The Future of Protein Research: New Paradigms and Transformative Technologies
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Biomacromolecules: Proteins, Nucleic Acids and Carbohydrates".
Deadline for manuscript submissions: 31 December 2026 | Viewed by 94
Special Issue Editor
2. Department of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, QC H3T 1J4, Canada
Interests: protein–protein interactions; PAQosome; molecular chaperones; AlphaFold-pairs software; zoonotic respiratory viruses; protein complex assembly; antivirals; proteomics; PAQosome cochaperone; RNA polymerase; phage display; AlphaFold modeling
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Protein science is entering a transformative era. Breakthroughs in cryo-electron microscopy, single-cell and spatial proteomics, and increasingly powerful AI-driven approaches (including structure prediction and interaction modeling) are not only accelerating discovery—they are redefining how we conceptualize protein function, interaction networks, and therapeutic intervention.
This Special Issue of Biomolecules is designed to capture this moment of transition.
Rather than focusing solely on traditional reviews, we aim to assemble a collection of forward-looking, high-impact contributions that articulate emerging directions, challenge existing paradigms, and outline the next frontiers in protein research.
We particularly welcome reviews, perspectives, opinions, and commentaries that:
- Provide new conceptual frameworks or reinterpret established fields;
- Highlight emerging technologies shaping protein science;
- Explore complex protein systems, including interactomes and dynamic assemblies;
- Address translational opportunities, including drug discovery and synthetic biology;
- Discuss the integration of AI and data-driven approaches into protein research.
We encourage contributions from leading experts, established investigators, and members of the Biomolecules editorial community, with the goal of creating a selective and authoritative issue that reflects both depth and vision.
Our ambition is not only to summarize the state of the field but to define where it is going next.
By bringing together these perspectives, this Special Issue will serve as a reference point for future research, stimulate interdisciplinary dialogue, and help shape the evolving landscape of protein science.
Prof. Dr. Benoit Coulombe
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- protein science
- proteomics
- cryo-electron microscopy
- AI-driven approaches
- interactomes
- drug discovery
- synthetic biology
- protein structure and function
- protein engineering
- biophysics
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