The Gut-Brain Axis: Genomic and Metagenomic Involvement
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 20 September 2025 | Viewed by 2079
Special Issue Editors
Interests: genetics; molecular biology; proteomics; microbiome; cancer; inflammation; nanomedicine
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The gut–brain axis is the two-way biochemical signaling that occurs among the gastrointestinal tract (GI tract) and the central nervous system (CNS). Several data from functional pathway analyses suggest that genetic factors may influence a wide range of biological pathways including the gut-brain axis and different mechanisms in the etiopathology of IBS, and neuropsychiatric disorders, indicating as genetic architecture between GI and CNS diseases. We should also notice that the microbiota-gut-brain axis represents also a sophisticated communication network between the brain and the gut and evidence shows that alterations in gut microbiota composition, significantly impact GI (ie IBS, Crohn’s disease, Ulcerative colitis, GI-cancers, etc), and CNS disorders (ie anxiety, depression, schizophrenia, autism, alcoholism, Parkinson's disease, Alzheimer's disease, etc). Thus, more in-depth studies are necessary to fully understand and harness the therapeutic potential of the genomic and metagenomic implication on the gut-brain axis signaling in health and disease.
Prof. Dr. Maria Gazouli
Dr. Elias Odusseas Tzavellas
Guest Editors
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Keywords
- gut–brain axis
- central nervous system
- gastrointestinal tract
- genomic
- metagenomic
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