Bone Tissue Morphology: From Pathophysiological Mechanisms to Regenerative Strategies

A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Medicine".

Deadline for manuscript submissions: 31 May 2026 | Viewed by 1

Special Issue Editor


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Guest Editor
Laboratory of Mineralized Tissues, Center for Translational and Clinical Research, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia
Interests: bone morphogenetic proteins; osteoprotegerin; cytokines; bone microarchitecture; bone metabolism; bone osteoporosis

Special Issue Information

Dear Colleagues,

Bone tissue plays multiple roles in the human body and is closely connected with various organ systems. Prominently, in the skeleton, it provides a scaffold for the specimen phenotype and protection for crucial organs. Besides these roles, it enables movement through muscle connection via tendons, facilitates hematopoiesis in bone marrow, and participates in calcium metabolism. Two processes mediate osteogenesis: endochondral bone formation through cartilaginous templates and intramembranous ossification through the direct condensation of bone-forming cells. A notable feature of the skeletal system is its high regeneration potential through cartilage and bone callus remodeling. Numerous disorders can influence bone formation, remodeling, and fracture repair, resulting in pathological changes to the skeletal morphology.

This Special Issue will showcase basic and translational research on pathophysiological mechanisms altering bone tissue morphology, experimental therapeutic advancements in fracture repair, and other strategies in regenerative medicine. Authors are invited to contribute comprehensive reviews and original research articles to this Special Issue.

Dr. Igor Erjavec
Guest Editor

Manuscript Submission Information

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Keywords

  • osteoporosis
  • bone cancer
  • fracture repair
  • regenerative biomaterials
  • bone remodeling
  • molecular mechanisms
  • biomechanical mechanisms
  • bone imaging techniques

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Published Papers

This special issue is now open for submission.
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