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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Recent Advances in Endoscopic, Metabolomic, and Ultrasound Approaches to Gastrointestinal, Hepatic, and Pancreatic Tumors

edited by Ciprian Brisc and Nadim Al Hajjar

submission deadline 15 Nov 2026 | 2 articles | Viewed by 8568 | Submission Open

Keywords: gastrointestinal, hepatic and pancreatic tumors; metabolomics; endoscopy; ultrasound; elastography; molecular investigations and treatment; robotic surgery; laparoscopic surgery; early lesions; radiofrequency and microwave ablation; irreversible electroporation; cryoablation; targeted chemo- or radio-embolization

(This special issue belongs to the Section Cancer Therapy)

Molecular and Genetic Diagnosis and Targeted Therapy of Myeloproliferative Neoplasms (2nd Edition)

edited by

Jinming Song

and

Ling Zhang

submission deadline 15 Nov 2026 | 3 articles | Viewed by 7048 | Submission Open

Keywords: myeloproliferative neoplasm; chronic myeloid leukemia; polycythemia vera; essential thrombocythemia; primary myelofibrosis; MPN; CML; PMF; PV; ET

(This special issue belongs to the Section Molecular Cancer Biology)

Advances in Locoregional Therapies for Gastrointestinal Cancer Metastases

edited by

Mazin Al-Kasspooles

submission deadline 15 Nov 2026 | 3 articles | Viewed by 3277 | Submission Open

Keywords: gastrointestinal cancer metastases; locoregional therapies; interventional radiology; endoscopy; radiation therapy; invasive operations; cytoreductive surgery (CRS); intraperitoneal chemotherapy (IP); heated intraperitoneal chemotherapy (HIPEC); tumor debulking; stereotactic body radiation therapy (SBRT); selective internal radiation therapy (SIRT)

(This special issue belongs to the Section Methods and Technologies Development)

Oncogenesis of Lymphoma (2nd Edition)

edited by

Annunziata Gloghini

and Giancarlo Pruneri

submission deadline 15 Nov 2026 | 1 articles | Viewed by 1069 | Submission Open

Keywords: lymphomagenesis; molecular genetics; immunology; molecular virology; KSHV/HHV8; EBV; HIV; pathogenetic pathways; genotypic subgroups; tumor microenvironment; follicular lymphoma; mantle cell lymphoma; diffuse large B-cell lymphoma; targeted therapy; drug target

(This special issue belongs to the Section Molecular Cancer Biology)

Translational Research and Clinical Trials in Gastric Cancer: Advances and Future Directions

edited by Yanghee Woo

submission deadline 15 Nov 2026 | 1 articles | Viewed by 1047 | Submission Open

Keywords: gastric cancer; multidisciplinary management; conversion gastrectomy; molecular biomarker testing; diagnostic laparoscopy; neoadjuvant therapy; upfront surgery; intraperitoneal treatment

(This special issue belongs to the Section Clinical Research in Cancer)

Gene Editing and Delivery for Cancer Therapy (2nd Edition)

edited by

Yong Teng

and

Yamin Li

submission deadline 15 Nov 2026 | Viewed by 492 | Submission Open

Keywords: gene therapy; gene editing; gene delivery; oncolytic viruses; nanomaterial; peptides; nanostructures; exosomes; translational science

(This special issue belongs to the Section Cancer Therapy)

Targeting Head and Neck Cancer: From Tumor Microenvironment to Therapy Resistance

edited by

Ratna B. Ray

and

Subhayan Sur

submission deadline 15 Nov 2026 | Viewed by 488 | Submission Open

Keywords: head and neck squamous cell carcinoma (HNSCC); tumor microenvironment (TME); therapy resistance; HPV-associated cancers; immunotherapy; cancer-associated fibroblasts (CAFs); tumor heterogeneity; precision oncology; biomarkers; metastasis

Evaluating the Clinical Impact of Robotic Surgery in the Management of Colorectal Cancer

edited by

Héctor Guadalajara

and Miguel Leon-Arellano

submission deadline 15 Nov 2026 | Viewed by 466 | Submission Open

Keywords: robotic surgery; colorectal cancer; oncological outcomes; surgical technique; laparoscopic comparison; margin status; postoperative recovery; quality of life; intraoperative imaging; surgical navigation; learning curve; complications; cost-effectiveness; surgical training; technological innovation

(This special issue belongs to the Section Clinical Research in Cancer)

Impact of Anesthetic/Analgetic Drugs on Cancer Recurrence

edited by

Alain Borgeat

and

Effrossyni Gina Votta-Velis

submission deadline 15 Nov 2026 | Viewed by 210 | Submission Open

Keywords: effect of amide-type local anesthetics; role of IV and analgesic drugs; opioids: pro or anti-cancer

Personalization of Non-Melanoma Skin Cancer Treatment

edited by

Nicco Krezdorn

and Frederik Penzien Wainer Mamsen

submission deadline 20 Nov 2026 | 1 articles | Viewed by 894 | Submission Open

Keywords: personalized medicine; non-melanoma skin cancer; local treatment

(This special issue belongs to the Section Cancer Therapy)

The Pathologic Diagnosis and Clinical Therapy of Neuroendocrine Tumors: 2nd Edition

edited by

Salvatore Tafuto

Ottavia Clemente

and

Annabella Di Mauro

submission deadline 20 Nov 2026 | Viewed by 305 | Submission Open

Keywords: neuroendocrine neoplasms; molecular mechanisms; cancer pathogenesis; tumorigenesis; diagnosis; molecular and cellular heterogeneity; predictive biomarkers; animal models and of neuroendocrine cancer; diagnostic clinical oncology; genomic characterization; clinical biomarkers; biomarkers of drug response; epigenetic biomarkers; targeted therapy; tumor immunity; molecular oncology; clinical therapy

Contemporary Surgical Management of Thyroid Cancer: Toward Precision and Multidisciplinary Care

edited by Marco Puccini and Benard Gjeloshi

submission deadline 20 Nov 2026 | Viewed by 276 | Submission Open

Keywords: thyroid cancer; surgery

(This special issue belongs to the Section Cancer Therapy)

Advances in Molecular Mechanisms of Gastrointestinal Tumors (2nd Edition)

edited by

Shihori Tanabe

submission deadline 25 Nov 2026 | 5 articles | Viewed by 10136 | Submission Open

Keywords: molecular mechanism; gastrointestinal tumor; gastric cancer; colorectal cancer; esophageal cancer; tumor microenvironment; molecular network; molecular pathway; pathway network; signal transduction

(This special issue belongs to the Section Molecular Cancer Biology)

Radiologic Staging and Surgical Decision-Making in the Era of Neoadjuvant Therapy for Breast Cancer

edited by

Damiano Gentile

submission deadline 25 Nov 2026 | 1 articles | Viewed by 806 | Submission Open

Keywords: radiologic staging; neoadjuvant therapy; breast cancer; breast-conserving surgery; mastectomy; targeted axillary dissection; sentinel lymph node biopsy; axillary lymph node dissection; magnetic resonance imaging; surgical de-escalation

(This special issue belongs to the Section Cancer Therapy)

Infectious Pathogens and Cancer

edited by

W. Martin Kast

submission deadline 25 Nov 2026 | Viewed by 314 | Submission Open

Keywords: infectious cancer pathogens; related topics in immunology; virology; epidemiology; (therapeutic) vaccines; oncogenesis; screening; therapy

(This special issue belongs to the Section Infectious Agents and Cancer)

Cancer Cells Fostered Microenvironment in Metastasis (2nd Edition)

edited by

Lin Ye

submission deadline 25 Nov 2026 | Viewed by 292 | Submission Open

Keywords: cancer cells; tumour microenvironment; metastasis; fibroblast; immune cells; extracellular ma-trix; adhesion; migration; invasion; drug resistance; target therapy

(This special issue belongs to the Section Cancer Metastasis)

Treatment and Prognosis of Pediatric Medulloblastoma

edited by Marwa Ismail

submission deadline 25 Nov 2026 | Viewed by 237 | Submission Open

Keywords: pediatric medulloblastoma; proteomics; radiogenomics

(This special issue belongs to the Section Pediatric Oncology)

Breast Cancer Screening: Global Practices and Future Directions

edited by Rudolf Morant

submission deadline 26 Nov 2026 | 3 articles | Viewed by 6747 | Submission Open

Keywords: mammography screening; organized screening programs; tomosynthesis; 2D mammography; artificial intelligence; personalized screening

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

The Role of Cysteine Cathepsins in Cancer Progression

edited by

Mohammed Aufy

and Ramadan Faried Abdelaziz

submission deadline 26 Nov 2026 | Viewed by 338 | Submission Open

Keywords: cysteine cathepsins; cancer progression; tumor microenvironment; metastasis; lysosomal enzymes; protease inhibitors; drug resistance; targeted therapy

(This special issue belongs to the Section Molecular Cancer Biology)

Diagnosis and Treatment of Myeloid Neoplasms

edited by Laura Cicconi

submission deadline 27 Nov 2026 | 2 articles | Viewed by 2250 | Submission Open

Keywords: myeloid neoplasms; diagnostic approaches; prognostication; heterogeneous

New Insights in Esophageal Cancer Diagnosis and Treatment

edited by

Virendra Joshi

submission deadline 27 Nov 2026 | 1 articles | Viewed by 1859 | Submission Open

Keywords: esophageal cancer; diagnosis; targeted screening; endoscopic treatment

(This special issue belongs to the Section Cancer Therapy)

Breast Cancer Bone Metastasis

edited by Allan Lipton and Louis Costa

submission deadline 27 Nov 2026 | 1 articles | Viewed by 548 | Submission Open

Keywords: bone metastases in breast cancer; mechanisms; prevention; treatment; bone-targeted agents; imaging; surgery of bone metastases; radiotherapy of bone metastases

(This special issue belongs to the Section Cancer Metastasis)

Perioperative Care in Gynecologic Oncology: 2nd Edition

edited by Nikolaos Thomakos and

Vasilios Pergialiotis

submission deadline 28 Nov 2026 | 2 articles | Viewed by 8116 | Submission Open

Keywords: enhanced recovery; ERAS; immunonutrition; prehabilitation; gynecologic oncology; minimally invasive surgery

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Human Papillomavirus (HPV) and Related Cancer

edited by

Beata Biesaga

submission deadline 30 Nov 2026 | 12 articles | Viewed by 28737 | Submission Open

Keywords: HPV; carcinogenesis; methods of virus identification diagnostics; prognostification

(This special issue belongs to the Section Infectious Agents and Cancer)

Infectious Agents and Cancer in Children and Adolescents

edited by

Emmanouel Hatzipantelis

and Eleni Tsotridou

submission deadline 30 Nov 2026 | 4 articles | Viewed by 20226 | Submission Open

Keywords: infectious agents; immune system; tumor development; immunological memory; oncolytic viruses

(This special issue belongs to the Section Infectious Agents and Cancer)

Epidemiology of Cancer and Risk Factors: Pushing Boundaries in Public Health Research and Policy

edited by

The Phuong Nguyen

submission deadline 30 Nov 2026 | 8 articles | Viewed by 17200 | Submission Open

Keywords: cancer epidemiology; risk factors; public health policy; cancer prevention; early detection; genetic determinants; environmental exposures; behavioral health; interdisciplinary approaches; innovative methodologies

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

New Findings in Targeting Cancer Proteins (Second Edition)

edited by

Maristella Maggi

and

Claudia Scotti

submission deadline 30 Nov 2026 | 3 articles | Viewed by 11082 | Submission Open

Keywords: monoclonal antibodies; protein target; immunotherapy; signaling blockade; targeted therapy

(This special issue belongs to the Section Cancer Therapy)

Advances in the Diagnosis and Treatment of Prostate Cancer: From Biomarkers to Precision Surgery

edited by Stamatios N. Katsimperis and

Lazaros Tzelves

submission deadline 30 Nov 2026 | 7 articles | Viewed by 9193 | Submission Open

Keywords: prostate cancer; precision medicine; molecular biomarkers; risk stratification; robotic surgery; artificial intelligence; genomics; personalized treatment; imaging modalities; multidisciplinary approach

(This special issue belongs to the Section Cancer Therapy)

The Genetic Analysis and Clinical Therapy in Lung Cancer: 2nd Edition

edited by

Francesca Colombo

and Frullanti Elisa

submission deadline 30 Nov 2026 | 1 articles | Viewed by 8698 | Submission Open

Keywords: lung cancer; biomarkers; genetic variants; innovative technologies; targeted therapy; immunotherapy; personalized therapy; survival; liquid biopsy pharmacogenomics

(This special issue belongs to the Section Cancer Therapy)

Next-Generation Cancer Therapies

edited by

Achilleas Mitrakas

, Ioannis Lamprou and Erasmia Xanthopoulou

submission deadline 30 Nov 2026 | 2 articles | Viewed by 8468 | Submission Open

Keywords: cancer; current therapies; cancer cells metabolism; autophagy; immunotherapy; targeted treatments; oncolytic viruses; vaccines

(This special issue belongs to the Section Cancer Therapy)

Image-Guided Treatment of Liver Tumors

edited by

Maarten L. J. Smits

and Niek Wijnen

submission deadline 30 Nov 2026 | 6 articles | Viewed by 7741 | Submission Open

Keywords: liver; thermal ablation; radioembolization; TACE; yttrium-90; portal vein embolization; radiation oncology; interventional oncology

(This special issue belongs to the Section Cancer Therapy)

Artificial Intelligence for Network-Based Oncomarker Discovery and Cancer Prediction

edited by Oleg Blyuss

submission deadline 30 Nov 2026 | 4 articles | Viewed by 6577 | Submission Open

Keywords: artificial intelligence (AI); network-based biomarkers; graph neural networks (GNNs); multi-omic integration; cancer prediction; oncomarker discovery; prognostic and predictive biomarkers

(This special issue belongs to the Section Cancer Informatics and Big Data)

Real-World Evidence and Emerging Therapeutic Strategies in Refractory Metastatic Colorectal Cancer

edited by

Carlo Signorelli

submission deadline 30 Nov 2026 | 4 articles | Viewed by 6455 | Submission Open

Keywords: real-world evidence; refractory metastatic colorectal cancer; treatment resistance; third-line and beyond therapies; targeted therapies; immunotherapy; patient outcomes; clinical practice; biomarkers; precision oncology

(This special issue belongs to the Section Cancer Metastasis)

Ultrasound for Cancer Therapy

edited by Zhen Xu and

Natasha D. Sheybani

submission deadline 30 Nov 2026 | 7 articles | Viewed by 6422 | Submission Open

Keywords: HIFU; histotripsy; drug delivery; immunotherapy; sonodynamic therapy; blood brain barrier opening; sonobiopsy; cancer treatment; image-guided therapy

(This special issue belongs to the Section Cancer Therapy)

Novel Approaches to Machine Learning and Artificial Intelligence in Cancer Research and Care (2nd Edition)

edited by

Caroline Chung

and Chris J. Gibbons

submission deadline 30 Nov 2026 | 6 articles | Viewed by 6339 | Submission Open

Keywords: machine learning; deep learning; artificial intelligence; interpretable AI; data quality; metadata; data quality; cancer; MLOps; data science; real-world data

(This special issue belongs to the Section Cancer Informatics and Big Data)

Artificial Intelligence and Machine Learning in Lung Cancer

edited by

Jianjun Zhang

Jia Wu

and

Morteza Salehjahromi

submission deadline 30 Nov 2026 | 4 articles | Viewed by 6258 | Submission Open

Keywords: artificial intelligence; machine learning; lung cancer screening; low-dose CT; early detection

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Neuroscience of Brain Tumors

edited by Zefferino Rossini,

Miguel Segura Ginard

and Maria Pia Tropeano

submission deadline 30 Nov 2026 | 2 articles | Viewed by 6085 | Submission Open

Keywords: neurosurgery; neuroscience; brain tumors (gliomas, meningiomas, and pituitary tumors); neural pathway; neuroimaging; neurogenetics

Cancers in Dermatology—from Diagnosis to Treatment

edited by

Agnieszka Żebrowska

submission deadline 30 Nov 2026 | 3 articles | Viewed by 6065 | Submission Open

Keywords: dermato-oncology ; skin cancer immunotherapy ; cutaneous lymphoma ; molecular diagnostics ; multidisciplinary oncology care

Genetics of Ovarian Cancer (2nd Edition)

edited by

Stergios Boussios

and

Sola Adeleke

submission deadline 30 Nov 2026 | 3 articles | Viewed by 5184 | Submission Open

Keywords: epithelial ovarian cancer; genomics; epigenetics; translational research; biomarkers; DNA damage response; PARP inhibitors

(This special issue belongs to the Section Cancer Pathophysiology)

Image-Assisted High-Precision Radiation Oncology

edited by He C. Wang

submission deadline 30 Nov 2026 | 3 articles | Viewed by 4815 | Submission Open

Keywords: medical imaging; radiation oncology; artificial intelligence; radiomics; adaptation; tumor response

(This special issue belongs to the Section Cancer Therapy)

Decoding the Dynamic Matrix Complexity in Cancer

edited by

Nikos Karamanos

Zoi Piperigkou

and

Luisa Bracci

submission deadline 30 Nov 2026 | 3 articles | Viewed by 4731 | Submission Open

Keywords: extracellular matrix; cancer pathobiology; 3D spheroids/organoids; modeling tumor microenvironment complexity; matrix-based bioscaffolds; matrix remodeling; cell surface matrix mediators and effectors; matrix degrading enzymes; proteoglycans/glycosaminoglycans; collagen; matrix (glyco)proteins; molecular targeting

(This special issue belongs to the Section Tumor Microenvironment)

Multimodality Management of Sarcomas (2nd Edition)

edited by

Eelco de Bree

submission deadline 30 Nov 2026 | 3 articles | Viewed by 4130 | Submission Open

Keywords: sarcomas; multimodal; pathology; radiology; surgery; chemotherapy; radiotherapy

(This special issue belongs to the Section Cancer Therapy)

Advances in Neoadjuvant Chemotherapy and Radiotherapy for Breast Cancer: Surgical Impact and Clinical Outcomes

edited by Amparo García-Tejedor

submission deadline 30 Nov 2026 | 3 articles | Viewed by 3982 | Submission Open

Keywords: neoadjuvant chemotherapy; radiotherapy; breast cancer; surgical outcomes; tumor downstaging; personalized therapy; breast-conserving surgery; mastectomy; clinical outcomes

(This special issue belongs to the Section Cancer Therapy)

Primary Central Nervous System Lymphoma: A Challenging Disease

edited by

Roser Velasco

submission deadline 30 Nov 2026 | 2 articles | Viewed by 3721 | Submission Open

Keywords: primary central nervous system lymphoma (PCNSL); diffuse large B cell lymphoma (DLBCL); advanced imaging; novel therapies; prognostic markers

Recent Advances in the Understanding of Myelodysplastic Syndrome and Acute Myeloid Leukemia (2nd Edition)

edited by

Ioannis Mitroulis

, Konstantinos Liapis and

Eleni Gavriilaki

submission deadline 30 Nov 2026 | 1 articles | Viewed by 3555 | Submission Open

Keywords: myelodysplastic syndrome; acute myeloid leukemia; bone marrow micro-environment; targeted therapies; hematopoietic stem cell; leukemic stem cell; hematopoietic stem cell transplantation

(This special issue belongs to the Section Cancer Therapy)

T-Cell Lymphoma: From Diagnosis to Treatment

edited by Lubomir Sokol and Yumeng Zhang

submission deadline 30 Nov 2026 | 2 articles | Viewed by 3552 | Submission Open

Keywords: cutaneous T-cell lymphomas (CTCLs); peripheral T-cell lymphomas (PTCLs); Sezary syndrome (SS); mycosis fungoides (MF); genetic; epigenetic; therapeutic strategies

Hepatocellular Carcinoma Progression and Metastasis

edited by

Ching-Sheng Hsu

submission deadline 30 Nov 2026 | 1 articles | Viewed by 3354 | Submission Open

Keywords: hepatocellular carcinoma; tumor progression; metastasis; liver cancer; angiogenesis; epithelial–mesenchymal transition; tumor microenvironment; molecular pathways; biomarkers; targeted therapy; systemic therapy

(This special issue belongs to the Section Cancer Metastasis)

Pathology and Treatment of Triple-Negative Breast Cancer (2nd Edition)

edited by

Ramadevi Subramani

submission deadline 30 Nov 2026 | 3 articles | Viewed by 3307 | Submission Open

Keywords: triple-negative breast cancer (TNBC); molecular profiling; tumor microenvironment; targeted therapy; novel biomarkers

IBD-Associated Cancer

edited by Takayuki Ogino

submission deadline 30 Nov 2026 | 2 articles | Viewed by 3251 | Submission Open

Keywords: IBD-associated cancer; Crohn’s disease; ulcerative colitis; colorectal cancer; small bowel cancer; chemotherapy; radiotherapy

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

The Role of Human Papillomavirus (HPV) in Cancers: Epidemiology, Molecular Biology, and Advancements in Detection Methods

edited by

Peter C. Angeletti

submission deadline 30 Nov 2026 | 3 articles | Viewed by 3125 | Submission Open

Keywords: human papillomavirus (HPV); cancer; HPV-related cancer; epidemiology; oncogenesis; molecular mechanisms; diagnostic technologies; epidemiological trends; risk factors; HPV-associated cancers; molecular pathways; cellular pathways; biomarkers; diagnostic tools; immune response; host–pathogen interaction

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Displaying special issue 301-350 on page 7 of 22.

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