Amino Acids and Their Metabolism in Disease

Dear Colleagues,

Amino acid metabolism is fundamental to cellular function, influencing protein synthesis, energy production, signaling pathways, and epigenetic regulation. Dysregulation of these pathways contributes to the development and progression of diverse diseases, including cancer, metabolic syndrome, neurological and psychiatric disorders, cardiovascular disease, and immune dysfunction.

This Special Issue seeks to present recent advances in our understanding of the roles of amino acids and their metabolic networks in human disease. We welcome original research and comprehensive reviews addressing the following:

* Mechanistic studies of amino acid metabolic pathways in disease pathophysiology;

* The role of transporters, sensors, and metabolic enzymes as potential therapeutic targets;

* Interactions between amino acid metabolism and the immune system, microbiome, or tumor microenvironment;

* Development of biomarkers or diagnostic tools based on amino acid metabolism;

* Innovative therapeutic approaches, including enzyme inhibition, depletion strategies, or dietary interventions;

* Technological and methodological advances in metabolomics, flux analysis, and systems biology related to amino acid research.

By synthesizing such contributions, this Special Issue aims to provide a comprehensive overview of the field and stimulate further research into the targeting of amino acid metabolism for improved disease management.

Prof. Dr. Toshiyuki Kitoh
Guest Editor

Manuscript Submission Information

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