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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Molecular Research of Cartilage: 2nd Edition

edited by

Laura Mangiavini

submission deadline 20 Jun 2025 | 1 articles | Viewed by 1446 | Submission Open

Keywords: articular cartilage; cartilage lesions; tissue engineering; cell therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Novel Insights into Molecular Mechanisms of Pulmonary Pathology

edited by Qiaozhen Liu

submission deadline 20 Jun 2025 | 2 articles | Viewed by 1446 | Submission Open

Keywords: fibrosis; infection; COPD; asthma; IPF; pneumonia; lung cancer; molecular mechanism

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Enantioselective Homogenous Catalysis in the Presence of Small Molecules of Natural Origin

edited by Tomasz Bauer

submission deadline 20 Jun 2025 | 1 articles | Viewed by 1420 | Submission Open

Keywords: homogenous catalysis; ligands derived from small chiral compounds of natural origin; asymmetric organic synthesis

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

The Pathogenesis of Alcohol-Associated Hepatitis and Its Therapies

edited by

Mrigya Babuta

submission deadline 20 Jun 2025 | 1 articles | Viewed by 1420 | Submission Open

Keywords: alcohol-associted hepatitis; acute kidney injury; hepatic encephalopathy; adaptive immune response; innate immune response; neutrophilia

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Voltage-Gated Ion Channels and Human Diseases

edited by María A. Gandini

submission deadline 20 Jun 2025 | 2 articles | Viewed by 1378 | Submission Open

Keywords: channelopathies; voltage gated-ion channels; human diseases; mutations; calcium; sodium; potassium

(This special issue belongs to the Section Molecular Biophysics)

Autophagy and Kidney Diseases

edited by Francesco Reggiani

submission deadline 20 Jun 2025 | 1 articles | Viewed by 1372 | Submission Open

Keywords: autophagy; kidney diseases; cellular homeostasis; molecular signaling; autophagy biomarkers; renal homeostasis; autophagy modulators

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Statistical Approaches to Omics Data: Searching for Biological Truth

edited by

Alfonso Olaya Abril

submission deadline 20 Jun 2025 | 1 articles | Viewed by 1345 | Submission Open

Keywords: omics; statistics; hypothesis contrast; statistical confidence

(This special issue belongs to the Section Molecular Informatics)

In Silico Methods of Assessing the Therapeutic Potential of Natural Substances

edited by

Radosław Zajdel

and

Anna Merecz-Sadowska

submission deadline 20 Jun 2025 | 2 articles | Viewed by 1296 | Submission Open

Keywords: in silico screening; natural products; molecular docking; computational drug discovery; QSAR modeling; molecular dynamics simulations; natural compounds; drug-target interactions; virtual screening; structure-activity relationships; computational chemistry; cheminformatics; ADMET prediction; bioinformatics; phytochemicals; machine learning in drug discovery; computer-aided drug design; pharmacophore modeling; natural therapeutics; computational pharmacology

(This special issue belongs to the Section Molecular Informatics)

Molecular Advances in Burn and Wound Healing

edited by

Alisha R. Oropallo

submission deadline 20 Jun 2025 | 1 articles | Viewed by 1206 | Submission Open

Keywords: burn; wound; molecular mechanisms; cell signaling; growth factors; cytokines; extracellular matrix; angiogenesis; healing

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Analytical Methods in Biomedical and Environmental Applications: A Molecular Approach (2nd Edition)

edited by

Monica Florescu

submission deadline 20 Jun 2025 | 2 articles | Viewed by 1187 | Submission Open

Keywords: analytical methods; molecular; delivery systems; controlled release; diagnosis; treatment; medicine; food; crop yield; food additives; functional ingredients; environment

(This special issue belongs to the Section Molecular Biophysics)

Advanced Research of Gut Microbiota and Toxins

edited by

Soonjae Hwang

submission deadline 20 Jun 2025 | 1 articles | Viewed by 1158 | Submission Open

Keywords: gut microbe; toxins; gut commensal; infectious disease; gut microbiota; gut microbiome; inflammatory diseases; colon cancer

(This special issue belongs to the Section Molecular Microbiology)

Molecular Insights in Hepatological Complications

edited by

Krzysztof Domagalski

submission deadline 20 Jun 2025 | 1 articles | Viewed by 1140 | Submission Open

Keywords: hepatological complication; hepatitis; liver fibrosis; hepatic steatosis; cirrhosis; cholestasis; hepatocellular carcinoma; signaling pathways; molecular mechanisms; genetic markers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Genetic and Molecular Mechanisms of Obesity

edited by

Maria Elisabeth Street

and

Giuseppina Rosaria Umano

submission deadline 20 Jun 2025 | Viewed by 1056 | Submission Open

Keywords: obesity; insulin signal transduction; insulin sensitivity; co-morbidities; genetics; epigenetics; miRNAs; DNA methylation; molecular mechanisms

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Nanoparticles for Cancer Treatment

edited by Stefano Fedeli

submission deadline 20 Jun 2025 | 1 articles | Viewed by 1040 | Submission Open

Keywords: cancer treatments; nanomedicine; biocompatible polymers; drug-delivery; nanoparticles; bio-orthogonal chemistry; nanomaterials; gold nanoparticles; biodegradable polymers; tumor

(This special issue belongs to the Section Molecular Nanoscience)

Recent Advances in Hypertension and Cardiovascular Disease: 2nd Edition

edited by Edyta Zbroch

submission deadline 20 Jun 2025 | 1 articles | Viewed by 1025 | Submission Open

Keywords: hypertension; hypertension pathophysiology; hypertension molecular mechanisms; cardiovascular disease; cardiovascular pathophysiology; cardiovascular molecular mechanisms; cardiovascular biomarkers; heart failure; coronary artery disease; chronic kidney disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Roles of Phytochemicals and Antioxidants in Colon Cancers

edited by

Nunzio Antonio Cacciola

, Francesca Borrelli and

Paola De Cicco

submission deadline 20 Jun 2025 | 1 articles | Viewed by 983 | Submission Open

Keywords: colon cancer; colorectal cancer; natural products; drug-resistant; phytochemicals; antioxidants; cellular and molecular mechanisms; anti-cancer activity; prevention; treatments

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Modelling in Material Science

edited by

Aggelos Avramopoulos

and

Filippos Sofos

submission deadline 20 Jun 2025 | 1 articles | Viewed by 967 | Submission Open

Keywords: molecular materials; molecular structure; molecular modelling; material design

(This special issue belongs to the Section Materials Science)

Intestinal 3D Culture, Organoids and Gut-on-Chip in Intestinal Disorders

edited by

Vanessa D’Antongiovanni

and

Carolina Pellegrini

submission deadline 20 Jun 2025 | 1 articles | Viewed by 949 | Submission Open

Keywords: 3D cultures; gut-on-chip; intestinal organoids; spheroids; organotypic cultures; morphological studies; pharmacological studies; intestinal cancer; inflammatory bowel disease; intestinal functional disorders

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Computational and Functional Genomics-Based Research on Phytomelatonin

edited by

Nkulu Kabange Rolly

submission deadline 20 Jun 2025 | Viewed by 947 | Submission Open

Keywords: computational genomics; metabolomics and stress tolerance; phytomelatonin; nitric oxide signaling; melatonin; transcriptome analysis; phenomics; proteomics; post-transcriptional modification (PTM); genome-wide melatonin-mediated cell signaling and interactome; melatonin- and plant growth-promoting rhizobacteria

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Biosensors: Latest Applications and Future Perspectives

edited by Júlia Magalhães

submission deadline 20 Jun 2025 | Viewed by 919 | Submission Open

Keywords: bioreceptor; healthcare; environmental monitoring; food safety; point-of-care diagnostics; transducer materials; biosensor design; sensitivity improvement

(This special issue belongs to the Section Molecular Nanoscience)

Functional Genomics of Insects: Unraveling Genetic Mechanisms and Applications

edited by

Bin Li

submission deadline 20 Jun 2025 | 2 articles | Viewed by 897 | Submission Open

Keywords: genomics; comparative genomics; gene regulation networks; developmental biology; metamorphosis; vector biology; insecticide resistance mechanisms; insect– plant interactions; environmental adaptation

(This special issue belongs to the Section Molecular Genetics and Genomics)

A Commemorative Issue in Honor of Professor Peter A. Ward: World Expert in Sepsis

edited by Peter Ward

submission deadline 20 Jun 2025 | 1 articles | Viewed by 889 | Submission Open

Keywords: sepsis; neutrophils; macrophages; histones; chemical modifications; apoptosis; complement factors

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advanced Molecular Research of Gynecological Cancer

edited by

Suryavathi Viswanadhapalli

submission deadline 20 Jun 2025 | 1 articles | Viewed by 833 | Submission Open

Keywords: molecular research; gynecological cancers; ovarian cancer; cervical cancer; uterine cancer; endometrial cancer

(This special issue belongs to the Section Molecular Oncology)

The Importance of Molecular Circadian Rhythms in Health and Disease

edited by

Telma Quintela

and

Diana Rita Barata Costa

submission deadline 20 Jun 2025 | Viewed by 831 | Submission Open

Keywords: molecular clock; circadian dysfunction; health; chronotherapy; circadian rhythms

(This special issue belongs to the Section Molecular Biology)

Cellular and Molecular Biology of Glial Cells

edited by Andrew J. Steelman

submission deadline 20 Jun 2025 | 1 articles | Viewed by 789 | Submission Open

Keywords: microglia; astrocytes; oligodendrocytes; metabolism; homeostasis; neuroinflammation; pathology

(This special issue belongs to the Section Molecular Neurobiology)

Antimicrobial Peptides in Preterm Birth

edited by

Ga-Hyun Son

submission deadline 20 Jun 2025 | 1 articles | Viewed by 778 | Submission Open

Keywords: antimicrobial peptides; preterm birth; molecular mechanisms; microbiome; immune system

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanism and Treatment of Hemangioma

edited by Jaesung P. Choi

submission deadline 20 Jun 2025 | 1 articles | Viewed by 687 | Submission Open

Keywords: hemangioma; angioma; cavernoma; vascular diseases; benign tumor; small vessels

(This special issue belongs to the Section Molecular Oncology)

Molecular Mechanisms Regulating Plant Development and Cell Function

edited by

Tarek Alshaal

submission deadline 20 Jun 2025 | Viewed by 674 | Submission Open

Keywords: cell function; cell polarity; tissue organization; transporter; localization

(This special issue belongs to the Section Molecular Plant Sciences)

Sulfur-Containing Compounds: Synthesis, Characterization and Antimicrobial or Anticancer Activity

edited by

Paola Bonaccorsi

Chiara Maria Antonietta Gangemi

and

Anna Barattucci

submission deadline 20 Jun 2025 | Viewed by 658 | Submission Open

Keywords: sulfurated compounds; sulfoxides; disulfides; sulfides; thiosulfinates; xanthates; antibacterial; antivirus; anticancer; antimicrobial

(This special issue belongs to the Section Biochemistry)

The Biogenesis, Structure, Function and Division of Plastids

edited by

Xiaomin Liu

and Li'na Yin

submission deadline 20 Jun 2025 | Viewed by 643 | Submission Open

Keywords: plastid; chloroplast; chlorophyll; endosymbiotic cyanobacteria; photosynthesis; genetic engineering

(This special issue belongs to the Section Biochemistry)

Medicinal Plants for Tumor Treatments

edited by

Jean-Marc A. Lobaccaro

and

Anne Vejux

submission deadline 20 Jun 2025 | Viewed by 603 | Submission Open

Keywords: oncology; plant extracts; ethnobotany; tumor treatment; molecular characterization; chemical purification; pharmacology

(This special issue belongs to the Section Molecular Plant Sciences)

Leukemia and Lymphoma: A Focus on Molecular Genetics Research

edited by

Grzegorz Przybylski

submission deadline 20 Jun 2025 | Viewed by 602 | Submission Open

Keywords: genomic; leukemia; lymphoma; molecular; pathogenesis

(This special issue belongs to the Section Molecular Oncology)

Gene-Level Pharmacological Research on Natural Products

edited by

Wansu Park

submission deadline 20 Jun 2025 | Viewed by 579 | Submission Open

Keywords: natural products; gene-level pathways; pharmacological efficacy

(This special issue belongs to the Section Molecular Pharmacology)

Coenzyme Q in Health and Disease

edited by Patrick Orlando and

Fabio Marcheggiani

submission deadline 20 Jun 2025 | Viewed by 573 | Submission Open

Keywords: CoQ deficiency; aging; physical exercise; CoQ bioavailability; CoQ biosynthesis; neurodegenerative disease; fertility; cardiovascular disease; mitochondrial dysfunction; inflammation; sarcopenia; mitochondrial dynamics

(This special issue belongs to the Section Biochemistry)

Current Advances in Antivirals and Vaccines

edited by

Nuno Taveira

submission deadline 20 Jun 2025 | Viewed by 573 | Submission Open

Keywords: disease prevention; pandemic control; treatment of existing infections; antiviral resistance; global health equity; herd immunity; preparedness for emerging threats

(This special issue belongs to the Section Molecular Microbiology)

Role of Cell Metabolism in Cancer Biology

edited by

Silvia Filippi

submission deadline 20 Jun 2025 | Viewed by 544 | Submission Open

Keywords: cancer cells metabolism; target therapy; PI3K/Akt/mTOR pathway; hypoxia

(This special issue belongs to the Section Molecular Oncology)

Computational Modelling at the Blood–Brain Barrier

edited by Christian Jorgensen

submission deadline 20 Jun 2025 | Viewed by 537 | Submission Open

Keywords: blood– brain barrier models; molecular dynamics simulations; artificial intelligence; CNS penetration predictive models; asymmetric membranes; efflux pumps

(This special issue belongs to the Section Molecular Neurobiology)

Advances in Chemical Bond and Bonding (3rd Edition)

edited by

Mihai V. Putz

submission deadline 20 Jun 2025 | Viewed by 533 | Submission Open

Keywords: atoms-in-molecules and chemical epistemology; bio-chemical and ligand– receptor interactions; carbon structures and bonding; chemical bonding and nanochemistry; chemical graph theory and chemical topology; electronegativity and chemical reactivity; computational and quantum chemistry; crystallography and solid-state chemistry; sustainable materials

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

The Role of Red Blood Cell Hemodynamic Functionality in Health and Disease

edited by Saul Yedgar and

Gregory Barshtein

submission deadline 20 Jun 2025 | Viewed by 533 | Submission Open

Keywords: red blood cells; RBC flow-affecting properties; RBC deformability; RBC aggregation; RBC adherence; RBC fragility; blood circulation disorders; blood transfusion

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

RNA Editing/Modification in Health and Disease

edited by Valeriana Cesarini and

Piergiorgio La Rosa

submission deadline 20 Jun 2025 | Viewed by 528 | Submission Open

Keywords: RNA editing; RNA transport and localization; miRNAs; siRNAs; lncRNAs

(This special issue belongs to the Section Molecular Genetics and Genomics)

Chronic Kidney Disease: From Molecular Mechanisms to Therapeutic Approaches

edited by

Ligia Petrica

submission deadline 20 Jun 2025 | 1 articles | Viewed by 516 | Submission Open

Keywords: genetics; epigenetics; inflammation; metabolomics; oxiative stress

(This special issue belongs to the Section Molecular Biology)

Aquaporins in Brain Disease, 2nd Edition

edited by

Pablo García-Miranda

and

Miriam Echevarría

submission deadline 20 Jun 2025 | Viewed by 515 | Submission Open

Keywords: edema; hydrocephalus; NMO; neurodegenerative diseases; iNPH; CSF; glymphatic system; brain tumors

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research on Cancer Stem Cells

edited by

Sabrina Battista

submission deadline 20 Jun 2025 | Viewed by 506 | Submission Open

Keywords: self-renewal; microenvironment; plasticity; epigenetics; epithelial-mesenchymal transition; heterogeneity; targeting; dormancy

(This special issue belongs to the Section Biochemistry)

Neuroimmune Axis in Cancer and Inflammatory Diseases

edited by

Patrick Ming-Kuen Tang

submission deadline 20 Jun 2025 | Viewed by 490 | Submission Open

Keywords: neuro-immune axis; cancer progression; drug resistance; cancer therapy

(This special issue belongs to the Section Molecular Oncology)

Molecular Mechanisms of Primary Graft Dysfunction and Acute Rejection in Solid Organ Transplantation

edited by

Emilia Lecuona

submission deadline 20 Jun 2025 | Viewed by 475 | Submission Open

Keywords: transplant; graft dysfunction; ischemia– reperfusion injury; DAMPs; immune cells; allo-antigens; acute rejection; metabolism; cell death; MHC; PRRs

(This special issue belongs to the Section Molecular Immunology)

Recent Advances in Biomolecular Recognition: 3rd Edition

edited by

Ray Luo

submission deadline 20 Jun 2025 | Viewed by 471 | Submission Open

Keywords: proteins; nucleic acids; membrane; ligand; binding

(This special issue belongs to the Section Molecular Biophysics)

Chemical Tools for Microbial Functionalization: Bridging Organic Chemistry and Biotechnology

edited by Stefania Cicco and

Danilo Vona

submission deadline 20 Jun 2025 | Viewed by 457 | Submission Open

Keywords: organometallic biochemistry; green chemistry; bioorthogonal; living polymers; living functionalization; hybrid materials

(This special issue belongs to the Section Molecular Microbiology)

Progress in New Agents to Treat Breast Cancer

edited by Eileen Brantley

submission deadline 20 Jun 2025 | Viewed by 454 | Submission Open

Keywords: breast cancer; chemotherapeutic agents; DNA-alkylating drugs; anthracyclines; antimetabolites; taxanes

(This special issue belongs to the Section Molecular Oncology)

Pathophysiology of Hair Loss

edited by

Kwang-Hyun Park

submission deadline 20 Jun 2025 | Viewed by 433 | Submission Open

Keywords: Hair Loss; Pathophysiology; Molecular Mechanisms; Genetic Mutations; Signaling Pathways; Nutrient Interactions; Personalized Therapies; Targeted Drug Delivery

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Exploring the Therapeutic Potential of Modulators of Regulated Cell Death for Retinal Atrophy

edited by Marcelo Nociari

submission deadline 20 Jun 2025 | Viewed by 420 | Submission Open

Keywords: Stargardt disease; dry-age related macular degeneration; cell death; atrophy; regulated necrosis; apoptosis; autophagy; proteostasis; lipofuscin

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Displaying special issue 751-800 on page 16 of 68.

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