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Mechanistic Studies on Microbiota–Host Interactions

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Microbiology".

Deadline for manuscript submissions: 30 September 2026 | Viewed by 1

Special Issue Editor


E-Mail Website
Guest Editor
Department of Forest Products and Biotechnology, Kookmin University, Seoul 02707, Republic of Korea
Interests: microbiome; gut-organ axis; host-microbe interactions; multi-omics; metagenomics; metabolomics; transcriptomics

Special Issue Information

Dear Colleagues,

The microbiota fundamentally shapes host physiology through molecular mechanisms that regulate immunity, metabolism, and systemic inflammation. This Special Issue, “Mechanistic Studies on Microbiota–Host Interactions,” seeks studies aimed at elucidating the causal relationships between microbiota-derived factors and host signaling pathways.

In particular, we welcome studies that focus on the host perspective, specifically those that elucidate how host genetic factors or proteins regulate microbial signaling or the intestinal environment. Additionally, we welcome research on microbial metabolites or extracellular vesicles in gut–organ axes (e.g., the gut–liver and gut–brain axes). Given that the International Journal of Molecular Sciences (IJMS) focuses on insights at the molecular level, we will prioritize submissions that integrate clinical studies or in vivo/in vitro models with rigorous biochemical analyses. Key research themes include host-driven microbial regulation, immune signaling, and metabolic reprogramming.

We sincerely look forward to your innovative submissions and contributions.

Dr. Min-Jin Kwak
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • microbiome
  • host-microbe interactions
  • gut-organ axis
  • extracellular vesicles
  • multi-omics
  • metagenomics
  • metabolomics
  • transcriptomics
  • barrier function

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Published Papers

This special issue is now open for submission.
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