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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Synthesis, Characterization and Applications of Advanced Polymer Materials

edited by Namil Kim

submission deadline 31 Jan 2027 | 2 articles | Viewed by 2600 | Submission Open

Keywords: synthesis methodologies; molecular architecture; functional polymers; characterization techniques; cutting-edge applications

(This special issue belongs to the Section Macromolecules)

RNA in Biology and Medicine (2nd Edition)

edited by

Roberto Patarca

and William A. Haseltine

submission deadline 31 Jan 2027 | 3 articles | Viewed by 2562 | Submission Open

Keywords: noncoding RNAs; coding RNAs; RNA-based therapy; RNA vaccine; RNA structure; RNA function

(This special issue belongs to the Section Molecular Biology)

Systemic Lupus: Molecular Research, New Biomarkers and Novel Therapy

edited by Juan Pablo Mackern-Oberti

submission deadline 31 Jan 2027 | 2 articles | Viewed by 2546 | Submission Open

Keywords: lupus; biomarkers; autoimmunity; inflammation; therapy; treatment; endocrine; prolactin; stress; T cell and B cell activation; T cell and B cell proliferation; antigenic immunosuppression

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Perspectives in Lung Diseases: Pathogenesis, Diagnosis, and Treatment—2nd Edition

edited by

Elena Levantini

submission deadline 31 Jan 2027 | 3 articles | Viewed by 2538 | Submission Open

Keywords: lung cancer models; cancer stem cells; tumor microenvironment; targeted therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Electromagnetic Field Interactions with Biomolecules

edited by

Svetlana Jovanović

submission deadline 31 Jan 2027 | 1 articles | Viewed by 2492 | Submission Open

Keywords: nonionizing electromagnetic fields; biomolecules; proteins; oxidative stress; Fe metabolism; amyloid-β peptide

(This special issue belongs to the Section Materials Science)

Molecular Modeling in Pharmaceutical Sciences

edited by

Maciej Spiegel

submission deadline 31 Jan 2027 | 3 articles | Viewed by 2446 | Submission Open

Keywords: molecular modeling; computer-aided drug design; molecular docking; drug discovery; quantum chemistry; molecular dynamics simulations; virtual screening; computational pharmacology; pharmacy; in silico methods

(This special issue belongs to the Section Molecular Pharmacology)

Cellular Memory in Response to Environmental Conditions

edited by

Satoshi Kishigami

submission deadline 31 Jan 2027 | 1 articles | Viewed by 2425 | Submission Open

Keywords: cellular memory; cellular environment; embryonic development; epigenetics; transgenerational inheritance; mammals; DOHaD

(This special issue belongs to the Section Molecular Biology)

Plants Redox Biology

edited by

Xin Li

submission deadline 31 Jan 2027 | 1 articles | Viewed by 2389 | Submission Open

Keywords: plant–environment interaction; stress physiology; plant redox signaling; plant hormones; plant–pathogen interaction; reactive oxygen species (ROS); reactive nitrogen species (RNS); ascorbate; flavonoid; glutathione

(This special issue belongs to the Section Molecular Plant Sciences)

In Silico Approaches to Unravelling Toxicity Mechanisms in Molecular Drugs

edited by

Yoshihiro Uesawa

submission deadline 31 Jan 2027 | 1 articles | Viewed by 2373 | Submission Open

Keywords: cheminformatics; in silico analysis; QSAR; toxicity prediction; machine learning; toxicity mechanisms; omics data integration; toxicity biomarkers; artificial intelligence; adverse event database

(This special issue belongs to the Section Molecular Pharmacology)

Pharmacological Effects of Bioactive Compounds Derived from Plants

edited by

Ibrahim Mssillou

submission deadline 31 Jan 2027 | 3 articles | Viewed by 2361 | Submission Open

Keywords: bioactive compounds; wound healing; anti-cancer; anti-inflammatory; mechanism of action; antioxidants; neuroprotection; pharmacological properties

(This special issue belongs to the Section Bioactives and Nutraceuticals)

New Advances in Amyotrophic Lateral Sclerosis

edited by

Vacchiano Veria

submission deadline 31 Jan 2027 | 1 articles | Viewed by 2323 | Submission Open

Keywords: genetics and epigenetics; biomarkers; nutrition and metabolism; TDP-43 pathology; advanced model of ALS

(This special issue belongs to the Section Molecular Neurobiology)

Analysis on Effector and Regulatory Molecules in Renal Diseases

edited by

Takashi Oda

submission deadline 31 Jan 2027 | 2 articles | Viewed by 2322 | Submission Open

Keywords: effector molecules; regulatory molecules; membrane attack complex (MAC); perforin; granzyme; immune complex; neutrophil extracellular traps (NETs); proteolytic enzymes; reactive oxygen species; infection-related glomerulonephritis (IRGN); nephritis-associated plasmin receptor (NAPlr); streptococcal pyrogenic exotoxin B (SPEB); adhesion molecules

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Current and Emerging Therapeutic Approaches for MASLD

edited by

Chrysoula Boutari

submission deadline 31 Jan 2027 | 1 articles | Viewed by 2307 | Submission Open

Keywords: MASLD; MASH; GLP-1 agonists; anti-inflammatory agents; anti-obesity drugs; FGF-21

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Multi-Target and Synergistic Therapeutic Strategies in Modern Drug Discovery

edited by

Vincenzo Piccolo

submission deadline 31 Jan 2027 | 2 articles | Viewed by 2240 | Submission Open

Keywords: multi-target and synergistic therapeutic strategies; drug design; combination therapy; polypharmacology; drug re-purposing

(This special issue belongs to the Section Molecular Pharmacology)

Computer-Aided Drug Discovery: Computational Chemistry and Cheminformatics

edited by

Daniel Glossman-Mitnik

submission deadline 31 Jan 2027 | 4 articles | Viewed by 2239 | Submission Open

Keywords: computer-aided drug discovery; computational chemistry; cheminformatics; conceptual density functional theory (CDFT); molecular docking; molecular dynamics simulations; QSAR/QSPR modeling; ADMET prediction; machine learning in drug design

(This special issue belongs to the Section Molecular Informatics)

Molecular Perspective on Skeletal Muscle Regeneration

edited by Xuhui Liu

submission deadline 31 Jan 2027 | 1 articles | Viewed by 2165 | Submission Open

Keywords: skeletal muscle regeneration; satellite cells; stem cell niche; fibro/adipogenic progenitors; aging; muscle stem cells; cell–cell interactions; fibrosis and fatty infiltration; translational therapeutics

(This special issue belongs to the Section Molecular Biology)

Progression of Innate Immunity in Tuberculosis Infections

edited by

Octavio Miguel Rivero-Lezcano

submission deadline 31 Jan 2027 | 2 articles | Viewed by 2151 | Submission Open

Keywords: macrophage; neutrophil; innate lymphoid cells; NK cells; mucosal associated invariant T (MAIT) cells; phagocytosis; trained innate immunity; collectins; autophagy; mucociliary clearance; NETosis

(This special issue belongs to the Section Molecular Immunology)

Molecular and Bioactive Properties of Novel and Functional Food Ingredients

edited by

Ewelina Zielińska

submission deadline 31 Jan 2027 | 2 articles | Viewed by 2097 | Submission Open

Keywords: functional food; bioactive compounds; novel food; molecular properties; peptides; edible insects; metabolomics; health-promoting ingredients; oxidative stress

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Structure and Function of Subcellular Organelle and Protein-Membrane Systems

edited by

Chikara Sato

submission deadline 31 Jan 2027 | 2 articles | Viewed by 2057 | Submission Open

Keywords: immuno-electron microscopy; cell signaling; comparative anatomy; diagnosis; molecular recognition; molecular complexes; electro-chemistry; liquid-phase synthesis; metal sedimentation; membrane endoskeleton

(This special issue belongs to the Section Molecular Biophysics)

Advances in Protein Structure and Dynamics

edited by

Ki Hyun Nam

submission deadline 31 Jan 2027 | 3 articles | Viewed by 2022 | Submission Open

Keywords: experimental protein structure determination; structure–function relationships and mechanistic enzymology; molecular dynamics simulations; conformational dynamics, intrinsic disorder, and structural flexibility; protein–ligand and protein–protein interactions; AI-predicted structures with experimental and simulation data; methodological developments in structural and dynamic analysis.

(This special issue belongs to the Section Molecular Biophysics)

Heterocyclic Compounds: Molecular Modelling Studies and Pharmacological Investigation

edited by

Gabriella Guerrini

and

Maria P. Giovannoni

submission deadline 31 Jan 2027 | 1 articles | Viewed by 2014 | Submission Open

Keywords: heterocycles; fused heteocycles; synthesis; small-molecules; natural product; drug design; biological studies; molecular modeling

(This special issue belongs to the Section Biochemistry)

Unknown Pathogenesis of Musculoskeletal Diseases and Basic Sciences: The Role of New Technologies

edited by

Gianluigi Pasta

submission deadline 31 Jan 2027 | 1 articles | Viewed by 1956 | Submission Open

Keywords: AI; musculoskeletal diseases; pathogenesis; basic sciences; molecular mechanisms; genetics; immunology; biomechanics; translational research; experimental models; tissue engineering

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Role of Proteomics in Human Diseases and Infections: 2nd Edition

edited by

Mahamud Ur Rashid

submission deadline 31 Jan 2027 | 3 articles | Viewed by 1905 | Submission Open

Keywords: proteomics; human diseases; infections; biomarkers; therapeutic targets; disease pathogenesis; host–pathogen interactions; diagnostic tools

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Development of Responsive Nanoparticles for Cancer Therapy, 3rd Edition

edited by

Jordi Puiggalí

submission deadline 31 Jan 2027 | 1 articles | Viewed by 1878 | Submission Open

Keywords: nanoparticles; liposomes; polymersomes; micelles; surface functionalization; cell targeting; stimuli-sensitivity; drug delivery; therapeutic applications; diagnostic applications; cancer treatment

(This special issue belongs to the Section Molecular Nanoscience)

Role of Glia in Human Health and Disease—2nd Edition

edited by

Daniele Lana

submission deadline 31 Jan 2027 | 2 articles | Viewed by 1830 | Submission Open

Keywords: astrocytes; microglia; oligodendrocytes; Schwann cells; neurodegeneration

(This special issue belongs to the Section Molecular Neurobiology)

Metabolic Features of Breast Cancer: From Understanding Heterogeneous Biology to Developing New Therapies

edited by

Lyudmila Bel'skaya

submission deadline 31 Jan 2027 | 2 articles | Viewed by 1822 | Submission Open

Keywords: breast cancer; heterogeneity; metabolic processes; metabolites; proteins; gene expression; diagnosis; prognosis; treatment response

(This special issue belongs to the Section Molecular Oncology)

Novel Genotypes and Experimental Advances in Xenotransplantation

edited by Konrad Fischer

submission deadline 31 Jan 2027 | 1 articles | Viewed by 1765 | Submission Open

Keywords: xenotransplantation; genetic engineering; preclinical models; genetically modified donor organs

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Biomarkers in Oral Pathology

edited by

Ioannis Astreidis

and Konstantinos Paraskevopoulos

submission deadline 31 Jan 2027 | 2 articles | Viewed by 1737 | Submission Open

Keywords: oral disease; oral pathology; oral cancer; biomarkers; molecular biomarkers; head and neck pathology; precision medicine; omics-based analysis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Role of Transcription Factors in Antioxidant Pathways

edited by

Eleonora Stanca

submission deadline 31 Jan 2027 | 1 articles | Viewed by 1702 | Submission Open

Keywords: transcription factor; oxidative stress; NRF1/2; NRF3; NFkB; P53; antioxidant-response elements; neurologial diseases; metabolic diseases; cancer

(This special issue belongs to the Section Molecular Biology)

Advances in Targeted Therapy and Immunotherapy for Lung Cancer

edited by

Walid Shalata

submission deadline 31 Jan 2027 | 1 articles | Viewed by 1652 | Submission Open

Keywords: lung cancer; small-cell lung cancer; non-small-cell lung cancer; targeted therapy; immunotherapy

(This special issue belongs to the Section Molecular Oncology)

Thyroid Disorders: From Physiological Regulation to Targeted Cancer Therapy

edited by Lisa Thomasz

submission deadline 31 Jan 2027 | 1 articles | Viewed by 1649 | Submission Open

Keywords: thyroid autoregulation; oxidative stress; iodide excess; sodium-iodide symporter (NIS); thyroid cancer; autoimmune thyroid disease; thyroid tumor microenvironment; dedifferentiation mechanisms; targeted therapies; radionuclide therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Plant Molecular Ecology and Genomic Perspectives

edited by

Peng Zhao

submission deadline 31 Jan 2027 | 4 articles | Viewed by 1648 | Submission Open

Keywords: genome assembly and annotaion; genomic structure and function of plants; plant molecular ecology; genome prediction and GWAS; gene-editing technologies; transcriptomics and metabolomics; nuclear and organelle genomics

(This special issue belongs to the Section Molecular Plant Sciences)

Pathological Changes and Pathogenic Mechanisms of Chronic Liver Disease

edited by Natalia Nuño-Lámbarri

submission deadline 31 Jan 2027 | 1 articles | Viewed by 1618 | Submission Open

Keywords: chronic liver disease; liver fibrosis; cirrhosis; pathogenic mechanisms; inflammation; immune–metabolic interactions; oxidative stress; gut–liver axis; hepatocellular carcinoma; biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular and Electrochemical Mechanisms of Metal Corrosion

edited by

Mehrdad Faraji

submission deadline 31 Jan 2027 | 1 articles | Viewed by 1614 | Submission Open

Keywords: metal corrosion; molecular mechanisms; electrochemistry; surface chemistry; corrosion inhibitors; passivation

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

The Latest Research in Intestinal Inflammation and Immunity

edited by

Gabriela Fonseca-Camarillo

and

Jesús Yamamoto-Furusho

submission deadline 31 Jan 2027 | 2 articles | Viewed by 1603 | Submission Open

Keywords: ulcerative colitis; mucins; inflammation; immunoregulation; T cells; B cells; Crohn’s disease; cytokines

(This special issue belongs to the Section Molecular Immunology)

Plant Growth: Molecular Mechanisms

edited by

Zulfiqar Ali Sahito

and

Afsheen Zehra

submission deadline 31 Jan 2027 | 3 articles | Viewed by 1576 | Submission Open

Keywords: plant growth; hormonal crosstalk; epigenetics; CRISPR/Cas9 genome editing technologies; metabolomics; transcriptomics

(This special issue belongs to the Section Molecular Plant Sciences)

Omics Approaches to Unravel Plant Responses to Habitat Stresses

edited by

Claudia Uhde-Stone

submission deadline 31 Jan 2027 | 1 articles | Viewed by 1513 | Submission Open

Keywords: omics; multi-omics; high-throughput technologies; biotic stress; abiotic stress; environmental stress; crosstalk; translational biology; crop improvement

(This special issue belongs to the Section Molecular Plant Sciences)

Design, Synthesis, and Biological Evaluation of Novel Bioactive Compounds

edited by

Monika Wujec

and

Oleg M. Demchuk

submission deadline 31 Jan 2027 | 1 articles | Viewed by 1494 | Submission Open

Keywords: drug design; organic compounds; heterocyclic compounds; synthetic methodologies; medicinal chemistry; bioactive molecules; pharmaceutical applications; structure–activity relationships (SARs); organic synthesis; natural product

(This special issue belongs to the Section Molecular Pharmacology)

Natural Antioxidants—Sources, Characteristics, and Biological Activity

edited by

Maciej Spiegel

submission deadline 31 Jan 2027 | 1 articles | Viewed by 1489 | Submission Open

Keywords: natural antioxidants; oxidative stress; reactive oxygen species; inflammation; free radicals; structure–activity relationship; nutraceuticals; synergistic effects; plant-derived compounds; drug discovery

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Mechanisms of Cardiac Development and Disease (Second Edition)

edited by

Kay-Dietrich Wagner

submission deadline 31 Jan 2027 | 1 articles | Viewed by 1459 | Submission Open

Keywords: cardiac development; cardiac repair; regeneration; cardiac cell-cell interaction; fibrosis; remodeling; molecular mechanisms

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms of Human Liver Diseases: 3rd Edition

edited by

Elena Grossini

submission deadline 31 Jan 2027 | 1 articles | Viewed by 1453 | Submission Open

Keywords: non-alcoholic fatty liver disease (NAFLD); non-alcoholic steatohepatitis (NASH); alcoholic steatohepatitis (ASH); Wilson’s disease; hemochromatosis; viral hepatitis; autoimmune hepatitis; hepatocellular carcinoma; signaling pathways; molecular mechanisms; metabolic dysfunction-associated steatotic liver disease (MASLD); metabolic dysfunction-associated steatohepatitis (MASH)

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Application of Stem Cells in Regenerative Medicine

edited by

Marina Gazdic Jankovic

submission deadline 31 Jan 2027 | 1 articles | Viewed by 1447 | Submission Open

Keywords: embryonic stem cells; induced pluripotent stem cells; adult stem cells; cancer stem cells; regenerative medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Exploring the Gut-Brain Axis: Mechanisms and Implications for Health and Disease

edited by

Martina Vincenzi

submission deadline 31 Jan 2027 | 1 articles | Viewed by 1430 | Submission Open

Keywords: gut–brain axis; enteric nervous system; dysbiosis; gut microbiota; neuroinflammation; one health; microbiota–immune crosstalk; metabolic syndromes; cardiovascular diseases; neurodegenerative diseases; cancer

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Novel Advances in Ataxia-Telangiectasia

edited by David Coman

submission deadline 31 Jan 2027 | 2 articles | Viewed by 1392 | Submission Open

Keywords: ataxia-telangiectasia; ATM; metabolism; mitochondrial dysfunction; DNA repair; natural history; biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Bridging Basic and Clinical Science: Shared Molecular and Metabolic Mechanisms in Preeclampsia, Gestational Diabetes and Gestational Weight Gain

edited by

Reyna Sámano

, Hector Borboa-Olivares, Verónica Zaga-Clavellina and

Gabriela Chico-Barba

submission deadline 31 Jan 2027 | 1 articles | Viewed by 1381 | Submission Open

Keywords: preeclampsia; gestational diabetes; gestational weight gain; metabolic mechanisms; molecular pathways; placental biology; maternal–fetal interface; biomarkers; insulin resistance; inflammation; translational research

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecularly Engineered Nanomaterials for Energy Conversion, Storage, and AI-Driven Materials Discovery

edited by

Atanu Jana

submission deadline 31 Jan 2027 | 1 articles | Viewed by 1341 | Submission Open

Keywords: molecular engineering; energy conversion and storage; hydrogen evolution reaction (HER); oxygen evolution reaction (OER); batteries and supercapacitors; optical properties; light-emitting diodes; AI-assisted materials design

(This special issue belongs to the Section Molecular Nanoscience)

Infectious Diseases and Infection Models in Laboratory Animals

edited by

Hiraku Sasaki

and Fumio Ike

submission deadline 31 Jan 2027 | 2 articles | Viewed by 1337 | Submission Open

Keywords: infection model; Infectious diseases in laboratory animals; bacterial infection; viral infection; parasitic infection; molecular diagnosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Thyroid Hormone Signaling: Mechanisms and Pathophysiological Implications

edited by

María Laura Barreiro Arcos

and Horacio Eduardo Romeo

submission deadline 31 Jan 2027 | 1 articles | Viewed by 1321 | Submission Open

Keywords: thyroid hormones; mitochondrial function; oxidative stress; redox signaling; metabolic disorders; immune modulation; cardiovascular pathology; neurodevelopment and aging; cancer progression

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Autophagy in Physiology and Pathophysiology: Recent Advances

edited by

María Isabel Colombo

and Claudio Marcelo Fader

submission deadline 31 Jan 2027 | 2 articles | Viewed by 1267 | Submission Open

Keywords: macroautophagy; microautophagy; chaperone-mediated autophagy (CMA); autophagy-related genes (ATG); xenophagy; mitophagy; pexophagy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Research on Trace Elements in Nutrition and Health

edited by

Jędrzej Proch

submission deadline 31 Jan 2027 | 1 articles | Viewed by 1267 | Submission Open

Keywords: trace elements; molecular mechanisms; micronutrients; supplementation; speciation analysis; biomarkers; health risk assessment

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Displaying special issue 2451-2500 on page 50 of 62.

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