Pathological and Clinical Features of Non-Small Cell Lung Cancer

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Clinical Diagnosis and Prognosis".

Deadline for manuscript submissions: 31 July 2026 | Viewed by 2

Special Issue Editor


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Guest Editor
Department of Thoracic Surgery, Barts Thorax Centre, St. Bartholomew's Hospital, West Smithfield, London EC1A 7BE, UK
Interests: thoracic oncology; thoracic surgery; minimally invasive surgery; vats surgery; robotic surgery; sublobar resection; segmentectomy
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Special Issue Information

Dear Colleagues,

Non-small cell lung cancer (NSCLC) remains the leading cause of cancer-related mortality worldwide, and its management increasingly depends on the integration of advanced imaging, pathological assessment, surgical strategy, and systemic therapy. Innovations in CT, PET/CT, radiomics, endoscopic staging (EBUS), and navigational bronchoscopy have transformed early detection, staging, and operability assessment.

In parallel, molecular pathology and an improved understanding of tumour biology—including invasiveness patterns, spread through air spaces (STAS), and predictive biomarker expression—are reshaping surgical decision-making and prognostic evaluation. The emergence of perioperative immunotherapy and targeted therapies has further reinforced the need for a precision-based, multidisciplinary approach to NSCLC management.

This Special Issue will bring together contemporary research and expert reviews illustrating how radiology, pathology, surgery, and oncology converge to optimise the diagnosis and treatment of NSCLC. Topics of interest include advanced imaging and endoscopic diagnostic techniques, pathological and molecular predictors of outcomes, surgical strategies for early-stage NSCLC (including wedge resection, segmentectomy, and lobectomy), and the evolving role of immunotherapy in early and locally advanced disease. We welcome submissions that will enhance multidisciplinary understanding and support diagnostic-driven, personalised clinical decision-making in NSCLC.

Dr. Luigi Ventura
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • non-small cell lung cancer
  • NSCLC
  • thoracic oncology
  • radiology
  • EBUS
  • navigational bronchoscopy
  • lung pathology
  • molecular biomarkers
  • STAS
  • immunotherapy
  • segmentectomy
  • lobectomy
  • perioperative therapy

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Published Papers

This special issue is now open for submission.
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