Microbiota’s Role in Respiratory Disorders and Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Microbiology".
Deadline for manuscript submissions: 20 September 2025 | Viewed by 2265
Special Issue Editors
Interests: toxicology; xenobiotics; anethesia and critical care; human microbiota
Special Issues, Collections and Topics in MDPI journals
Interests: rehabilitation aspects of chronic respiratory diseases; sleep breathing disorders; physical exercise in respiratory pathology; Health and Quality of Life (QoL) status of patients with chronic respiratory failure on long-term oxygen therapy (LTOT) or in home ventilatory care; measures of outcome indicators of therapeutic processes
Special Issue Information
Dear Colleagues,
Some unfavorable changes (dysbiosis) that occur in the human microbiota can modify its resident composition, with both local and systemic negative consequences. Therefore, this qualitative and quantitative variation can also modify the metabolome by further alternating the homeostasis of the organism, which can facilitate the birth or worsening of certain diseases or disorders in all systems, including the respiratory one, thanks to the various axes of communication with the intestine (gut, lung, etc.). Intestinal dysbiosis can be of various types depending on the cause, as it can be induced by internal factors, for example, local alterations of the intestinal microenvironment, and by external factors such as diet, lifestyle, potentially toxic substances (such as smoking, alcohol abuse, cannabinoids, methamphetamines, cocaine, pesticides, heavy metals, etc.), and more. Therefore, it has been noted that the gut microbiota plays an important role in the development of immunity and in the correct functioning of the respiratory tract. Considering this, it is also important to look for interactions between the microbiota’s gut/upper and lower airway axes. So far, the biomechanisms underlying these interactions are becoming a key springboard for medical research in treatment and prevention. Thus, studying in more depth the interactions that the human microbiota of the host has with the emergence or facilitation of these respiratory pathological conditions with these factors plays a crucial role in the prevention and management (such as respiratory rehabilitation) of them.
Sub-topics of this Special Issue (relative to the microbiota and/or metabolome):
- Obstructive sleep apnea syndrome (OSAS);
- Asthma;
- Respiratory allergies;
- Autoimmune lung diseases;
- Chronic obstructive pulmonary disease (COPD);
- Pulmonary infections (by virus, bacteria, fungi, and parasitosis);
- Intoxications by xenobiotics and drugs;
- Gender medicine;
- Pulmonary rehabilitation.
We are soliciting articles on the dysbiosis consequences and the modulation of microbiota regarding the management of respiratory diseases and disorders also related to the connection with another microbiota’s axis. We are particularly interested in recent articles reporting on the relevance of biomolecular regulation mechanisms through various factors of host–microbiota interactions by inviting researchers to contribute original research papers and review articles that will help us understand these underlying molecular mechanisms for the development of potential discoveries and strategies for curing diseases from dysbiosis and the connections with the gut/lung axis and the other microbiota’s axis.
We sincerely hope that you, or a senior member of your laboratory, will be able to contribute to this Special Issue.
Dr. Ioannis Alexandros Charitos
Dr. Mauro Carone
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- microbiota
- microbiome
- metabolome
- transcriptome
- microbiota gut/lung axis
- microbiota gut/oral axis
- respiratory disorders
- respiratory diseases
- respiratory rehabilitation
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue policies can be found here.
