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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Innovations in Active Surveillance Management of Early Prostate Cancer

edited by

Vincent J. Gnanapragasam

submission deadline 8 Aug 2026 | 1 articles | Viewed by 1006 | Submission Open

Keywords: prostate cancer; risk stratification; active surveillance; predictive markers; personalized management; imaging; biomarkers; clinical pathways; patient outcomes; standardizing care; attrition; cohort studies

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Targeted Therapies in Sarcomas: Overcoming Resistance and Improving Outcomes

edited by

Varun Monga

and Mohammed M. Milhem

submission deadline 8 Aug 2026 | Viewed by 92 | Submission Open

Keywords: sarcoma; targeted therapy; resistance mechanisms; combination therapy; biomarkers; precision oncology; translational research; clinical trials

(This special issue belongs to the Section Tumor Microenvironment)

Clinical Surgery for Hepato-Pancreato-Biliary (HPB) Cancer

edited by

Gennaro Nappo

and

Michele Pagnanelli

submission deadline 10 Aug 2026 | 10 articles | Viewed by 16216 | Submission Open

Keywords: pancreatic malignancies; HPB malignancies; pancreatic ductal adenocarcinoma; liver cholangiocarcinoma; HPB surgery; liver resection; pancreatic resection

(This special issue belongs to the Section Cancer Therapy)

Near-Infrared Photoimmunotherapy for Cancer Treatment: 2nd Edition

edited by

Hisataka Kobayashi

submission deadline 10 Aug 2026 | Viewed by 339 | Submission Open

Keywords: NIR-PIT; phototherapy; monoclonal antibody; imaging biomarker; immunotherapy

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Bridging Translational and Clinical Oncology in Gastrointestinal Cancers: Molecular Mechanisms to Therapeutic Advances

edited by

Stavros Papadakos

Ioannis Katsaros

and

Stamatios E. Theocharis

submission deadline 10 Aug 2026 | Viewed by 143 | Submission Open

Keywords: gastrointestinal cancers; translational oncology; molecular mechanisms; biomarkers; immunotherapy; radiomics; precision medicine; therapeutic advances

(This special issue belongs to the Section Methods and Technologies Development)

The Tumorigenesis Mechanism of Breast Cancer

edited by Swayam Prabha

submission deadline 10 Aug 2026 | Viewed by 87 | Submission Open

Keywords: breast cancer; tumor microenvironment; myeloid-derived suppressor cells; immune evasion; premetastatic niche; epithelial– mesenchymal transition; PI3K/AKT/mTOR; MAPK/ERK; Wnt/β -catenin; BRCA1/2; TP53; estrogen signaling; targeted therapy; nanomedicine; biologics; precision oncology; translational research

(This special issue belongs to the Section Molecular Cancer Biology)

Research on Clinical Treatment of Mesothelioma: 2nd Edition

edited by

Giulia M. Stella

submission deadline 10 Aug 2026 | Viewed by 68 | Submission Open

Keywords: pleural mesothelioma; targeted therapy; local treatments; radiomics; genetic traits; occupational health; asbestos exposure

(This special issue belongs to the Section Clinical Research of Cancer)

Cytoreduction in Gynecologic Oncology

edited by Sabrina Piedimonte

submission deadline 14 Aug 2026 | Viewed by 14 | Submission Open

Keywords: cytoreduction; ovarian cancer; endometrial cancer; minimally invasive surgery; AI

(This special issue belongs to the Section Cancer Therapy)

Recent Updates and Future Perspectives on Anti-Cancer Agents

edited by

Santosh Kumar Singh

submission deadline 15 Aug 2026 | 2 articles | Viewed by 3018 | Submission Open

Keywords: cancer; anti-cancer agents; targeted therapy; drug resistance; therapeutic agents; natural compounds; combination therapy; nanotherapy; translational therapy; immunotherapy

(This special issue belongs to the Section Cancer Drug Development)

Rare Genitourinary Cancers

edited by

Luis G Medina

and

Philippe E. Spiess

submission deadline 15 Aug 2026 | Viewed by 172 | Submission Open

Keywords: rare genitourinary tumors; penile cancer; testicular cancer; urethral cancer; adrenal cancer; variant histology; upper tract urothelial carcinoma; extramammary Paget’ s disease; urologic oncology; rare cancers

(This special issue belongs to the Section Clinical Research of Cancer)

Immunotherapy for Hematologic Malignancies

edited by Rajesh Ramakrishnan Nair

submission deadline 15 Aug 2026 | Viewed by 141 | Submission Open

Keywords: immune evasion; immunotherapy; CAR-T cell therapy; BiTEs; immunomodulators; checkpoint; inhibitors; bone marrow microenvironment; refractory/relapsed; drug resistance; gene editing

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Clinical Applications of Advanced MRI Technologies for Cancers

edited by

Nicolò Cardobi

submission deadline 15 Aug 2026 | Viewed by 109 | Submission Open

Keywords: advanced MRI techniques; multiparametric imaging; quantitative biomarkers; artificial intelligence; treatment response assessment; precision oncology; radiomics; cancer diagnosis; functional imaging; molecular imaging

(This special issue belongs to the Section Methods and Technologies Development)

Cancer and Solid Organ Transplantation

edited by

Georgios Tsoulfas

submission deadline 15 Aug 2026 | Viewed by 28 | Submission Open

Keywords: post-transplant malignancy; transplant oncology; liver transplantation; multidisciplinary care; artificial intelligence; precision medicine; immunosuppression; transplant immunology; cancer immunology; cancer diagnosis

(This special issue belongs to the Section Transplant Oncology)

Advances in Immunotherapy for Acute Myeloid Leukemia

edited by

Pau Montesinos

submission deadline 15 Aug 2026 | Viewed by 21 | Submission Open

Keywords: acute myeloid leukemia; immunotherapy; immune response; T-cell; cellular therapies; immune checkpoint inhibitors; treatment

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Rare Cancers, Diagnostic Challenges and Personalized Therapeutic Approaches in the 21st Century (2nd Edition)

edited by

Jason Roszik

submission deadline 20 Aug 2026 | 2 articles | Viewed by 2714 | Submission Open

Keywords: rare cancer; biology; diagnosis; classification; personalized therapeutics; markers

(This special issue belongs to the Section Cancer Therapy)

Advances in Clinical, Diagnostic and Neurosurgical Management in Pediatric Neuro-Oncology

edited by

John Ross Crawford

and Michael Levy

submission deadline 20 Aug 2026 | Viewed by 195 | Submission Open

Keywords: neuro-oncology; brain tumors; neuroradiology; proton therapy; pediatric; neurosurgery; treatment; chemotherapy; targeted agents; molecular subtypes; immunotherapy; late effects; radiation therapy

(This special issue belongs to the Section Pediatric Oncology)

Socio-Demographic Factors and Cancer Research: 2nd Edition

edited by

Mitchell S. Fourman

and Amanda N. Goldin

submission deadline 20 Aug 2026 | Viewed by 151 | Submission Open

Keywords: socio-economic disparity; cancer delivery; cancer survival; metastatic cancer; culture-specific cancer outcomes; AI; machine learning

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Advances in Surgery for Endocrine Cancers

edited by Michael Bouvet and Eren Berber

submission deadline 20 Aug 2026 | Viewed by 89 | Submission Open

Keywords: thyroid cancer; thyroid surgery; hyperparathyroidism; adrenal tumors; adrenal surgery; pancreatic neuroendocrine tumors; fluorescence guided surgery; intraoperative imaging; surgical navigation; technological innovation

(This special issue belongs to the Section Methods and Technologies Development)

Pain and Palliative Care in Patients with Cancers

edited by

Arpad Szallasi

and

Anna Horváth

submission deadline 20 Aug 2026 | Viewed by 84 | Submission Open

Keywords: cancer pain; palliative care; opioid tolerance

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Multidisciplinary Strategies in Challenging Neuro-Oncological Surgery

edited by

Eiichi Ishikawa

submission deadline 20 Aug 2026 | Viewed by 38 | Submission Open

Keywords: neuro-oncology; surgery; awake craniotomy; intraoperative MRI; MRI navigation system; intraoperative photodynamic diagnosis/therapy; intraoperative pathological diagnosis

(This special issue belongs to the Section Clinical Research of Cancer)

Diagnostic Biomarkers in Cancers Study

edited by Zejuan Li and

Xin Yi

submission deadline 21 Aug 2026 | 4 articles | Viewed by 8067 | Submission Open

Keywords: cancer; diagnostics; biomarker

(This special issue belongs to the Section Cancer Biomarkers)

Contemporary Diagnosis and Management of Prostate Cancer (2nd Edition)

edited by Thomas Jang

submission deadline 22 Aug 2026 | 1 articles | Viewed by 1708 | Submission Open

Keywords: prostate cancer; diagnosis; management; radical prostatectomy; biomarkers

(This special issue belongs to the Section Cancer Therapy)

Clinical Studies of Colorectal Cancer Surgery

edited by

Konstantinos Perivoliotis

and Ioannis Baloyiannis

submission deadline 25 Aug 2026 | Viewed by 53 | Submission Open

Keywords: colon; rectal; cancer; clinical; trials; evidence; open; laparoscopic; robotic; surgery

(This special issue belongs to the Section Clinical Research of Cancer)

Contemporary Advances and Challenges in Multimodal Management of Gastric Cancer

edited by

Karol Rawicz-Pruszyński

and Zuzanna Pelc

submission deadline 25 Aug 2026 | Viewed by 26 | Submission Open

Keywords: gastric cancer; multimodal therapy; perioperative chemotherapy; immunotherapy; minimally invasive surgery/robotic gastrectomy; surgical escalation and de-escalation; conversion surgery; patient selection/prognostic factors; biomarkers (her2; pd-l1; msi; ctdna); perioperative nutrition/eras

(This special issue belongs to the Section Cancer Therapy)

Modern Approach to Oral Cancer

edited by

Maria Maddalena Marrapodi

and

Giuseppe Minervini

submission deadline 30 Aug 2026 | 11 articles | Viewed by 49546 | Submission Open

Keywords: oral cancer; neoplasm; oral surgery oncogenesis; dentistry oral health

(This special issue belongs to the Section Cancer Therapy)

Long-Term Health Outcomes and Quality of Life in Survivors of Childhood Cancer

edited by

Esteban Orenes-Piñero

submission deadline 30 Aug 2026 | 2 articles | Viewed by 1392 | Submission Open

Keywords: acute lymphoblastic leukemia; brain tumors; childhood cancer survivors; pollutants; environment; quality of life; nutrition; chemotherapy; air and water purification

(This special issue belongs to the Section Pediatric Oncology)

Pathology of Acute Myeloid Leukemia (AML)

edited by Olga K. Weinberg

submission deadline 30 Aug 2026 | Viewed by 1282 | Submission Open

(This special issue belongs to the Section Cancer Pathophysiology)

Pathology of Gynecological Cancers (2nd Edition)

edited by

Mohamed Desouki

submission deadline 30 Aug 2026 | Viewed by 272 | Submission Open

Keywords: endometrial cancer; ovarian cancer; vulvar cancer; cervical cancer; vaginal cancer

(This special issue belongs to the Section Cancer Pathophysiology)

Robotic and Laparoscopic Surgery in Colorectal Cancer: Current Trends and Future Perspectives

edited by

Felix Aigner

, Quentin Denost and Barbara Noiret

submission deadline 30 Aug 2026 | Viewed by 165 | Submission Open

Keywords: robotic surgery; laparoscopic surgery; colorectal cancer; minimally invasive surgery; comparative outcomes (perioperative; oncologic; functional); conversion rates; open surgery; learning curve and surgical training; cost‐effectiveness and health economics; technological innovations (e.g.; AI; imaging; instrumentation); quality of life and long‐term patient‐reported outcomes

(This special issue belongs to the Section Cancer Therapy)

Proteometabolomics in Cancer

edited by

Samir M. Hanash

and

Johannes Fahrmann

submission deadline 30 Aug 2026 | Viewed by 163 | Submission Open

Keywords: proteomics; metabolomics; cancer biology; tumor microenvironment; biomarkers; therapeutics

(This special issue belongs to the Section Molecular Cancer Biology)

Neoantigen Vaccines for Cancer Therapy

edited by Takashi Morisaki

submission deadline 30 Aug 2026 | Viewed by 126 | Submission Open

Keywords: neoantigens; vaccine; dendritic cells; cancer; immunotherapy; priming; CTL; helper T cells

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Tumor Suppressor and Targeted Therapy in Hepatocellular Carcinoma: From Diagnosis to Treatment (2nd Edition)

edited by

Ching-Sheng Hsu

Po-Heng Chuang

and I-Cheng Lee

submission deadline 30 Aug 2026 | Viewed by 110 | Submission Open

Keywords: tumor suppressor; targeted therapy; hepatocellular carcinoma

(This special issue belongs to the Section Tumor Microenvironment)

Challenges and Opportunities in Developing Therapies for Drug Resistance and Other Malignancies

edited by

Erzsébet Mernyák

submission deadline 30 Aug 2026 | Viewed by 19 | Submission Open

Keywords: cancer; chemotherapy; multidrug resistance; innovative therapy

Research on Fluorescence-Guided Surgery in Cancer Treatment (2nd Edition)

edited by

Julius Höhne

submission deadline 30 Aug 2026 | Viewed by 13 | Submission Open

Keywords: fluorescence-guided surgery; fluorescent agents; tumor fluorescence; tumor margin detection; residual tumor assessment; glioma surgery; fluorescein sodium; 5-aminolevulinic acid; confocal endomicroscopy; Raman spectroscopy

(This special issue belongs to the Section Cancer Therapy)

Gastrointestinal Malignancy: Epidemiology and Risk Factors

edited by Patrick Okolo and Chengu Niu

submission deadline 31 Aug 2026 | 8 articles | Viewed by 35100 | Submission Open

Keywords: gastrointestinal cancer; epidemiology; risk factors; molecular markers; genetic factors; therapeutic advancements; prevention strategies; public health; interdisciplinary approaches; clinical impact

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Advancements in “Cancer Biomarkers” for 2025–2026

edited by

Maxim V. Berezovski

submission deadline 31 Aug 2026 | 13 articles | Viewed by 19742 | Submission Open

Keywords: RNA biomarkers; miRNA biomarkers; DNA biomarkers; cell-free DNA (cfDNA); protein biomarkers; metabolomic biomarkers; mutational biomarkers; circulating tumor cells (CTCs); tumor-derived extracellular vesicle (tEV) biomarkers; cellular biomarkers; imaging biomarkers; clinical biomarkers; biomarkers of drug response; biomarkers of genetic predisposition to cancer; epigenetic biomarkers; biomarkers of cancer outcomes; mass spectrometry; next-generation sequencing (NGS); flow cytometry; positron emission tomography (PET); computed tomography (CT); magnetic resonance imaging (MRI); X-rays; ultrasound; electrocardiography (ECG/EKG); endoscopy; biopsy; pulmonary function tests (PFTs); histopathology; cytopathology; immunohistochemistry (IHC); in situ hybridization (ISH); fluorescence in situ hybridization (FISH); liquid biopsy; electron microscopy; digital pathology and image analysis

(This special issue belongs to the Section Cancer Biomarkers)

Advancing Horizons in Colorectal Surgery: Innovative Approaches and Outcomes

edited by Petros I. Bangeas and Vasileios N. Papadopoulos

submission deadline 31 Aug 2026 | 4 articles | Viewed by 18404 | Submission Open

Keywords: colorectal surgery; postoperative pain; surgical site infections; anastomotic leaks; minimally invasive techniques; robotic surgery

(This special issue belongs to the Section Cancer Therapy)

Feature Review Paper Special Issue in Section Molecular Cancer Biology

edited by

Donat Kögel

submission deadline 31 Aug 2026 | 3 articles | Viewed by 9835 | Submission Open

Keywords: molecular biology; cell biology; cancer; tumor; cancer cell

(This special issue belongs to the Section Molecular Cancer Biology)

Prevention, Early Detection, and Surgical Oncology in Hepatocellular Carcinoma, Pancreatic Cancer, and Gastrointestinal Cancer

edited by

Mingyao Chen

and

Kuang-Chun Hu

submission deadline 31 Aug 2026 | 4 articles | Viewed by 6214 | Submission Open

Keywords: early image detection in cancer; biomarker of cancer; surgical treatment; gastrointestinal cancer

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Cancer Stem Cells: The Origin of Tumor Relapse and Metastasis

edited by

Ming Tan

and

Evgeniy V. Denisov

submission deadline 31 Aug 2026 | 3 articles | Viewed by 5401 | Submission Open

Keywords: metastasis; cancer stem cell; tumor microenvironment; tumor heterogeneity; plasticity; immune evasion; therapeutic resistance

(This special issue belongs to the Section Molecular Cancer Biology)

The Genetic Analysis and Clinical Therapy in Lung Cancer: 2nd Edition

edited by

Francesca Colombo

and Frullanti Elisa

submission deadline 31 Aug 2026 | 1 articles | Viewed by 4480 | Submission Open

Keywords: lung cancer; biomarkers; genetic variants; innovative technologies; targeted therapy; immunotherapy; personalized therapy; survival; liquid biopsy pharmacogenomics

(This special issue belongs to the Section Cancer Therapy)

Tumor Microenvironment in Cancer Therapies: Supportive or Hostile?

edited by

Constantin N. Baxevanis

submission deadline 31 Aug 2026 | 1 articles | Viewed by 1257 | Submission Open

Keywords: tumor microenvironment; protumor effects; antitumor effects; immune cells; stromal cells; extracellular matrix; cancer therapies

(This special issue belongs to the Section Tumor Microenvironment)

CAR T-Cell Therapy and Multiple Myeloma

edited by Jo Caers

submission deadline 31 Aug 2026 | 1 articles | Viewed by 1037 | Submission Open

Keywords: multiple myeloma; CAR-T immunotherapy; toxicity; efficacy; tumor models; safety

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

New Advances and Approaches in Thyroid Cancer

edited by

Beatriz Febrero

and José Manuel Rodríguez

submission deadline 31 Aug 2026 | 1 articles | Viewed by 848 | Submission Open

Keywords: thyroid cancer; medullary thyroid cancer; papillary thyroid cancer; follicular thyroid cancer; poorly differentiated thyroid tumours; novel approaches; prognostic biomarkers; risk stratification

(This special issue belongs to the Section Cancer Therapy)

Emergencies in Gastrointestinal Surgical Oncology

edited by

Fausto Rosa

Carlo Alberto Schena

and

Nicola De'Angelis

submission deadline 31 Aug 2026 | Viewed by 574 | Submission Open

Keywords: surgical oncology; emergencies; emergency surgery; acute care surgery; palliation; futility in surgery

(This special issue belongs to the Section Clinical Research of Cancer)

Hereditary Cancer: State of the Art

edited by Joanne Ngeow, Jianbang Chiang and

Rashid N. Lui

submission deadline 31 Aug 2026 | Viewed by 215 | Submission Open

Keywords: hereditary cancer syndromes; inherited cancers; cancer genetics and genomics; germline variants; surveillance

(This special issue belongs to the Section Cancer Pathophysiology)

Hypoxia-Targeting Strategies to Improve Cancer Therapy Outcomes

edited by Roben Gieling and Ayse Latif

submission deadline 31 Aug 2026 | 1 articles | Viewed by 166 | Submission Open

Keywords: tumor hypoxia; cancer therapy resistance; hypoxia-targeted therapy; hypoxia-inducible factors (HIFs); hypoxia-activated prodrugs; oxygen-modifying agents; combination therapy; precision drug delivery; tumor microenvironment; translational cancer research

(This special issue belongs to the Section Cancer Therapy)

CAR T Cell Therapy in Cancer: Progress and Challenges Across Solid and Hematologic Malignancies

edited by John F. Marshall and Lauren C. Cutmore

submission deadline 31 Aug 2026 | Viewed by 133 | Submission Open

Keywords: CAR-T cell therapy; adoptive cell therapy; immunotherapy; antigen escape; solid tumor; hematologic malignancies

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Acute Myeloid Leukemia in Adults (2nd Edition)

edited by

Theodoros Karantanos

submission deadline 31 Aug 2026 | Viewed by 124 | Submission Open

Keywords: acute myeloid leukemia; molecular biology; treatment landscape; resistance mechanisms

(This special issue belongs to the Section Clinical Research of Cancer)

Human Carcinogens—Chemical Agents, Occupational Exposure and Health Impact

edited by Jun-Pyo Myong

submission deadline 31 Aug 2026 | Viewed by 121 | Submission Open

Keywords: occupational exposure; chemical carcinogens; risk assessment; epidemiology; biomarkers; exposure assessment; preventive strategies; workplace safety; occupational health; regulatory measures

(This special issue belongs to the Section Infectious Agents and Cancer)

Displaying special issue 1001-1050 on page 21 of 25.

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