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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in the Diagnosis and Management of Morbid Obesity

edited by Justyna Domienik-Karłowicz

submission deadline 31 Jul 2026 | 1 articles | Viewed by 872 | Submission Open

Keywords: morbid obesity; obesity diagnosis; body composition analysis; visceral adiposity; metabolic syndrome; biomarkers in obesity; genetic predisposition; comorbidity assessment; imaging techniques; risk stratification

(This special issue belongs to the Section Medical Imaging and Theranostics)

Emerging Technologies in Breast Imaging

edited by

Yufeng Zhou

submission deadline 31 Jul 2026 | 1 articles | Viewed by 810 | Submission Open

Keywords: ultrafast ultrasound; photon-counting CT; abbreviated MRI; optoacoustic tomography; contrast-enhanced mammography; PEM; breast PET/MRI; radiomics; deep-learning reconstruction; cone-beam CT

(This special issue belongs to the Section Medical Imaging and Theranostics)

New Insights into Molecular Diagnostic Technologies

edited by Hin Fung Tsang

submission deadline 31 Jul 2026 | Viewed by 791 | Submission Open

Keywords: molecular diagnostics; advanced technologies; disease diagnosis; disease monitoring; disease management; personalized medicine

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in the Diagnosis of Surgical Pathology

edited by Dong Ren

submission deadline 31 Jul 2026 | Viewed by 604 | Submission Open

Keywords: pathological diagnosis; diagnostic dilemma and pitfall; molecular pathology; digital pathology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Artificial Intelligence in the Service of Medicine: From Pathological Diagnosis to Forensic Pathology

edited by

Gelsomina Mansueto

submission deadline 31 Jul 2026 | 1 articles | Viewed by 583 | Submission Open

Keywords: artificial intelligence in pathology; digital pathology; computational pathology; whole-slide imaging (WSI); machine learning-based diagnostics; deep learning algorithms; pathology; cardiopathology; neuropathology; forensic pathology; postmortem imaging analysis; biomarker detection and quantification

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Diagnostic Markers of Genitourinary Tumors: 2nd Edition

edited by

Francesca Sanguedolce

and

Roberta Mazzucchelli

submission deadline 31 Jul 2026 | Viewed by 582 | Submission Open

Keywords: genitourinary tumors; diagnostic markers; biomarkers; molecular diagnostics; personalized medicine

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Images in the Diagnosis of Macular Edema, Second Edition

edited by

Gawęcki Maciej

submission deadline 31 Jul 2026 | 1 articles | Viewed by 573 | Submission Open

Keywords: macular edema; diagnostic imaging; optical coherence tomography (OCT); fluorescein angiography; retinal imaging techniques

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Diagnostic and Interventional Nephrology

edited by Ammar Almehmi

submission deadline 31 Jul 2026 | Viewed by 562 | Submission Open

Keywords: dialysis access; fistula; graft; stent; peritoneal catheter; drug-coated balloon; EndoAVF; dialysis; vascular access dysfunction; interventional nephrology; diagnostic imaging

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Image Guided Neurointerventional Surgery: Focus on Diagnosis and Outcomes

edited by Dheeraj Gandhi and Huanwen Chen

submission deadline 31 Jul 2026 | Viewed by 369 | Submission Open

Keywords: image guided neurointerventional surgery; diagnosis; outcomes; computed tomography (CT); magnetic resonance imaging (MRI)

(This special issue belongs to the Section Medical Imaging and Theranostics)

Application of Artificial Intelligence in Gastrointestinal Disease, 2nd Edition

edited by

Kai Zhao

submission deadline 31 Jul 2026 | Viewed by 337 | Submission Open

Keywords: artificial intelligence; machine learning; gastrointestinal disease

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Pediatric Gastrointestinal Pathology—2nd Edition

edited by Juan Putra

submission deadline 31 Jul 2026 | Viewed by 331 | Submission Open

Keywords: inflammatory bowel disease; Crohn’s disease; celiac disease; ulcerative colitis; vascular anomalies; eosinophilic esophagitis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Diagnosis and Management of Hepatitis

edited by

Qi Wang

submission deadline 31 Jul 2026 | Viewed by 331 | Submission Open

Keywords: viral hepatitis; hepatitis B virus hepatitis; drug-induced liver injury; autoimmune hepatitis; metabolic-associated fatty liver disease; alcoholic liver disease; diagnosis; follow-up management

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Advances and Future of Blood Specimen Collection, Testing and Analysis

edited by

Greg J. Sommer

submission deadline 31 Jul 2026 | Viewed by 309 | Submission Open

Keywords: blood testing; sample collection; point-of-care testing; pre-analytics; laboratory automation; continuous monitoring; patient-centric sampling; at-home diagnostics

(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)

Advances in Tumor Cytopathology: Diagnostic Innovations and Applications

edited by Joshua Jing Xi Li and Swati Satturwar

submission deadline 31 Jul 2026 | Viewed by 298 | Submission Open

Keywords: cytopathology; digital pathology; tumor; molecular pathology; diagnosis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Innovations in Minimally Invasive Urology: Robotics for Reconstruction, Male Health and Diagnostics

edited by

Lucio Dell'Atti

submission deadline 31 Jul 2026 | Viewed by 252 | Submission Open

Keywords: robotic surgery; urology; reconstructive surgery; male health; technological development; diagnostic technology; minimally invasive diagnosis; image-guided procedures; biopsy techniques; diagnostic imaging; disease classification; patient stratification; diagnostic protocols; diagnostic accuracy; surgical diagnosis; pathological evaluation; precision diagnosis; diagnostic innovation

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostic Challenges in Complex and Severe Allergic Conditions

edited by Yuxiang Zhi

submission deadline 31 Jul 2026 | Viewed by 204 | Submission Open

Keywords: diagnostic challenges; severe allergic condition; biomarkers; immunologic testing; cellular mechanisms

Pathological and Clinical Features of Non-Small Cell Lung Cancer

edited by

Luigi Ventura

submission deadline 31 Jul 2026 | Viewed by 192 | Submission Open

Keywords: non-small cell lung cancer; NSCLC; thoracic oncology; radiology; EBUS; navigational bronchoscopy; lung pathology; molecular biomarkers; STAS; immunotherapy; segmentectomy; lobectomy; perioperative therapy

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Grand Challenges in the Diagnosis and Management of Cardiovascular and Cerebrovascular Diseases, 2nd Edition

edited by

Sonu M. M. Bhaskar

submission deadline 1 Aug 2026 | Viewed by 297 | Submission Open

Keywords: cardiovascular diseases; cerebrovascular diseases; stroke; diagnosis; management; imaging; biomarkers; artificial intelligence; therapeutic strategies; surgery; rehabilitation; multidisciplinary

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

From Clinical Diagnosis to Effective Treatment of Cardiomyopathy

edited by

Sanjay Sivalokanathan

and

Łukasz A. Małek

submission deadline 20 Aug 2026 | Viewed by 262 | Submission Open

Keywords: hypertrophic cardiomyopathy; dilated cardiomyopathy; non-ischemic cardiomyopathy; cardiac MRI; PET/CT; PET/MRI; cardiac imaging; sudden cardiac death

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Clinical Applications of PET/CT: Current Status and Future Perspectives

edited by Emmanouil Panagiotidis and

Jules T. Zhang-Yin

submission deadline 30 Aug 2026 | 1 articles | Viewed by 2904 | Submission Open

Keywords: PET/CT; diagnostic imaging; molecular imaging; oncology; PSMA; FAPI; SSTR; novel tracers; quantitative PET

(This special issue belongs to the Section Medical Imaging and Theranostics)

New Advances in Cerebrovascular Disease: Clinical Diagnosis, Treatment, and Prognosis

edited by Federico Mazzacane

submission deadline 30 Aug 2026 | Viewed by 2347 | Submission Open

Keywords: cerebrovascular disease; ischemic stroke; intracerebral hemorrhage; neuroimaging; prognosis; biomarkers; precision medicine; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Integrating Health Informatics and Artificial Intelligence for Advanced Medicine

edited by

Joaquim Carreras

submission deadline 30 Aug 2026 | Viewed by 650 | Submission Open

Keywords: artificial intelligence; machine learning; artificial neural networks; prognosis; treatment; medicine; health care; pathology

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Brain/Neuroimaging 2025–2026

edited by Ronald Antulov

submission deadline 31 Aug 2026 | 14 articles | Viewed by 27433 | Submission Open

Keywords: advanced neuroimaging; dual-energy CT; photon-counting CT; perfusion MRI; MRI fingerprinting; brain lesions; neurodegenerative disorders; brain imaging; diagnosis; prognosis

(This special issue belongs to the Section Medical Imaging and Theranostics)

Vascular Diagnostic Imaging

edited by

Hyo-Suk Ahn

submission deadline 31 Aug 2026 | 5 articles | Viewed by 25492 | Submission Open

Keywords: flow-mediated dilation (FMD); optical coherence tomography (OCT); intravascular ultrasound (IVUS)

(This special issue belongs to the Section Medical Imaging and Theranostics)

Game-Changing Concepts in Reproductive Health

edited by Mark I. Evans and Christian R. Macedonia

submission deadline 31 Aug 2026 | 8 articles | Viewed by 16940 | Submission Open

Keywords: pregnancy; artificial intelligence; prenatal diagnosis; genetic sequencing; diagnostic tests; screening tests; public policy; electronic fetal monitoring; introducing new technologies

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Dental Diagnostics

edited by

Dirk Ziebolz

and Margherita Fontana

submission deadline 31 Aug 2026 | 11 articles | Viewed by 16552 | Submission Open

Keywords: diagnosis; diagnostic imaging; artificial intelligence; caries; periodontitis; stomatognathic diseases

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosing Respiratory Diseases and Impaired Gas Exchange Using Machine Learning

edited by

Robert LeMoyne

Jakub Rafl

and Martin Rozanek

submission deadline 31 Aug 2026 | 4 articles | Viewed by 14302 | Submission Open

Keywords: machine learning; user trust with machine learning; deep learning; blood gas sensors; oximeters; wearables; computer automated diagnosis of health status; respiratory diseases; impaired gas exchange; advanced diagnostics

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Recent Developments and Future Trends in Thoracic Imaging

edited by Ioana Andreea Gheonea

submission deadline 31 Aug 2026 | 8 articles | Viewed by 13277 | Submission Open

Keywords: X-ray; computed tomography; magnetic resonance imaging; ultra-low-dose CT; photon-counting CT; oncology; artificial intelligence; emergency radiology; thoracic trauma

(This special issue belongs to the Section Medical Imaging and Theranostics)

Artificial Intelligence in Dermatology

edited by Choon Chiat Oh

submission deadline 31 Aug 2026 | 6 articles | Viewed by 13097 | Submission Open

Keywords: dermatology; artificial intelligence; deep learning; skin cancers; diagnostic imaging

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

New Insights into the Diagnosis and Prognosis of Eye Diseases

edited by

Rosa Giglio

and

Daniele Tognetto

submission deadline 31 Aug 2026 | 8 articles | Viewed by 12184 | Submission Open

Keywords: diagnosis; prognosis; eye diseases; markers; clinical practice and patient care

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Dermatology and Venereology: Diagnosis and Management

edited by

Giulia Ciccarese

submission deadline 31 Aug 2026 | 4 articles | Viewed by 10582 | Submission Open

Keywords: skin infections; sexually transmitted infections; human papillomavirus; syphilis; pityriasis rosea; exanthem

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Metabolic Diseases: Diagnosis, Management, and Pathogenesis

edited by Dee Pei

submission deadline 31 Aug 2026 | 5 articles | Viewed by 9744 | Submission Open

Keywords: metabolic disease; obesity; aging; machine learning; pathophysiology; prevalence; ethnic differences

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Application of Artificial Intelligence to Oral Diseases

edited by

Gang Li

submission deadline 31 Aug 2026 | 6 articles | Viewed by 9518 | Submission Open

Keywords: oral disease; artificial intelligence; AI-driven diagnosis; oral radiology; cone beam computed tomography (CBCT)

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

AI and Digital Health for Disease Diagnosis and Monitoring, 2nd Edition

edited by AKM Azad, Mohammad Ali Moni and

Hussain Mohammed Dipu Kabir

submission deadline 31 Aug 2026 | 8 articles | Viewed by 9175 | Submission Open

Keywords: artificial intelligence; chronic disease; disease monitoring; disease prediction; machine learning; personalized treatment; health technology; big data analytics; public health; wearable health devices

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Current Perspectives and Gaps in the Diagnosis and Management of Rheumatic Diseases

edited by Vikas Majithia

submission deadline 31 Aug 2026 | 4 articles | Viewed by 8179 | Submission Open

Keywords: rheumatology; rheumatic diseases; inflammatory connective tissue diseases; rheumatoid arthritis; systemic lupus erythematosus; vasculitis; spondyloarthritis; scleroderma; osteoarthritis; current perspective; diagnosis; treatment; management

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Pathophysiologic Mechanisms, Diagnosis and Management of Venous Thromboembolism

edited by Emanuele Valeriani

submission deadline 31 Aug 2026 | 5 articles | Viewed by 7313 | Submission Open

Keywords: anticoagulants; deep vein thrombosis; diagnosis; pathophysiology; pulmonary embolism; venous thrombosis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnostics and Therapeutic Explorations in Aging

edited by

Alvita Vilkevičiūtė

submission deadline 31 Aug 2026 | 3 articles | Viewed by 6756 | Submission Open

Keywords: molecular markers; genetics; epigenetics; biochemistry; biomarkers; telomeres; age-related disease; senescence; mitochondrial dysfunction; immunogenetics

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in Clinical Biochemistry, 2nd Edition

edited by Yu Chen

submission deadline 31 Aug 2026 | 3 articles | Viewed by 6312 | Submission Open

Keywords: clinical biochemistry; medical diagnosis; biomarkers; proteomic profiling; metabolomic profiling; high throughput technologies

(This special issue belongs to the Section Clinical Laboratory Medicine)

New Advances in Thoracic Surgery: Clinical Diagnosis, Treatment, and Prognosis—2nd Edition

edited by

Stefano Elia

submission deadline 31 Aug 2026 | 4 articles | Viewed by 5805 | Submission Open

Keywords: thoracic surgery; lung cancer; pleural diseases; mediastinal malignancies; surgical outcome

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Head and Neck and Oral Maxillofacial Radiology

edited by

Qiyong Hemis Ai

submission deadline 31 Aug 2026 | 4 articles | Viewed by 5559 | Submission Open

Keywords: medical imaging; head and neck; machine learning; radiomics analysis; medical image analysis

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Management in Cardiac Intensive Care Medicine

edited by

Elad Asher

submission deadline 31 Aug 2026 | 3 articles | Viewed by 5408 | Submission Open

Keywords: cardiac intensive care; cardiogenic shock; acute heart failure; hemodynamic monitoring; mechanical circulatory support; post-cardiac arrest care; critical care cardiology

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Deep Learning and Multimodal Large Language Models in Tumor/Cancer Diagnosis, Prediction and Prognosis

edited by

Steven L. Fernandes

submission deadline 31 Aug 2026 | 3 articles | Viewed by 4942 | Submission Open

Keywords: diagnosis; prognosis; tumor/cancer; deep learning; multimodal large language models

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Innovations in Diagnostic and Interventional Cardiology: Bridging Imaging, Physiology, and Therapy

edited by Samit Shah and

Natalija Odanovic

submission deadline 31 Aug 2026 | 4 articles | Viewed by 4563 | Submission Open

Keywords: EKG; CCTA; MRI; SPECT; PET; Echo; OCT; IVUS; QFR; angioIMR

(This special issue belongs to the Section Medical Imaging and Theranostics)

Predictive Biomarkers in Oncology

edited by

Jun Zhang

submission deadline 31 Aug 2026 | 7 articles | Viewed by 4465 | Submission Open

Keywords: predictive biomarkers; precision oncology; liquid biopsy; treatment response; biomarker validation

(This special issue belongs to the Section Clinical Laboratory Medicine)

Multimodal Imaging: Enhancing Precision Medicine Across Diverse Clinical Pathways

edited by

Mariano Scaglione

and Salvatore Masala

submission deadline 31 Aug 2026 | 3 articles | Viewed by 4282 | Submission Open

Keywords: CT; XR; CT US; MRI; functional MRI; PET; SPECT

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnostic Imaging of Autoimmune Diseases

edited by Simone Appenzeller

submission deadline 31 Aug 2026 | 1 articles | Viewed by 3783 | Submission Open

Keywords: autoimmune diseases; systemic lupus erythematosus; systemic sclerosis; diagnosis; imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Multidisciplinary Diagnostic Approaches to Infectious Pathologies in Surgical Specialties

edited by

Elena Adelina Toma

and

Octavian Enciu

submission deadline 31 Aug 2026 | 2 articles | Viewed by 3771 | Submission Open

Keywords: surgical infections; diagnostic advancements; antimicrobial resistance; molecular diagnostics; radiological imaging; microbiological assays; AI-driven diagnostics

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

The Future of Cardiac Imaging in the Diagnosis, 2nd Edition

edited by

Grigorios Korosoglou

submission deadline 31 Aug 2026 | 2 articles | Viewed by 3697 | Submission Open

Keywords: cardiovascular imaging; diagnosis and management; early detection; risk stratification; emerging technologies

(This special issue belongs to the Section Medical Imaging and Theranostics)

Eye Disease: Diagnosis, Management, and Prognosis—2nd Edition

edited by

Adam Wylęgała

submission deadline 31 Aug 2026 | 7 articles | Viewed by 3293 | Submission Open

Keywords: eye disease; diagnosis; prognosis; OCT

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in the Diagnosis and Management of Pediatric Diseases: 2nd Edition

edited by

Elena Tarca

submission deadline 31 Aug 2026 | 6 articles | Viewed by 3231 | Submission Open

Keywords: pediatrics; neonatal medicine; congenital malformations; pediatric orthopedics and trauma; pediatric oncology; pediatric surgery; pediatric urology

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

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