Musculoskeletal Diseases: Inflammation, Degeneration or Mechanical Stress

Dear Colleagues,

Musculoskeletal disorders are conditions that may result from hereditary, congenital, or acquired pathological states. Their features may vary in nature, but all of them affect bones, joints, connective tissues, and muscles.

With aging, these tissues gradually are subjected to degeneration due to biological and mechanical stress. Other factors that may influence the development of these pathologies are inflammation, infections, mechanical traumas, and toxic metabolic diseases. Musculoskeletal disorders also are the most costly and disabling conditions in developing countries. Loss of function and chronic pain are the primary mechanisms that lead to disability and work loss. This Special Issue aims to invite reviews and original articles that focus on musculoskeletal disorders, both hereditary and acquired. The collection places a particular emphasis on the molecular pathways affecting joints and connective tissues, as well as the properties and composition of the extracellular matrix.

Dr. Gianluigi Pasta
Guest Editor

Manuscript Submission Information

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