Neuroendocrine Tumors: From Diagnosis to Therapy
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".
Deadline for manuscript submissions: closed (20 April 2025) | Viewed by 16381
Special Issue Editors
Interests: imaging; oncology; CT; MRI; artificial intelligence; radiomics; response to therapy
Special Issues, Collections and Topics in MDPI journals
2. Department of Medical, Surgical Sciences and Translational Medicine, Sapienza University of Rome, 00189 Rome, Italy
Interests: neuroendocrine tumors; gastrointestinal disorders; pancreatic diseases; malnutrition
Special Issues, Collections and Topics in MDPI journals
Interests: nuclear medicine; PET/CT; response to therapy; PRRT
Interests: imaging; oncology; CT; MRI; artificial intelligence; radiomics; response to therapy
Special Issue Information
Dear Colleagues,
Neuroendocrine neoplasms (NENs) are considered rare tumors with a wide spectrum of behaviors, manly indolent, but are highly dependent on the presence of high-risk clinical features (such as metastatic disease, grading, ki67, the expression of somatostatin receptors, and primary sites). Diagnoses, using a dual morphological and functional approach in NENs, are based on histology and imaging.
However, these conventional evaluations can have some intrinsic drawbacks, from the limited tissue sampling, in the case of tumor biopsy, to the bias linked to the subjective assessment of medical images. Furthermore, based on the assessment of response to therapy, the morphological RECIST 1.1 criteria could be reductive and not appropriate, especially in the case of target therapy.
In this context, quantitative imaging has acquired relevance as a supporting tool for clinicians in order to overcome the limits associated with the conventional approach, especially in prediction prognosis and in response to therapy. Thus, to outline a structured therapeutic path, one of the future landscapes of NEN management may be the integration of quantitative imaging with conventional evaluations.
This Special Issue will highlight the main strengths and limitations in the management of NENs, from the diagnosis to the response to therapy, and will investigate the emerging role of quantitative biomarkers.
Dr. Damiano Caruso
Prof. Dr. Francesco Panzuto
Dr. Daniela Prosperi
Dr. Michela Polici
Guest Editors
Manuscript Submission Information
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Keywords
- neuroendocrine neoplasms
- CT
- MR
- PET/CT
- target therapy
- quantitative biomarkers
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