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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Current Trends in Nanophotonics and Molecular-Scale Light Control
edited by Mitradeep Sarkar
submission deadline 27 Feb 2026 | Viewed by 92 | Submission Open
Keywords: nanophotonics; light– matter interaction; metamaterials and 2D materials; photonic crystals; molecular sensing and imaging; quantum and nonlinear optics
(This special issue belongs to the Section Molecular Nanoscience)
Recent Prospects in Neurons
edited by
submission deadline 27 Feb 2026 | Viewed by 88 | Submission Open
Keywords: DNA damage/repair; genetic/epigenetic; 3D genomic; global transcriptome analysis; transgenic animals; neuron polarization/genesis/network; neuro-developmental/psychiatric diseases; brain structures; intelligence/intellectual disability
(This special issue belongs to the Section Molecular Neurobiology)
Lung Diseases Molecular Pathogenesis and Therapy
edited by
submission deadline 28 Feb 2026 | 6 articles | Viewed by 17656 | Submission Open
Keywords: lung diseases; drug therapy; chronic obstructive pulmonary disease; lung cancer; lung fibrosis; pulmonary hypertension; asthma
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Rare Diseases Biomarkers: 2nd Edition
edited by
submission deadline 28 Feb 2026 | 5 articles | Viewed by 17107 | Submission Open
Keywords: orphan diseases; rare diseases; inborn errors of metabolism; mitochondrial disorders; biomarker discovery
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Cell Signaling Pathways and Signal Transduction
edited by Katsuhiko Muraki and
submission deadline 28 Feb 2026 | 6 articles | Viewed by 15647 | Submission Open
Keywords: Ca2+ signaling; transcriptional and post-transcriptional pathways; growth factors; second messengers; cell metabolism; cell senescence; protein phosphorylation/dephosphorylation; membrane trafficking; cell proliferation; differentiation; and apoptosis; cytokine/chemokine signaling
(This special issue belongs to the Section Biochemistry)
Drug Discovery Based on Natural Products
edited by Woo-kyung Kim
submission deadline 28 Feb 2026 | 6 articles | Viewed by 12089 | Submission Open
Keywords: drug discovery; bioactive compounds; pharmacological activities and mechanisms; omics technologies
(This special issue belongs to the Section Molecular Pharmacology)
Anti-Cancer Drugs: Natural Products, Synthetic Compounds and Potential Pharmacological Effects and Applications
edited by Kaiqun Ren and Hui Zou
submission deadline 28 Feb 2026 | 3 articles | Viewed by 7986 | Submission Open
Keywords: cancer; natural product; synthetic compounds; mechanism; structural modification; pharmacological action
(This special issue belongs to the Section Molecular Pharmacology)
Plant–Microbe Interactions: 2nd Edition
edited by Jian Jin
submission deadline 28 Feb 2026 | 6 articles | Viewed by 7698 | Submission Open
Keywords: plant; crop; rhizosphere microbiome; microbial colonization; quorum sensing; endophytic microbes
(This special issue belongs to the Section Molecular Plant Sciences)
The Molecular Role of Platelets in Human Diseases submission deadline 28 Feb 2026 | 3 articles | Viewed by 5478 | Submission Open
Keywords: platelet; biomarkers; platelet membrane proteins; platelet-derived microparticles; platelet-related diseases; thrombosis; inflammatory diseases; cardiovascular disease; cancer; tumor growth and metastasis
(This special issue belongs to the Section Molecular Biology)
Blood Cells in Human Health and Disease
edited by Leonid Livshits
submission deadline 28 Feb 2026 | 4 articles | Viewed by 5346 | Submission Open
Keywords: red blood cell; RBC membrane; RBC biophysical properties; RBC rheology; RBC mechanical properties; RBC membrane vesiculation; RBC clearance; RBC in diabetes; hemoglobinopathies; RBC storage TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian   //   TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //     This page is in English   Translate to Simplified Chinese         Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh   Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com
(This special issue belongs to the Section Biochemistry)
Oral Soft Tissue Repair and Oral Diseases: 2nd Edition
edited by
submission deadline 28 Feb 2026 | 4 articles | Viewed by 5340 | Submission Open
Keywords: oral medicine; tissue regeneration; lasers; photobiomodulation; periodontology; implant dentistry
(This special issue belongs to the Section Molecular Biology)
Molecular Imaging for Cancer Theranostics
edited by and Kai Bao
submission deadline 28 Feb 2026 | 2 articles | Viewed by 4983 | Submission Open
Keywords: molecular imaging; cancer theranostics; precision medicine; targeted therapy; diagnostic imaging; theranostic agents; multimodal imaging; molecular probes
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
New Advances in Nanomedicine Innovation in Cancer Treatment
edited by Tijani Gharbi
submission deadline 28 Feb 2026 | 2 articles | Viewed by 3781 | Submission Open
Keywords: nanotechnology; nanomedicine; radiotherapy; theragnostic; antibody– drug conjugates (ADCs); drug delivery; radiopharmaceutical; gold nanoparticles; nanoparticle– biomolecule conjugate
(This special issue belongs to the Section Molecular Nanoscience)
Advances in Amyloid Aggregation and Its Inhibition: Implementing Insights from Physiological Conditions submission deadline 28 Feb 2026 | 2 articles | Viewed by 3679 | Submission Open
Keywords: protein aggregation; amyloid; physiological conditions; aggregation inhibition; neurodegenerative diseases; amyloidosis
(This special issue belongs to the Section Molecular Neurobiology)
Anti-Inflammatory and Anti-Oxidant Effects of Extracts from Plants submission deadline 28 Feb 2026 | 3 articles | Viewed by 2768 | Submission Open
Keywords: oxidative stress; inflammation; herbal extracts
(This special issue belongs to the Section Bioactives and Nutraceuticals)
New Insights into the Molecular Pathogenesis of Myeloproliferative Neoplasms submission deadline 28 Feb 2026 | 2 articles | Viewed by 2382 | Submission Open
Keywords: myeloproliferative neoplasms; molecular diagnostic; targeted therapy; biomarkers; inflammation
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Network Pharmacology: An Emerging Field in Drug Discovery (2nd Edition)
edited by
submission deadline 28 Feb 2026 | 2 articles | Viewed by 2189 | Submission Open
Keywords: network pharmacology; machine learning; databases; drug discovery; computer-aided drug design (CADD); data mining
(This special issue belongs to the Section Molecular Pharmacology)
Liquid Biopsies in Oncology—3rd Edition submission deadline 28 Feb 2026 | 2 articles | Viewed by 1793 | Submission Open
Keywords: precision oncology; personalized therapy; cancer biomarkers; liquid biopsy; biological fluids; circulating molecules; circulating tumor cells; CTCs; ctDNA; ctRNA; cell-free DNA; cfDNA; NGS; circulating miRNAs; exosomes; extracellular vesicles
(This special issue belongs to the Section Molecular Oncology)
Microbiomes in Human Health and Disease
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 1664 | Submission Open
Keywords: microbiome; dysbiosis; commensal bacteria; pathobiont; metabolites; immune modulation; nutrient metabolism; barrier function; health and disease
(This special issue belongs to the Section Molecular Microbiology)
Molecular Advances in Reproduction and Fertility of Aquatic Animals: 3rd Edition
edited by and Hongtuo Fu
submission deadline 28 Feb 2026 | 2 articles | Viewed by 1657 | Submission Open
Keywords: reproduction; aquatic animals; sex determination; gonadal development; steroid hormones; sex-related genes; monosex culture
(This special issue belongs to the Section Molecular Biology)
Viral Infections: Physiology, Pathophysiology, Pathogenesis, Diagnosis and Treatment, 2nd Edition
edited by and Dominika Marta Stygar
submission deadline 28 Feb 2026 | 2 articles | Viewed by 1624 | Submission Open
Keywords: viral infections; virus mutations; molecular diagnostic methods; antiviral drugs/preparations; viral diseases; physiological mechanisms
(This special issue belongs to the Section Molecular Microbiology)
Innovative Technologies in the Study and Understanding of Colorectal Tumorigenesis: Challenges and Opportunities
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 1262 | Submission Open
Keywords: colorectal cancer; genetic analysis; gut microbiome; tumor; circulating components; medicine; immunotherapy; proteomics
(This special issue belongs to the Section Molecular Oncology)
Damage to Plants and Microorganisms Caused by Heavy Metal Toxicity
edited by
submission deadline 28 Feb 2026 | 2 articles | Viewed by 1219 | Submission Open
Keywords: metal; oxidative stress; stress response; molecular function; gene regulation; metabolic regulation; signaling pathway
(This special issue belongs to the Section Molecular Plant Sciences)
Melanoma: Molecular Diagnosis and Treatment
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 1189 | Submission Open
Keywords: molecular pathology; melanoma; skin cancer; molecular pathway; dermatopathology
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Genetic Advances in Neurobiology of Health and Disease
edited by and Katerina Papanikolopoulou
submission deadline 28 Feb 2026 | 1 articles | Viewed by 1090 | Submission Open
Keywords: genomics; proteins; proteomics; signaling
(This special issue belongs to the Section Molecular Neurobiology)
Oral Diseases: Molecular Research and Novel Therapy
edited by
submission deadline 28 Feb 2026 | Viewed by 1077 | Submission Open
Keywords: oral diseases; molecular mechanisms; inflammation and immunity; redox signalling
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Current Trends and Future Directions in Antimicrobial Peptide Research
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 953 | Submission Open
Keywords: antimicrobial peptides (AMPs); host defense; structure-function; antimicrobial agents; biomedical applications; antibiotic alternatives; antibiotic resistance
(This special issue belongs to the Section Molecular Biology)
Advances in Natural Antioxidants in Human Health and Diseases
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 918 | Submission Open
Keywords: oxidative stress and diseases; antioxidants; natural products
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular Biology of Foodborne Pathogens: Genomics, Resistance, and New Perspectives
edited by
submission deadline 28 Feb 2026 | Viewed by 916 | Submission Open
Keywords: foodborne pathogens; antibiotic resistance; virulence factor; virulence genes; gene expression; bioinformatics; whole geomic sequencing
(This special issue belongs to the Section Molecular Microbiology)
Cardiovascular and Metabolic Pharmacology
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 901 | Submission Open
Keywords: cardiovascular pharmacology; metabolic pharmacology; hypertension; diabetes; obesity; atherosclerosis; hyperlipidemias; heart failure
(This special issue belongs to the Section Molecular Pharmacology)
New Advances in Amyotrophic Lateral Sclerosis
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 861 | Submission Open
Keywords: genetics and epigenetics; biomarkers; nutrition and metabolism; TDP-43 pathology; advanced model of ALS
(This special issue belongs to the Section Molecular Neurobiology)
New Trends in Diabetes, Hypertension and Cardiovascular Diseases: 4th Edition submission deadline 28 Feb 2026 | 2 articles | Viewed by 837 | Submission Open
Keywords: cardiovascular disease; myocardial infarction; stroke; transient ischemic attack; hypertension; diabetes mellitus; atherosclerosis; inflammation
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Advances and Views in Triple-Negative Breast Cancer
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 820 | Submission Open
Keywords: breast cancer; molecular biology; personalized medicine; triple-negative breast cancer
(This special issue belongs to the Section Molecular Oncology)
The Differential Role of B Cells in Autoimmune Diseases: From Autoantibodies to Antigen Presentation
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 817 | Submission Open
Keywords: autoantibodies; B cells; antigen presentation; B cell functions; autoimmunity
(This special issue belongs to the Section Molecular Immunology)
Immunity in Neurodegenerative Diseases: Systemic Immune Imbalance, Neuroinflammation, and Beyond—2nd Edition
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 752 | Submission Open
Keywords: neurodegeneration; CNS immunosurveillance; neuroinflammation; neuroimmune axis; glia; T cells; phagocytosis; immunomodulation; autoimmunity; immunodeficiency
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Diagnostics and Therapeutic Targets in Bladder Cancer (Second Edition)
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 734 | Submission Open
Keywords: non-muscle invasive bladder cancer; muscle-invasive bladder cancer; metastatic bladder cancer; diagnostic biomarkers; therapeutic targets; early detection; progression biomarkers; liquid biopsy; genomic profiling; proteomics; metabolomics; imaging biomarkers; multi-omics; targeted therapy; immunotherapy; antibody– drug conjugates; DNA damage response; tumor microenvironment
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
New Insights into Network Pharmacology
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 677 | Submission Open
Keywords: network pharmacology; traditional medicine; drug discovery; computational biology; molecular mechanisms; protein– protein interaction; enrichment analysis; herb– compound– gene network
(This special issue belongs to the Section Molecular Pharmacology)
Advances in Molecular Biomarkers in Cancer and Metabolic Diseases submission deadline 28 Feb 2026 | 1 articles | Viewed by 675 | Submission Open
Keywords: biomarkers; cancer; metabolic disease; diagnosis; prognosis; treatment
(This special issue belongs to the Section Molecular Biology)
Marine Natural Products as a Source of Therapeutics—Recent Trends
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 593 | Submission Open
Keywords: marine natural products; marine-associated microbes; antimicrobial drug; antibiotics; marine-derived peptides; anti-inflammatory; molecular pharmacology; targeted therapies; extraction
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular and Cellular Biology of Germ Cells submission deadline 28 Feb 2026 | 1 articles | Viewed by 586 | Submission Open
Keywords: germ cell development; meiosis; epigenetic regulation; autophagy; mitochondrial dynamics; infertility; reproductive medicine; germ cell tumors; steroidogenesis; endocrine disrupting chemicals; reproductive toxicity
(This special issue belongs to the Section Molecular Biology)
Molecular Advances in Heart Disease: Genomics and Bioinformatics of Heart Research—2nd Edition
edited by Justyna Fert-Bober
submission deadline 28 Feb 2026 | 1 articles | Viewed by 443 | Submission Open
Keywords: heart disease; cardiovascular disease; coronary artery disease (CAD); heart attack; heart failure; arrhythmia (abnormal heart rhythms); valve disease; high blood pressure; congenital heart conditions; inherited heart conditions; fibrosis; pathobiology of fibrosis; aging; chronic inflammation; inflammatory and cardiovascular diseases; myocarditis; extracellular matrix biology
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Bridging Molecules and Reactions: Next-Generation Approaches for Advancing Electrocatalytic Efficiency submission deadline 28 Feb 2026 | 1 articles | Viewed by 412 | Submission Open
Keywords: electrochemical nanomaterials; energy storage and conversion; electrocatalysis and reaction mechanisms; photoelectrochemical water splitting; electrochemical energy storage devices; nanocomposites and functionalized materials; molecular-level electrocatalysis; electrocatalyst and photocatalysts; in-situ spectroscopy and atomistic modeling; hybrid molecular– nanostructured systems; sustainable and natural resource– derived materials; DFT related to reaction kinetics; AOP
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Advanced Functionalization of Biopolymers and Bio-Oligomers for Precision Therapeutics
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 390 | Submission Open
Keywords: precision therapeutics; biopolymers; drug delivery; biopharmaceuticals; pharmacology
(This special issue belongs to the Section Materials Science)
Role of Integrins in Cytokine Signaling
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 383 | Submission Open
Keywords: integrins; cytokines; FGF1; CX3CL1; ternary-complex; antagonist; inside-out signaling; integrin-binding motif; cytokine-integrin crosstalk; ligand-induced activation
(This special issue belongs to the Section Molecular Biology)
Metabolic Syndrome: New Insights in Pathogenesis, Diagnosis, Prevention, and Management—2nd Edition submission deadline 28 Feb 2026 | 1 articles | Viewed by 352 | Submission Open
Keywords: insulin resistance; hypertension; diabetes mellitus; obesity; inflammation; stress; metabolic disorders; reproductive endocrine disorders; polycystic ovarian syndrome; waist circumference; estrogen deficiency; disturbances in adipose tissue; physical inactivity; overnutrition; cardiovascular diseases; abdominal obesity; genetics and epigenetics of metabolic syndrome; computational analysis
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Pathophysiology and Molecular Mechanisms of Cardiovascular, Cardiometabolic, and Cardiorenal Diseases
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 349 | Submission Open
Keywords: heart failure; cardiorenal syndrome; oxidative stress; inflammation; endothelial dysfunction; fibrosis and remodeling; mitochondrial function and energy metabolism; insulin resistance; epigenetics and microRNAs; biomarkers and precision medicine
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Plant Protein and Enzyme Inhibitors
edited by Yan Zhang
submission deadline 28 Feb 2026 | Viewed by 346 | Submission Open
Keywords: plant proteins; active substances; bioactive compounds; enzyme inhibitors
(This special issue belongs to the Section Molecular Plant Sciences)
Schiff Bases and Their Metal Complexes: Structure, Synthesis, and Biological Application
edited by Nenad Filipovic
submission deadline 28 Feb 2026 | Viewed by 312 | Submission Open
Keywords: hydrazones; (thio/seleno)semicarbazones; oximes; antimicrobial activity; anticancer activity; enzyme inhibition; metal complexes; diagnostic agents; photothermal therapy; photodynamic therapy
(This special issue belongs to the Section Biochemistry)
Molecular Mechanisms of Toxicity Caused by Environmental Pollutants
edited by Ivan Girón-Perez
submission deadline 28 Feb 2026 | 1 articles | Viewed by 295 | Submission Open
Keywords: environmental pollutant; molecular toxicity; immunotoxicology; neurotoxicity
(This special issue belongs to the Section Molecular Toxicology)
Environmental Exposures and Chronic Obstructive Pulmonary Disease Pathogenesis submission deadline 28 Feb 2026 | Viewed by 254 | Submission Open
Keywords: chronic obstructive pulmonary disease; environmental exposures; disease pathogenesis
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
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