Antioxidants and Redox Biomarkers: Beneficial and Harmful Effects on Human Health

Dear Colleagues,

Redox homeostasis is a fundamental determinant of human health, and antioxidants play a pivotal role in modulating oxidative balance and cellular signaling pathways. While antioxidants are traditionally associated with protective effects, increasing evidence suggests that their biological impact is highly context-dependent, with potential harmful consequences related to dose, exposure, and redox environment. A deeper understanding of these dual effects requires integrated molecular approaches and reliable redox-related indicators. This Special Issue aims to collect original research articles and reviews addressing the beneficial and harmful effects of antioxidants on human health, in line with the scope of the International Journal of Molecular Sciences. Contributions exploring redox homeostasis, oxidative stress pathways, and related biomarkers in experimental and clinical settings are encouraged.

Suggested topics include endogenous and dietary antioxidants, redox signaling and adaptation, methodological approaches for assessing redox status, and emerging biomarkers of antioxidant activity and redox imbalance. 

I look forward to receiving your contributions.

Dr. Ramona D'Amico
Guest Editor

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