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  • Article
  • Open Access
383 Views
10 Pages

20 November 2025

Background/Objectives: Thyroid dysfunction during pregnancy is associated with a range of adverse perinatal outcomes. This study aims to evaluate the effect of maternal thyroid autoimmunity on selected gestational and perinatal outcomes of the newbor...

  • Review
  • Open Access
334 Views
11 Pages

Diagnosis of Congenital and Acquired Generalized Lipodystrophies—Similarities and Differences

  • Josivan Gomes Lima,
  • Lucas Nobrega Lima,
  • Vitor Yan Bezerra Araujo,
  • Lucia Helena Coelho Nobrega and
  • Julliane Tamara Araújo de Melo Campos

17 November 2025

Generalized lipodystrophies (GLs) are rare diseases characterized by a lack of body fat. When patients with a GL phenotype are referred with a presumptive diagnosis of congenital generalized lipodystrophy (CGL) but genetic testing for known pathogeni...

  • Review
  • Open Access
1 Citations
991 Views
13 Pages

For many years, menopause-related bone loss has been attributed solely to declining estrogen levels. Recently it has been suggested that bone loss accelerates during perimenopause, often preceding declines in estradiol (E2), proposing that follicle-s...

  • Feature Paper
  • Review
  • Open Access
907 Views
11 Pages

The ovarian corpus luteum has functional mechanisms for formation and regression in the reproductive endocrine system. The main functional events of the corpus luteum are angiogenesis and apoptosis mechanisms. The development of the corpus luteum inv...

  • Article
  • Open Access
1,321 Views
18 Pages

Gestational Weight Gain and Adverse Pregnancy Outcomes in Women with Gestational Diabetes Mellitus and Obesity

  • Filipe Dias de Souza,
  • Patrícia Medici Dualib,
  • Martha Camillo Jordão,
  • Micaela Frasson Montero,
  • Maria Carolina Oliveira Abate,
  • Leonardo Luna,
  • Rosiane Mattar and
  • Bianca de Almeida-Pititto

Background/Objectives: The association between gestational weight gain (GWG) and adverse outcomes in individuals with gestational diabetes mellitus (GDM) and obesity remains unclear. This study aimed to evaluate the relationship between total GWG and...

  • Article
  • Open Access
581 Views
18 Pages

Circulating miR-122 and miR-139-3p: Association with Lipid, Inflammatory, and Glycemic Profile in Adolescents with Insulin-Resistant and Overweight

  • Tanyara Baliani Payolla,
  • Paula Nascimento Brandão-Lima,
  • Gabrielli Barbosa de Carvalho,
  • Flávia Mori Sarti,
  • Regina Mara Fisberg and
  • Marcelo Macedo Rogero

Background/Objectives: Insulin resistance (IR) in adolescents contributes to the development of metabolic and immunological alterations. These alterations can lead to chronic, systemic, low-grade inflammation in adulthood. Evidence suggests that alte...

  • Article
  • Open Access
742 Views
10 Pages

Obesity Is Associated with Larger Thyroid Nodules but Not with Malignant Cytology

  • Stefania Giuliano,
  • Giuseppe Seminara,
  • Stefano Iuliano,
  • Stefania Obiso,
  • Eusebio Chiefari,
  • Daniela P. Foti,
  • Maria Mirabelli and
  • Antonio Brunetti

Background: Obesity has been proposed as a risk factor for differentiated thyroid carcinoma (DTC), though findings in the literature remain conflicting. While some studies suggest an association between elevated body mass index (BMI) and thyroid mali...

  • Review
  • Open Access
1 Citations
6,114 Views
27 Pages

Sleep Deprivation and Its Impact on Insulin Resistance

  • Margarida C. Pinheiro,
  • Henrique E. Costa,
  • Melissa Mariana and
  • Elisa Cairrao

Background/Objectives: Adequate sleep has a fundamental role in human health, mainly in cognitive and physiological functions. However, the daily demands of modern society have led to a constant pursuit of better living conditions, requiring more act...

  • Review
  • Open Access
1 Citations
4,601 Views
22 Pages

Comparing Glucometer-Based and Laboratory-Based OGTT for Diabetes Diagnosis: A Narrative Review

  • Tanvir Ahmed,
  • Jaimala Kishore,
  • Mensila Onamika,
  • Shuvratithi Goswami,
  • Iffat Rahman Momo,
  • Hanif Sumon and
  • Rodney G. Bowden

18 September 2025

Background: The oral glucose tolerance test (OGTT) is the gold standard for diagnosing diabetes; however, its use is often limited by the need for laboratory infrastructure, trained personnel, and extended turnaround times. In contrast, glucometer-ba...

  • Review
  • Open Access
2,358 Views
12 Pages

18 September 2025

The intersection of type 2 diabetes mellitus (T2DM) and sarcopenia, often termed diabetic sarcopenia, represents a critical yet underrecognized comorbidity that significantly impacts the quality of life and functional capacity of older adults. This p...

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Endocrines - ISSN 2673-396X