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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Insight into the Processing and Characterization of Animal Fats and Vegetable Oils

edited by

Pavel Mokrejš

submission deadline 20 Sep 2025 | 4 articles | Viewed by 9368 | Submission Open

Keywords: lipid molecules; oils; fats; lipase; interesterification; hydrolysis; phospholipids; fatty acids; molecular research; nutrition; cosmetics matrices; medical applications; food; pharmacy; bioengineering; novel applications; biofuels

(This special issue belongs to the Section Molecular Biology)

Current Advances and Perspectives in Microbial Genetics and Genomics

edited by

Marcello Tagliavia

and Lucila Saavedra

submission deadline 20 Sep 2025 | 6 articles | Viewed by 9262 | Submission Open

Keywords: microbial genetics; genomics and metagenomics; gene regulation; microbe– host interactions; adaption and resistance mechanisms; microbial metabolism

(This special issue belongs to the Section Molecular Microbiology)

Molecular Mechanisms and Pathophysiology of Sepsis

edited by

Vlad Pădureanu

submission deadline 20 Sep 2025 | 8 articles | Viewed by 9179 | Submission Open

Keywords: animal models; therapeutic concepts; biomarkers; sepsis; immune suppression; epigenetics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research in Spinal Cord Injury

edited by

Inbo Han

submission deadline 20 Sep 2025 | 4 articles | Viewed by 9098 | Submission Open

Keywords: spinal cord injury; molecular mechanisms; stem cell therapy; tissue engineering; neuroinflammation; neuroprotection; genetic regulation; epigenetics; therapeutic strategies

(This special issue belongs to the Section Molecular Neurobiology)

Molecular and Physiological Mechanisms of Exercise

edited by Zoran Nikolovski

submission deadline 20 Sep 2025 | 3 articles | Viewed by 9090 | Submission Open

Keywords: molecular biology; biochemistry and exercise; athletic performance; multi-omic

(This special issue belongs to the Section Molecular Biology)

Arrhythmias: Molecular Mechanisms and Therapeutic Strategies

edited by

Yung-Lung Chen

submission deadline 20 Sep 2025 | 4 articles | Viewed by 8853 | Submission Open

Keywords: cardiac arrhythmias; atrial fibrillation; ventricular arrhythmia; electrophysiologic alternation; ion channel; connexin; autonomic nerve system dysfunction; sleep-disordered breathing; obstructive sleep apnea

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms of Plant Abiotic Stress Tolerance: 2nd Edition

edited by

Michael Moustakas

submission deadline 20 Sep 2025 | 6 articles | Viewed by 8796 | Submission Open

Keywords: acclimation; drought; salinity; pesticides; high– low temperature; high– low light intensity; nutrient deficiencies; heavy metals; UV radiation; photosynthetic efficiency; ROS; antioxidant mechanisms; redox regulation

(This special issue belongs to the Section Molecular Plant Sciences)

Editorial Board Members’ Collection Series: Pain

edited by

Sebastiano Mercadante

and

István Nagy

submission deadline 20 Sep 2025 | 3 articles | Viewed by 8580 | Submission Open

Keywords: cancer; inflammation; neuropathy; primary sensory neurons; spinal cord; brain

(This special issue belongs to the Section Molecular Pharmacology)

Role of Natural Compounds in Human Health and Disease

edited by Jaewon Shim and

Wook-bin Lee

submission deadline 20 Sep 2025 | 6 articles | Viewed by 8549 | Submission Open

Keywords: natural compound; therapeutic applications; action mechanisms of natural compounds; traditional medicine

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Advances and Insights into Liver Diseases

edited by

Jacek Baj

submission deadline 20 Sep 2025 | 4 articles | Viewed by 8434 | Submission Open

Keywords: liver; hepatocellular carcinoma; cancer; hepatitis; cirrhosis; encephalopathy; non-alcoholic fatty liver disease; autoimmune diseases; Wilson’ s disease; fatty liver disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Zebrafish as a Model in Human Disease: 3rd Edition

edited by

Andrea Vettori

Nicola Facchinello

and

Marco G. Schiavone

submission deadline 20 Sep 2025 | 5 articles | Viewed by 8220 | Submission Open

Keywords: zebrafish; CRISPR/Cas9; transgenic lines; biosensors; endothelial cells; extracellular matrix; genetic mutant for human disease modeling; xenografts

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Boosting the Production of Bioactive Compounds: Biotechnology and Metabolic Engineering of Medicinal Plants

edited by

Katarzyna Hnatuszko-Konka

and

Izabela Grzegorczyk-Karolak

submission deadline 20 Sep 2025 | 5 articles | Viewed by 8144 | Submission Open

Keywords: bioactive compounds; plant tissue culture; elicitors; metabolic engineering; gene expression; medicinal plants; metabolic pathway; plant biotechnology

(This special issue belongs to the Section Molecular Plant Sciences)

Mycotoxins, Immunity, and Inflammation

edited by

Yuseok Moon

submission deadline 20 Sep 2025 | 5 articles | Viewed by 8133 | Submission Open

Keywords: mycotoxin; immunity; inflammation; immunotoxicity; immunology

(This special issue belongs to the Section Molecular Toxicology)

Viral Infections and Immune Responses

edited by

Alessandra Ruggiero

and

Marco Iannetta

submission deadline 20 Sep 2025 | 5 articles | Viewed by 8115 | Submission Open

Keywords: virus; infections; immune response; T-cells; B-cells; antibodies; neutralizing activity

(This special issue belongs to the Section Molecular Immunology)

Advanced Research of Metallic Nanoparticles

edited by

Edyta Proniewicz

submission deadline 20 Sep 2025 | 4 articles | Viewed by 8020 | Submission Open

Keywords: metallic nanoparticles (MNPs); biosensors; synthesis methods; molecular spectroscopy characteristic; molecular medicine; molecular biology

(This special issue belongs to the Section Molecular Nanoscience)

Molecular Research of Epithelial Function and Barrier Dysfunction

edited by Fariba Rezaee

submission deadline 20 Sep 2025 | 4 articles | Viewed by 7744 | Submission Open

Keywords: epithelial cells; actin cytoskeleton; viral infection; apical junctional complex; tight junction; adherens junction; barrier dysfunction; trans-epithelial electrical resistance; permeability; epithelial barrier

(This special issue belongs to the Section Molecular Immunology)

Molecular Biology of Protein Kinases: Regulatory Mechanisms, Therapeutic Targets and Cancer Treatments

edited by Jaw Ji Yang

submission deadline 20 Sep 2025 | 2 articles | Viewed by 7727 | Submission Open

Keywords: protein kinases; signal transduction; cancer therapy; regulatory mechanisms; kinase inhibitors; therapeutic targets; molecular biology; structural biology; translational research; clinical applications

(This special issue belongs to the Section Molecular Biology)

Redox Homeostasis and Oxidative Stress in Human Metabolism and Disease：2nd Edition

edited by

Alina Woźniak

and

Jaroslaw Nuszkiewicz

submission deadline 20 Sep 2025 | 7 articles | Viewed by 7562 | Submission Open

Keywords: antioxidants; biomarkers; cellular functions; disease etiology; disease progression; metabolic disorders; metabolic signaling; oxidative stress; pathophysiological states; reactive oxygen species; redox homeostasis; redox signaling

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Advances in Anti-Inflammatory Activity of Natural Products of Plant Origin

edited by Radoslaw Zajdel

submission deadline 20 Sep 2025 | 1 articles | Viewed by 7433 | Submission Open

Keywords: anti-inflammatory; phytochemicals; natural products; medicinal plants; inflammation; cytokines; NF-κ B pathway; cyclooxygenase inhibitors; flavonoids; terpenoids; polyphenols; molecular mechanisms; drug discovery; ethnopharmacology; metabolomics

(This special issue belongs to the Section Bioactives and Nutraceuticals)

The Role and Mechanism of P2X7 Receptor in Cancer and Inflammatory Diseases

edited by

Anna Lisa Giuliani

submission deadline 20 Sep 2025 | 3 articles | Viewed by 7401 | Submission Open

Keywords: P2X7 receptor; inflammation; cancer; purinergic signalling

(This special issue belongs to the Section Molecular Immunology)

Drug Discovery: Design, Synthesis and Activity Evaluation

edited by

Joana L. C. Sousa

and

Artur M. S. Silva

submission deadline 20 Sep 2025 | 4 articles | Viewed by 7328 | Submission Open

Keywords: drug design; organic synthesis; biological activity evaluation; biologically active compounds; diagnostic/therapeutic agents; labeled ligands; structure– activity relationships (SARs); structural biological studies; computational studies; pharmacokinetics/pharmacodynamics; drug delivery

(This special issue belongs to the Section Molecular Pharmacology)

Advances in Melanoma and Skin Cancers: 2nd Edition

edited by

Domenico Mallardo

Debora Basile

and Maria Grazia Vitale

submission deadline 20 Sep 2025 | 6 articles | Viewed by 7317 | Submission Open

Keywords: melanoma; immunotherapy; biomarkers; translational research; drug repurposing; clinical outcome; prognostic markers; predictive markers; combination immunotherapy

(This special issue belongs to the Section Molecular Oncology)

Molecular Basis of Pancreatic Secretion and Metabolism

edited by

Dongki Yang

submission deadline 20 Sep 2025 | 5 articles | Viewed by 7288 | Submission Open

Keywords: exocrine of the pancreas; endocrine of the pancreas; acute pancreatitis; chronic pancreatitis; cystic fibrosis; pancreatic metabolic hormones; pancreatic metabolic disease; mechanism of pancreatic bicarbonate secretion; the sodium bicarbonate cotransporter (NBC); cystic fibrosis transmembrane conductance regulator (CFTR); regulators of the ion channels and ion transporters involved in secretion

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Flow Cytometry: Applications and Challenges

edited by

Alessandra Falda

submission deadline 20 Sep 2025 | 5 articles | Viewed by 7282 | Submission Open

Keywords: flow cytometry; non-conventional flow cytometry; hematology; morphology; molecular tests; cell biology; immunology; target therapy; microbiology; antigens; functional mechanisms; new technologies

(This special issue belongs to the Section Molecular Biology)

The Biochemistry, Molecular and Cell Biology Beyond Flowers

edited by

Isabel Marques

submission deadline 20 Sep 2025 | 3 articles | Viewed by 7240 | Submission Open

Keywords: flowers; homeotic genes; MADSBox; molecular expression; pollination; stress; transcription factors

(This special issue belongs to the Section Molecular Plant Sciences)

Oxidative Stress and Cell Damage

edited by Haruhiko Inufusa, Koji Abe and Shigeru Hirano

submission deadline 20 Sep 2025 | 2 articles | Viewed by 7193 | Submission Open

Keywords: oxidative stress; damages on cells; organs; body; prevention damages; parameter of oxidative stress; antioxidants

(This special issue belongs to the Section Molecular Biology)

Molecular Mechanisms of Microbe–Skin Interactions

edited by

Friedrich Götz

submission deadline 20 Sep 2025 | 4 articles | Viewed by 7173 | Submission Open

Keywords: colonization; cosmetics; diseases (e.g.; acne; diabetic foot syndrome (DFS); psoriasis; etc.); health; immunity; lipidomics; metabolomics; metagenomics; neurotransmitter; physiology; skin habitat; skin microbiota; prebiotics; probiotics; wound healing

(This special issue belongs to the Section Molecular Microbiology)

State-of-the-Art Molecular Immunology in Chile, 2nd Edition

edited by

Marcela Hernandez Ríos

Juan C. Aguillon

, María Rosa Bono,

Nicolas Dutzan

Rolando Vernal

and

Leandro J. Carreño

submission deadline 20 Sep 2025 | 3 articles | Viewed by 7079 | Submission Open

Keywords: innate immunity; adaptive immunity; host– pathogen interactions; immunopathology; osteoimmunology; immunosenescence; immunotherapy; antibody; vaccines; Chile

(This special issue belongs to the Section Molecular Immunology)

Bioactive Compounds and Their Anticancer Effects

edited by

Ji Hoon Jung

submission deadline 20 Sep 2025 | 5 articles | Viewed by 7055 | Submission Open

Keywords: ferroptosis; natural compounds; bioactive compounds; p53; anti-cancer drugs

(This special issue belongs to the Section Bioactives and Nutraceuticals)

CNS Injuries: 2nd Edition

edited by

Sudhanshu Raikwar

submission deadline 20 Sep 2025 | 1 articles | Viewed by 6978 | Submission Open

Keywords: stroke; TBI; brain edema; SCI; spinal cord edema; neuroinflammation; neurodegeneration

(This special issue belongs to the Section Molecular Neurobiology)

Application of Natural Products in Biomedicine and Pharmacotherapy: 2nd Edition

edited by

George Miloshev

submission deadline 20 Sep 2025 | 6 articles | Viewed by 6901 | Submission Open

Keywords: natural products; biomedicine; genotoxicity; epigenetics; aging

(This special issue belongs to the Section Molecular Pharmacology)

New Insights into Anti-cancer Drug Discovery and Development

edited by

Ki-cheong Park

submission deadline 20 Sep 2025 | 3 articles | Viewed by 6870 | Submission Open

Keywords: anti-cancer drug resistant; cancer recurrence; cancer metastasis; cancer stem cells; target validation; target identification; metabolic reprogramming of cancer stem cells; unmet medical needs

(This special issue belongs to the Section Molecular Pharmacology)

Advances in Research for Legume Genomics, Genetics, and Breeding, 2nd Edition

edited by

Naoufal Lakhssassi

submission deadline 20 Sep 2025 | 4 articles | Viewed by 6712 | Submission Open

Keywords: legumes; genomics; plant breeding; seed composition; gene function; biotic and abiotic stress; legume pathogen resistance/mechanisms

(This special issue belongs to the Section Molecular Plant Sciences)

Editorial Board Members’ Collection Series: Autoimmune Diseases—2nd Edition

edited by

Yves Renaudineau

and

Dirk Roggenbuck

submission deadline 20 Sep 2025 | 5 articles | Viewed by 6458 | Submission Open

Keywords: autoimmunity; autoimmune diseases; immunotherapy; biomarkers; pathogenic mechanisms

(This special issue belongs to the Section Molecular Immunology)

Natural Compounds for Counteracting GI and Liver Diseases

edited by

Daniela Gabbia

and

Raquel Abalo

submission deadline 20 Sep 2025 | 4 articles | Viewed by 6433 | Submission Open

Keywords: natural compounds; gastrointestinal diseases; liver diseases; pharmacological potential

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Mechanisms and Therapies for Metabolic-Associated Fatty Liver Diseases

edited by Yi-Ming Arthur Chen

submission deadline 20 Sep 2025 | 2 articles | Viewed by 6430 | Submission Open

Keywords: metabolic-associated fatty liver disease; MAFLD; metabolic dysfunction-associated steatohepatitis; MASH; molecular mechanism; genetic polymorphism; individualized medicine; prevention; new drug development; health supplements; diagnosis; epidemiology; lifestyle

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Apoptosis and Autophagy as Strategies in Cancer Treatment

edited by Dorota Ciołczyk-Wierzbicka

submission deadline 20 Sep 2025 | 3 articles | Viewed by 6261 | Submission Open

Keywords: apoptosis; autophagy; cancer therapy/treatment; drug resistance; signaling pathways

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Advances in Stem Cells in Human Health and Diseases

edited by

Elisaveta N. Voynova

submission deadline 20 Sep 2025 | 5 articles | Viewed by 6187 | Submission Open

Keywords: stem cells biology; iPSCs; hESC

(This special issue belongs to the Section Molecular Biology)

Noncovalent Interactions and Applications in Materials and Catalysis

edited by Snežana D. Zarić

submission deadline 20 Sep 2025 | 4 articles | Viewed by 5945 | Submission Open

Keywords: noncovalent interactions; materials; catalysis; crystal structures; quantum chemistry calculations; hydrogen bonds; stacking interactions; spectroscopy

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

The Role of Oxidative Stress and Antioxidants in Human Disease

edited by

Federica Mannino

submission deadline 20 Sep 2025 | 4 articles | Viewed by 5869 | Submission Open

Keywords: oxidative stress; free radicals; antioxidants; reactive oxygen species (ROS); polyphenols

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Exploring the Pathogenetic Mechanisms in Respiratory Virus Infections: Recent Advances and Future Directions

edited by

Marta De Angelis

submission deadline 20 Sep 2025 | 3 articles | Viewed by 5861 | Submission Open

Keywords: respiratory viruses; virus-host interactions; inflammation; metabolic pathways

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Neurodegenerative Diseases and Inflammation: Pathogenesis, Biomarkers and Treatments

edited by

Luisa Agnello

and Anna Maria Ciaccio

submission deadline 20 Sep 2025 | 2 articles | Viewed by 5820 | Submission Open

Keywords: neurodegeneration; inflammation; biomarkers; Alzheimer’ s disease; molecular mechanism; pathogenesis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances in Cell Proliferation, Senescence and Apoptosis

edited by

Chuanxi Cai

submission deadline 20 Sep 2025 | 3 articles | Viewed by 5699 | Submission Open

Keywords: biological molecules; cell proliferation; senescence; apoptosis; human diseases

(This special issue belongs to the Section Molecular Biology)

Emerging Advances in Cancer Biomarkers: Machine Learning, Radiomics, Genomics, and More

edited by

Hung-Yu Lin

and

Pei-Yi Chu

submission deadline 20 Sep 2025 | 3 articles | Viewed by 5681 | Submission Open

Keywords: cancers; biomarkers; precision medicine; artificial intelligence; machine learning; radiomics; genomics; radiogenomics; multi-omics; pharmacogenetics

(This special issue belongs to the Section Molecular Genetics and Genomics)

Musculoskeletal Disorders: From Molecular Pathology to Novel Therapeutic Approach

edited by

María Orosia Lucha López

submission deadline 20 Sep 2025 | 4 articles | Viewed by 5589 | Submission Open

Keywords: joints; skeletal muscles; tendons; ligaments; fascia; articular cartilage; intervertebral discs; physiotherapy; novel therapies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Biofunctional Coatings for Medical Applications

edited by

Liviu Duta

Valentina Grumezescu

and

Gabriela Dorcioman

submission deadline 20 Sep 2025 | 4 articles | Viewed by 5507 | Submission Open

Keywords: biofunctional coatings; thin film deposition techniques; surface engineering; tissue engineering; materials’ doping and co-doping; medical applications

(This special issue belongs to the Section Materials Science)

Fish Immunology, 5th Edition

edited by

Alberto Cuesta

and

Elena Chaves-Pozo

submission deadline 20 Sep 2025 | 4 articles | Viewed by 5407 | Submission Open

Keywords: fish immunology; innate immunity; acquired immunity; leucocytes; disease; immunostimulants; immunodepression; inflammation

(This special issue belongs to the Section Molecular Immunology)

Application of Genetic Engineering in Treatments for Human Diseases

edited by Claudio Mussolino

submission deadline 20 Sep 2025 | 2 articles | Viewed by 5396 | Submission Open

Keywords: genome editing; epigenome editing; CRISPR-Cas systems; gene therapy; precision medicine; molecular mechanisms; innovative therapies; gene expression regulation

(This special issue belongs to the Section Molecular Genetics and Genomics)

New Insights in Prion Diseases

edited by

Eva Bagyinszky

submission deadline 20 Sep 2025 | 1 articles | Viewed by 5348 | Submission Open

Keywords: prion diseases; prion mutation; genetic modifier; neurodegenerative diseases; therapy; neuroprotection

(This special issue belongs to the Section Molecular Neurobiology)

Advanced Synthetic Methodologies in Drug Development

edited by

Davide Moi

submission deadline 20 Sep 2025 | 3 articles | Viewed by 5293 | Submission Open

Keywords: organic chemistry; medicinal chemistry; catalysis; photo-catalysis; green chemistry; drug design; drug analysis; flow chemistry

(This special issue belongs to the Section Molecular Pharmacology)

Displaying special issue 551-600 on page 12 of 68.

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