Molecular Mechanisms of Autophagy, Apoptosis and Senescence and Therapeutic Advances in Cancer Progression
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 30 April 2026 | Viewed by 71
Special Issue Editors
Interests: signaling cascades; prostate cancer; proliferation; cancer drugs, autophagy; apoptosis, senescence, virus-induced oncogenesis
Interests: chronic viral infections; chronic conditions; cellular senescence; molecular mechanisms of cell death; biomarkers of cancer progression; virus-induced oncogenesis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Programmed cell death and cellular senescence play critical roles in cancer development and progression. When cell death pathways are disrupted, cancer cells gain the ability to escape elimination and secure survival advantages. Meanwhile, senescence serves as a powerful anti-tumor barrier by halting unchecked cell proliferation—yet malignant cells that learn to bypass this safeguard advance disease progression and resist treatment. The intricate balance and crosstalk among these processes not only illuminate tumor biology but also highlight promising avenues for novel therapeutic strategies.
With this Special Issue, we invite researchers to contribute original studies and insightful reviews that push the boundaries of our understanding. Topics of interest include the molecular underpinnings of apoptosis, autophagy, and senescence in tumor development; key regulatory factors and signaling networks; innovative in vitro and in vivo models; the influence of these pathways on therapy resistance and tumor–microenvironment interactions; and emerging strategies that harness or target these processes for more effective cancer treatments.
Dr. Katerina Gioti
Prof. Dr. Apostolos Beloukas
Guest Editors
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- cancer progression
- cell death
- senescence
- cancer therapy
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