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Molecular Mechanisms in Cardiovascular and Metabolic Diseases: Effective and Potential Treatments

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".

Deadline for manuscript submissions: 31 August 2026 | Viewed by 14

Special Issue Editor


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Guest Editor
Laboratory of Biochemistry and Molecular Biology of the Exercise, Physical Education and Sport School, University of São Paulo, São Paulo 05508-030, Brazil
Interests: molecular mechanisms; cancer; cardiovascular diseases; metabolic diseases; treatments
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Cardiovascular diseases are the leading causes of death worldwide. In recent years, several studies have demonstrated various dysregulated cellular and molecular mechanisms that favor pathophysiological processes such as inflammation, increased reactive oxygen species, apoptosis, and fibrosis, inducing the development and progression of these diseases. Many of these molecular mechanisms are regulated by non-coding RNAs, such as microRNAs, circRNAs, and long non-coding RNAs. Understanding these mechanisms will enable the creation of new treatments, and these molecules can also serve as new biomarkers for diagnosis and targeted gene therapy. Accordingly, this Special Issue focuses on articles that highlight microRNAs, circRNAs, and long non-coding RNAs as potential biomarkers of cardiovascular and metabolic diseases, elucidate new dysregulated signaling pathways involved in these conditions, and evaluate responses to treatment interventions. We welcome submissions of original preclinical and clinical articles, reviews, mini-reviews, and letters.

I look forward to receiving your contributions.

Dr. Alex Cleber Improta-Caria
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • molecular mechanisms
  • cardiovascular diseases
  • metabolic diseases
  • microRNAs
  • circRNAs
  • long non-coding RNAs
  • epigenetics

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Published Papers

This special issue is now open for submission.
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