RNA Editing/Modification in Health and Disease
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Genetics and Genomics".
Deadline for manuscript submissions: 20 December 2025 | Viewed by 802
Special Issue Editors
Interests: cancer
Interests: neurodegenerative diseases; neurodevelopment; oxidative stress
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
RNA editing, RNA modifications, and RNA metabolism are dynamic players in health and disease, shaping cellular responses and molecular diversity. They play crucial roles in various cellular processes, impacting gene expression, RNA stability, and protein diversity. These mechanisms are essential for maintaining cellular homeostasis and the proper functioning of biological pathways. The dysregulation of these processes can lead to disease states, including cancer, neurodegenerative disorders, and autoimmune conditions. The specific mechanisms and consequences of RNA editing, RNA modifications, and RNA metabolism are constantly under investigation to better understand and potentially target these processes for therapeutic purposes.
This Special Issue welcomes contributions that broaden our understanding of the role played by RNA editing, modifications, and metabolism in physiological processes and diseases.
Potential topics may include, but are not limited to, the following:
- RNA editing—adenosine-to-inosine (A-to-I) RNA editing and cytosine-to-uracil (C-to-U) RNA editing;
- N6-methyladenosine (m6A);
- Pseudouridine (Ψ);
- 5-methylcytosine (m5C);
- Ribose 2’-O-methylation (2’-O-Me);
- RNA splicing and alternative splicing mechanisms;
- RNA degradation pathways and their regulation;
- RNA transport and localization;
- RNA–protein interactions and their functional implications;
- Non-coding RNA metabolism, including miRNAs, siRNAs, and lncRNAs.
Dr. Valeriana Cesarini
Dr. Piergiorgio La Rosa
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- RNA editing
- RNA transport and localization
- miRNAs
- siRNAs
- lncRNAs
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