Amino Acids and Their Metabolism in Disease
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Biomacromolecules: Proteins, Nucleic Acids and Carbohydrates".
Deadline for manuscript submissions: 20 January 2027 | Viewed by 2574
Editor
Interests: pediatrics; Kawasaki disease; pentraxin 3; soluble pattern-recognition molecule; cytokines; enzyme preparations; cell death; sensitivity prediction; amino acid requirement; selective toxicity; pediatric hematology/oncology; amino acid metabolism; anticancer drugs; pediatric leukemia; flow cytometry; immunohistochemistry; monoclonal antibodies; asparagine synthetase; l-asparaginase; selective toxicity to cancer cells
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Amino acid metabolism is fundamental to cellular function, influencing protein synthesis, energy production, signaling pathways, and epigenetic regulation. Dysregulation of these pathways contributes to the development and progression of diverse diseases, including cancer, metabolic syndrome, neurological and psychiatric disorders, cardiovascular disease, and immune dysfunction.
This Special Issue seeks to present recent advances in our understanding of the roles of amino acids and their metabolic networks in human disease. We welcome original research and comprehensive reviews addressing the following:
* Mechanistic studies of amino acid metabolic pathways in disease pathophysiology;
* The role of transporters, sensors, and metabolic enzymes as potential therapeutic targets;
* Interactions between amino acid metabolism and the immune system, microbiome, or tumor microenvironment;
* Development of biomarkers or diagnostic tools based on amino acid metabolism;
* Innovative therapeutic approaches, including enzyme inhibition, depletion strategies, or dietary interventions;
* Technological and methodological advances in metabolomics, flux analysis, and systems biology related to amino acid research.
By synthesizing such contributions, this Special Issue aims to provide a comprehensive overview of the field and stimulate further research into the targeting of amino acid metabolism for improved disease management.
Prof. Dr. Toshiyuki Kitoh
Guest Editor
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- amino acid metabolism
- disease pathophysiology
- cancer metabolism
- immunometabolism
- metabolic reprogramming
- amino acid transporters
- therapeutic targeting
- biomarkers
- nutrient sensing
- systems biology
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