Rare Skin Cancers: Recent Advances in Classification and Management

Dear Colleagues,

Rare skin neoplasms include various tumors ranging from low grade proliferations with local infiltration to high grade tumors with metastatic potential. They include rare epithelial tumors such as Merkel cell carcinoma, adnexal tumors and advanced basal cell carcinoma, rare melanocytic proliferations such as melanocytomas and atypical Spitz tumors, lymphoid neoplasms (T- and B-cell primary cutaneous lymphoproliferations), and several mesenchymal proliferations such as Kaposi’s sarcoma, dermatofibrosarcoma protuberans, angiosarcoma or pleomorphic dermal sarcoma.

New immunohistochemical and molecular discoveries have considerably improved the diagnosis, pathogenesis and phylogenetic comprehension of these tumors with significant epidemiological, theranostic and therapeutic consequences. Many efficient therapies (PD1 blockade, targeted therapies) have emerged in the management of many cancers, some of them being currently tested or already approved in rare skin tumors.

Prof. Céleste Lebbé
Prof. Maxime Battistella
Guest Editors

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