Special Issues

Biomolecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

Section
Search by Title/Keyword
 
Order results
Display
Results per page
Nutritional Intervention and Molecular Mechanism of Liver Cancer
edited by and Yohei Shirakami
submission deadline 31 Dec 2025 | Submission Open
Keywords: liver cancer; nutrient signaling; inflammation and metabolism; cancer stem cells; precision nutrition
(This special issue belongs to the Section Molecular Medicine)
Muscular Dystrophy: From Molecular Basis to Therapies: 2nd Edition submission deadline 15 Jan 2026 | Viewed by 206 | Submission Open
Keywords: muscular dystrophies; muscle regeneration; extracellular matrix; satellite cells; therapeutic approaches; animal models; clinical trials
Molecular Pathology, Diagnostics and Therapeutics of Retinal Diseases: 2nd Edition
edited by
submission deadline 15 Jan 2026 | Viewed by 198 | Submission Open
Keywords: retina; macula; macular edema; inflammatory mediators; optical coherence tomography; retinal imaging; biochemical marker; biomarker; pharmacological targeting
Updates on Mitochondria and Cancer submission deadline 15 Jan 2026 | Viewed by 109 | Submission Open
Keywords: mitochondrial dysfunction in cancer; mitochondrial metabolomics; mitochondria and cancer therapy; mitochondria and cancer drug resistance; prognostic/predictive mitochondrial markers in cancer tissues and body fluids
(This special issue belongs to the Section Biological Factors)
Inflammation and Immunity in Lung Disease
edited by
submission deadline 15 Jan 2026 | Viewed by 53 | Submission Open
Keywords: lung; infection; inflammation; host defense; cytokine release syndrome; genetic deficiency
(This special issue belongs to the Section Cellular Biochemistry)
Epigenetic Programming of Cellular States
edited by
submission deadline 15 Jan 2026 | Viewed by 21 | Submission Open
Keywords: iPSCs; stem cells; reprogramming; chromatin; epigenetics
Skeletal Muscle Homeostasis and Regeneration: 2nd Edition
edited by
submission deadline 15 Jan 2026 | Viewed by 20 | Submission Open
Keywords: skeletal muscle; homeostasis; regeneration; satellite cells; fiber type
(This special issue belongs to the Section Molecular Medicine)
Lipid Signaling in Neuroinflammation and Neurodegeneration
edited by
submission deadline 20 Jan 2026 | Viewed by 27 | Submission Open
Keywords: lipid signaling; neuroinflammation; neurodegeneration; sphingolipids; eicosanoids; phospholipids; endocannabinoids; lipid mediators; molecular mechanisms; brain health
Novel Mechanisms in Renal Blood Pressure Regulation: From Neuropeptides to Angiotensin II and Dopamine Receptors
edited by and
submission deadline 23 Jan 2026 | Viewed by 57 | Submission Open
Keywords: neuropeptides; dopamine; blood pressure; G protein-coupled receptors; oxidative stress kidney; vasculature; brain
Cellular Stress Responses in Oncogenesis and Metabolic Reprogramming
edited by
submission deadline 30 Jan 2026 | Viewed by 33 | Submission Open
Keywords: cellular stress response; metabolic reprogramming; oncogenesis; lipid metabolism; tumor adaptation; mitochondrial metabolism
(This special issue belongs to the Section Cellular Biochemistry)
Mitochondrial ROS in Health and Disease
edited by
submission deadline 31 Jan 2026 | 7 articles | Viewed by 15910 | Submission Open
Keywords: aging; apoptosis; respiratory chain; redox signaling; paclitaxel
(This special issue belongs to the Section Chemical Biology)
Inositol Phosphates in Health and Disease, 2nd Edition
edited by and
submission deadline 31 Jan 2026 | 6 articles | Viewed by 15006 | Submission Open
Keywords: inositol polyphosphates (IPs); IP6; inositol pyrophosphate (PP-Ips); signal transduction; energy metabolism; anticancer activity; PCOS; metabolic diseases; pathological calcification; neuropsychiatric disease
(This special issue belongs to the Section Molecular Medicine)
Harnessing Protein Design and Engineering for Therapeutic Applications
edited by Julia Shifman and Norman Metanis
submission deadline 31 Jan 2026 | 5 articles | Viewed by 12092 | Submission Open
Keywords: therapeutic peptides and proteins; protein design and engineering; chemical protein synthesis; chemoselective protein modification; posttranslational protein modification
(This special issue belongs to the Section Molecular Biophysics: Structure, Dynamics, and Function)
Molecular Mechanisms of Metabolic Regulation Used by G Protein-Coupled Receptors
edited by and Jason M. Conley
submission deadline 31 Jan 2026 | 3 articles | Viewed by 7317 | Submission Open
Keywords: diabetes; obesity; metabolism; GPCR; signaling
(This special issue belongs to the Section Molecular Biology)
Advances in Metabolites Produced by Microbiota submission deadline 31 Jan 2026 | 3 articles | Viewed by 7246 | Submission Open
Keywords: microbiota; metabolites; short-chain fatty acids; amino acids; vitamins
(This special issue belongs to the Section Cellular Biochemistry)
The Immune System and Allergies
edited by
submission deadline 31 Jan 2026 | 3 articles | Viewed by 7221 | Submission Open
Keywords: immune system; allergy; inflammation; hypersensitivity; immunology
(This special issue belongs to the Section Cellular Biochemistry)
Feature Papers in Cellular Biochemistry submission deadline 31 Jan 2026 | 6 articles | Viewed by 6888 | Submission Open
Keywords: cell signalling; cell death; intracellular trafficking (protein; lipids; cytoskeleton; etc.); host– pathogen interactions; extracellular vesicle biology; intercellular communication; autophagy; cellular metabolism; inter-organelle communication; membrane transport; mitochondrial dynamics and function; cell polarity
(This special issue belongs to the Section Cellular Biochemistry)
The Illumination of Biophysical Mechanisms by Hydrogen Exchange: A Themed Issue in Honor of Professor S. Walter Englander
edited by
submission deadline 31 Jan 2026 | 3 articles | Viewed by 6079 | Submission Open
Keywords: hydrogen exchange chemistry; HX– NMR; HX-MS; protein folding; allostery; protein binding; protein thermodynamics; protein biophysics; protein function
(This special issue belongs to the Section Molecular Biology)
Neurodevelopmental Disorders: Genetic Studies and Therapeutic Strategies
edited by and Bruno Bontempi
submission deadline 31 Jan 2026 | 1 articles | Viewed by 3742 | Submission Open
Keywords: mouse models; Autism Spectrum disorder; transgenic rodents; pharmacological treatments; gene-environment interactions; neurodevelopmental disorders; rare diseases
(This special issue belongs to the Section Molecular Genetics)
Retinal Diseases: Molecular Mechanisms and Therapies
edited by and Raquel Boia
submission deadline 31 Jan 2026 | 3 articles | Viewed by 3659 | Submission Open
Keywords: retinal diseases; molecular mechanisms; therapeutic strategies; vision impairment; gene therapy; retinal degeneration; neuroprotection; innovative treatments
(This special issue belongs to the Section Cellular Biochemistry)
Pharmacology of Cardiovascular Diseases
edited by , Alexandra Gyongyosi and
submission deadline 31 Jan 2026 | 2 articles | Viewed by 3146 | Submission Open
Keywords: cardioprotection autophagy; redox balance; heart faliure; cardiovascular pharmacotherapy
(This special issue belongs to the Section Molecular Medicine)
Molecular Advances in Rett Syndrome and Other Chromatin Related Disorders
edited by and Salvatore Fioriniello
submission deadline 31 Jan 2026 | 2 articles | Viewed by 3090 | Submission Open
Keywords: Rett syndrome and other chromatin disorders; epigenetic diseases; molecular alterations in Rett syndrome and other chromatin diseases; novel genes associated with chromatin disorders; MeCP2-mediated molecular mechanisms; roles of epigenetic modulators in chromatin-related diseases; preclinical studies for chromatin diseases; novel diagnostic; prognostic and therapeutic approaches for chromatin disorders
(This special issue belongs to the Section Molecular Medicine)
Natural Products and Their Derivatives with Antiviral Activity
edited by
submission deadline 31 Jan 2026 | 1 articles | Viewed by 855 | Submission Open
Keywords: natural products; synthetic antivirals; antiviral drugs; antiviral strategies; influenza; HBV; HIV; RSV; COVID-19; SARS-CoV-2
(This special issue belongs to the Section Natural and Bio-derived Molecules)
Developmental Biology of the Kidney: From Molecular Mechanisms to Congenital Disorders
edited by and Anita Racetin
submission deadline 31 Jan 2026 | 1 articles | Viewed by 700 | Submission Open
Keywords: kidney development; renal physiology; kidney disease; molecular mechanisms; cellular signaling; gene expression; biomarkers; renal pathophysiology; therapeutic targets
(This special issue belongs to the Section Molecular Medicine)
Pluripotent Stem Cells: From Basic Research to Therapeutic Applications submission deadline 31 Jan 2026 | Viewed by 319 | Submission Open
Keywords: pluripotent stem cells; embryonic stem cells; induced pluripotent stem cells; organoids; differentiation; regenerative medicine; disease modeling; cell therapy; therapeutic applications
(This special issue belongs to the Section Molecular Biology)
Inflammation Biology in Orthodontic Tooth Movement
edited by
submission deadline 31 Jan 2026 | Viewed by 292 | Submission Open
Keywords: orthodontic tooth movement; inflammation; cytokine; root resorption; accelerated orthodontic tooth movement; relapse
(This special issue belongs to the Section Biological Factors)
Cellular and Molecular Basis of Parasite Infection submission deadline 31 Jan 2026 | Viewed by 261 | Submission Open
Keywords: parasite infection; host– parasite interaction; cellular invasion; molecular mechanisms; immune evasion
(This special issue belongs to the Section Molecular Medicine)
Cellular and Molecular Mechanisms in Cardiopathy and Therapeutic Strategies
edited by Ying-Hsi Lin and Shengjie Lu
submission deadline 31 Jan 2026 | Viewed by 256 | Submission Open
Keywords: heart failure; cardiac remodelling; contractile dysfunction; bioenergetics; gene replacement or editing
(This special issue belongs to the Section Molecular Medicine)
Advances in Molecular Therapy Targeting DNA Damage and Repair Systems
edited by , and Anahita Mojiri
submission deadline 31 Jan 2026 | Viewed by 251 | Submission Open
Keywords: DNA repair; DNA repair inhibitors; homologous recombination; genome instability; inflammation; DNA damage; cell death; apoptosis
(This special issue belongs to the Section Biological Factors)
Mechanisms of Gene Regulation in Embryos
edited by and Adam Davis
submission deadline 31 Jan 2026 | Viewed by 249 | Submission Open
Keywords: embryonic development; gene regulation; epigenetics; transcriptional control; post-transcriptional control; translational control; post-translational modification; signaling pathways; developmental disorders
(This special issue belongs to the Section Molecular Biology)
The Role of Extracellular Vesicles in Drug Delivery
edited by
submission deadline 31 Jan 2026 | Viewed by 227 | Submission Open
Keywords: extracellular vesicles; drug delivery systems; extracellular vesicle engineering; cancer treatment; gene therapy
(This special issue belongs to the Section Molecular Biology)
Molecular Mechanisms, Novel Diagnostics and Treatments of Gynecologic Cancer
edited by Panneerdoss Subbarayalu
submission deadline 31 Jan 2026 | Viewed by 140 | Submission Open
Keywords: biomarker; cancer biology; novel drug targets and therapeutics; cancer stem cells; tumorigenesis
(This special issue belongs to the Section Molecular Medicine)
New Insights into Mesothelial Cell
edited by Francesca Bodega and Cristina Porta
submission deadline 31 Jan 2026 | Viewed by 119 | Submission Open
Keywords: mesothelial cells; serous cavities; lubricating fluids; epithelial– mesenchymal transition; fibrosis; tissue repair; mesothelioma; tumor microenvironment; immune response
(This special issue belongs to the Section Molecular Biology)
Epigenetic Regulation of Vascular Smooth Muscle Cells During Development and Disease submission deadline 31 Jan 2026 | Viewed by 108 | Submission Open
Keywords: vascular smooth muscle cells; cell phenotypic change; epigenetics; gene expression regulation; cell differentiation
(This special issue belongs to the Section Molecular Biology)
Metabolic Diseases: From Molecular Mechanisms to Therapy Strategies submission deadline 31 Jan 2026 | Viewed by 106 | Submission Open
Keywords: inborn errors of metabolism; molecular mechanisms; gene identification; therapeutic; approaches; translation
Mechanisms in Stress-Related Disorders, Anxiety and Fear
edited by Veronica Begni
submission deadline 31 Jan 2026 | Viewed by 77 | Submission Open
Keywords: stress-related disorders; anxiety; fear; genetic and environmental interactions; behavioral neuroscience; biological pathways; biomarkers; therapeutic interventions
(This special issue belongs to the Section Molecular Biology)
Nucleic Acid-Lipid Interactions: Bridging Molecular Insights with Therapeutic Applications
edited by Weiwei He and Serdal Kirmizialtin
submission deadline 31 Jan 2026 | Viewed by 56 | Submission Open
Keywords: nucleic acids; lipid membranes; interactions; structural transitions; physical mechanism
Effects of Weightlessness on Molecular Changes in Cellular Organisms, Animals and Plants: 2nd Edition
edited by
submission deadline 31 Jan 2026 | Viewed by 51 | Submission Open
Keywords: cells; humans; animals; plants; microorganisms; microgravity; weightlessness; cancer research; tissue engineering; space-related health problems
(This special issue belongs to the Section Cellular Biochemistry)
New Insights into Mechanisms and Therapeutics for Cardiovascular Disorders: 2nd Edition
edited by , and Tarun W. Dasari
submission deadline 31 Jan 2026 | Viewed by 49 | Submission Open
Keywords: brain– heart axis; heart and stroke; stress-induced cardiomyopathy; cardiovascular disease
(This special issue belongs to the Section Molecular Medicine)
Endometriosis: Molecular Pathogenesis and Translational Implications
edited by
submission deadline 31 Jan 2026 | Viewed by 46 | Submission Open
Keywords: endometriosis; pathogenesis; adenomyosis; diagnosis; detection
(This special issue belongs to the Section Molecular Medicine)
Alcohol Consumption as a Cardiovascular Risk Factor: Focusing on Molecular Mechanisms submission deadline 31 Jan 2026 | Viewed by 38 | Submission Open
Keywords: alcohol; ethanol metabolism; ethanol– protein interactions; ethanol– membrane interactions; cardiovascular health and disease
(This special issue belongs to the Section Molecular Medicine)
Lung Disease: From Molecular Mechanism to Therapeutic Opportunities
edited by
submission deadline 31 Jan 2026 | Viewed by 35 | Submission Open
Keywords: biomarkers; pharmacotherapeutics; cell signaling; innate immunity; inflammation
(This special issue belongs to the Section Molecular Biology)
Molecular Biology and Therapy of Breast Cancer
edited by
submission deadline 31 Jan 2026 | Viewed by 32 | Submission Open
Keywords: breast cancer; molecular pathology; biomarkers; novel therapy targets; personalized therapy; immunotherapy; tumor microenvironment; tumor stem cells; therapy resistance; non-coding RNA
Synthesis, Characterization and Validation of Small Molecule Compounds
edited by Mohamed Fares Metwaly
submission deadline 31 Jan 2026 | Viewed by 29 | Submission Open
Keywords: medicinal chemistry; structure-based drug design; enzyme inhibitors; multi-target therapeutics
(This special issue belongs to the Section Molecular Biology)
Pain and Therapy: Molecular Perspectives and Future Directions submission deadline 31 Jan 2026 | Viewed by 27 | Submission Open
Keywords: pain; nociceptive pain; neuropathic pain; neoplastic pain; pain physiology; pain treatment
(This special issue belongs to the Section Molecular Biology)
Sterol Biosynthesis in Organisms
edited by Damjana Rozman and
submission deadline 31 Jan 2026 | Viewed by 26 | Submission Open
Keywords: sterol biosynthesis; sterol metabolism; sterol regulation; sterol-related diseases
(This special issue belongs to the Section Cellular Biochemistry)
Genetic and Epigenetic Mechanisms Underlying Neurodevelopmental Disorders
edited by
submission deadline 31 Jan 2026 | Viewed by 16 | Submission Open
Keywords: neurodevelopmental disorders; epigenetics; gene– environment interaction; chromatin remodeling; neurogenomics
(This special issue belongs to the Section Molecular Genetics)
Advances and Novel Strategies for Studying Underexplored Post-Translational Modifications (PTMs)
edited by
submission deadline 31 Jan 2026 | Viewed by 11 | Submission Open
Keywords: post-translational modifications proteomics; chemical biology; cell signaling; epigenetics; metabolic regulation; cancer; diabetes; microbiome; aging
(This special issue belongs to the Section Molecular Biology)
Regulation of Sperm Function and Embryo Development submission deadline 31 Jan 2026 | Viewed by 8 | Submission Open
Keywords: sperm; oocyte; embryo; genes; reproductive technologies
(This special issue belongs to the Section Molecular Reproduction)
Pathogenesis and Targeted Therapy of Neurodegenerative Diseases submission deadline 31 Jan 2026 | Submission Open
Keywords: neurodegeneration; neurodegenerative diseases; targeted therapy; molecular mechanisms; disease-modifying treatments
(This special issue belongs to the Section Molecular Medicine)
Back to TopTop