systemic sclerosis; mechanisms; pathophysiology; therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research in Redox Balance in Pathological and Physiological Conditions

edited by

Pawel Sutkowy

submission deadline 20 Jul 2025 | 1 articles | Viewed by 981 | Submission Open

Keywords: oxidative stress; nitrosative stress; antioxidative stress; redox signaling; inflammation; antioxidants; reactive oxygen species; reactive nitrogen species; pathological states; physiological condition

(This special issue belongs to the Section Molecular Biology)

New Insights in Bacterial Infection Research: From Mechanisms to Therapies

edited by Marcin Równicki and

Tania Silva

submission deadline 20 Jul 2025 | Viewed by 973 | Submission Open

Keywords: bacteria; infection; antibiotic resistant; bacterial persisters; antimicrobial therapies; host-pathogen interactions

(This special issue belongs to the Section Molecular Microbiology)

Recent Advances in Nanomedicines Against Bacterial Infections

edited by

Stephanie Andrade

, Nuno Guimarães,

Maria João Ramalho

and

Joana A. Loureiro

submission deadline 20 Jul 2025 | Viewed by 960 | Submission Open

Keywords: nanotechnology; nanoparticle; nanocarriers; nanoantibiotic; drug delivery system; targeted delivery; theranostic; infectious diseases; antibacterial agent; antimicrobial resistance; biomedical application

(This special issue belongs to the Section Molecular Nanoscience)

Cell Envelope Biogenesis and, Molecular Strategies to Maintain Cellular Homeostasis in Bacteria

edited by

Satish Raina

and

Gracjana Klein

submission deadline 20 Jul 2025 | 1 articles | Viewed by 838 | Submission Open

Keywords: LpxC and the regulation of LPS; periplasmic protein folding; disulfide bond formation; BAM proteins and assembly of outer membrane proteins; periplasmic protease DegP (HtrA); lipopolysaccharide assembly; LPS modifications and diversity; LPS and phospholipid trafficking; bacterial virulence factors; antibiotic resistance; extracytoplasmic function sigma factors; regulatory RNAs; two-component systems; lipid A and its modification

(This special issue belongs to the Section Molecular Microbiology)

New Insights and Research on Nutrition and Obesity

edited by

Giovanna Bermano

submission deadline 20 Jul 2025 | 1 articles | Viewed by 821 | Submission Open

Keywords: nutrition; obesity; malnutrition; overnutrition; molecular and cellular mechanisms; nutrient– gene interactions; metabolic disorders

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Displaying special issue 351-400 on page 8 of 68.

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