Molecular, Genetic, and Omics Approaches to Disorders in Bone–Inflammation Crosstalk
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 17
Special Issue Editor
2. Department of Genetics, Biosciences Center, Federal University of Pernambuco, Recife Campus, Recife 50730-120, Brazil
Interests: immunity; lupus; arthritis; rheumatology; osteoporosis
Special Issue Information
Dear Colleagues,
This Special Issue will highlight recent advances in the molecular mechanisms underlying the interplay between bone physiology and inflammatory processes. The bidirectional relationship between skeletal homeostasis and immune regulation plays a pivotal role in various chronic diseases, including autoimmune disorders, osteoimmunological conditions, and systemic inflammatory syndromes. We invite contributions exploring the genetic and epigenetic regulation, molecular signaling pathways, and cellular interactions involved in bone–inflammation crosstalk. Studies employing high-throughput omics technologies such as genomics, transcriptomics, proteomics, metabolomics, and single-cell approaches are particularly welcome. This Special Issue will provide a platform for novel insights into the identification of biomarkers, therapeutic targets, and personalized strategies for managing complex disorders, including rheumatoid arthritis, osteoporosis, psoriatic arthritis, and lupus-related bone disease. Additionally, we welcome translational studies that combine basic science and clinical data to develop precision medicine approaches to addressing osteoimmune disorders. By assembling multidisciplinary perspectives, this Special Issue will advance our understanding and promote innovation in the diagnosis, treatment, and prevention of bone and inflammatory diseases.
Prof. Dr. Paula Sandrin-Garcia
Guest Editor
Manuscript Submission Information
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Keywords
- bone physiology
- inflammatory
- epigenetic regulation
- molecular signaling pathways
- cellular interactions
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