Advances in Diagnosis and Management of Hepatitis

A Special Issue of Diagnostics (ISSN 2075-4418) belonging to the section "Diagnostic Microbiology and Infectious Disease".

Deadline for manuscript submissions: 31 December 2026 | Viewed by 1975

Editor

1. Center of Liver Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China
2. Beijing Key Laboratory of Emerging Infectious Diseases, Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China
Interests: MAFLD; CHB; liver cirrhosis; recompensation of cirrhosis
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Special Issue Information

Dear Colleagues,

We invite you contribute a paper to our Special Issue, entitled "Advances in Diagnosis and Management of Hepatitis." Given your significant contributions to this field, we believe your perspective would be an invaluable addition to this collection.

This Special Issue primarily focuses on latest advances, new concepts, and novel strategies in the clinical diagnosis and follow-up management of various types of hepatitis (viral hepatitis, non-alcoholic viral hepatitis, drug-induced liver injury, autoimmune hepatitis, metabolic-associated fatty liver disease, alcoholic liver disease). This Special Issue will focus on clinical research, as well as basic research findings with potential clinical applications.

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following: internal medicine, molecular biology, and pathogen biology.

We look forward to receiving your contributions.

Dr. Qi Wang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • viral hepatitis
  • hepatitis B virus hepatitis
  • drug-induced liver injury
  • autoimmune hepatitis
  • metabolic-associated fatty liver disease
  • alcoholic liver disease
  • diagnosis
  • follow-up management

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Published Papers (1 paper)

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Review

28 pages, 4629 KB  
Review
Multiparametric Ultrasound in Chronic Viral Hepatitis: From Fibrosis and Portal Hypertension to Steatosis and Focal Lesion Characterisation
by Krystian Mirowski, Andrzej Fedak, Jacek Czepiel, Jan Jamroś and Michal Kukla
Diagnostics 2026, 16(16), 2502; https://doi.org/10.3390/diagnostics16162502 - 7 Aug 2026
Viewed by 1504
Abstract
Chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infection remain leading causes of cirrhosis and hepatocellular carcinoma (HCC) worldwide, and continue to represent a major challenge despite the growing contribution of alcohol-related and metabolic dysfunction-associated steatotic liver disease. Direct-acting antivirals now [...] Read more.
Chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infection remain leading causes of cirrhosis and hepatocellular carcinoma (HCC) worldwide, and continue to represent a major challenge despite the growing contribution of alcohol-related and metabolic dysfunction-associated steatotic liver disease. Direct-acting antivirals now cure most patients with chronic HCV infection, while nucleos(t)ide analogues durably suppress HBV replication, producing a rapidly expanding population of treated and cured patients. Many nonetheless retain residual fibrosis, portal hypertension and long-term cancer risk, creating a need for non-invasive long-term liver assessment. Multiparametric ultrasound (MPUS) integrates the evaluation of morphology, fibrosis, steatosis, haemodynamics and perfusion within a single examination. This narrative review summarises the evidence supporting MPUS in chronic viral hepatitis, covering elastographic fibrosis assessment, Baveno VII liver and spleen stiffness criteria for clinically significant portal hypertension, contrast-enhanced ultrasound characterisation of focal liver lesions, and emerging techniques such as microvascular and viscosity-sensitive imaging. Particular attention is given to the confounding effect of inflammatory activity on liver stiffness. MPUS is presented here as a proposed evaluation framework for organising complementary measurements within a single examination, and not as an approach of demonstrated clinical superiority: no comparative or outcome-based study has yet shown that acquiring these parameters together improves clinical decisions relative to the individual techniques applied according to current guidelines. Within this framework, the most plausible role of MPUS in the elimination era is longitudinal assessment of the treated liver, a proposition that requires prospective validation against clinical endpoints. Full article
(This article belongs to the Special Issue Advances in Diagnosis and Management of Hepatitis)
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