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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Roles of Phytochemicals in Cancer Prevention and Therapeutics: 2nd Edition

edited by

Daniel Gabriel Pons

submission deadline 20 Aug 2025 | Viewed by 384 | Submission Open

Keywords: phytochemicals; cancer prevention; cancer therapeutics; oxidative stress; inflammation; energetic metabolism

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Interfaces for the Impact of Magnetic Pulses or EMF in Molecular Biology

edited by Richard H. W. Funk

submission deadline 20 Aug 2025 | Viewed by 384 | Submission Open

Keywords: electromagnetic treatment; magnetic pulses; biological interface; cell biology; molecular biology; signaling cascades; clinical treatment; monitoring; sensors

(This special issue belongs to the Section Molecular Biophysics)

The Role of Cannabinoids in Human Health and Disorder

edited by

Grazia Chiellini

and Beatrice Polini

submission deadline 20 Aug 2025 | Viewed by 366 | Submission Open

Keywords: cannabinoids; cannabinoid receptors; endocannabinoid system; ECS synthetic modulators; clinical trials

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advancements and Applications of Phyto-Nanotherapy in Targeted Disease Treatment

edited by

Adewale Fadaka

and

Nicole Remaliah Samantha Sibuyi

submission deadline 20 Aug 2025 | Viewed by 355 | Submission Open

Keywords: phyto-nanotherapy; medicinal plants; nanoparticles; targeted drug delivery; phytochemicals; phytotherapy; green nanotechnology; chronic diseases; infectious diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Exploring the Role of Antioxidants in Supplements and Drug Responses

edited by

Maria Greabu

submission deadline 20 Aug 2025 | Viewed by 354 | Submission Open

Keywords: NSAIDs; glucocorticoids; vitamin E; antioxidants; oxidative stress; inflammation

(This special issue belongs to the Section Molecular Immunology)

Insights into Neurological and Psychiatric Diseases from Invertebrate Models

edited by

Efthimios M. C. Skoulakis

submission deadline 20 Aug 2025 | Viewed by 352 | Submission Open

Keywords: disease model development; disease model validation; GWAS validation; ameliorative approaches; pharmacogenetics; pharmacoproteomics; disease mechanisms; suppressor/enhancer genetic screens; synthetic lethality screens; biomarker screens and validation

(This special issue belongs to the Section Molecular Neurobiology)

Roles and Functions of Micronutrients in Gut Microbiota and Intestinal Inflammation

edited by

Chao Wang

submission deadline 20 Aug 2025 | Viewed by 348 | Submission Open

Keywords: micronutrients; gut microbiota; intestinal inflammation; intestinal barrier; oxidative stress

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Exploring Mitochondria in Neurodegenerative Disorders: Unveiling Mechanisms and Therapeutic Strategies

edited by

Saeid Ghavami

and Mohamad-Reza Aghanoori

submission deadline 20 Aug 2025 | Viewed by 348 | Submission Open

Keywords: neurodegenerative disorders; energy homeostasis and metabolism; mitochondrial dysfunction; mitochondrial dynamics; mitophagy and autophagy; synaptic function; axonal transport; oxidative stress; calcium homeostasis; treatments targeting mitochondria; mitochondrial biogenesis; neuroprotection; therapeutic strategies

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Biological Determination of Physical Injury

edited by

Sorin Hostiuc

submission deadline 20 Aug 2025 | Viewed by 346 | Submission Open

Keywords: molecular markers; physical injury; micro-RNA; dating of traumatic injuries

(This special issue belongs to the Section Molecular Biology)

Advances in Heparin, Heparan Sulfate and Heparanase, 2nd Edition

edited by

Nobuaki Higashi

submission deadline 20 Aug 2025 | Viewed by 329 | Submission Open

Keywords: allergy; angiogenesis; cancer metastasis; cellular trafficking; exosome; fibrosis; glycocalyx; glycosaminoglycans; heparan sulfate; heparanase; heparin; immune responses; inflammation; inbibitor development; sepsis/SIRS (systemic inflammatory response syndrome); sulfatase; viral infections

(This special issue belongs to the Section Macromolecules)

Analysis on Effector and Regulatory Molecules in Renal Diseases

edited by

Takashi Oda

submission deadline 20 Aug 2025 | 1 articles | Viewed by 316 | Submission Open

Keywords: effector molecules; regulatory molecules; membrane attack complex (MAC); perforin; granzyme; immune complex; neutrophil extracellular traps (NETs); proteolytic enzymes; reactive oxygen species; infection-related glomerulonephritis (IRGN); nephritis-associated plasmin receptor (NAPlr); streptococcal pyrogenic exotoxin B (SPEB); adhesion molecules

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Role of Melatonin in Plants: 3rd Edition

edited by

Małgorzata M. Posmyk

submission deadline 20 Aug 2025 | Viewed by 316 | Submission Open

Keywords: melatonin; phytomelatonin; plants; seed germination; seasonal and circadian rhythms; flowering; fruit ripening; plant immunity; abiotic stresses

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Insights into Fruit Crops Development

edited by

Xingguo Li

submission deadline 20 Aug 2025 | Viewed by 305 | Submission Open

Keywords: fruit crops; fruit tree; proteomics; genomics; metabolomics; biotic stress; abiotic stress

(This special issue belongs to the Section Molecular Plant Sciences)

Nanotechnology in Drug Delivery: Applications and Perspectives

edited by Ádám Juhász

submission deadline 20 Aug 2025 | Viewed by 302 | Submission Open

Keywords: nanostructured materials; drug delivery; drug– carrier interactions; hydrogel; aerogels; associated colloids; surfactants; macromolecules; blood– brain barrier; controlled release

(This special issue belongs to the Section Molecular Nanoscience)

Genetic Mechanisms of Neurological Disorders

edited by

Patrícia Maciel

and Sara Duarte-Silva

submission deadline 20 Aug 2025 | Viewed by 301 | Submission Open

Keywords: neurodevelopmental disorders; neurodegenerative disorders; neuropsychiatric disorders; genetics; molecular biology; cellular models; animal models; pathogenesis; biomarkers; therapeutic targets; drug discovery; therapy

(This special issue belongs to the Section Molecular Genetics and Genomics)

Inflammation and Metabolic Response in Mitochondrial Diseases

edited by

Guido Primiano

submission deadline 20 Aug 2025 | Viewed by 300 | Submission Open

Keywords: mitochondrial diseases; mitochondria; mtDNA; metabolic remodeling; inflammation; immunity; cell death; neurodegenration

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Artificial Intelligence in Human Disease: Current and Future Perspectives in Digital Medicine

edited by

Dumache Raluca-Oana

submission deadline 20 Aug 2025 | Viewed by 296 | Submission Open

Keywords: molecular genetics; artificial intelligence; pharmacogenomics; internet of things; molecular pathology; genomic medicine

(This special issue belongs to the Section Molecular Informatics)

New Insights in Nanomaterials and Electroactive Molecules—in Memory of Prof. Royce W. Murray

edited by

Zeev Porat

submission deadline 20 Aug 2025 | Viewed by 282 | Submission Open

Keywords: nanomaterials; organic electrochemistry; macromolecules and polymers; analytical chemistry

(This special issue belongs to the Section Molecular Nanoscience)

Signaling Pathways in Neuroinflammation or Neurodegenerative Disorders

edited by

Marika Cordaro

submission deadline 20 Aug 2025 | Viewed by 273 | Submission Open

Keywords: inflammation; neuroinflammation; oxidative stress; neurodegenerative disorders; pathology; molecular pathways; dysregulation; mitochondrial dysfunction

(This special issue belongs to the Section Molecular Neurobiology)

Tumor Specific Immunotherapeutic Targets

edited by

Roberto Perris

submission deadline 20 Aug 2025 | Viewed by 266 | Submission Open

Keywords: immunotherapy; immunotherapeutics; tumour-specific antigens; immunotherapeutic targets; multi-omics approaches

(This special issue belongs to the Section Molecular Immunology)

Molecular Mechanisms of Tumorigenesis of Human and Animal Stem Cells

edited by

Daniela Salvatori

submission deadline 20 Aug 2025 | Viewed by 248 | Submission Open

Keywords: malignancy; stem cells; safety; chromosal aberrations; animal; human; teratoma assay; in vitro assays

(This special issue belongs to the Section Molecular Oncology)

New Insights into Hyaluronan in Human Medicine

edited by

Monica Salamone

submission deadline 20 Aug 2025 | Viewed by 247 | Submission Open

Keywords: hyaluronan; regenerative medicine; inflammation; cancer therapy; metabolomics ; hyaluronidases; cell– matrix interaction; glucose metabolism; pathological processes

(This special issue belongs to the Section Biochemistry)

Advances in the Purinergic System

edited by Margarete Dulce Bagatini

submission deadline 20 Aug 2025 | Viewed by 241 | Submission Open

Keywords: purinergic system; receptors; ectonucleotidases; CD39; CD73; purinergic signaling

(This special issue belongs to the Section Biochemistry)

Research Progress of Nanodrug Delivery System

edited by Kenta Morita

submission deadline 20 Aug 2025 | Viewed by 227 | Submission Open

Keywords: drug delivery; nanomaterials; nanomedicine; pharmacokinetics; theranostics; imaging; controlled release

(This special issue belongs to the Section Molecular Nanoscience)

Obesity and Cancer Risk: Molecular Mechanisms and Perspectives

edited by

Hendrik Lehnert

submission deadline 20 Aug 2025 | Viewed by 226 | Submission Open

Keywords: epidemiology of obesity and cancer; experimental models of cancer in obesity; genetic and epigenetics of obesity and metabolic dysfunction associated cancer; tumor microenvironment; basis of metastatic spread of cancer in obesity; therapeutic modeling and targeting

(This special issue belongs to the Section Molecular Oncology)

Nrf1/2/3 and Other Antioxidant Transcription Factors in Health and Disease

edited by

Eleonora Stanca

submission deadline 20 Aug 2025 | Viewed by 110 | Submission Open

Keywords: transcription factor; oxidative stress; NRF1/2; NRF3; NFkB; P53; antioxidant-response elements; neurologial diseases; metabolic diseases; cancer

(This special issue belongs to the Section Molecular Biology)

Stem Cells Research: Advancing Science and Medicine

edited by Susana Rosa

submission deadline 20 Aug 2025 | Viewed by 94 | Submission Open

Keywords: stem cell; stem cell biology; stem cell-based therapies; regenerative medicine; disease modeling

(This special issue belongs to the Section Biochemistry)

Development and Applications of Biodegradable and Bioactive Materials

edited by

Mercedes Ana Peltzer

submission deadline 20 Aug 2025 | Viewed by 61 | Submission Open

Keywords: biopolymers; bioplastics; sustainability; food packaging; medicine and cosmetic; bioactive compounds; wound healing; active and intelligent packaging

(This special issue belongs to the Section Materials Science)

Molecular Studies of Endometriosis and Associated Diseases

edited by Sarah J Holdsworth-Carson

submission deadline 21 Aug 2025 | 4 articles | Viewed by 5796 | Submission Open

Keywords: adenomyosis; autoimmune diseases; cardiometabolic conditions; endometriosis; fatigue; heavy menstrual bleeding; irritable bowel syndrome; migraine; painful bladder syndrome; pelvic floor muscle dysfunction; pelvic inflammatory disease; pelvic pain; peritoneal adhesions; polycystic ovarian syndrome; pregnancy complications; ovarian cancer; uterine fibroids

(This special issue belongs to the Section Molecular Biology)

Advances in Metabolic Phenotypes of Pediatric Obesity

edited by Simona Georgiana Popa

submission deadline 22 Aug 2025 | 1 articles | Viewed by 831 | Submission Open

Keywords: cardiometabolic phenotypes of pediatric obesity; metabolomic profiles; microbiota; entero-insular axis; adipocytokines; precision therapy

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Endothelial Cells in Cancer: Molecular Advance

edited by Dae Joong Kim

submission deadline 22 Aug 2025 | Viewed by 148 | Submission Open

Keywords: tumor angiogenesis; metastasis; VEGFs; FGFs; Ang2; immune surveillance; antigen presentation; EC adhesion molecules; LYVE-1; lymphatic vessel; antigen-presenting cell; lymphocytes; high endothelial venule

(This special issue belongs to the Section Biochemistry)

New Insights into Bioactive Peptides: Design, Synthesis, Structure-Activity Relationship (2nd Edition)

edited by

Marilisa Leone

and

Flavia Anna Mercurio

submission deadline 25 Aug 2025 | 8 articles | Viewed by 9615 | Submission Open

Keywords: peptides; protein-peptide interactions; PPI inhibition and modulation; peptide drugs; peptidomimetics; cyclic peptides; stapled peptides; diagnostic peptides; peptides for drug delivery; multidisciplinary approaches TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian // TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back // This page is in English Translate to Simplified Chinese Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Biological Research on Plant Bioactive Compounds

edited by

Adriana Trifan

and

Simon Vlad Luca

submission deadline 25 Aug 2025 | 8 articles | Viewed by 8484 | Submission Open

Keywords: plant bioactive compounds; extraction and analysis of plant bioactive compounds; bioactivity and pharmacokinetics of plant compounds; natural products and modern diseases; plant bioactive compounds and by-products; discovery and development of natural plant drugs

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Isolation and Biological Activities of Natural Products: Focus on Molecular Advance

edited by Pedro Ferreira and

Patricia Reboredo-Rodríguez

submission deadline 25 Aug 2025 | 2 articles | Viewed by 1294 | Submission Open

Keywords: natural products; sustainable isolation; biological activities; therapeutic potential; structure-activity relationships; omics technologies; bioavailability; functional foods; green chemistry; molecular docking

(This special issue belongs to the Section Bioactives and Nutraceuticals)

New Insights into Epilepsy: From Molecular Physiology to Pathology

edited by Paolo Mainardi

submission deadline 25 Aug 2025 | 1 articles | Viewed by 878 | Submission Open

Keywords: epilepsy; molecular pathology; disease; therapeutic strategies; celluar advance

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Terpenes: Molecular Pharmaceutics and Biotechnology

edited by Lídia Pinheiro and

Célia Faustino

submission deadline 25 Aug 2025 | Viewed by 424 | Submission Open

Keywords: terpenes; antimicrobial; anticancer; anti-inflammatory; drug discovery; drug delivery; flavours; fragrances; biofuels; biocatalysis; bioremediation

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Degradable Polymers: Synthesis, Applications, and Environmental Impact

edited by Ce Sun and

Haiyang Gao

submission deadline 25 Aug 2025 | Viewed by 135 | Submission Open

Keywords: degradable polymer; synthesis; degradation mechanisms; sustainability

(This special issue belongs to the Section Macromolecules)

CRISPR/Cas Systems and Genome Editing—3rd Edition

edited by

Dmitry Karpov

submission deadline 25 Aug 2025 | Viewed by 131 | Submission Open

Keywords: CRISPR/Cas; bacterial argonauts; transcription regulation; genome editing; genome editing tools

(This special issue belongs to the Section Molecular Genetics and Genomics)

Obesity: Different Perspectives Based on Molecular Physiology and Pathology

edited by Hector I. Rocha-Gonzalez

submission deadline 25 Aug 2025 | Viewed by 129 | Submission Open

Keywords: obesity; rational management; perspectives; new ideas; pharmacology; lifestyle modification; molecular advances

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Diagnosis and Treatments of Diabetes Mellitus: 2nd Edition

edited by

Mihail Virgil Boldeanu

submission deadline 25 Aug 2025 | Viewed by 120 | Submission Open

Keywords: metabolic disorders; diabetes mellitus; inflammation; neurotransmitter; inflammatory biomarkers; molecular target; molecular diagnostics; therapeutics; insulin resistance

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Metabolic Regulators of Bone Health

edited by

Akkouch Adil

submission deadline 25 Aug 2025 | Viewed by 113 | Submission Open

Keywords: bone; osteoporosis; diabetes; obesity; glucose; insulin; lipids; estrogen; microRNA; osteoblasts

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Molecular Research on Dyslipidemia

edited by

Aleksandra Zeljkovic

and

Jelena Vekić

submission deadline 25 Aug 2025 | Viewed by 107 | Submission Open

Keywords: dyslipidemia; chronic non-communicable diseases; dysregulation of lipid homeostasis; genetic and epigenetic regulation; lipidomics in personalized medicine; lipid biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in the Role of Retinoic Acid-Regulated Genes in Cancer Biology

edited by Fuming Tsai

submission deadline 25 Aug 2025 | Viewed by 82 | Submission Open

Keywords: retinoic acid; retinoic acid receptors; retinoic x receptors; tumorigenesis; metastasis; tumor microenvironment; molecular pathways

(This special issue belongs to the Section Molecular Genetics and Genomics)

Advances in Lung Cancer: From Genetic Landscape to Treatment

edited by Rossella Bruno

submission deadline 26 Aug 2025 | 1 articles | Viewed by 2168 | Submission Open

Keywords: lung cancer; precision medicine; predictive biomarkers; resistance mechanisms; targeted therapy; immunotherapy; molecular tests; liquid biopsy

(This special issue belongs to the Section Molecular Oncology)

Recent Research on Optoelectronic Materials

edited by

Meysam Tayebi

submission deadline 28 Aug 2025 | Viewed by 204 | Submission Open

Keywords: photoelectrochemistry; optoelectronic materials; perovskite materials; semiconductor interfaces; molecular-level catalysis; solar fuel conversion; nanostructured materials; light-harvesting systems

(This special issue belongs to the Section Materials Science)

Mechanistic Insights into Pharmacological and Non-Pharmacological Pain Therapies: From Cellular Responses to Therapy Outcomes

edited by

Sungtae Koo

submission deadline 28 Aug 2025 | Viewed by 168 | Submission Open

Keywords: neuromodulation; neural plasticity; glial activation; endogenous pain modulation; neuroinflammation; therapeutic mechanisms

(This special issue belongs to the Section Molecular Pharmacology)

Recent Advances in Molecular Pharmacology of Neurological Diseases

edited by

Chian Ju Jong

submission deadline 28 Aug 2025 | Viewed by 143 | Submission Open

Keywords: neurological diseases; neurodevelopmental disorders; neurodegenerative diseases; therapeutic agents; drug discovery; molecular pharmacology

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Biology of Plant Disease Resistance

edited by Heewan Kang

submission deadline 28 Aug 2025 | Viewed by 93 | Submission Open

Keywords: Bacillus subtilis; antifungal activity; amino acids; defense genes; molecular mechanisms

(This special issue belongs to the Section Molecular Plant Sciences)

The Neuro and Immune Mechanisms Behind Cannabinoids Effects

edited by