Advances in Oxidative Stress and Inflammation

Dear Colleagues,

Oxidative stress and inflammation are intricately linked processes that play pivotal roles in the onset and progression of numerous human diseases, including cancer, cardiovascular and neurodegenerative disorders, metabolic dysfunction, and chronic lung conditions. Excessive production of reactive oxygen and nitrogen species disrupts redox balance, modifies biomolecules, and activates signaling pathways such as NF-κB, Nrf2, MAPKs, and inflammasomes, leading to sustained inflammatory responses and tissue injury. Recent advances in molecular biology, high-throughput omics, and imaging technologies have significantly expanded our understanding of the interplay between oxidative stress, immune responses, and cellular homeostasis. This Special Issue aims to gather original research and review articles addressing mechanistic insights, biomarkers, and therapeutic strategies targeting oxidative stress and inflammation. Topics of interest include redox-regulated signaling cascades, mitochondrial dysfunction, antioxidant defense mechanisms, epigenetic regulation, and novel pharmacological or natural compounds with anti-inflammatory and antioxidative properties. By integrating molecular, cellular, and translational studies, this collection will highlight emerging paradigms and therapeutic opportunities, ultimately advancing the development of innovative interventions to combat oxidative stress–driven inflammatory diseases.

Dr. Md. Sohanur Rahman
Guest Editor

Dr. Mohammed Daira
Co-Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the Special Issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Current Issues in Molecular Biology is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Publisher’s Notice

Following discussions between the Current Issues in Molecular Biology editorial office and the Guest Editor, a new Guest Editor, Dr. Mohammed Daira, has been added to the Special Issue. This change has been approved by the journal Editorial Board, and the Special Issue website has been updated accordingly on 3 August 2026. The Special Issue will continue to be handled by the new Guest Editor team in accordance with MDPI’s Special Issue and editorial policies.