Isolation and Biological Activities of Natural Products: Focus on Molecular Advance

Dear Colleagues,

Natural resources have long served as a critical resource for the discovery of biologically active compounds with potential therapeutic applications. Recent molecular advances have significantly enhanced our understanding of the mechanisms through which these compounds exert their biological effects. This Special Issue highlights the dual focus on sustainable practices for the isolation of bioactive compounds and recent molecular advances in understanding their biological activities, including anti-inflammatory, antioxidant, antimicrobial, anticancer, neuroprotective, anti-aging, and other properties. Coupled with this, the integration of advanced molecular techniques, such as omics technologies, bioinformatics, and high-throughput screening, has enabled a deeper investigation into the structure-activity relationships, bioavailability, and deeper exploration of the mechanisms underlying the biological activities of these biocompounds. Topics covered include cutting-edge methods for sustainable extraction, advances in bioinformatics and omics technologies for bioactivity analysis, and the use of molecular docking and high-throughput screening to predict and enhance bioactivity. In vivo studies are also encouraged to understand the therapeutic effects of natural bioactive compounds. This issue provides a comprehensive overview of how the convergence of sustainability and molecular advances is shaping the future of natural product research, with implications for drug discovery, health food development, and cosmeceuticals.

Dr. Pedro Ferreira
Dr. Patricia Reboredo-Rodríguez
Guest Editors

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