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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Genetic Mutations in Health and Disease

edited by

Eva Bagyinszky

submission deadline 26 May 2025 | 6 articles | Viewed by 7178 | Submission Open

Keywords: genetic diseases; mutations; genetic screening; structure prediction; haploinsufficeincy; germline mutations; somatic mutations; gene enviroment interaction; gene-gene interations

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Pharmacological Advances in Gastrointestinal Health

edited by

Mirjana Stupnisek

submission deadline 26 May 2025 | Viewed by 232 | Submission Open

Keywords: gastrointestinal disorders; gastrointestinal healing; gut microbiota; inflammatory bowel disease; irritable bowel syndrome; gastrointestinal cancer; Crohn’ s disease; metabolic syndrome; cytoprotective agents; nonsteroidal anti-inflammatory drugs’ toxicity

(This special issue belongs to the Section Molecular Pharmacology)

Cardiovascular Diseases: Molecular Mechanisms and Potential Therapy (2nd Edition)

edited by

Andrea Ghiroldi

submission deadline 26 May 2025 | Viewed by 202 | Submission Open

Keywords: cardiovascular diseases; pathogenic mechanisms; genetics; cardiomyopathy; myocardial infarction; cardiac fibrosis; pharmacogenomics; drug discovery

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Latest Molecular and Psycho-Physiological Insights on “Brain Fatigue”

edited by

Takehiko Fujino

and

Masanori Honsho

submission deadline 27 May 2025 | Viewed by 136 | Submission Open

Keywords: epigenetics; neurotransmitter including dopamine; mitochondria dysfunction; neuroinflammation; lipidomics including plasmalogen; proteomics including neuropeptide; neural network; cognition abilities; decline in attention; judgement capacity; depressive state

(This special issue belongs to the Section Molecular Neurobiology)

Bacteria-Mediated Cancer Therapy: New Molecular Insights

edited by

Che-Hsin Lee

submission deadline 27 May 2025 | Viewed by 131 | Submission Open

Keywords: bacteria-mediated cancer therapy; tumor microenvironment (TME); tumour immunotherapy; anticancer bacteria

(This special issue belongs to the Section Molecular Oncology)

Recent Developments in Molecular Genetic Breeding of Forest Trees

edited by

Su Chen

submission deadline 28 May 2025 | 1 articles | Viewed by 814 | Submission Open

Keywords: tree genetics; tree breeding; molecular breeding; genetic improvement

(This special issue belongs to the Section Molecular Plant Sciences)

Serotonin in Health and Diseases

edited by

Elena E. Voronezhskaya

submission deadline 29 May 2025 | 6 articles | Viewed by 10449 | Submission Open

Keywords: components of serotonergic system; serotonin targets; related systems; serotonergic mechanisms; experimental models

(This special issue belongs to the Section Biochemistry)

Parasite Biology and Host-Parasite Interactions: 2nd Edition

edited by

Michael Stear

and

Katarzyna Donskow-Lysoniewska

submission deadline 30 May 2025 | 12 articles | Viewed by 21602 | Submission Open

Keywords: parasite; immunity; immunomodulation; helper T cells; IgA; IgE; eosinophils; mast cells; regulatory T cells; galectin

(This special issue belongs to the Section Molecular Biology)

Microorganisms in the Environment

edited by

Diby Paul

and

Udai B. Singh

submission deadline 30 May 2025 | 4 articles | Viewed by 18182 | Submission Open

Keywords: Environmental microbiology; Bioremediation; Microbial biofilm; Plant– Microbe Interaction

(This special issue belongs to the Section Molecular Microbiology)

Regulation by Non-Coding RNAs 2025

edited by

Won-Ha Lee

submission deadline 30 May 2025 | 6 articles | Viewed by 7148 | Submission Open

Keywords: lncRNAs; circRNAs; miRNAs

(This special issue belongs to the Section Molecular Biology)

Recent Advances in Pathophysiology and Immunology Related to SARS-CoV-2 Infection

edited by

Vito D’Agnano

submission deadline 30 May 2025 | 5 articles | Viewed by 7105 | Submission Open

Keywords: SARS-CoV-2; COVID-19; immunology; pathophysiology; immunopathology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Trends in Allergy and Autoimmunity: Pathogenesis, Biomarkers, and Treatment

edited by

Ilaria Mormile

submission deadline 30 May 2025 | 4 articles | Viewed by 7066 | Submission Open

Keywords: allergy; autoimmunity; autoimmune diseases; asthma; allergic rhinitis; urticaria; inflammation; molecular pathway; biomarkers; target therapy

(This special issue belongs to the Section Molecular Immunology)

Targeting Collagen-Related Therapy

edited by Fernando Revert

submission deadline 30 May 2025 | 3 articles | Viewed by 5860 | Submission Open

Keywords: collagen; extracellular matrix; molecular target; tissue engineering; drug deliver

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Properties and Applications of Nanoparticles and Nanomaterials: 2nd Edition

edited by Xiaogang Li

submission deadline 30 May 2025 | 5 articles | Viewed by 5190 | Submission Open

Keywords: nanostructures; nanoparticles; microstructure characterization; material design; evaluation of mechanical properties; applications of nanomaterials

(This special issue belongs to the Section Molecular Nanoscience)

Antifungal Drug Design, Synthesis and Molecular Mechanisms

edited by Zhibing Wu

submission deadline 30 May 2025 | 2 articles | Viewed by 3469 | Submission Open

Keywords: fungal diseases; antifungal compounds/agents; natural products; computer-aided drug design; synthetic compounds; mechanism of action; fungal disease management strategies

(This special issue belongs to the Section Molecular Informatics)

Recent Advances in Molecular Breeding for Drought and Salt Stress Tolerance in Crops: 2nd Edition

edited by

Zhaoshi Xu

submission deadline 30 May 2025 | 4 articles | Viewed by 3400 | Submission Open

Keywords: drought; salt; heat; cold; gene regulation; genomic research; multiomics; epigenetics; stress signal transduction

(This special issue belongs to the Section Molecular Plant Sciences)

Hepatitis Viruses and Hepatocellular Carcinoma: Research, Treatment and Challenges

edited by

Boyan Grigorov

submission deadline 30 May 2025 | 1 articles | Viewed by 3171 | Submission Open

Keywords: HBV; HDV; HCV; virus replication and pathogenesis; antivirals; virus– cell interaction; vaccine development; hepatocellular carcinoma

(This special issue belongs to the Section Molecular Immunology)

Seed Reserve Mobilization: Unveiling Cellular and Molecular Mechanisms

edited by

Raquel Iglesias Fernandez

submission deadline 30 May 2025 | 1 articles | Viewed by 3164 | Submission Open

Keywords: seed germination; reserve mobilization; vesicle trafficking; protein storage vacuoles (PSVs); oleosomes; seed storage tissues (endosperm; perisperm; cotyledon)

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Research on Inflammatory Diseases of the Gut in Humans and Animals

edited by

Kostas A. Triantaphyllopoulos

submission deadline 30 May 2025 | 1 articles | Viewed by 2811 | Submission Open

Keywords: gene; epigenetic; biomarker; intestinal; gut; IBD; mycobacterium avium; Johne’ s disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Molecular Pathophysiology of Diabetes, Hypertension and Cardiovascular Diseases

edited by Alessandro Durante

submission deadline 30 May 2025 | 1 articles | Viewed by 2443 | Submission Open

Keywords: diabetes; hypertension; cardiology; cardiovascular diseases; coronary artery diseases; athero-sclerosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms of Musculoskeletal Involvement in Rare Diseases

edited by

Gianluigi Pasta

submission deadline 30 May 2025 | 1 articles | Viewed by 2117 | Submission Open

Keywords: rare diseases; molecular pathways; musculoskeletal system; bone involvement; joint degeneration

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms of Dietary Compounds in Cancer Management

edited by

Maria Magdalena Mocanu

and

Alexandru Filippi

submission deadline 30 May 2025 | 1 articles | Viewed by 2029 | Submission Open

Keywords: dietary compounds; cancer prevention; cancer therapy; signaling pathways; heterogeneity; multidrug resistance; cancer stem cells; genetic modifications in cancer; cancer and inflammation; viral infection in cancer; tumor microenvironment

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Mitochondrial Function and Dynamics During Malignant Transformation

edited by Aleksandr Klepinin

submission deadline 30 May 2025 | 1 articles | Viewed by 1875 | Submission Open

Keywords: AMPK; phosphotransfer network; mitochondria; cancer metabolism; glycolysis; metabolic plasticity; cancer cell migration; molecular oncology; cancer treatment strategy

(This special issue belongs to the Section Biochemistry)

Advanced Research of Mitochondria-Targeted Antioxidants

edited by

Pavel A. Nazarov

submission deadline 30 May 2025 | 1 articles | Viewed by 1674 | Submission Open

Keywords: antioxidants; mitochondria; biofilm; bacteria; yeast; aging; tumor; inflammation; bioenergetics; OXPHOS; metabolism

(This special issue belongs to the Section Molecular Biology)

Bioinformatics and Machine Learning for Predicting Biological Processes

edited by Hao Lv

submission deadline 30 May 2025 | 1 articles | Viewed by 1594 | Submission Open

Keywords: bioinformatics; machine learning; multi-omics integration; gene regulation; biological processes; disease processes; data-driven discovery

(This special issue belongs to the Section Molecular Informatics)

Molecular Tools for the Development of Fermented Functional Foods Enriched with Bioactive Compounds

edited by Susana Langa,

Jose Antonio Curiel

and José María Landete

submission deadline 30 May 2025 | 1 articles | Viewed by 1430 | Submission Open

Keywords: molecular tools; fermentation; lactic acid bacteria; yeast; fungi; recombinant enzymes; probiotic; prebiotic; polyphenols; vitamins; food by-product valorization; bioactive compounds; antioxidant; anti-hypertensive; anti-carcinogenic; antimicrobial; anti-aging; food and beverages; GABA

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Therapeutic Potential of Natural Compounds: Insights into Mechanisms, Molecular Docking, and Biological Activities, 2nd Edition

edited by

Rafał Hałasa

and

Katarzyna Turecka

submission deadline 30 May 2025 | 3 articles | Viewed by 1268 | Submission Open

Keywords: natural compounds; synthetic derivatives of natural compounds; biological activity; mechanism of action; molecular docking; therapeutic potential; anticancer; antimicrobial; antiviral; anti-civilization diseases; antiobesity; antidiabetes; preventing the development of cardiovascular diseases; including myocardial infarction; hypertension and ischemic heart disease; food hypersensitivity; antiallergy

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Regulatory Mechanisms of Development and Abiotic Stress Response by Transcriptional Regulators in Plants: 2nd Edition

edited by

Yong-Hwan Moon

submission deadline 30 May 2025 | 1 articles | Viewed by 1070 | Submission Open

Keywords: transcriptional regulator; transcription activation; transcription factor; transcription repression; plant development; abiotic stress response; epigenetic regulation; genome-wide analysis

(This special issue belongs to the Section Molecular Plant Sciences)

Therapeutic Potential of Antioxidants in the Prevention of Human Diseases, 2nd Edition

edited by

Kota V. Ramana

submission deadline 30 May 2025 | 1 articles | Viewed by 966 | Submission Open

Keywords: antioxidants; vitamins; inflammation; cancer; neurological complications; diabetes; flavonoids; natural compounds; cancer; infections; COVID-19

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Virus Infection and Infectious Diseases: Unraveling Mechanisms, Innovations and Therapeutic Strategies—Second Edition

edited by Jung-Hyun Lee

submission deadline 30 May 2025 | 2 articles | Viewed by 936 | Submission Open

Keywords: mechanism of virus infection; host immune responses; innovations in diagnostics and surveillance; therapeutic strategies; epidemiology and global health; data science for infectious disease; zoonotic transmission; virus evolution

(This special issue belongs to the Section Molecular Immunology)

Advances in Secondary Metabolites in Plants

edited by

Sławomir Dresler

submission deadline 30 May 2025 | 1 articles | Viewed by 804 | Submission Open

Keywords: specialized metabolites; biosynthesis pathways; pharmacological applications; medicinal plants; plant stress resistance; abiotic and biotic elicitors; chemometric analysis; plant biotechnology; therapeutic potential; plant signaling and communication

(This special issue belongs to the Section Molecular Plant Sciences)

Phytochemicals of Natural Products: Source, Analysis, and Bioactivities

edited by

Yu-Kuo Chen

, Chi-I Chang and Chi-Chien Lin

submission deadline 30 May 2025 | 1 articles | Viewed by 743 | Submission Open

Keywords: phytochemicals; bioactive compounds; natural products; bioactivities; purification; chemoprevention; chemotherapy

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Recent Advances in Male Reproductive Physiology, Pathophysiology, and Contraception

edited by Gustavo G. Blanco

submission deadline 30 May 2025 | 1 articles | Viewed by 723 | Submission Open

Keywords: spermatogenesis; spermiogenesis; testis; epididymis; sperm function; sperm motility; sperm capacitation; acrosome reaction; male reproduction; male fertility; male infertility; male contraception

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Gene Editing from Bench to Bedside and Back

edited by Daniel Rosenblum

submission deadline 30 May 2025 | Viewed by 643 | Submission Open

Keywords: gene editing; base editing; RNA therapeutics; CRISPR/Cas9; in vivo delivery; molecular medicine

(This special issue belongs to the Section Biochemistry)

Recent Research in Probiotic Yeasts: Molecular Aspects

edited by

Maurizio Ciani

and Francesca Comitini

submission deadline 30 May 2025 | 1 articles | Viewed by 614 | Submission Open

Keywords: probiotic yeasts; molecular mechanisms; mycocins active; compounds; functional compounds

(This special issue belongs to the Section Molecular Microbiology)

Long Non-coding RNAs in Plants

edited by

Changning Liu

submission deadline 30 May 2025 | Viewed by 540 | Submission Open

Keywords: long noncoding RNAs; plants; gene regulation; development; stress responses

(This special issue belongs to the Section Molecular Plant Sciences)

Cotton Molecular Genomics and Genetics (Third Edition)

edited by

Jie Sun

submission deadline 30 May 2025 | 1 articles | Viewed by 509 | Submission Open

Keywords: cotton; biotic or abiotic stress; disease resistance; fiber yield and quality; gene editing; gene identification and function validation; genome-wide association study; QTL identification

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanisms in Mitochondria-Targeted Drug Delivery System

edited by

Maria Manuel Oliveira

and

Francisco Peixoto

submission deadline 30 May 2025 | Viewed by 482 | Submission Open

Keywords: mitochondria; mitochondrial diseases; nanoformulations; therapeutic agents; drug release; precision medicine

(This special issue belongs to the Section Molecular Pharmacology)

Advances in Molecular Biology on Mycobacteria: 2nd Edition

edited by

Rita Macedo

submission deadline 30 May 2025 | 1 articles | Viewed by 463 | Submission Open

Keywords: genus Mycobacterium; non-tuberculous mycobacteria; Mycobacterium tuberculosis; Mycobacterium leprae; molecular diagnosis; molecular surveillance methodologies; molecular resistance prediction

(This special issue belongs to the Section Molecular Microbiology)

Molecular Insights and Regulation Mechanisms of Tea Quality

edited by

Xujun Zhu

submission deadline 30 May 2025 | 1 articles | Viewed by 431 | Submission Open

Keywords: molecular ecology; spectroscopic techniques; tea quality; tea plant growth

(This special issue belongs to the Section Molecular Plant Sciences)

Gut Microbiota and Nutrition in Human Health (2nd Edition)

edited by

Sunmin Park

submission deadline 30 May 2025 | Viewed by 424 | Submission Open

Keywords: microbiome; gut; brain; obesity; diabetes; inflammation; liver; nutrition; probiotic; prebiotic

(This special issue belongs to the Section Molecular Microbiology)

Spectral Control of Stress Response in Plants

edited by

Gábor Kocsy

and Zsolt Gulyás

submission deadline 30 May 2025 | Viewed by 406 | Submission Open

Keywords: spectral control; stress response; light spectrum; photoreceptor; reactive oxygen; plant hormone; antioxidant; plant growth and development

(This special issue belongs to the Section Molecular Plant Sciences)

Drug Delivery Systems in Veterinary Medicine: Innovations and Applications

edited by

Hualin Fu

submission deadline 30 May 2025 | Viewed by 297 | Submission Open

Keywords: design of novel veterinary drug delivery systems; methods of preparing a veterinary drug delivery system; mechanisms of action of veterinary drug delivery systems; impact of veterinary drug delivery systems on in vivo processes of veterinary drugs; clinical evaluation of veterinary drug delivery systems

(This special issue belongs to the Section Molecular Pharmacology)

Latest Advances in Plant Abiotic Stress

edited by

Kincső Decsi

submission deadline 30 May 2025 | 1 articles | Viewed by 296 | Submission Open

Keywords: abiotic stress factors; priming effects; defense responses; biochemical pathway analyses; transcriptomics; plant conditioners; next-generation sequencing; genome-wide analyses

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular and Immunological Biomarkers in Cervical Cancer

edited by Janaina Cristiana de Oliveira Crispim and

Ricardo Ney Oliveira Cobucci

submission deadline 30 May 2025 | Viewed by 292 | Submission Open

Keywords: cervical cancer; molecular biomarkers; immunological biomarkers; human papillomavirus (HPV); tumor microenvironment; immune responses; immunotherapy; diagnostic biomarkers; prognostic biomarkers; therapeutic targets

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

New Insights into the Molecular Mechanisms of the UPR and Cell Stress

edited by

Quang Duy Trinh

submission deadline 30 May 2025 | Viewed by 272 | Submission Open

Keywords: unfolded protein response; ER stress; oxidative stress; mitochondrial dysfunction; cell stress; stress response; UPR signaling pathway; immunity; inflammation; infection

(This special issue belongs to the Section Molecular Biology)

Adipose Tissue and Adipose Tissue-Derived Stem Cells in Multidisciplinary Research

edited by Oliver Felthaus

submission deadline 30 May 2025 | Viewed by 260 | Submission Open

Keywords: adipose tissue; adipose-derived stem cells; regenerative medicine; tissue engineering

(This special issue belongs to the Section Molecular Biology)

New Perspectives in 3D Bioprinting

edited by Pamela Mozetic and

Alessio Bucciarelli

submission deadline 30 May 2025 | Viewed by 227 | Submission Open

Keywords: 3D bioprinting; regenerative medicine; pluripotent stem cells; disease modeling; precision medicine

(This special issue belongs to the Section Materials Science)

Thrombo-Inflammatory Signaling and Complications in Autoimmune Disorders

edited by

Alexandros Tsoupras

submission deadline 30 May 2025 | Viewed by 213 | Submission Open

Keywords: inflammation; thrombosis; platelets; coagulation; autoimmune disorders; rheumatoid arthritis; systematic erythematosus lupus; antiphospholipid syndrome; thrombo-inflammation; antithrombotic; antiplatelet

(This special issue belongs to the Section Molecular Immunology)

Sjogren's Disease: Multidimensional Perspectives on Pathogenesis, Clinical Manifestations, and Therapeutic Advancements

edited by

Xiang Lin

submission deadline 30 May 2025 | Viewed by 212 | Submission Open

Keywords: Sjö gren's disease; diagnosis; therapeutics; bioinformatics; pre-clinical; cytokine; lymphocytes; autoantibodies; exocrine glands

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Displaying special issue 351-400 on page 8 of 67.

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