Molecular Characterization of Glioblastoma: Implications for Diagnosis and Personalized Treatment
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 31 October 2025 | Viewed by 88
Special Issue Editor
Special Issue Information
Dear Colleagues,
Glioblastoma remains the most aggressive and lethal primary brain tumor in adults, with limited therapeutic options and poor survival rates. Recent advances in molecular profiling technologies have transformed our understanding of glioblastoma biology, leading to refined diagnostic criteria, identification of distinct molecular subtypes, and emergence of personalized treatment strategies.
This Special Issue of the International Journal of Molecular Sciences brings together a collection of submissions that highlight recent developments in the molecular characterization of glioblastoma, with a focus on its diagnostic, prognostic, and therapeutic implications. The topics covered include the integration of DNA methylation-based classifiers into diagnostic workflows, the role of comprehensive genomic profiling in detecting actionable mutations and gene fusions, and the utility of transcriptomic and proteomic signatures in subclassifying tumors. The collection also addresses challenges in clinical implementation, including tumor heterogeneity, evolving classification systems, and the need for CLIA-certified platforms. Collectively, these articles underscore the critical role of precision oncology in glioblastoma management and point toward a future where individualized therapy guided by molecular diagnostics may significantly improve patient outcomes.
Dr. Madan Mohan Kwatra
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- glioblastoma
- diagnosis
- molecular characterization
- personalized treatment
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
