Pathogenesis and Novel Therapies in Epithelial Cancers

A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Pathology".

Deadline for manuscript submissions: 30 June 2025 | Viewed by 136

Special Issue Editors


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Guest Editor
Pathology, Clinical Science Departments & Cell Biology, Basic Science Departments, Duke University School of Medicine, Durham, NC, USA
Interests: functional genomics; prostate cancer; lung cancer; small-cell cancer; neuroendocrine cancer; genetically engineered disease model; transcriptome; epigenetics

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Guest Editor
Pathology, Clinical Science Departments & Cell Biology, Basic Science Departments, Duke University School of Medicine, Durham, NC, USA
Interests: oncology; inflammation-immune; nanotechnology; biomaterials and multi-omics

Special Issue Information

Dear Colleagues, 

Cancers can develop in various epithelial tissues. The most common types of epithelial cancers are breast cancer, prostate cancer, lung cancer, colorectal cancer, and skin cancer. Despite recent advancements in therapeutic strategies, such as targeted therapy, antibody–drug conjugates, CAR-T immunotherapy, nanoparticle-based drug delivery, and personalized medicine, these cancers remain life-threatening. Therefore, addressing how human epithelial cancers are initiated, developed, and differentiated, and the molecular factors behind them, can allow us to identify molecular vulnerabilities and utilize advanced therapeutic strategies to treat cancer patients efficiently. This can provide new insights into the genetic alterations, epigenetic mechanisms, metabolic changes, and immune system factors that contribute to cancer initiation, development, and progression. This Special Issue will highlight recent advancements and future directions in epithelial cancer research. We invite the submission of original articles and reviews on molecular mechanisms, diagnostics, therapeutic advances, and translational research, combining basic research with clinical applications.

Dr. Jung Wook Park
Dr. Sanjeevram Dhandapani
Guest Editors

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Keywords

  • transformation
  • malignant
  • oncogene
  • tumor suppressor
  • molecular mechanisms
  • epigenetic
  • metabolic
  • immune
  • biomarkers
  • personalized medicine
  • primary cells
  • small-molecule inhibitor

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Published Papers

This special issue is now open for submission.
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