Stem Cells in Action: Unlocking the Potential of Next-Generation Therapies
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Stem Cells".
Deadline for manuscript submissions: 25 April 2026 | Viewed by 7
Special Issue Editor
Interests: stem cells; molecular biology of the cell; gerobiology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Stem cells, with their unique capacity for self-renewal, differentiation, and paracrine signaling, serve as foundational elements in modern biomedical science. This Special Issue will showcase groundbreaking research and expert perspectives on the multifaceted functions of stem cells in regenerative medicine, disease modeling, and therapeutic innovation. We particularly welcome contributions that elucidate the molecular and cellular mechanisms governing stem cell behavior—ranging from lineage commitment and niche interaction to immunomodulatory and antimicrobial functions—as well as studies investigating the therapeutic utility of stem cell-derived secretomes and extracellular vesicles, as well as the utility of organoid systems in personalized and general drug evaluation and tissue repair. Additionally, applications spanning tissue repair, scaffold-based engineering, and translational strategies—including cGMP-compliant protocols and clinical‑grade production—are of significant interest. By fostering dialogue across basic biology, bioengineering, and clinical translation, this Special Issue will spotlight innovations that harness stem cells’ intrinsic capabilities in tissue regeneration, disease intervention, and personalized medicine. We invite the original submission of research, reviews, methods, and perspectives that will advance our understanding of stem cell functions and pave the way for next-generation biomedical applications.
Dr. George G. Koliakos
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- stem cell biology
- differentiation and niche interaction
- secretome/extracellular vesicles
- organoids and disease modeling
- regenerative medicine and tissue repair
- immunomodulation and antimicrobial function
- cell-based therapies and cGMP translation
- scaffold and biomaterial integration
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