Personalized Pharmacological Treatment in Schizophrenia: The Role of New Antipsychotics

Dear Colleagues,

Schizophrenia is a severe mental illness associated with disability and with a significant reduction in quality of life and with large economic costs related to disability and the impact on work, family, and social functioning.

Pharmacological therapy represents the cornerstone for a successful intervention. Antipsychotic drugs differ in terms of efficacy and tolerability for individual patients and should be administered in conjunction with appropriate psychosocial and rehabilitation interventions. It is therefore necessary to identify and know the techniques of personalization of the therapy, which take into account clinical dimensions, such as negative and cognitive symptoms, and other variables, such as tolerability, adherence, psychosocial functioning, and patient preference.

This Special Issue will provide an update on pharmacological treatments for schizophrenia, from the acute phase to the maintenance and rehabilitation phase, and on the best strategies to provide each patient with a therapy that is based on the latest scientific evidence and, at the same time, adapted to the needs of individual people.

Particular attention will be paid to the need to find a favorable balance between efficacy, tolerability, and adherence to treatment.

Prof. Dr. Stefano Barlati
Guest Editor

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