Novel Biomarkers and Dose-Response Modifiers in Radiation Oncology and Nuclear Medicine: Molecular Insights for Personalized Therapy and Precision Medicine

A special issue of Cancers (ISSN 2072-6694).

Deadline for manuscript submissions: 31 March 2026

Special Issue Editors


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Guest Editor
1. Radiation Oncology, University Hospital Essen, University Duisburg, Strahlenklinik, Hufeland Street 55, 45122 Essen, Germany
2. EBG MedAustron GmbH, Marie Curie-Straße 5A-2700 Wiener Neustadt, Austria
3. Neutron Therapy Research Center, Okayama University, Okayama 700-8530, Japan
4. German Society for Boron Neutron Capture Therapy, 45122 Essen, Germany
Interests: radiation oncology; hadron therapy; boron neutron capture therapy (BNCT); neutrons; high-LET radiation; radiation biology; eye tumors; ophthalmic oncology
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E-Mail Website
Guest Editor
Department of Radiation Therapy and Radiation Oncology, University Hospital Würzburg, Josef-Schneider-Str. 11, 97080 Würzburg, Germany
Interests: radiosurgery; stereotactic radiotherapy; advanced imaging and biological response modifiers to develop adaptive strategies in high-precision radiotherapy; personalized medicine; palliative treatments
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Radiation oncology and nuclear medicine are placing increasing importance on testing and employing biomarkers to reveal key information about specific cancers and how they respond to particular therapies. Another pivotal issue is the manner in which biological molecules modify individual responses to ionizing radiation. Innovative targeting based on molecules that increase the local effects of radiation is a further aspect to be considered. The objective of this Special Issue is to furnish a comprehensive overview of contemporary methodologies employed for predicting outcomes and modifying responses to external radiotherapy, brachytherapy, and internal radiotherapy in the domain of nuclear medicine. A particular focus of this Special Issue is to provide an overview of the molecular mechanisms intended for personalized approaches in the application of ionizing radiation for cancer treatments.

Prof. Dr. Wolfgang Sauerwein
Prof. Dr. Andrea Wittig
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Prof. Dr. Wolfgang Sauerwein
Prof. Dr. Andrea Wittig
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • targeted therapies
  • predictive essays
  • radiosensitizers
  • radioprotectors
  • theranostics
  • BNCT
  • alpha-immunotherapy
  • biological response modifiers
  • biomarkers

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Published Papers

This special issue is now open for submission.
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