Advancing Horizons in Colorectal Surgery: Innovative Approaches and Outcomes

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".

Deadline for manuscript submissions: 31 August 2025 | Viewed by 990

Special Issue Editors

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Guest Editor
The First University Surgery of Papageorgiou, Aristotle University of Thessaloniki, Thessaloniki, Greece
Interests: colorectal cancer; computed tomography; surgery

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Guest Editor
Director of Aristotle University Surgery Department, Papageorgiou Hospital, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece
Interests: gastrointestinal; breast; biliary
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Special Issue Information

Dear Colleagues,

Colorectal surgery is a rapidly evolving field, with new techniques and innovations being developed at a rapid pace. As surgeons working in the field of colorectal surgery, we have recognized the need for a dedicated Special Issue that focuses on the latest advancements in this area.

Our experience in the field has shown us that there is a great deal of interest among practitioners in learning about new techniques and innovations in colorectal surgery, and we believe that a Special Issue could fill this need.

The proposed Special Issue in Cancers would be devoted to publishing cutting-edge research and clinical studies related to colorectal surgery innovations and new techniques. It would provide a platform for surgeons and researchers to disseminate their findings, share best practices, and foster collaboration within the field.

This proposed Special Issue would cover a wide range of topics, including new surgical techniques, technological advancements, clinical outcomes, and advances in the understanding and management of colorectal diseases.

One of the key focus areas of this Special Issue would be on the era period of colorectal surgery, which refers to the early postoperative period following colorectal surgery. This is a critical time for patients, as they are at risk for complications such as postoperative pain, surgical site infections, and anastomotic leaks. By focusing on this specific period, this Special Issue would provide practical insights and evidence-based guidance to help surgeons optimize patient outcomes and minimize complications.

In addition to the era period, this Special Issue would also cover other important aspects of colorectal surgery, such as minimally invasive techniques, robotic surgery, and advances in imaging and diagnostic tools. We believe that by bringing together the latest research and clinical experiences in these areas, this Special Issue could serve as a valuable resource for surgeons and researchers working in the field.

In terms of the types of content that this Special Issue would publish, we envision that it would include original research articles and review articles. It would also welcome submissions from multidisciplinary teams, as we believe that collaboration between surgeons, oncologists, gastroenterologists, and other specialists is essential for advancing the field of colorectal surgery. Another important aspect of this proposed Special Issue would be its commitment to fostering a global perspective on colorectal surgery.

We recognize that practices and challenges in colorectal surgery can vary widely across different regions and healthcare systems. As such, this Special Issue would seek to publish studies and perspectives from a diverse range of geographic locations, in order to facilitate the exchange of knowledge and experiences on a global scale.

In conclusion, we believe that there is a clear need for a Special Issue dedicated to colorectal surgery innovations and new techniques. Our proposed Special Issue would provide a valuable platform for disseminating the latest research and clinical experiences in the field, with a particular focus on the era period and other critical aspects of colorectal surgery.

In conclusion, we have highlighted some sectors of colorectal surgery in order to emphasize the relevant innovative areas:

  1. Minimally Invasive Surgery (MIS);
  2. Robotic surgery;
  3. TAMIS Surgery;
  4. TaTME procedures;
  6. Single-Incision Laparoscopic Surgery (SILS);
  7. Colorectal Ccncer screening and advanced polypectomy techniques;
  8. Endoluminar Surgery;
  9. Biofeedback and neuromodulation for patients experiencing defecatory disorders;
  10. Regenerative medicine;
  11. New imaging technologies (3D Printing, nanotechnology, artificial intelligence);
  12. Gut microbiota, nutrition, and gut barrier dysfunction.

We are confident that this Special Issue would be well received by the colorectal surgery community, and we are excited about the potential impact it could have on advancing patient care and surgical practice in this rapidly evolving field.

Dr. Petros I. Bangeas
Prof. Dr. Vasileios N. Papadopoulos
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • colorectal surgery
  • postoperative pain
  • surgical site infections
  • anastomotic leaks
  • minimally invasive techniques
  • robotic surgery

Published Papers (1 paper)

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26 pages, 1756 KiB  
Current and Future Trends of Colorectal Cancer Treatment: Exploring Advances in Immunotherapy
by Taxiarchis Konstantinos Nikolouzakis, Emmanuel Chrysos, Anca Oana Docea, Persefoni Fragkiadaki, John Souglakos, John Tsiaoussis and Aristidis Tsatsakis
Cancers 2024, 16(11), 1995; - 24 May 2024
Viewed by 314
Cancer of the colon and rectum (CRC) has been identified among the three most prevalent types of cancer and cancer-related deaths for both sexes. Even though significant progress in surgical and chemotherapeutic techniques has markedly improved disease-free and overall survival rates in contrast [...] Read more.
Cancer of the colon and rectum (CRC) has been identified among the three most prevalent types of cancer and cancer-related deaths for both sexes. Even though significant progress in surgical and chemotherapeutic techniques has markedly improved disease-free and overall survival rates in contrast to those three decades ago, recent years have seen a stagnation in these improvements. This underscores the need for new therapies aiming to augment patient outcomes. A number of emerging strategies, such as immune checkpoint inhibitors (ICIs) and adoptive cell therapy (ACT), have exhibited promising outcomes not only in preclinical but also in clinical settings. Additionally, a thorough appreciation of the underlying biology has expanded the scope of research into potential therapeutic interventions. For instance, the pivotal role of altered telomere length in early CRC carcinogenesis, leading to chromosomal instability and telomere dysfunction, presents a promising avenue for future treatments. Thus, this review explores the advancements in CRC immunotherapy and telomere-targeted therapies, examining potential synergies and how these novel treatment modalities intersect to potentially enhance each other’s efficacy, paving the way for promising future therapeutic advancements. Full article
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