Precision Medicine Approaches to Antifibrotic Therapy
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 31 May 2025 | Viewed by 536
Special Issue Editor
Interests: DNA repair; nanobiotechnology; inflammation; immunology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Recent advances in our understanding of fibrotic diseases have highlighted the need for personalized treatment strategies in antifibrotic therapy. This call for papers seeks contributions exploring precision medicine approaches in the development and application of antifibrotic treatments across various organ systems, including but not limited to the lungs, kidneys, liver, and skin. Key areas of interest include biomarker discovery and validation for disease susceptibility, early diagnosis, prognosis, disease progression, and treatment response prediction. We encourage submissions on the molecular endotyping of fibrotic diseases to guide targeted therapies, in addition to pharmacogenomic approaches to optimize antifibrotic drug selection and dosing. The application of machine learning in diagnosis, prognosis, and treatment decision-making is another crucial area for exploration. We also welcome research on the development of novel antifibrotic compounds tailored to specific disease endotypes. Additionally, we seek papers on the integration of multi-omics data (genomics, proteomics, and metabolomics) to enhance personalized treatment strategies and precision medicine approaches in clinical trial design for antifibrotic therapies. The role of environmental and lifestyle factors in personalizing antifibrotic treatments is another important area of investigation. Lastly, we are interested in studies comparing the effectiveness of precision medicine approaches versus standard care in antifibrotic therapy. We welcome original research articles, systematic reviews, meta-analyses, and perspective pieces that address these topics and contribute to advancing the field of precision medicine in antifibrotic therapy. The goal is to move beyond the current "one-size-fits-all" approach and develop more effective, tailored treatments that can improve outcomes for patients with fibrotic diseases.
Please note that this Special Issue is focused on molecular research; therefore, pure clinical research will not be accepted. However, clinical submissions including biomolecular experiments are welcome for consideration.
Dr. Karim Daliri
Guest Editor
Manuscript Submission Information
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Keywords
- fibrotic diseases
- antifibrotic therapy
- antifibrotic drug
- multi-omics data
- precision medicine
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