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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Bioactive Natural Compounds: Protecting Plants and Promoting Human Health, 2nd Edition submission deadline 20 Sep 2025 | 2 articles | Viewed by 2665 | Submission Open
Keywords: natural products; molecular biology; chemical characterization; bioactivity; mechanism of action; plant protection; human health promotion; antioxidant; anti-inflammation; biopesticides; biostimulants; nutraceuticals
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Drug Discovery and Development Focusing on Natural Products submission deadline 20 Sep 2025 | 1 articles | Viewed by 2611 | Submission Open
Keywords: natural products; drug R& D; herbal medicine; gut microbiota; mechanism of action; therapeutic targets
(This special issue belongs to the Section Molecular Pharmacology)
Chronic Liver Disease: From Pathophysiology to Treatment
edited by
submission deadline 20 Sep 2025 | 3 articles | Viewed by 2605 | Submission Open
Keywords: nonalcoholic fatty liver disease (NAFLD); metabolic dysfunction-associated steatotic liver disease (MASLD); metabolic dysfunction-associated steatohepatitis (MASH); type 2 diabetes (T2D)
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Computational Methods for Studying the Effects of Radiation on Human Beings submission deadline 20 Sep 2025 | 2 articles | Viewed by 2576 | Submission Open
Keywords: DNA damage; biophysical models; DNA geometrical models; computational radiobiology; Monte Carlo simulations; ionizing radiation; heavy ions; DNA damage repair
(This special issue belongs to the Section Molecular Biophysics)
Adapter CAR T Cells: From the Idea to the Clinic submission deadline 20 Sep 2025 | 1 articles | Viewed by 2527 | Submission Open
Keywords: CAR T cell therapy; chimeric antigen receptor; bispecific antibody; target module; autoimmune diseases; solid tumors
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Quadruplex DNA and Its Ligands for Disease Treatment
edited by
submission deadline 20 Sep 2025 | 3 articles | Viewed by 2518 | Submission Open
Keywords: quadruplex; i-motif; transcriptional regulation; apoptosis; cancer
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Compounds with Added Value from Marine Algae for Biomedical Applications submission deadline 20 Sep 2025 | 1 articles | Viewed by 2452 | Submission Open
Keywords: algae bioactive compounds; algal biotechnology for biomedical purposes; algal-derived biomedical materials; algal-based drug delivery systems; alginate; carrageenan; fucoidan; marine polysaccharides; marine peptides; marine polyphenols; marine antioxidants; marine bioactive compounds; marine glycosaminoglycans; marine biopolymers and biomaterials; marine lipids; marine-derived pharmaceuticals; marine-derived cosmeceuticals; marine-derived nutraceuticals; marine algae added-value products; marine drugs discovery; marine natural products; marine-derived anti-inflammatory agents; marine antimicrobial compounds; marine-derived anticancer agents; marine neuroprotective compounds; marine-derived anti-aging compounds; marine-based regenerative medicine; phycobiliproteins; seaweed-based tissue engineering materials; seaweed-derived bioactive molecules; seaweed extracts; seaweed-based wound healing materials
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular Mechanisms of Oxidative Stress in Kidney Disease
edited by Stefanos Roumeliotis
submission deadline 20 Sep 2025 | 2 articles | Viewed by 2444 | Submission Open
Keywords: chronic kidney disease; end-stage kidney disease; hemodialysis; peritoneal dialysis; oxidative stress; pro-oxidants; inflammation; atherosclerosis; cardiovascular disease
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Cytokine Networks in Inflammatory Skin Diseases
edited by
submission deadline 20 Sep 2025 | 2 articles | Viewed by 2444 | Submission Open
Keywords: chronic inflammatory skin diseases; immunopathogenesis; inflammatory pathways; cytokines; molecular targets; psoriasis; atopic dermatitis; hidradenitis suppurativa; urticaria; lichen planus
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Strategies to Overcome Antibiotic Resistance in Carbapenem-Producing Bacteria submission deadline 20 Sep 2025 | 1 articles | Viewed by 2408 | Submission Open
Keywords: antibiotic resistance; antimicrobial agents; bacterial pathogens; carbapenemases; genomics; molecular mechanisms; therapeutic targets
(This special issue belongs to the Section Molecular Biology)
Molecular Advances in Mental Health and Disorders
edited by Eva Christina Schulte
submission deadline 20 Sep 2025 | 1 articles | Viewed by 2402 | Submission Open
Keywords: molecular studies; mental health disorders; model systems; molecular epidemiology; omics   TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian   //   TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //     This page is in English   Translate to Simplified Chinese         Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh   Always translate English to Simplified ChinesePRO Never translate English Never translate admin.mdpi.com
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Utilizing Induced Pluripotent Stem Cells and Cardiomyocytes: From Basic Research to Disease Modeling
edited by
submission deadline 20 Sep 2025 | 1 articles | Viewed by 2392 | Submission Open
Keywords: induced pluripotent stem cells; cardiomyocytes; disease modeling; basic research; translational applications
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Genetic, Epigenetic and Microbiota Molecular Insights for Crop Resilience to Abiotic Stress
edited by
submission deadline 20 Sep 2025 | 2 articles | Viewed by 2366 | Submission Open
Keywords: abiotic stress; tolerance; crop resilience; crop sustainability; environmental conditions; climate change; gene regulation; epigenetic mechanisms; microbiota communities; microbiome
(This special issue belongs to the Section Molecular Plant Sciences)
Microbiota’s Role in Respiratory Disorders and Diseases
edited by and Mauro Carone
submission deadline 20 Sep 2025 | 1 articles | Viewed by 2292 | Submission Open
Keywords: microbiota; microbiome; metabolome; transcriptome; microbiota gut/lung axis; microbiota gut/oral axis; respiratory disorders; respiratory diseases; respiratory rehabilitation
(This special issue belongs to the Section Molecular Microbiology)
Molecular Targets and Immunotherapy for Autoimmune Diseases
edited by
submission deadline 20 Sep 2025 | 1 articles | Viewed by 2282 | Submission Open
Keywords: autoimmunity; autoimmune diseases; immunotherapy; signaling pathway; molecular targets; antibody; T cells; B cells
(This special issue belongs to the Section Molecular Immunology)
Molecular Advances in Parvovirus
edited by Zahra Kadri
submission deadline 20 Sep 2025 | 1 articles | Viewed by 2271 | Submission Open
Keywords: parvovirus structure; parvovirus replication; parvovirus proteome; cell signaling pathways; transcription; translation and post-translational modification; host restriction factor; host/parvovirus interaction; recombinant virus and VLP; immune evasion and/or activation; host tropism (cell type and species); new experimental models and approaches
(This special issue belongs to the Section Molecular Microbiology)
The Roles of Mesenchymal Stem/Stromal Cells in Tumor Therapies
edited by Francesco Agostini
submission deadline 20 Sep 2025 | 1 articles | Viewed by 2250 | Submission Open
Keywords: mesenchymal stem cells; tumor; cancer patients; ex vivo cell modification; cell and gene therapy; targeted drug delivery; homing; migration; current regulatory guidelines; MSC therapeutic potential
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Emerging Heterocycles submission deadline 20 Sep 2025 | 1 articles | Viewed by 2186 | Submission Open
Keywords: synthesis; reactions; applications; biological activity; medicinal chemistry; natural products; alkaloids; new methodology
(This special issue belongs to the Section Biochemistry)
Rheumatoid Arthritis: Molecular Mechanisms and Immunotherapy
edited by Irena Manolova
submission deadline 20 Sep 2025 | 1 articles | Viewed by 2178 | Submission Open
Keywords: rheumatoid arthritis; pathogenesis; innate immunity; adaptive immunity; inflammation; cytokines; autoantibodies; immunotherapy; clinical outcome
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Insights on Drug Discovery, Design, and Treatment
edited by Chih Kang Chiang
submission deadline 20 Sep 2025 | 2 articles | Viewed by 2169 | Submission Open
Keywords: antibacterial drugs; antiviral drugs; antioxidant drugs; anti-inflammatory drugs; antibiotics; anticancer drugs; drug discovery; drug development; drug design; drug delivery; drug carriers; nanoparticles; molecular modeling; molecular mechanisms; crystallography; pharmacokinetics; molecular activity; inhibitors and antagonists
(This special issue belongs to the Section Molecular Pharmacology)
Heart Failure Risk Factors and Therapies-Molecular Basis
edited by
submission deadline 20 Sep 2025 | 2 articles | Viewed by 2124 | Submission Open
Keywords: heart failure; risk factors; inflammatory; neutrophils; cytokines; pharmacological; therapies; molecular-based processes
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Antiphospholipid Syndrome: From Pathophysiology to Therapy
edited by
submission deadline 20 Sep 2025 | 1 articles | Viewed by 2111 | Submission Open
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Editorial Board Members’ Collection Series: Cancer Metabolism submission deadline 20 Sep 2025 | 1 articles | Viewed by 2110 | Submission Open
Keywords: cancer metabolism; metabolic pathway; glucose consumption and energy production; amino acid requirement
(This special issue belongs to the Section Molecular Oncology)
Musculoskeletal Diseases: Inflammation, Degeneration or Mechanical Stress
edited by
submission deadline 20 Sep 2025 | 2 articles | Viewed by 2098 | Submission Open
Keywords: musculoskeletal diseases; inflammation; degeneration; mechanical stress; aging
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Oxidative Stress and Cell Damage
edited by Haruhiko Inufusa, Koji Abe and Shigeru Hirano
submission deadline 20 Sep 2025 | 1 articles | Viewed by 2080 | Submission Open
Keywords: oxidative stress; damages on cells; organs; body; prevention damages; parameter of oxidative stress; antioxidants
(This special issue belongs to the Section Molecular Biology)
Nutraceuticals for the Maintenance of Brain Health submission deadline 20 Sep 2025 | 1 articles | Viewed by 2077 | Submission Open
Keywords: vitamin; nutraceutics; brain; neuroinflammation; neurodegeneration; cognitive function
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Application of Artificial Intelligence in Molecular Sciences
edited by
submission deadline 20 Sep 2025 | 2 articles | Viewed by 2074 | Submission Open
Keywords: artificial intelligence; deep learning; algorithms; molecular modeling and simulation; materials discovery; analysis of biological sequence data; computational chemistry; bioinformatics; genomics; protein structure prediction; molecular dynamics simulation
(This special issue belongs to the Section Molecular Informatics)
Application of Genetic Engineering in Treatments for Human Diseases
edited by Claudio Mussolino
submission deadline 20 Sep 2025 | 2 articles | Viewed by 2074 | Submission Open
Keywords: genome editing; epigenome editing; CRISPR-Cas systems; gene therapy; precision medicine; molecular mechanisms; innovative therapies; gene expression regulation
(This special issue belongs to the Section Molecular Genetics and Genomics)
Integrated Approaches, Molecular Mechanism and Therapies in Ocular Surface Diseases
edited by , and
submission deadline 20 Sep 2025 | 2 articles | Viewed by 2046 | Submission Open
Keywords: ocular surface diseases; dry eye; corneal ulcers; persistent epithelial defects; blood-derived products; blood-based therapies
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Gut-Brain Axis: Genomic and Metagenomic Involvement
edited by and Elias Odusseas Tzavellas
submission deadline 20 Sep 2025 | 1 articles | Viewed by 2028 | Submission Open
Keywords: gut– brain axis; central nervous system; gastrointestinal tract; genomic; metagenomic
(This special issue belongs to the Section Molecular Neurobiology)
Current Trends in MOF (Metal–Organic Framework) and Metal X-ides Development, 2nd Edition
edited by Siwei Li
submission deadline 20 Sep 2025 | 2 articles | Viewed by 2020 | Submission Open
Keywords: MOF; metal carbide; metal sulfide; metal phosphide; catalysis; biomedicine; electromagnetic absorption; energy conversion and storage
(This special issue belongs to the Section Materials Science)
Molecular Genetics, Breeding, and Multi-Omics Approaches in Rice Research
edited by
submission deadline 20 Sep 2025 | 2 articles | Viewed by 2006 | Submission Open
Keywords: rice genetics and breeding; molecular breeding of rice; rice genomics and proteomics; genes related to abiotic stress tolerance in rice; molecular biology and multi-omics in rice research
(This special issue belongs to the Section Molecular Plant Sciences)
Nanofibrous Biomaterials for Biomedicine and Medical Applications
edited by Jong-Young Kwak
submission deadline 20 Sep 2025 | 1 articles | Viewed by 2000 | Submission Open
Keywords: nanofibers; biomaterials; 3D scaffold; 3D cell culture; tissue engineering; drug release
(This special issue belongs to the Section Materials Science)
Research of Hydroxyapatite-Based Materials and Their Applications
edited by
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1989 | Submission Open
Keywords: hydroxyapatite; nanobiocomposite; biomedical applications; coatings; environment remediation; biological properties; drug delivery; pollutant adsorption efficiency; morphology and structural features
(This special issue belongs to the Section Materials Science)
Molecular Dimensional Design, Synthesis Modification and Application of Sustainable Polymer Materials
edited by
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1982 | Submission Open
Keywords: sustainable polymeric materials; 3D printing; sustainability; environmental impact; molecular modifications
(This special issue belongs to the Section Materials Science)
False-Positive and False-Negative Laboratory Biomarkers
edited by Michela Salvatici and Lorenzo Drago
submission deadline 20 Sep 2025 | 2 articles | Viewed by 1936 | Submission Open
Keywords: biomarkers; false positives/negatives; protein biomarkers; nucleic acid markers; multi-omics; single-cell sequencing; liquid biopsy
(This special issue belongs to the Section Biochemistry)
Stem Cells and Regenerative Medicine: In Vitro and In Vivo Studies—2nd Edition
edited by
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1921 | Submission Open
Keywords: stem cells; stem cell homing; stem cell tracking; regeneration; tissue injury; immunomodulation; biomaterials; tissue-on-a-chip; organoids; differentiation
(This special issue belongs to the Section Molecular Biology)
Probiotics, Prebiotics and Postbiotics: The Secrets of Promoting Microbial Balance in the Gut
edited by
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1909 | Submission Open
Keywords: probiotics; prebiotics; postbiotics; gut microbiota; gut epithelial integrity
(This special issue belongs to the Section Molecular Microbiology)
Tumor Microenvironment and Cancer Progression: Molecular Insights for Targeted Therapy
edited by
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1897 | Submission Open
Keywords: tumor microenvironment; immune response modulation; signaling pathways; extracellular matrix components; tumor evolution
(This special issue belongs to the Section Molecular Oncology)
Molecular Advances in Olive and Its Derivatives
edited by
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1881 | Submission Open
Keywords: olive; structural and functional genomics; genomic variation; breeding; biotechnologies; next-generation sequencing
(This special issue belongs to the Section Molecular Plant Sciences)
Novel Technologies in the Study of the Pathogenesis of Cardiac Diseases submission deadline 20 Sep 2025 | 1 articles | Viewed by 1876 | Submission Open
Keywords: artificial Intelligence; multi-omics; organoids; engineered heart tissue; advanced imaging; personalized medicine
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Recent Developments in Metabolism of Algal Toxins in Animals submission deadline 20 Sep 2025 | 1 articles | Viewed by 1870 | Submission Open
Keywords: marine toxins; bioacumulation; chemical conversion; detoxification mechanisms; toxin gene clusters
(This special issue belongs to the Section Molecular Toxicology)
Fungal Pathogen-Host Interactions
edited by Patricia Albuquerque
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1869 | Submission Open
Keywords: medical mycology; host– microbe interactions; macrophages; dendritic cells; neutrophils
(This special issue belongs to the Section Molecular Microbiology)
Cellular Oxygen Homeostasis—3rd Edition
edited by
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1849 | Submission Open
Keywords: cellular oxygen homeostasis; redox signaling; cellular oxygen sensing; hypoxia; hyperoxia
(This special issue belongs to the Section Molecular Biology)
Anti-Inflammatory and Metabolic Effects of G Protein-Coupled Receptor Signaling
edited by
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1805 | Submission Open
Keywords: G protein-coupled receptors (GPCRs); seven transmembrane domain (7TM) receptors; metabotropic receptors; membrane receptors; GPCRs signaling; GPCRs signaling pathways; anti-inflammatory effects; inflammatory diseases; metabolic diseases; metabolic effects; anti-inflammatory treatment
(This special issue belongs to the Section Molecular Immunology)
Molecular Insights into Role of Anthranilic Acid in Neuropsychiatric Diseases submission deadline 20 Sep 2025 | 1 articles | Viewed by 1777 | Submission Open
Keywords: anthranilic acid; Alzheimer’ s disease; autism; schizophrenia; bipolar disorder; major depressive disorder; post-partum depression; COVID-19; interferons; attention deficit disorder; cognitive impairment; G-protein-coupled receptor 109A; microbiome; gut– brain axis
(This special issue belongs to the Section Molecular Neurobiology)
The Role of SARS-CoV-2 in Immunomodulation—Post-Pandemic Reflection on the Role of Viruses in Human Immunology submission deadline 20 Sep 2025 | 2 articles | Viewed by 1756 | Submission Open
Keywords: SARS-CoV-2; COVID-19; immunomodulation; T cells; B cells; dendritic cells; monocytes; cytokines
(This special issue belongs to the Section Molecular Immunology)
C. elegans as a Disease Model: Molecular Perspectives: 2nd Edition submission deadline 20 Sep 2025 | 2 articles | Viewed by 1730 | Submission Open
Keywords: Caenorhabditis elegans; model organism; disease model; neurodegenerative diseases; cancer model; ageing
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Mechanisms and Treatment of Chronic Kidney Disease
edited by Xinming Chen
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1727 | Submission Open
Keywords: diabetes; cardiovascular diseases; nephrology; diabetic nephropathy
(This special issue belongs to the Section Molecular Biology)
New Cardiovascular Risk Factors: 2nd Edition
edited by
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1723 | Submission Open
Keywords: atherosclerosis; cardiovascular risk; arterial stiffness; blood pressure; vitamin D; miRNA; inflammation
(This special issue belongs to the Section Molecular Biology)
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