Functional Precision Medicine in Rare Cancers: Organoid Models and Integrated Omics Profiling
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 31 August 2026 | Viewed by 31
Special Issue Editors
2. Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55902, USA
Interests: cancer research; organoids; functional precision medicine; new approach methodologies; genomics; transcriptomics; epigenomics; multiomics
Special Issue Information
Dear Colleagues,
The field of organoid research has experienced explosive growth and continues to expand, supported by recommendations from regulatory and advisory bodies advocating the adoption of new approach methodologies (NAMs). In parallel, ‘omics approaches have become ubiquitous in biomedical research over recent decades, with a continually expanding range of methodologies and applications. Oncology, in particular, has benefited substantially from advances in both organoid and ‘omics technologies: organoids are increasingly demonstrating clinical correlation, while ‘omics approaches enable patient stratification and the discovery of novel biomarkers, ultimately supporting more precise and targeted treatments.
The convergence of these two powerful fields holds significant potential to revolutionize oncology research and treatment paradigms, particularly in rare cancers that frequently receive less attention and research funding than common malignancies.
Through this Special Issue, entitled “Functional Precision Medicine in Rare Cancers: Organoid Models and Integrated Omics Profiling”, we aim to bring together key contemporary research incorporating organoid models and ‘omics technologies in the context of rare cancers, fostering scientific dialogue and the next frontier of oncology research.
Dr. Gavin Robert Oliver
Dr. Carlton C Barnett
Guest Editors
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Keywords
- organoids
- rare cancer
- new approach methodologies
- oncology
- precision medicine
- functional precision medicine
- multiomics
- genomics
- transcriptomics
- epigenomics
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