Special Issues

Cells publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

Section
Search by Title/Keyword
 
Order results
Display
Results per page
Cellular and Molecular Mechanisms of Microglia/Macrophages in the Nervous System
edited by Emanuela Paldino
submission deadline 20 Apr 2026 | Viewed by 169 | Submission Open
Keywords: microglia; macrophages; neurological disorders
Stress-Induced Acute Immune Activation and Its Biological Consequences
edited by Ana Cicvaric
submission deadline 20 Apr 2026 | Viewed by 151 | Submission Open
Keywords: stress-induced immune signaling; acute immune activation; innate immune cell activation; cytokine response; cellular stress responses; inflammation and homeostasis
Signalling Mechanisms Regulating Cardiac Fibroblast Function
edited by Haofei Wang and
submission deadline 20 Apr 2026 | Viewed by 132 | Submission Open
Keywords: cardiac fibroblasts; myofibroblast activation; extracellular matrix remodeling; fibrosis; intercellular communication; mechanotransduction; single-cell and spatial insights; regeneration; therapeutic targeting
Regulatory Factors and Signaling Pathways of Anti-Tumor Immune Responses
edited by
submission deadline 20 Apr 2026 | Viewed by 94 | Submission Open
Keywords: anti-tumor immunity; immunotherapy; immune checkpoint blockade; immune receptor and ligand; immune evasion; tumor immune microenvironment; inflammation; T-cell activation and inhibition; myeloid-derived suppressor cell; macrophage; dendritic cell
(This special issue belongs to the Section Cellular Immunology)
Cellular and Molecular Mechanisms of Idiopathic Pulmonary Fibrosis
edited by and
submission deadline 20 Apr 2026 | Viewed by 80 | Submission Open
Keywords: idiopathic pulmonary fibrosis; fibroblast activation; epithelial– mesenchymal interaction; extracellular matrix remodeling; inflammation; signaling pathways; biomarkers; molecular targets; autophagy; senescence
Molecular Mechanisms and Treatment Strategies in Metabolic Syndromes and Neurological Disorders submission deadline 20 Apr 2026 | Viewed by 71 | Submission Open
Keywords: neurological disorders; metabolic syndromes; neurodegenerative disease; systems biology; precision medicine; target therapy
(This special issue belongs to the Section Cellular Neuroscience)
New Mechanistic Insights and Novel Therapeutic Options for Pulmonary Vascular Disease (PVD)
edited by
submission deadline 20 Apr 2026 | Viewed by 58 | Submission Open
Keywords: pulmonary vascular disease; pulmonary hypertension; pulmonary arterial hypertension; vascular contraction; vascular remodeling
Therapeutic Targets in Glioblastoma
edited by Candice Mazewski and
submission deadline 25 Apr 2026 | 5 articles | Viewed by 19219 | Submission Open
Keywords: glioblastoma; signaling targets; blood-brain-barrier; complementary and alternative medicine; combination therapy; glioma stem cells; progression; resistance; nutrient-sensing
(This special issue belongs to the Section Cellular Neuroscience)
Identifying Functional Genomics and Pathways in Cancer Pathogenesis and Therapy Resistance
edited by and Ramkrishna Mitra
submission deadline 25 Apr 2026 | 2 articles | Viewed by 4104 | Submission Open
Keywords: functional genomics; cancer signaling pathways; targeted therapy; drug resistance; tumor microenvironment; oncogenomics; acquired resistance; tumor mutations
(This special issue belongs to the Section Cellular Pathology)
Regulation of Vascular Endothelial Growth Factor (VEGF) and Its Receptor (VEGFR) in Angiogenesis
edited by Alessandra Loda and
submission deadline 25 Apr 2026 | 1 articles | Viewed by 3057 | Submission Open
Keywords: vascular endothelial growth factor (VEGF); VEGF receptors (VEGFRs); angiogenesis; endothelial cells; anti-angiogenic therapies; VEGFR inhibitors
Molecular and Cellular Insights into Platelet Function, 2nd Edition submission deadline 25 Apr 2026 | 3 articles | Viewed by 774 | Submission Open
Keywords: platelet; wound healing; fibrinolysis; regeneration and tissue remodeling; angiogenesis; lymphatic development; inflammation and immunity
Retinal Pigmented Epithelium (RPE) and the Choroid: Players and Partners for Vision
edited by and Janet R. Sparrow
submission deadline 25 Apr 2026 | Viewed by 651 | Submission Open
Keywords: retinal pigment epithelium; photoreceptor cell; choroid; Bruch’ s membrane; neural retina; visual cycle; phagocytosis; secretion; organelles; mitochondria; retinoid; melanin; albinism; age-related macular degeneration
(This special issue belongs to the Section Tissues and Organs)
Stem Cells in Action: Unlocking the Potential of Next-Generation Therapies
edited by George G. Koliakos
submission deadline 25 Apr 2026 | Viewed by 126 | Submission Open
Keywords: stem cell biology; differentiation and niche interaction; secretome/extracellular vesicles; organoids and disease modeling; regenerative medicine and tissue repair; immunomodulation and antimicrobial function; cell-based therapies and  cGMP translation; scaffold and biomaterial integration
(This special issue belongs to the Section Stem Cells)
Gene Editing Using Synthetic Nucleic Acids
edited by Debmalya Bhunia
submission deadline 25 Apr 2026 | Viewed by 83 | Submission Open
Keywords: gene editing; synthetic nucleic acids; genetic diseases; targeted gene therapy; antisense binding
(This special issue belongs to the Section Cell and Gene Therapy)
Cell Death Mechanisms and Therapeutic Opportunities in Glioblastoma
edited by
submission deadline 30 Apr 2026 | 21 articles | Viewed by 77603 | Submission Open
Keywords: apoptosis; autophagy; cell death mechanisms; cell signaling; glioblastoma; therapeutic opportunities
(This special issue belongs to the Section Cellular Neuroscience)
Unlocking the Secrets Behind Drug Resistance at the Cellular Level submission deadline 30 Apr 2026 | 5 articles | Viewed by 21923 | Submission Open
Keywords: molecular mechanisms; effective treatments; drug tests; bacterial resistance; chemoresistance
(This special issue belongs to the Section Cellular Immunology)
Gastrointestinal Cancer: From Cellular and Molecular Mechanisms to Therapeutic Opportunities submission deadline 30 Apr 2026 | 7 articles | Viewed by 14209 | Submission Open
Keywords: colorectal cancer; gastric cancer; liver cancer; pancreatic cancer; tumor microenvironment; cytokines; epigenetic; checkpoint inhibitors; biomarkers; immunotherapy
(This special issue belongs to the Section Cellular Pathology)
Eosinophils and Their Role in Allergy and Related Diseases
edited by
submission deadline 30 Apr 2026 | 6 articles | Viewed by 10402 | Submission Open
Keywords: eosinophils; asthma; allergy; inflammation; anti-eosinophil biologics; interleukin-5; interleukin-5 receptor; degranulation; mediator release
(This special issue belongs to the Section Cellular Immunology)
Research on T Cells in Skin Inflammatory Disorders
edited by and Qing-Sheng Mi
submission deadline 30 Apr 2026 | 1 articles | Viewed by 8321 | Submission Open
Keywords: T cell; vitiligo; atopic dermatitis; T cell lymphoma
(This special issue belongs to the Section Cellular Immunology)
Onco-Hematology and Immunotherapy
edited by and Régis T. Costello
submission deadline 30 Apr 2026 | 2 articles | Viewed by 6466 | Submission Open
Keywords: immunotherapy; onco-hematology; CAR T cells; NK cells; immune system; immune cells; leukemias; lymphomas
(This special issue belongs to the Section Cellular Immunology)
Advances in Cardiomyocyte and Stem Cell Biology in Heart Disease
edited by Ki Ho Park
submission deadline 30 Apr 2026 | 4 articles | Viewed by 4507 | Submission Open
Keywords: cardiomyocytes; stem cells; heart disease; regenerative medicine; ion channels; protein therapeutics; bioengineering; molecular biology
(This special issue belongs to the Section Cells of the Cardiovascular System)
Control of Gene Expression by Co-Transcriptional Processes in Cell Homeostasis and Cell Fate Specification: Second Edition
edited by
submission deadline 30 Apr 2026 | 2 articles | Viewed by 4277 | Submission Open
Keywords: gene transcription; transcription elongation; RNA processing; RNA modification; RNA transport; lncRNA; histone modification; biomolecular condensates; diseases associated with dysregulation of gene regulation
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
New Discoveries in Calcium Signaling-Related Neurological Disorders
edited by Matheus De Castro Fonseca
submission deadline 30 Apr 2026 | 1 articles | Viewed by 3338 | Submission Open
Keywords: Ca2+ signaling; neurons; neurological disorders; intracellular signaling; synaptic dysfunction
(This special issue belongs to the Section Cellular Neuroscience)
Cellular Mechanisms and Targeted Therapy of Acute Myeloid Leukemia
edited by
submission deadline 30 Apr 2026 | 2 articles | Viewed by 3275 | Submission Open
Keywords: Acute Myeloid Leukemia (AML); molecular targets; gene therapy; drug resistance; targeted therapy; leukemia stem cells; oncogenic mutations; apoptosis; cell cycle regulation
(This special issue belongs to the Section Cellular Pathology)
Immune Cells from Pluripotent Stem Cells
edited by
submission deadline 30 Apr 2026 | 2 articles | Viewed by 3224 | Submission Open
Keywords: pluripotent stem cells; T cells; B cells; macrophages; natural killer (NK) cells; dendritic cells; megakaryocytes; platelets
(This special issue belongs to the Section Stem Cells)
Modulation of P2X Receptors: Emerging Implications for Cellular Signaling and Disease Management
edited by Luca Antonioli and
submission deadline 30 Apr 2026 | 2 articles | Viewed by 2799 | Submission Open
Keywords: purinergic receptors; purinergic signaling; adenosine; ATP; ADP
Advancements in Cardiac Metabolism
edited by
submission deadline 30 Apr 2026 | 2 articles | Viewed by 2533 | Submission Open
Keywords: cardiovascular disease; metabolism; fatty acids; heart failure; mitochondrial dysfunction
(This special issue belongs to the Section Cells of the Cardiovascular System)
Pathogenesis and Novel Therapies in Epithelial Cancers
edited by Jung Wook Park and Sanjeevram Dhandapani
submission deadline 30 Apr 2026 | 1 articles | Viewed by 2475 | Submission Open
Keywords: transformation; malignant; oncogene; tumor suppressor; molecular mechanisms; epigenetic; metabolic; immune; biomarkers; personalized medicine; primary cells; small-molecule inhibitor
(This special issue belongs to the Section Cellular Pathology)
Telomere Maintenance and Metabolic Reprogramming in the Tumor Microenvironment
edited by and Jiyue Zhu
submission deadline 30 Apr 2026 | 1 articles | Viewed by 1849 | Submission Open
Keywords: telomere maintenance mechanisms (TMM); tumor microenvironment (TME); telomerase activation; alternative lengthening of telomeres (ALT); cancer metabolism; mitochondrial dysfunction; redox homeostasis; DNA damage response (DDR); epigenetic regulation; cancer therapeutics; senescence-associated secretory phenotypes (SASPs)
(This special issue belongs to the Section Cell Microenvironment)
The Artificial Intelligence to the Rescue of Cancer Research submission deadline 30 Apr 2026 | 1 articles | Viewed by 1774 | Submission Open
Keywords: cancer research; artificial intelligence; personalized medicine; multi-omics data integration; AI-driven drug discovery; precision medicine
(This special issue belongs to the Section Cell Methods)
Molecular Mechanisms Underlying Inflammatory Pain
edited by
submission deadline 30 Apr 2026 | 1 articles | Viewed by 1554 | Submission Open
Keywords: molecular mechanisms; inflammatory pain; nociception; neuronal sensitization; neuroimmune interactions
Mechanisms Underlying Cell Growth and Development
edited by
submission deadline 30 Apr 2026 | 2 articles | Viewed by 1349 | Submission Open
Keywords: cell growth; cell development; cell differentiation; cell cycle; mitosis; meiosis; molecular rearrangements; chromosomes; gene expression
Spatial Biology: Decoding Cellular Complexity in Tissues submission deadline 30 Apr 2026 | 1 articles | Viewed by 1087 | Submission Open
Keywords: spatial biology; spatial tissue profiling; proteomics; transcriptomics; cell and tissue
(This special issue belongs to the Section Tissues and Organs)
Autophagy in Neurological Disorders submission deadline 30 Apr 2026 | 1 articles | Viewed by 672 | Submission Open
Keywords: autophagy; selective autophagy; neurodegeneration; proteostasis; lysosomes; aging; oxidative stress; aging; biomarkers; pharmacological agents
(This special issue belongs to the Section Cellular Neuroscience)
Autoimmune Diseases: Immune Cells and Genetic and Epigenetic Regulations
edited by
submission deadline 30 Apr 2026 | 1 articles | Viewed by 553 | Submission Open
Keywords: autoimmune diseases; immune cells; lymphocytes; antigen-presenting cells; natural killer cells; innate lymphoid cells; epigenetic modifications; autoimmunity
(This special issue belongs to the Section Cellular Immunology)
Role of Gamma Delta T Cells in Immunotherapy
edited by and Wenwei Tu
submission deadline 30 Apr 2026 | Viewed by 415 | Submission Open
Keywords: gamma delta T cells; adoptive cell therapy; chimeric antigen receptors; bispecific antibodies; cancer immunotherapy; tumor microenvironment; phosphoantigens; butyrophilin 2A1/3A1; virus infection; multidrug-resistant bacteria; extracellular vesicles
(This special issue belongs to the Section Cellular Immunology)
Advances in Bacterial Cell Biophysics: Metabolic Engineering and Host Interactions
edited by Shahid Khan
submission deadline 30 Apr 2026 | Viewed by 396 | Submission Open
Keywords: bacterial cell biophysics; mechanical properties; biophysical techniques; host interactions; metabolic engineering
Synaptic Dysregulation in Nervous System Disorders
edited by Pragya Goel
submission deadline 30 Apr 2026 | Viewed by 340 | Submission Open
Keywords: synapses; synaptic transmission; synaptic plasticity; neurodegeneration; neuropsychiatric disorders; neurodevelopmental diseases
(This special issue belongs to the Section Cellular Neuroscience)
Hematologic Diseases: From Cellular and Molecular Mechanisms to Therapies submission deadline 30 Apr 2026 | 1 articles | Viewed by 299 | Submission Open
Keywords: hematologic diseases; mechanisms; therapies
Novel Therapies and Biomarkers for Rare Diseases
edited by Reena Kartha
submission deadline 30 Apr 2026 | Viewed by 276 | Submission Open
Keywords: rare diseases; translational research; novel therapies; biomarker discovery; precision medicine
Advances in Liquid Biopsy for Early Detection and Monitoring of Cancer
edited by Nicola Normanno, and
submission deadline 30 Apr 2026 | Viewed by 234 | Submission Open
Keywords: ctDNA; circulating tumor cells; microRNAs; exosomes; methylation; fragmentomics; early detection; minimal residual disease; artificial intelligence
Interleukin-1 Signaling in Cancer: Novel Mechanisms and Therapeutic Opportunities
edited by Afshan Fathima Nawas and
submission deadline 30 Apr 2026 | Viewed by 232 | Submission Open
Keywords: interleukin-1 signaling; tumor microenvironment; inflammatory pathways; cytokine networks; cancer cell proliferation; epigenetic regulation in cancer; non-coding RNAs; immune modulation; cancer metabolism
The Role of Integrins and Small GTPases in Health and Disease
edited by
submission deadline 30 Apr 2026 | Viewed by 189 | Submission Open
Keywords: cell signaling; integrins; cell adhesion; integrins diseases; infectious diseases
Psilocybe Mushrooms Constituents—Therapeutic Implications
edited by and Janet Schloss
submission deadline 30 Apr 2026 | Viewed by 185 | Submission Open
Keywords: Psilocybe mushrooms; psilocybin; pre-clinical research; neurodegeneration
(This special issue belongs to the Section Plant, Algae and Fungi Cell Biology)
Kidney Development: Cellular and Molecular Insights submission deadline 30 Apr 2026 | Viewed by 131 | Submission Open
Keywords: kidney development; nephrogenesis; single-cell RNA-seq/ATAC-seq; congenital anomalies of the kidney and urinary tract (CAKUT); blood pressure regulation
Glycosylation and Glycoproteins in Human Disease
edited by and
submission deadline 30 Apr 2026 | Viewed by 131 | Submission Open
Keywords: glycobiology; glycosylation; glycoproteins; glycolipids; glycan biomarkers; congenital disorders of glycosylation (cdg); immune modulation; glycan profiling; glycoengineering; host– pathogen interactions; therapeutic glycoproteins; bioorthogonal chemistry
Advances in Neuropathology: Cellular, Molecular and Precision Mechanisms in Neurodegenerative Diseases submission deadline 30 Apr 2026 | Viewed by 120 | Submission Open
Keywords: neurodegeneration; Alzheimer's disease; Parkinson's disease; glial cells; synaptic dysfunction; protein aggregation; lysosomal function; autophagy; precision medicine
Advancing Breast Cancer Research: Multi-Omics, AI, and Emerging Cellular Mechanisms
edited by Rahul Sanawar, and Satheesh Kumar Sengodan
submission deadline 30 Apr 2026 | Viewed by 116 | Submission Open
Keywords: breast cancer; cancer stem cells; cell plasticity; immune evasion; drug resistance; tumor microenvironment; non-coding RNAs; circulating tumor cells (CTC); circulating tumor DNA (ctDNA); exosomes; signaling pathways (e.g.; PI3K/AKT; MAPK); targeted therapy; immunotherapy
Molecular Mechanisms of Autophagy, Apoptosis and Senescence and Therapeutic Advances in Cancer Progression submission deadline 30 Apr 2026 | Viewed by 113 | Submission Open
Keywords: cancer progression; cell death; senescence; cancer therapy
Noncoding RNAs: Immunity, Mechanisms, and Biomarker Potential
edited by
submission deadline 30 Apr 2026 | Viewed by 113 | Submission Open
Keywords: noncoding RNAs (ncRNAs); MicroRNAs (miRNAs); long noncoding RNAs (lncRNAs); circular RNAs (circRNAs); immune regulation; tumor microenvironment; immune checkpoints; cancer immunotherapy; liquid biopsy biomarkers; immune evasion
Back to TopTop