Molecular Advances in Diffuse Large B-Cell Lymphoma

Dear Colleagues,

Diffuse large B-cell lymphomas are heterogeneous aggressive lymphomas whose molecular background is still poorly understood. They are biologically and clinically different based on age (children, adults, elderly) of onset, place of development (nodal vs. extranodal), viral relationship, and immunosurveillance. Moreover, genetic subgroups have also been identified, such as high grade B-cell lymphomas with double or triple MYC/BCL2/BCL6 gene rearrangements, 11q Burkitt-like lymphoma, IRF4 translocated, or ALK translocated lymphomas, among others. We are proposing an extended review of new molecular advances in diffuse large B-cell lymphomas, taking into account all these previous features. Moreover, we highlight the existence of new approaches for high-grade B-cell lymphoma identification.

Prof. Dr. Socorro María Rodríguez-Pinilla
Dr. Arantza Onaindia
Dr. Paola A Chabay
Dr. Fina Climent
Guest Editors

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